• This isolation limits toxicities which result from systemic chemotherapy treatments. (news-medical.net)
  • A comparison of regional and systemic chemotherapy for hepatic metastases. (ox.ac.uk)
  • In effect, part of the liver received regional chemotherapy, whereas the remainder of the organ was exposed to systemic chemotherapy. (ox.ac.uk)
  • Ultrasonography demonstrated shrinkage of the metastases in the area of liver receiving regional therapy, whereas disease progression occurred in the region of liver receiving 'systemic' treatment. (ox.ac.uk)
  • This patient demonstrates that tumour may respond to regional chemotherapy despite disease progression on systemic therapy and suggests that a controlled trial would yield valuable data. (ox.ac.uk)
  • Of the variety of tumors that are treated with this method, probably the most common indication are these low grade appendiceal cancers or what is clinically referred to as pseudomyxoma peritonei, and this is a situation in which patients can develop a significant amount of mucin in their abdomen, produced by the tumor cells that can be very problematic, and that may not necessarily be very responsive to conventional systemic therapies. (reachmd.com)
  • If the liver is the only site of metastatic disease, regional treatment options can offer the benefit of high local exposure with limited systemic toxicity, especially for patients without (further) systemic treatment options. (omicsdi.org)
  • Patients with more advanced disease are currently offered palliative treatment, including localized transarterial chemoembolization (TACE) or systemic chemotherapy. (biomedcentral.com)
  • The effect of systemic chemotherapy on peritoneal metastases is somewhat limited, possibly due to the presence of the peritoneum-plasma barrier that prevents effective drug delivery from systemic circulation into the peritoneal cavity [4]. (doczz.net)
  • Intraperitoneal (IP) chemotherapy administration bypasses the peritoneum-plasma barrier and maximizes the total amount of drug delivered into peritoneal tumor nodules while minimizing systemic drug exposure [5]. (doczz.net)
  • Crettenand F, Martin D, Cherix S, Demartines N, Matter M. Occurrence and prognosis of lymph node metastases in patients selected for isolated limb perfusion with soft tissue sarcoma. (jcancer.org)
  • Some patients received neoadjuvant chemotherapy and/or radiotherapy according to local protocols, while others benefited from primary ILP. (jcancer.org)
  • and how it helps radiation and chemotherapy treatments become more effective for patients. (clevelandclinic.org)
  • So, the treatment is given over a period of about one hour, and we try to make the patients feel as comfortable as possible and we turn down the lights and play some music. (clevelandclinic.org)
  • Delcath Systems, Inc. (Nasdaq: DCTH), a medical technology company testing its proprietary treatment method for primary and metastatic cancers to the liver, announced today that it has exceeded 90% enrollment reaching 85 patients for its pivotal Phase III Metastatic Melanoma Trial. (news-medical.net)
  • This clinical study is testing the Delcath PHP System(TM) for the regional delivery of melphalan to the liver to treat patients with metastatic cutaneous and ocular melanoma who have unresectable tumors in the liver. (news-medical.net)
  • Patients in the Phase III trial are randomized into one of two treatment arms, including immediate treatment with melphalan via the Delcath PHP System(TM) or treatment with best alternative care. (news-medical.net)
  • Following guidelines established by U.S. Food and Drug Administration under a Special Protocol Assessment (SPA), patients are permitted to 'cross-over' from the best alternative care arm to receive treatment with the Delcath System at the time of disease progression. (news-medical.net)
  • So, hyperthermic intraperitoneal chemotherapy, or HIPEC, is a procedure which involves infusing the peritoneal cavity in patients with advanced peritoneal surface malignancies with high-dose chemotherapy. (reachmd.com)
  • We offer screening, evaluation, and treatment for patients who suffer from PAD, as well as severe venous insufficiency. (insighthack.com)
  • Our building houses numerous specialists who we work closely with and many patients will never have to leave the campus to complete all phases of their diagnostic and treatment needs. (insighthack.com)
  • For over a hundred years, doctors have been trying to treat cancer patients by overheating tumor tissue. (german-medicalgroup.com)
  • Multicenter phase I/II study of nivolumab combined with paclitaxel plus ramucirumab as the second-line treatment in patients with advanced gastric cancer. (postersessiononline.eu)
  • Preliminary results in colorectal cancer (CRC) patients enrolled in the GATTO study, a phase I study of Tomuzotuximab in combination with Gatipotuzumab in patients with EGFR positive solid tumors. (postersessiononline.eu)
  • Patients with Epidermolysis Bullosa (EB) have a broad spectrum of need for pain and wound treatment, varying with the type of EB, the severity within that type, and the particular physical, emotional, and psychological milieu of each individual. (hrb.ie)
  • Communication Frameworks for Palliative Surgical Consultations: A Randomized Study of Advanced Cancer Patients. (viictr.org)
  • Further trials are warranted to improve treatment and life expectancy of patients suffering from fatal diseases such as pancreatic carcinoma. (omicsdi.org)
  • We report the results of our experience with isolated hepatic perfusion (IHP) in patients with isolated liver metastases from a variety of primary tumors. (omicsdi.org)
  • Suspected lung cancer, including characterisation of lung nodules (which are common in patients with pulmonary disease), is a common indication for PET/CT where biopsy may be challenging. (rcpjournals.org)
  • The aim of this study was to evaluate the influence of radiation dose on cardiac structures on the values of the early cardiotoxicity marker high-sensitivity cardiac troponin I (hscTnI) in patients with HER2-positive left breast cancer undergoing adjuvant concomitant antiHER2 therapy and radiotherapy, and to establish a correlation between the hscTnI values and cardiac radiation doses. (bvsalud.org)
  • PATIENTS AND METHODS: 3D-CRT and HT treatments were planned for 20 patients (pts). (bvsalud.org)
  • BACKGROUND: Left-sided breast cancer patients receiving adjuvant radiotherapy are at risk for coronary artery disease, and/or radiation mediated effects on the microvasculature. (bvsalud.org)
  • Sugarbaker, Paul H. 2011-10-16 00:00:00 Gastrointestinal Complications in 147 Consecutive Patients with Peritoneal Surface Malignancy Treated by Cytoreductive Surgery and Perioperative Intraperitoneal Chemotherapy 30). (sagepub.com)
  • Hyperthermic isolated hepatic perfusion using melphalan for patients with ocular melanoma metastatic to liver. (helsedirektoratet.no)
  • Clinical studies have shown that patients with highly hypoxic tumors have increased frequency of locoregional treatment failure, increased incidence of distant metastases and poor disease-free and overall survival rates following radiation therapy alone or radiation therapy combined with surgery and/or chemotherapy [ 1 ]. (biomedcentral.com)
  • Changes in regional cerebral blood flow associated with a 45 day course of the ketogenic agent, caprylidene, in patients with mild to moderate Alzheimer's disease: Results of a randomized, double-blinded, pilot study. (ucla.edu)
  • International Cognition and Cancer Task Force Recommendations for Neuroimaging Methods in the Study of Cognitive Impairment in Non-CNS Cancer Patients. (ucla.edu)
  • Methods: We evaluated whether surgery-related blood HGF elevation has prognostic significance in patients with surgically resected non-small cell lung cancer. (go.jp)
  • Conclusion: Elevation of HGF in plasma may be an important prognostic factor for early metastatic disease in patients with primary lung cancer. (go.jp)
  • Between December 2006 and December 2014, 53 patients with NMIBC who underwent TUR were randomly assigned to receive BHPC (BHPC group, 28 patients) or intravesical chemotherapy alone (chemotherapy group, 25 patients) at the Intracelom Hyperthermic Perfusion Therapy Center of Guangzhou Medical University Cancer Hospital (Guangzhou, China). (spandidos-publications.com)
  • BHPC was performed by combining perfusion-based hyperthermia with chemotherapeutic agent mitomycin C (MMC) in the bladder, and the chemotherapy group of patients received bladder MMC perfusion. (spandidos-publications.com)
  • Among patients with bladder cancer, ~75% are diagnosed with non-muscle invasive bladder cancer (NMIBC) which has a much more favorable prognosis than muscle-invasive bladder cancer ( 1 , 2 ). (spandidos-publications.com)
  • However, NMIBC recurs in ~70% of patients post-TUR, and requires lifelong treatment ( 3 - 6 ). (spandidos-publications.com)
  • Tens of thousands of patients have been treated for uterine fibroid, benign prostate hyperplasia, bone metastases, or prostate cancer. (biomedcentral.com)
  • However, to date, only about 25% of the patients with primary liver tumors are considered to be suitable candidates for curative treatment. (biomedcentral.com)
  • For example the 2010 Treatment Guidelines for hepatocellular carcinoma from the American Association for the Study of Liver Disease [ 3 ] stated that radiofrequency ablation should be offered to patients with three or fewer primary tumors of less than 3 cm each, yet HIFU has the potential to target and ablate non-invasively, and in one session, a higher number of lesions with lower treatment-related morbidity. (biomedcentral.com)
  • Curative treatments for patients with liver metastases can be aggressive in terms of the extent of damage to liver tissue since there is usually no underlying liver disease. (biomedcentral.com)
  • The hotline, dubbed the Complex Abortion Regional Line for Access, or CARLA, will be staffed by nurses who will aid patients by scheduling appointments within hospital systems and getting set up with any required pre-operative testing. (chicagobusiness.com)
  • Additionally, CARLA's partnership with the Chicago Abortion Fund will help patients with funding for reproductive health services, plus any transportation and child care costs while getting and recovering from treatment. (chicagobusiness.com)
  • Five of 21 patients with advanced cancers survived longer than 400 days after initiation of Nanotax® IP treatment. (doczz.net)
  • IV paclitaxel includes the solubilizing agent Cremophor [2] (polyoxyethylated castor oil) which, although generally recognized as safe, has been shown to be responsible for significant side effects necessitating pre-treatment of patients with antiemetics, antihistamines and either oral or IV steroids. (doczz.net)
  • BACKGROUND: Oxaliplatin and Mitomycin C (MMC) are both suitable as intraperitoneal chemotherapy agents in HIPEC for peritoneal carcinomatosis (PC) of colorectal cancer (CRC). (lu.se)
  • Hyperthermic intraperitoneal chemotherapy, or HIPEC, is one of the most innovative treatments available today for complex abdominal cancers. (reachmd.com)
  • Can you please just tell us what exactly is hyperthermic intraperitoneal chemotherapy? (reachmd.com)
  • Abstract Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) is increasingly used in the treatment of peritoneal carcinomatosis from gastrointestinal malignancies. (sagepub.com)
  • IVIM-DWI could efficiently assess tumor treatment response to fractional radiotherapy and predict the radio-sensitivity for NPCs. (e-crt.org)
  • The primary treatment regimen for NPCs is radiotherapy (RT) coupled with or without chemotherapy. (e-crt.org)
  • This heat application is intended to destroy cancer cells and make the tumor more sensitive, for example, to chemotherapy or radiotherapy. (german-medicalgroup.com)
  • BACKGROUND/AIM: To compare heart, left ventricle (LV) and coronary artery dose-sparing with three-dimensional conformal radiotherapy (3D-CRT) vs. helical tomotherapy (HT) in left-sided breast cancer (BC). (bvsalud.org)
  • It had substantial changes com- diotherapy [12], and chemotherapy-combined radiotherapy pared to the previous edition of classification published in 2007. (bvsalud.org)
  • Radiation Oncologist, Physician Scientist, and Founding Director of the Center for Hyperthermia at Cleveland Clinic, Jennifer Yu, MD, PhD, joins the Cancer Advances podcast to discuss hyperthermia therapy, which uses heat to destroy cancer cells and shrink tumors. (clevelandclinic.org)
  • And so, the idea is direct exposure of chemotherapy at doses that would be not tolerable to be given systemically, directly onto the surfaces where tumors were, and at a time when the tumor burden is lowest. (reachmd.com)
  • After the tumors have been removed, we introduce catheters into the abdomen and infuse the chemotherapy for approximately 90 minutes under heated conditions, typically 41 to 43° centigrade. (reachmd.com)
  • For one, it is thought that the-and there is some preclinical data to suggest this-the heat seems to be more effective against disruption of cancer cells and increases the vascular permeability of the chemotherapies into the tumors themselves. (reachmd.com)
  • We are mainly interested in regional hyperthermia of deep seated tumors. (ichmt.org)
  • Perfusion imaging of brain tumors has been performed by using various tracer and nontracer modalities and can provide additional physiologic and hemodynamic information, which is not available with routine morphologic imaging. (ajnr.org)
  • Traditionally, perfusion imaging of brain tumors has been performed with MR imaging, by using various perfusion imaging techniques and estimating tumor blood volume, blood flow, and permeability. (ajnr.org)
  • In view of the wider availability, faster scanning times, and low cost compared with MR perfusion, PCT is potentially well-suited to study brain tumors 6 , 7 and could potentially be useful as an easy tool for quantitative estimates of perfusion parameters and their use as imaging biomarkers. (ajnr.org)
  • Tumors increasing beyond the posterior fossa had been included only when the HA-1077 supplier main tumor part was inside the cerebellum and if the scientific data backed a mainly cerebellar origins. (tam-receptor.com)
  • Over recent decades, there has been an increasing interest in the employment of hyperthemia at 40̊C and above in the treatment of malignant tumors ( 13 , 16 , 18 - 20 ). (spandidos-publications.com)
  • The head and neck regions were constituted to have high anatomical and functional difficulties, making the accurate diagnosis and staging of regional tumors a challenging task. (springeropen.com)
  • MRI sequences provided us with very accurate data about tumor size, site, and morphological criteria of tumors in the head and neck areas. (springeropen.com)
  • The National Comprehensive Cancer Network (NCCN) Soft Tissue Sarcoma Panel specifically identifies Li-Fraumeni syndrome and familial adenomatous polyposis (FAP) as genetic cancer syndromes with a predisposition for the development of STS, along with Carney-Stratakis syndrome, which is associated with gastrointestinal stromal tumors (GISTs) and paragangliomas. (medscape.com)
  • The World Health Organization classification system for tumors of the soft tissue and bone incorporates detailed cytogenetic and molecular data into the classifications. (medscape.com)
  • Notably, radio-resistance, tumor recurrence, and the development of distant metastases remain the contributing reasons for treatment failure. (e-crt.org)
  • A 48-year-old man with colorectal liver metastases underwent insertion of an hepatic arterial infusion catheter for regional chemotherapy. (ox.ac.uk)
  • Progression of liver metastases was documented in one and stable disease in another patient two months after treatment. (omicsdi.org)
  • Isolated hepatic perfusion with 200 mg melphalan for advanced noncolorectal liver metastases. (omicsdi.org)
  • With approximately 250,000 cases of primary or secondary cancer of the liver diagnosed each year in the U.S. and 2.6 million cases globally, we believe our Percutaneous Hepatic Perfusion (PHP(TM)) technology is a compelling proposition,' said Eamonn Hobbs, President and CEO of Delcath Systems. (news-medical.net)
  • Postoperative hepatic arterial perfusion scintigraphy showed that only part of the liver was being perfused by this route. (ox.ac.uk)
  • VAC's scope of practice includes complete dialysis access maintenance services, limb salvage, venous and arterial disease treatment, and other related work. (insighthack.com)
  • As a result, the system showed relative changes of the flow during the arterial perfusion periods. (spie.org)
  • Today I'm happy to be joined by Dr. Jennifer Yu, a radiation oncologist at the Taussig Cancer Institute, and a cancer researcher in the Lerner Research Institute's Department of Cancer Biology. (clevelandclinic.org)
  • Just application of heat in combination with radiation or with chemotherapy can make it so effective with very few side effects. (clevelandclinic.org)
  • Intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI)was evaluated regarding its ability to preliminarily predict the short-term treatment response of nasopharyngeal carcinoma (NPC) following intensity-modulated radiation therapy. (e-crt.org)
  • Treatment usually involves surgery, after which chemotherapy and radiation therapy are used. (wikipedia.org)
  • Tumor vascular perfusion parameters obtained by using CT or MR perfusion have been used for tumor grading, prognosis, and treatment response in addition to differentiating treatment/radiation effects and non-neoplastic lesions from neoplasms. (ajnr.org)
  • The study suggested that clinical micrometastases may be resistant to ionizing radiation and chemotherapy before they induce angiogenesis, and that vascularized micrometastases may not show hypoxia-induced treatment resistance. (biomedcentral.com)
  • More recently, a review has shown that ILP was an acceptable modality for neoadjuvant treatment of limb STS initially regarded as unresectable [ 7 ]. (jcancer.org)
  • We examined blood HGF concentration, c-met expression, and postoperative prognosis of 25 cases of primary resected, non-small cell lung cancer. (go.jp)
  • There were two postoperative deaths: one was from an unknown cause, 8 months postoperatively and another was from a lung cancer recurrence, 9 months after surgery. (go.jp)
  • Glioblastoma, previously known as glioblastoma multiforme (GBM), is the most aggressive and most common type of cancer that originates in the brain, and has very poor prognosis for survival. (wikipedia.org)
  • (2) A few children have survived more than three years post-treatment, providing glimmers of hope that CED may prove to be an essential tool for changing DIPG's typically dire prognosis. (mskcc.org)
  • Perfusion imaging has been used to assess tumor grade and prognosis and, recently, to assess treatment response, which has attracted more attention due to the advent of newer therapeutic options, including antiangiogenic agents. (ajnr.org)
  • Cognitive function after the initiation of adjuvant endocrine therapy in early-stage breast cancer: an observational cohort study. (ucla.edu)
  • So, you mentioned previously local hyperthermia, regional hyperthermia, whole body hyperthermia and you gave the fever example. (clevelandclinic.org)
  • Bladder intracavitary hyperthermic perfusion chemotherapy (BHPC), the combination of local hyperthermia with chemotherapy, can significantly improve the effect of intracavity chemotherapy, and is reported to have an additive or supra-additive effect, preventing NMIBC recurrence post-TUR ( 13 - 16 , 18 - 20 ). (spandidos-publications.com)
  • However, these previous conventional trials were based on hot water-, microwave- or radiofrequency-induced local hyperthermia, either individually or in combination with cytostatic agents, which could maintain continuous and stable treatment temperatures, but lack effective temperature control or regulation, and cannot provide uniform distribution of heat to the bladder. (spandidos-publications.com)
  • Western Vascular Institute is dedicated to providing the highest quality vascular treatment options available for each patient's individual needs, as well as unparalleled patient care. (insighthack.com)
  • Many of us in contrast PCC principles in between Non-Hispanic White-colored (Bright BVS bioresorbable vascular scaffold(s) ), Hispanic, along with Non-Hispanic Dark (Dark) cancers individuals using Critical Race Idea (Cathode ray tube) to be aware of the actual interactions involving racial-ethnic identification and PCC. (statsignals.com)
  • 3 - 5 However, PCT, which has also been used recently for glioma grading, 6 , 7 provides a linear relationship between tissue attenuation and tissue concentration of a contrast agent, unlike perfusion MR imaging, and, hence, probably provides a more robust and less biased estimation of hemodynamic (tumor blood volume) and physiologic (tumor vascular leakiness) parameters. (ajnr.org)
  • Cancer Advances, a Cleveland Clinic podcast for medical professionals exploring the latest innovative research and clinical advances in the field of oncology. (clevelandclinic.org)
  • Rather, survival seems to be primarily correlated with the histologic features, clinical findings (age at onset, epilepsy vs deficit), and radiologic criteria (especially contrast enhancement and perfusion-weighted imaging). (medscape.com)
  • The nonlinear model predicts that a much larger amount of muscle tissue is heated to above 40 o C. In spite of the fact that only a small number of temperature measurements from inside the body is available, this effect might be visible in clinical data. (ichmt.org)
  • Convection enhanced delivery (CED), an innovative technique that directly infuses a therapeutic agent into a brain tumor through a cannula, bypassing the blood-brain barrier (BBB), is safe and feasible for treating diffuse intrinsic pontine glioma (DIPG), according to our experience to date in an ongoing phase I clinical trial at Memorial Sloan Kettering Cancer Center (MSK). (mskcc.org)
  • Hence, there is a need for noninvasive in vivo clinical imaging tools that can study perfusion in the entire tumor, can be used to assess much larger volumes than small biopsy samples, and can probably guide biopsy and excision sites for better results. (ajnr.org)
  • Clinical cancer research, 9(17), 6343-6349. (helsedirektoratet.no)
  • Long-Term Clinical and Neuronuclear Imaging Sequelae of Cancer Therapy, Trauma, and Brain Injury. (ucla.edu)
  • Clinical cancer research : an official journal of the American Association for Cancer Research, 2014. (ucla.edu)
  • These inadequate devices for local heat delivery lack appropriate methods for monitoring temperature at the targets, limiting the application of hyperthermia enhanced therapy for cancer in clinical practice. (spandidos-publications.com)
  • Despite the methods' clinical potential, the liver is a particularly challenging organ for HIFU treatment due to the combined effect of respiratory-induced liver motion, partial blocking by the rib cage, and high perfusion/flow. (biomedcentral.com)
  • A review of current unmet clinical needs is given here, as well as a consensus from a panel of experts about technical and clinical requirements for upcoming pilot and pivotal studies in order to accelerate the development and adoption of focused ultrasound for the treatment of primary and secondary liver cancer. (biomedcentral.com)
  • Gd chelates are used routinely in clinical practice with T2-weighted imaging for cerebral perfusion studies, Inverness was rebuilt over the last 150 years or so. (top5binarybrokers.com)
  • The NCT Lung CP is based on the clinical backbone of the Thoraxklinik Heidelberg, an internationally renowned, comprehensive center for the treatment of lung diseases. (nct-heidelberg.de)
  • On univariate analysis of grade I-IV events a statistically significant association was observed with the following variables: histological grade, peritoneal cancer index (PCI), small bowel resection, colorectal anastomosis, and the number of anastomoses performed per patient. (sagepub.com)
  • Preventing the recurrence of non-muscle invasive bladder cancer (NMIBC) post-transurethral resection (TUR) remains challenging. (spandidos-publications.com)
  • Transurethral resection (TUR) has been shown to be an efficient and safe method for the treatment of NMIBC. (spandidos-publications.com)
  • Purpose: Hepatocyte growth factor (HGF), a ligand of the c-met proto-oncogene, exhibits activating effects on human lung cancer both in vitro and in vivo. (go.jp)
  • Moreover, inhibition of HGF elevation may have therapeutic effects on early distant metastasis of lung cancer. (go.jp)
  • As recent data-driven respiratory gating (DDG) [18F]-FDG has shown superior diagnostic performance in lung cancer, we evaluated the impact of DDG on the reproducibility of radiomics features derived from [18F]-FDG PET/CT in comparison to free-breathing flow (FB) imaging. (hes-so.ch)
  • The risk of lung cancer increases with combined exposure to toxins and cigarette smoking. (msdmanuals.com)
  • The lung cancer risk associated with electronic nicotine delivery systems (eg, e-cigarettes) remains to be determined, although it is thought that the products of combustion of tobacco are the primary carcinogens. (msdmanuals.com)
  • About 15 to 20% of people who develop lung cancer have never smoked or have smoked minimally. (msdmanuals.com)
  • Chronic inflammation increases the risk of many cancers, including lung cancer. (msdmanuals.com)
  • In this study, the objective is to evaluate corresponding changes in perfusion, in the same cohort, where resting myocardial blood flow (MBF) was quantitatively measured. (bvsalud.org)
  • An in-depth report on the causes, diagnosis, treatment, and prevention of melanoma and nonmelanoma skin cancers. (limamemorial.org)
  • Different skin cancers start in different cells of the skin. (limamemorial.org)
  • Based on the type of cell in which they originate, skin cancers are divided into two major groups: melanoma and non-melanoma skin cancers. (limamemorial.org)
  • Sunlight is the most important environmental cause of melanoma and other skin cancers, as well as premature skin aging (photoaging). (limamemorial.org)
  • Skin cancer is the most common malignancy diagnosed in the United States, and invasive melanoma represents about 1% of skin cancers but results in most deaths. (cancer.gov)
  • My primary focus is on brain cancers, and I also am a leader of the Developmental Therapeutics program at the Case Comprehensive Cancer Center, and the founding director of the Center for Hyperthermia here at the Cleveland Clinic. (clevelandclinic.org)
  • So similarly, here we use heat therapy or hyperthermia to fight off cancers. (clevelandclinic.org)
  • Give us a little bit of an idea what local or regional hyperthermia might be. (clevelandclinic.org)
  • Hyperthermia - an overview: What is meant by cancer medicine? (german-medicalgroup.com)
  • With hyperthermia treatment, the tumor tissue is also heated from the outside. (german-medicalgroup.com)
  • Hyperthermia, i.e., heating tissue to 42 43 o C, is a method of cancer therapy. (ichmt.org)
  • As bladder cancer can be hypoxic, this provides a very strong rationale for the use of MMC in combination with hyperthermia ( 21 ). (spandidos-publications.com)
  • Hyperthermia treatment modalities have yet to progress from a bio-medical experiment to a clinically proven treatment ( 1 , 2 ). (spandidos-publications.com)
  • Hyperthermia is a technically challenging treatment modality. (spandidos-publications.com)
  • He provides wellness exams of diabetic feet, amputation prevention, limb salvage, ulceration treatment, and sports medicine foot care for casual and professional athletes. (insighthack.com)
  • For more information about risk factors, see Skin Cancer Prevention and Genetics of Skin Cancer . (cancer.gov)
  • The aim of the present study was to investigate the effectiveness and safety of bladder intracavitary hyperthermic perfusion chemotherapy (BHPC) for prevention of NMIBC recurrence post-TUR. (spandidos-publications.com)
  • The medication temozolomide is frequently used as part of chemotherapy. (wikipedia.org)
  • Long-term results of primary transpupillary thermal therapy for the treatment of choroidal malignant melanoma. (helsedirektoratet.no)
  • The technique has been increasingly used since 1992, when a 90 % remission rate for STS treated by a combination of chemotherapy and Tumour Necrosis Factor alpha (TNFα) has been demonstrated [ 6 ]. (jcancer.org)
  • 1 FDG uptake occurs even in normal sized lymph nodes with tumour involvement, in bone marrow and some organs where CT can be less sensitive and where MRI has mostly provided regional rather than whole-body assessment. (rcpjournals.org)
  • Furthermore, FDG uptake differentiates viable tumour from fibrosis after treatment and FDG uptake changes faster during treatment than tumours change in size. (rcpjournals.org)
  • Neuroimaging biomarkers and cognitive function in non-CNS cancer and its treatment: current status and recommendations for future research. (ucla.edu)
  • CONCLUSION: The combination therapy of viral gene transfer and chemotherapy temporarily controls and diminishes tumor burden. (omicsdi.org)
  • Functional imaging, that is, modalities that offer information on factors that influence treatment outcome (e.g., tumor burden, proliferation, and hypoxia), is expected to provide the biologic target volume for such dose painting ( 2 , 3 ). (snmjournals.org)
  • Multiple myeloma (MM) is an incurable cancer in which uncontrolled plasma cell proliferation disrupts the bone marrow environment and impairs immune function. (hrb.ie)
  • There may be some direct cytotoxic effect of heat to the cancer cells, which is somewhat selective to cancer versus normal cells. (reachmd.com)
  • Uveal melanomas differ significantly from cutaneous melanoma in incidence, prognostic factors, molecular characteristics, and treatment. (cancer.gov)
  • The purpose of this study is to reevaluate the incidence of gastrointestinal events and identify risk factors associated with this treatment approach. (sagepub.com)
  • Melanoma, derived from melanocytes, is the deadliest form of skin cancer. (limamemorial.org)
  • The risk of melanoma and nonmelanoma skin cancer rises with more frequency and length of time using indoor tanning devices, especially when tanning starts young (in the teenage and early 20s). (limamemorial.org)
  • A number of biologic agents have been approved or are being studied for the treatment of high-risk melanoma. (limamemorial.org)
  • For more information, see Intraocular (Uveal) Melanoma Treatment . (cancer.gov)
  • however, melanoma is the most common cancer in young adults aged 25 to 29 years and the second most common cancer in those aged 15 to 29 years. (cancer.gov)
  • 3 ] Ocular melanoma is the most common cancer of the eye, with approximately 2,000 cases diagnosed annually. (cancer.gov)
  • The National Cancer Data Base report on cutaneous and noncutaneous melanoma: a summary of 84,836 cases from the past decade. (helsedirektoratet.no)
  • 8 Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore. (aacrjournals.org)
  • PET/CT has mainly been used in oncology, with increased glucose metabolism occurring in most cancers, imaged with 18F-fluorodeoxyglucose (FDG). (rcpjournals.org)
  • Cisplatin, any platinum-based anticancer drug, creates reactive o2 types (ROS) in many cellular varieties and brings about mechanical allodynia in your hands and/or feet (chemotherapy-induced distressing neuropathy CIPN). (statsignals.com)
  • This research will provide a much better understanding of chronic dental ache in most cancers people.The existing conclusions suggest that cisplatin triggers TRPA1-mediated CIPN due to ROS age group inside the mouth location. (statsignals.com)
  • From diagnosis to treatment, our experts provide the care and support you need, when you need it. (mskcc.org)
  • Although DW-MRI in diagnosis of head and neck masses had been well analyzed in previous studies, the choice of suitable b value for imaging is still a diagnostic dilemma as factors causing passive diffusion, such as capillary perfusion, can contribute to decreased signal-to-noise ratio (SNR) in low b value DW-MRI. (springeropen.com)
  • It has revolutionized disease treatment methodologies and chronic disease diagnosis. (theinsightpartners.com)
  • Extracted data from medical files included demographics, surgical reports, radiological findings, pathological reports and follow-up. (jcancer.org)
  • Our goal is to present you with the optimal selection of renowned doctors and their modern and gentle surgical and treatment methods when you are looking for specialists. (german-medicalgroup.com)
  • Histologic evaluation of tumor angiogenesis by using various markers such as MVD, MVCP, and TVA is also limited by this regional heterogeneity, and its confounding effect is worsened by its small size and a limited number of samples obtained with surgical biopsy. (ajnr.org)
  • Despite advances in chemotherapeutics and surgical procedures, the 5-year survival rate for ovarian cancer was 45 % as of 2010 [1]. (doczz.net)
  • This treatment method allows high-dose areas to be conformed tightly to the target volumes, with dose falling off steeply outside these regions. (snmjournals.org)
  • A valid imaging modality was explored to assess the treatment responses of NPCs. (e-crt.org)
  • Primary liver cancer occurs most commonly in previously damaged livers, as in cases of viral hepatitis, alcohol abuse, obesity, and exposure to aflatoxin. (biomedcentral.com)
  • So for a variety of reasons, the heat can increase the efficacy of the chemotherapy alone under normothermic conditions. (reachmd.com)
  • The Delcath PHP System(TM) is designed to deliver significantly higher doses of anti-cancer drugs to a patient's liver while minimizing entry of the drugs into the rest of the patient's circulation. (news-medical.net)
  • It is normally applied as an additive therapy to enhance the effect of conventional radio- or chemotherapy. (ichmt.org)
  • In vivo perfusion imaging techniques provide additional information regarding tumor physiology and hemodynamics, which may help in better characterizing glioma malignancy and may also overcome some of the limitations of histologic grading and conventional morphologic imaging. (ajnr.org)
  • Treatment of dilated cardiomyopathy is essentially the same as treatment of chronic heart failure (CHF). (medscape.com)
  • Disease-free survival correlated negatively with the maximum tissue-to-blood 18 F-fluoromisonidazole ratio (T/B max ) on the baseline 18 F-fluoromisonidazole scan ( P = 0.04), with the size of the initial hypoxic volume ( P = 0.04), and with T/B max on the 18 F-fluoromisonidazole scan during treatment ( P = 0.02). (snmjournals.org)
  • To characterize the type from the hMSC-derived cartilaginous tissue attained by GNAS treatment with the various compounds, gene-expression adjustments of the -panel of transient or articular cartilage personal genes were assessed by quantitative RT-PCR. (bakingandbakingscience.com)
  • The optimal parameters based on the nonlinear model differ significantly from those obtained with constant-rate perfusion, they are in general closer to a symmetric configuration. (ichmt.org)
  • Treatment of liver cancer involves multiple strategies used independently, or in combination, depending on the stage of the disease. (biomedcentral.com)
  • IP paclitaxel administered in combination with IV (IV/IP) chemotherapy with or without IP platinum has been reported as a viable treatment approach for ovarian and peritoneal carcinomas. (doczz.net)
  • The risk of cancer differs by age, smoking intensity, and smoking duration. (msdmanuals.com)
  • Partner with us to treat your patient's cancer. (mskcc.org)
  • Our scientists pursue every aspect of cancer research-from exploring the biology of genes and cells, to developing immune-based treatments, uncovering the causes of metastasis, and more. (mskcc.org)
  • They were compared for toxicity and survival data. (lu.se)