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  • cytotoxic
  • Treatment of relapsed/refractory myeloma is based on double or triple combinations with a novel agent such as lenalidomide or bortezomib with dexamethasone and/or cytotoxic drugs such as alkylators and anthracyclines. (knowcancer.com)
  • Cancers
  • The high rate of mortality of patients diagnosed with brain cancers and in particular with glioblastoma multiforme (the most lethal and devastating form) is driving the scientific community to discover and develop improved treatments that could increase the survival time and enhance the quality of life of patients. (drugs.com)
  • non-small cell lung cancers are more likely to be contained in one area, making treatment more likely to be successful. (drugs.com)
  • Some trials continue to research hyperthermia in combination with other therapies for the treatment of different cancers. (cancertutor.com)
  • Symptoms
  • The goal of palliative care is to prevent or treat as early as possible the symptoms of a disease, side effects caused by treatment of a disease, and psychological, social, and spiritual problems related to a disease or its treatment. (ohsu.edu)
  • Resistance
  • This thesis describes studies based on microarray expression analysis and high-throughput compound screening for identification of resistance mechanisms, drug targets and diagnostic markers. (diva-portal.org)
  • patients
  • In 3 small studies of CoQ10 in breast cancer patients, some patients appeared to be helped by the treatment. (cancer.gov)
  • Interest in CoQ10 as a possible treatment for cancer began in 1961, when it was found that some cancer patients had a lower than normal amount of it in their blood . (cancer.gov)
  • However, cancer treatment in general can affect the ability of some patients to drive or operate machines. (drugs.com)
  • Male patients undergoing cytarabine treatment should use a reliable contraceptive method. (drugs.com)
  • ICT-121, which may have applicability to multiple types of cancer, will target glioblastoma in the initial Phase I trial," stated Manish Singh, Ph.D. "With the great unmet need represented by glioblastoma across all age groups, we are hopeful that an immunotherapy, such as ICT-121 or ICT-107, may someday offer patients a more effective and safer treatment alternative. (drugs.com)
  • Dr. Michael Berens, Director of TGen's Cancer and Cell Biology Division, said the recent findings are a major step toward devising a treatment for GBM, which because of its ability to rapidly grow within the brain often means patients have little time to survive. (eurekalert.org)
  • The purpose of this study is to see if treatment with PEG-interferon-alfa-2a (PEG-IFN) plus ribavirin is a more effective treatment for hepatitis C virus (HCV) than interferon-alfa-2a (IFN) plus ribavirin for patients infected with both HCV and HIV. (clinicaltrials.gov)
  • PEG-IFN is a modified form of IFN that stays in the blood longer, which means that patients would not have to take the treatment as often. (clinicaltrials.gov)
  • Patients receive up to 48 weeks of treatment. (clinicaltrials.gov)
  • Patients who are not eligible for this treatment, due to advanced age, comorbidities or poor performance status, are routinely treated with a combination of melphalan, prednisone and a novel agent such as thalidomide, bortezomib or lenalidomide. (knowcancer.com)
  • Patients will invariably relapse or become refractory to second and later line treatments. (knowcancer.com)
  • Therefore new treatment options for late-line patients are required. (knowcancer.com)
  • There are no approved treatment options for lenalidomide and bortezomib double-refractory patients. (knowcancer.com)
  • Therefore, treatment options for lenalidomide-refractory patients remain very limited. (knowcancer.com)
  • We appreciate the needs and expectations of our patients and take great pains to ensure that they are comfortable during their treatment and are made to feel like home. (placidway.com)
  • Attesting to this are patients from over 40 countries who have received high quality treatment in an environment specially designed to be healing and restful. (placidway.com)
  • To study radiobiological effects and drugs, which can modify radiation injury, has an importance if we would like to avoid harmful effects of radiation due to emergency situations or treat patients with malignant diseases by radiotherapy. (osti.gov)
  • During the long treatment schedules patients may be treated by not only anticancer but many other drugs because of accompanying diseases. (osti.gov)
  • Your help makes it possible to meet patients' needs, hold impactful conferences, develop fresh education programs and fund research for the cures, along with improved treatments until cures are discovered. (aamds.org)
  • After the first cycle, patients may continue to receive XMT-1522 until disease progression as long as the drug is well-tolerated and patients continue to derive clinical benefit in the opinion of the Investigator. (clinicaltrials.gov)
  • chemicals
  • When the DNA in a cell becomes damaged by agents such as toxic chemicals, radiation, or ultraviolet (UV) rays from sunlight, this protein plays a critical role in determining whether the DNA will be repaired or the damaged cell will self-destruct (undergo apoptosis). (nih.gov)
  • Its occurrence has been increasing with modernization and advancement perhaps due to environmental deterioration and increased exposure to chemicals and radiation. (lifehack.org)
  • chemotherapeutic
  • A chemotherapeutic treatment which targets these migrating cells would therefore have significant ramifications on patient survival," said Dr. Jennifer M. Eschbacher, a Neuropathology Fellow at Barrow Neurological Institute, who examined tumors for the study. (eurekalert.org)
  • liver
  • Before starting treatment with this medication, tell your doctor if you have liver or kidney problems. (webmd.com)
  • If your liver is not working well before treatment, cytarabine should be given only under strict control. (drugs.com)
  • bladder
  • Low-grade transitional cell carcinoma often recurs (comes back) after treatment, but rarely spreads into the muscle layer of the bladder or to other parts of the body. (cigna.com)
  • High-grade transitional cell carcinoma often recurs (comes back) after treatment and often spreads into the muscle layer of the bladder, to other parts of the body, and to lymph nodes. (cigna.com)
  • Mutations in the TP53 gene may help predict whether bladder cancer will progress and spread to nearby tissues, and whether the disease will recur after treatment. (nih.gov)
  • For this reason, people with bladder cancer typically need follow-up tests for years after treatment to look for bladder cancer that recurs or advances to a higher stage. (mayoclinic.org)
  • The type of bladder cancer determines which treatments may work best for you. (mayoclinic.org)
  • insulin
  • Treatment regimen for type 1 and type 2 diabetes differ in that type 1 diabetes treatment includes insulin while type 2 diabetes are cured by sulfonylureas (glibenclamide, glipizide), meglitinides (repaglinide), biguanides (metformin), thiazolidinediones (pioglitazone). (lifehack.org)
  • Rosiglitazone, an insulin-sensitizing drug, had no significant effect on bone marrow cellularity. (osti.gov)
  • hyperthermia
  • Embodiments of the present invention provide methods of detecting disease, methods of treating disease using targeted hyperthermia, methods of treating disease using targeted chemical agents, methods of treating disease comprising accurate measurements of the efficacy of treatments. (google.de)
  • The same nanoparticles can be used to facilitate hyperthermia treatments, and to allow targeted application of chemical therapeutic agents. (google.de)
  • Localized hyperthermia treatment is a well-established cancer treatment method with a simple basic principle: If a temperature elevation to 104ºF can be maintained for one hour within a cancer tumor, the cancer cells will be destroyed. (cancertutor.com)
  • According to the National Cancer Institute (National Institutes of Health), hyperthermia - a procedure in which body tissue is exposed to high temperatures (up to 113ºF) - is under investigation to assess its effectiveness in the treatment of cancer. (cancertutor.com)
  • This is dissimilar to the approach used at Hope4Cancer, where hyperthermia is combined with non-toxic alternative treatments to provide a safe and effective approach against cancer. (cancertutor.com)
  • tissue
  • This treatment exposes the body tissue to high temperatures, between 104º-113ºF (40°-45°C), without harming surrounding healthy tissue. (cancertutor.com)
  • effects
  • Drug interactions may change how your medications work or increase your risk for serious side effects. (medhelp.org)
  • Eating several small meals, not eating before treatment, or limiting activity may help lessen some of these effects. (medhelp.org)
  • These results suggest that NHERF-1 plays an important role in tumor biology, and that targeted inhibition of this factor may have significant effects on patient treatment and survival. (eurekalert.org)
  • These drugs may also modify radiobiological effects. (osti.gov)
  • Our new studies are designed to evaluate whether rosiglitazone has similar beneficial effects in radiation-damaged hemopoiesis. (osti.gov)
  • Side effects can happen with any type of treatment for salivary gland cancer, but everyone's experience is different. (cancer.ca)
  • vaccine
  • The main purpose of this study is to test the safety of a new vaccine, STEBVax, which may lead to a useful treatment for toxic shock syndrome. (clinicaltrials.gov)
  • An extremely complex drug, vaccine or antitoxin that is made from a living organism, or from products of a living organism. (ohsu.edu)
  • leukemia
  • The treatment of AML is different when it is a subtype called acute promyelocytic leukemia (APL) or when the child has Down syndrome . (cancer.gov)