Treatment of postmenopausal women. Medical search. Frequent questions

This study was undertaken to assess the effects of a low-fat dietary pattern on incidence of treated diabetes among generally healthy postmenopausal women. (healthpartners.com)
CONCLUSIONS: A low-fat dietary pattern among generally healthy postmenopausal women showed no evidence of reducing diabetes risk after 8.1 years. (healthpartners.com)
One large RCT, which focused on estrogen plus progestin versus placebo for primary prevention of coronary heart disease in healthy postmenopausal women, was stopped because hormonal treatment increased risks of invasive breast cancer, coronary events, stroke, and pulmonary embolism. (aafp.org)
Design and Participants: Healthy postmenopausal women (n = 51) consumed a controlled diet plus each of three treatments (a nonalcoholic placebo beverage or 15 or 30 g alcohol/d) during three 8-wk periods in random order under conditions of weight maintenance. (cdc.gov)
Conclusions: These results suggest that low to moderate daily alcohol consumption does not significantly affect 24-h urinary levels of melatonin among healthy postmenopausal women. (cdc.gov)
ABSTRACT To test the hypothesis that regional fat and not total body weight has a protective effect on bone mineral density (BMD) in postmenopausal women, a cross-sectional study was conducted during the period from March 2008 to June 2009 on 303 healthy postmenopausal women presenting to the osteoporosis unit for screening purposes. (who.int)

Hence, not surprisingly, postmenopausal women from different countries were reported to be particularly vulnerable to vitamin D deficiency, which leads numerous international health authorities and medical societies to produce recommendations for the management of postmenopausal osteoporosis by maintaining adequate vitamin D levels by supplementation. (hindawi.com)

What are the effects of treatments to prevent fractures in postmenopausal women? (aafp.org)

Larger studies are needed to inform clinical recommendations regarding the use of testosterone for HSDD in premenopausal women," the statement concludes. (medscape.com)
Importantly, treatment should target blood concentrations of testosterone that approximate what is normal for premenopausal women, and no higher, the statement recommends. (medscape.com)
We discovered that 52.5% of the Pap smears in postmenopausal women versus 33.6% in premenopausal women were classified as false positive (FP), with respect to the biopsy, and of these, 47.6 vs. 17% cases had no transformation zone (TZ) on the subsequent biopsies, respectively. (karger.com)
Group A: premenopausal women (n = 10), Group B: postmenopausal women, no osteoporosis, not on hormone replacement therapy (HRT) (n = 14), Group C: postmenopausal women, osteoporotic, not on HRT (n = 12), and Group D: postmenopausal women on HRT (n = 15). (annals.edu.sg)
Urinary D-Pyr results of postmenopausal women on HRT and premenopausal women showed no difference. (annals.edu.sg)
The prevalence of overweight and obesity is proportionally higher in postmenopausal women when compared with premenopausal women. (medscape.com)

Prevention of osteoporosis in postmenopausal women: 5 mg daily or 35 mg once weekly. (nih.gov)
FOSAMAX is indicated for the treatment and prevention of osteoporosis in postmenopausal women. (merck.com)
Prevention is the best treatment for osteoporosis. (everydayhealth.com)
From that, we may be able to develop better prevention and treatment in the future," Hudis said. (feelgoodnatural.com)
2. For prevention of postmenopausal osteoporosis: The lowest effective dose should be administered. (centerwatch.com)
Future research is needed to understand if prevention and treatment of osteoporosis may also help to control periodontal disease and tooth loss. (buffalo.edu)
Alternative strategies for prevention of postmenopausal osteoporosis. (cdc.gov)

In the study presented at the EULAR conference in Spain, however, Piet Geusens, of the Netherlands' Maastricht University and lead author, praised the new drug class' "highly effective treatment for postmenopausal women with osteoporosis with established bone mineral density (BMD) deficit who are at increased risk of fracture. (creakyjoints.org)
Thus, under the conditions of this study, the fluoride-calcium regimen was not effective treatment for postmenopausal osteoporosis. (elsevierpure.com)

About 25 million women pass through menopause worldwide each year, and it has been estimated that, by the year 2030, the world population of menopausal and postmenopausal women will be 1.2 billion, with 47 million new entrants each year. (wikipedia.org)
There is much anecdotal evidence of CBD's health benefits for menopausal and postmenopausal women, but our study is the first to investigate some of the claims in an established preclinical model of postmenopause. (eurekalert.org)

The objective of the present study was to examine the extent to which dried plum reverses bone loss in osteopenic postmenopausal women. (nih.gov)

Growth hormone treatment has sustained effects against problems associated with osteoporosis for years after it is stopped in postmenopausal women, suggests a new trial. (medicalnewstoday.com)
The authors of the study believe it is the largest and longest controlled study with growth hormone treatment in postmenopausal osteoporosis . (medicalnewstoday.com)
Years after treatment stopped, women who were treated with growth hormone still experienced improved bone density and reduced fracture risk. (medicalnewstoday.com)
Over the course of 18 months, 80 postmenopausal women with osteoporosis received daily injections of either a placebo , a single unit of growth hormone or a 2.5-unit dose of growth hormone in the randomized, double-blind trial. (medicalnewstoday.com)
Women on placebo stopped the injections after 18 months, while those randomized to growth hormone continued injections for a further 18 months. (medicalnewstoday.com)
The researchers continued to follow up the women for 7 years after the growth hormone treatment was halted, monitoring bone density, fractures and perceptions of quality of life. (medicalnewstoday.com)
A decade after the study began, the women who received the larger growth hormone dose still had higher bone mineral density levels than the participants who received the lower dose or the placebo. (medicalnewstoday.com)
The findings indicate the beneficial effects of growth hormone remained long after the treatment ceased. (medicalnewstoday.com)
Effect of growth hormone treatment on fractures and quality of life in postmenopausal osteoporosis: a 10-year follow-up study Emily Krantz et al. (medicalnewstoday.com)
One randomized controlled trial (RCT) involving women with prior vertebral fractures found that parathyroid hormone reduced the proportion of women with vertebral and nonvertebral fractures compared with placebo. (aafp.org)
Another RCT involving women with osteoporosis found that parathyroid hormone plus estrogen reduced vertebral fractures compared with estrogen alone after three years. (aafp.org)
One systematic review involving postmenopausal women found that hormone therapy reduced vertebral fractures compared with control. (aafp.org)
ARIMIDEX is indicated for adjuvant treatment of postmenopausal women with hormone receptor-positive early breast cancer . (rxlist.com)
ARIMIDEX is indicated for the first-line treatment of postmenopausal women with hormone receptor-positive or hormone receptor unknown locally advanced or metastatic breast cancer. (rxlist.com)
All of the treated women were receiving a stable dose of non-oral hormone replacement therapy. (sciencedaily.com)
Hormone therapy is currently not indicated for the treatment of postmenopausal confusion due to inefficacy. (wikipedia.org)
The use of hormone replacement therapy for approved indications has identified no significant negative effect on postmenopausal cognition. (wikipedia.org)
Although there are many relationships between hormone levels in postmenopause and cognitive function, the previously favored hormone replacement therapies (estrogen therapies) have been shown to be ineffective in specifically treating postmenopausal confusion. (wikipedia.org)
The use of hormone replacement therapies, once considered detrimental to cognition in postmenopausal women, has now been shown to have no negative effect when used properly for approved indications. (wikipedia.org)
Ferenczy A, Gelfand MM, Franco E, Mansour N: Human papillomavirus infection in postmenopausal women with and without hormone therapy. (karger.com)
Gupta S, Kumar N, Singhal N, Manektala U, Jain S, Sodhani P: Cytohormonal and morphological alterations in cervicovaginal smears of postmenopausal women on hormone replacement therapy. (karger.com)
New results from a substudy of the Women's Health Initiative (WHI) Estrogen-Alone Trial show that younger postmenopausal women who take estrogen-alone hormone therapy have significantly less buildup of calcium plaque in their arteries compared to their peers who did not take hormone therapy. (nih.gov)
These new results offer some reassurance to younger women who have had a hysterectomy and who would like to use hormone therapy on a short-term basis to ease menopausal symptoms," noted Elizabeth G. Nabel, M.D., NHLBI director. (nih.gov)
The new findings are from an ancillary study of 1064 women who were 50-59 years of age at the start of the WHI hormone therapy clinical trial. (nih.gov)
Conducting a clinical trial that would start any form of hormone therapy on postmenopausal women at a younger age and follow them for decades - when they would be more likely to have heart attacks - is not feasible. (nih.gov)
We cannot assume that any possible short-term, cardiovascular benefit from hormone therapy to postmenopausal women in their fifties would extend into older ages if they were to continue using hormones," Rossouw cautioned. (nih.gov)
We already know that starting hormone therapy in older women increases their risk of heart disease. (nih.gov)
The principal findings from the WHI hormone therapy trials, which studied 27,347 postmenopausal women on estrogen-alone or estrogen plus progestin, found that the overall risks of hormone therapy outweigh the benefits. (nih.gov)
We recruited 236 women, 1-10 years postmenopausal, not on hormone replacement therapy or any other prescribed medication known to influence bone metabolism. (nih.gov)
We draw upon an ESRC funded study into the use of health technologies in women's midlife, in order to demonstrate how empirical research can illuminate the links between screening for osteoporosis and the recommendation and subsequent decision by women to use therapies such as hormone replacement therapy (HRT).The paper explores the centrality of bone densitometry in decision-making about potential risk. (socresonline.org.uk)
The best treatment for these symptoms is postmenopausal hormone therapy. (ucalgary.ca)
Recent studies suggest that the way postmenopausal hormone replacement therapy is administered may be an important consideration when evaluating this risk. (ucalgary.ca)
She is looking at whether the route of administration of hormone replacement therapy changes a postmenopausal person's risk of cardiovascular disease. (ucalgary.ca)
Gulamhusein hopes to recruit individuals between the ages of 46 and 60 who have completed the menopausal transition and are taking any kind of postmenopausal hormone therapy. (ucalgary.ca)
The effects of adjuvant chemotherapy on the breast cancer disease seem to be as good for pre and postmenopausal patients, at least for hormone receptor negative patients. (diva-portal.org)
Hormone replacement therapy (HRT) exists as one of very few treatment options, but the risks and benefits of HRT is variable and depends on age, individual health status, dose and type of HRT. (eurekalert.org)
We included women aged 50 to 70 years, and excluded women on hormone therapy or missing data. (medscape.com)
[ 9-11 ] Estrogen deficiency can lead to sleep instability, and hormone therapy has been found to correct sleep disorders in some postmenopausal women. (medscape.com)

Prolia (denosumab) is a monoclonal antibody used to treat bone loss ( osteoporosis ) in women who are at high risk for bone fracture after menopause . (rxlist.com)
Prolia is usually used in women after menopause. (rxlist.com)
Susan Ruth Davis, PhD, president of the International Menopause Society, which led the international task force that issued the statement, said the consensus should put clinicians at ease in prescribing testosterone for postmenopausal hypoactive sexual desire dysfunction (HSDD) but not other conditions. (medscape.com)
Arimidex is used mainly in women after menopause . (rxlist.com)
Osteoporosis, a condition associated with weak bones and an increased risk for fracture, is common in women after menopause. (medscape.com)
The researchers compared a control group of 30 women who received no treatment with a group of nine healthy women in early menopause (ages 47 to 60) who knowingly received the testosterone spray on their skin. (sciencedaily.com)
Postmenopausal confusion, also commonly referred to as postmenopausal brain fog, is a group of symptoms of menopause in which women report problems with cognition at a higher frequency during postmenopause than before. (wikipedia.org)
Although much of the literature references women, it is important to understand that all people who undergo menopause, including those who do not self-identify as women, may experience symptoms of postmenopausal confusion. (wikipedia.org)
Research on menopause as a whole declined with the end of the Women's Health Initiative (WHI) studies, but research on the treatment of symptoms associated with menopause-especially the treatment of cognitive decline-continues. (wikipedia.org)
As of 2019, SWAN indicated, "Approximately 60% of midlife women report problems with memory during the [menopause transition], yet studies of measured cognitive performance during the transition are rare. (wikipedia.org)
Menopause is a natural decline in the ovarian function of women who reach the age between 45 and 54 years. (wikipedia.org)
We evaluated the development of hypertension in women after menopause. (biomedcentral.com)
Women who had used OC for 30 months or more had a significantly greater prevalence of hypertension after menopause than those who had never taken OC. (biomedcentral.com)
The risk of hypertension increases rapidly during menopause, which is a time when women undergo hormonal changes. (biomedcentral.com)
An epidemiological study has shown that the prevalence of hypertension in men is higher than in women during the young adulthood period, while that in women increases significantly after menopause [ 9 ]. (biomedcentral.com)
Therefore, it is necessary to identify factors influencing the development of hypertension in women after menopause. (biomedcentral.com)
However, in this study, since there was no distinction between whether hypertension occurred before or after menopause and because it is not known whether hypertension or OC use came first, it is difficult to determine from this prior study whether using OC during the fertile years increases the risk of postmenopausal hypertension. (biomedcentral.com)
Women experience the most bone loss during the first few years after menopause , and they continue to lose bone from this point on. (everydayhealth.com)
Newswise - Women who have gone through menopause and who have been using a vaginal form of estrogen therapy do not have a higher risk of cardiovascular disease and cancer than women who have not been using any type of estrogen. (newswise.com)
This study, the first to examine potential adverse health effects in users of vaginal estrogen compared with non-users, suggests that vaginal estrogen therapy is a safe treatment for genitourinary symptoms such as burning, discomfort, and pain during intercourse associated with menopause. (newswise.com)
There was a significant difference between premenopausal and postmenopausal urinary D-Pyr showing a higher value of D-Pyr during menopause. (annals.edu.sg)
Midlife women experiencing or entering menopause are implicated in debates about 'the expanding elderly', debates which sociologists argue, focus upon representations of them as primarily menopausal bodies: emotional, unstable and at risk of being 'out of control,' ( Lupton 1998 ). (socresonline.org.uk)
It tends to affect men after age 40 and women after menopause, when they lose the protective effects of estrogen. (arthritis.org)
It's critical that we better understand how female-specific experiences, such as pregnancy and menopause, may impact cardiovascular health, especially given the fact that cardiovascular disease is still the leading cause of premature death for Canadian women. (ucalgary.ca)
1. For treatment of moderate to severe vasomotor symptoms and/or moderate to severe symptoms of vulvar and vaginal atrophy due to menopause: The lowest effective dose should be administered. (centerwatch.com)
The lack of estrogen, a natural consequence of menopause, places women at risk of osteoporosis as they age. (buffalo.edu)
The study, "Association Between Osteoporosis Treatment and Severe Periodontitis in Postmenopausal Women," was led by Johelle de S. Passos-Soares, PhD, at the Federal University of Bahia in Brazil, and published in the July issue of Vol. 24 of "Menopause: The Journal of the North American Menopause Society. (buffalo.edu)
In human females, the steep decline in estrogen levels after menopause can often lead to a host of health concerns, including weight gain, cardiometabolic disease, osteoporosis, gastrointestinal disorders and cognitive decline. (eurekalert.org)
CBD is already being used by many women to deal with symptoms of menopause and postmenopause," Roopchand said. (eurekalert.org)
With the onset of menopause, bone loss in women increases considerably: in the first 5-10 years the loss is 25-30% of trabecular bone and 10-15% of cortical bone. (who.int)
Type I tumors are more common, are usually estrogen -responsive, and are usually diagnosed in obese women and at younger ages (perimenopause or early in menopause). (msdmanuals.com)

METHODS: 107 women participated in a double blind placebo controlled trial to evaluate the effect of 50 mg testosterone propionate intramuscularly every two weeks for one year. (bmj.com)
METHODS: A randomized controlled trial was conducted at 40 US clinical centers from 1993 to 2005, including 48,835 postmenopausal women aged 50 to 79 years. (healthpartners.com)
Many of the treatment methods require surgery or specific therapies. (medscape.com)
Closed treatment methods are indicated for stable fractures. (medscape.com)

THOUSAND OAKS, Calif. , April 15, 2019 /PRNewswire/ -- Amgen (NASDAQ: AMGN) today announced that EVENITY™ (romosozumab-aqqg) is now available for shipment to wholesalers in the U.S. EVENITY was approved by the U.S. Food and Drug Administration ( FDA ) on April 9, 2019 , for the treatment of osteoporosis in postmenopausal women at high risk for fracture. (amgen.com)
The approval of EVENITY in the U.S. helps address an unmet need by providing another option for postmenopausal women at high risk for fracture who need to build bone rapidly within 12 months and to reduce the risk of a first or subsequent fracture. (amgen.com)

Postmenopausal osteoporosis is considered a serious public health concern due to its high prevalence worldwide," it added. (creakyjoints.org)
The National Health and Nutrition Examination Survey from 2013 to 2014 reported that 16.5 % of women aged 50 years or older in the US have osteoporosis (vs only 5% of men of a similar age), with an increasing prevalence with increasing age. (medscape.com)
This study identified an association between past OC use and an increased prevalence of hypertension in postmenopausal women. (biomedcentral.com)
Hypertension places the largest health burden on people over 50 years old worldwide of any disease [ 4 ] and, in particular, the prevalence of hypertension in women is increasing faster than that in men [ 5 ]. (biomedcentral.com)
A previous study examined the relationship between OCs use and blood pressure and the prevalence of hypertension in aged 35-55 years' Korean women [ 11 ]. (biomedcentral.com)
As the vitamin D status of Algerian postmenopausal women was poorly described, this cross-sectional study investigated the prevalence of low vitamin D status in a sample population. (hindawi.com)
However, data obtained from various populations of community-living postmenopausal women with or without osteoporosis highlight a wide disparity of prevalence rates of 25(OH)D concentration ≤ 20 ng/mL depending on the considered geographical areas [ 7 , 8 ]. (hindawi.com)
For instance, in a European study involving more than 8500 postmenopausal women, the prevalence of 25(OH)D deficiency reached 32.1% when considering the cutoff value of 20 ng/mL [ 9 ], while in Indian, Chinese, and US populations of postmenopausal women, the estimated prevalence rates were 53.3%, 72.1%, and 53%, respectively [ 10 - 12 ]. (hindawi.com)
BUFFALO, N.Y. - Treatment for osteoporosis may also help prevent gum disease, according to new University at Buffalo research that examined the prevalence of periodontitis in postmenopausal women. (buffalo.edu)
Fluoride has been shown to decrease the prevalence of dental caries and, under certain conditions, has been used for the treatment of osteoporosis. (cdc.gov)
Increasing trends in obesity prevalence among black women could be contributing to increasing incidence of breast cancer. (cdc.gov)
ABSTRACT The study aimed to determine hospital-based prevalence of vertebral fractures in post- menopausal Saudi Arabian women. (who.int)

Existing evidence clearly shows that testosterone is beneficial in the treatment of sexual desire dysfunction in postmenopausal women, but not for any other conditions or symptoms, the authors conclude. (medscape.com)
It is not an effective treatment for menopausal symptoms, including hot flushes, night sweats, anxiety, low mood, sleep disruptions," said Davis, who is also a professor of women's health and director of the Women's Health Research Program at Monash University, in Melbourne, Australia. (medscape.com)
Jan. 17, 2019 Mindfulness may be associated with fewer menopausal symptoms for women, according to a new study. (sciencedaily.com)
Postmenopausal confusion is often manifested through the following cognitive symptoms: memory problems, forgetfulness, and poor concentration. (wikipedia.org)
Efficacy for vasomotor symptoms was assessed during the first 12 weeks of treatment in a subset of symptomatic women (n=241) who had at least seven moderate to severe hot flushes daily or at least 50 moderate to severe hot flushes during the week before randomization. (centerwatch.com)
The untreated estrogen-deficient mice developed symptoms that resembled those of postmenopausal human females, such as metabolic dysfunction, evidence of inflammation, lower bone density, and lower levels of beneficial gut bacteria. (eurekalert.org)
radiotherapy, surgery) and clinically stable off steroids for management of symptoms for at least 4 weeks prior to study treatment initiation. (who.int)

Miacalcin injection is indicated for the treatment of postmenopausal osteoporosis in women greater than 5 years postmenopause. (drugs.com)
Confusion which is otherwise unexplained and coincides with the onset of postmenopause may be postmenopausal confusion. (wikipedia.org)
Moreover, women who gained weight in early postmenopause increased their risk even if they were a normal weight at the start of the study, Neuhouser said. (feelgoodnatural.com)

Changes in biomarkers levels from gingival crevicular fluid in pre- and postmenopausal women undergoing orthodontic treatment : A systematic review. (bvsalud.org)
This study aimed to verify whether there is a difference in biomarker levels in the gingival crevicular fluid between premenopausal and postmenopausal women undergoing orthodontic treatment . (bvsalud.org)
As eligibility criteria, prospective or retrospective observational studies evaluating women undergoing orthodontic treatment (P), comparing postmenopausal (E) and premenopausal (C) women , and analyzing differences in gingival crevicular fluid biomarkers (O) were included. (bvsalud.org)
Therefore, further studies must include other types of bone and inflammatory biomarkers in female patients who are pre- or postmenopausal and undergoing orthodontic treatment . (bvsalud.org)

I'm very excited for a new treatment option for myself, as well as the thousands of other women who may benefit from a treatment that will build bone and slow bone loss. (amgen.com)
For some women following these strategies is just not enough to prevent bone loss and/or broken bones. (nysopep.org)
You can't restore your bone density to what it was at its peak, but you can stimulate bone formation and slow age-related bone loss by engaging in weight-bearing and muscle-building exercises, following a healthy diet, and taking one of the drugs approved for the treatment of osteoporosis. (everydayhealth.com)
Hence D-Pyr may be useful for the monitoring of hormonal treatment of postmenopausal bone loss. (annals.edu.sg)
We conducted an effectiveness meta-analysis to determine the efficacy of fluoride therapy on bone loss, vertebral and nonvertebral fractures and side effects in postmenopausal women. (fluoridealert.org)
The researchers found that women receiving osteoporosis treatment had less periodontal probing depth and clinical attachment loss - the amount of space between teeth and surrounding tissue due to bone loss - and less gum bleeding than those who did not receive therapy. (buffalo.edu)
Prolia was later approved to treat men with osteoporosis, glucocorticoid induced osteoporosis, bone loss in men receiving androgen deprivation therapy for prostate cancer and in women receiving aromatase inhibitor therapy for breast cancer. (medlineplus.gov)

Data on the effect of both treatments on fracture risk were taken from the Cochrane Database of Systematic Reviews. (unboundmedicine.com)
Two-hundred fifty-five physically inactive postmenopausal women (55-75 years) with 10-year major osteoporotic fracture risk (3%-35%) participated in this 18-month study. (frontiersin.org)
Additional data offered new insights into neurological factors contributing to fracture risk, the impact of the COVID pandemic and subsequent public health lockdowns on the existing treatment and care gaps, and the use of artificial intelligence in osteoporosis screening. (ucb.com)
Why Increased Fracture Risk in Postmenopausal Women? (medscape.com)

Androgens as adjuvant treatment in postmenopausal female patients with rheumatoid arthritis. (bmj.com)
For adjuvant treatment of early breast cancer in postmenopausal women, the optimal duration of therapy is unknown. (rxlist.com)
The aim of this study was to follow HRQOL in postmenopausal women (55−80 years) with breast cancer receiving adjuvant treatment after surgery, until five years post-treatment, and compare with a general population. (diva-portal.org)
The patient sample included 150 women (adjuvant CT n = 75 and RT n = 75) and two reference samples from the Swedish SF- 36 norm database. (diva-portal.org)
Conclusion: Postmenopausal women (55−80 years) seem to successfully manage the effects of adjuvant treatment on HRQOL. (diva-portal.org)
Conclusion: Expression of ERh is an independent marker for favorable prognosis after adjuvant tamoxifen treatment in ERa-negative breast cancer patients and involves a gene expression program distinct from ERa. (lu.se)
These results may be highly clinically significant, because in the United States alone, f10,000 women are diagnosed annually with ERa-negative/ERh-positive breast carcinoma and may benefit from adjuvant tamoxifen. (lu.se)

This study will compare the effects of different amounts of aerobic exercise on heart and lung (cardiorespiratory) fitness in post-menopausal women who completed treatment for early-stage breast cancer. (mskcc.org)
Another small RCT involving post-menopausal women found no significant difference between calcium plus vitamin D 3 and placebo in hip fractures after two years. (aafp.org)
However, another systematic review and two subsequent RCTs involving post-menopausal women found no significant difference in vertebral fractures. (aafp.org)
Post-menopausal women have better memory after daily treatment with a testosterone spray for six months, a new preliminary study finds. (sciencedaily.com)
Halford J, Walker KA, Duhig J: A review of histological outcomes from peri-menopausal and post-menopausal women with a cytological report of possible high grade abnormality: an alternative management strategy for these women. (karger.com)
1. Adult females (pre-/peri-/ and post-menopausal), and adult males. (who.int)

Miacalcin injection is indicated for the treatment of symptomatic Paget's disease of bone in patients with moderate to severe disease characterized by polyostotic involvement with elevated serum alkaline phosphatase and urinary hydroxyproline excretion. (drugs.com)
Treatment of Paget's disease of bone: a single 5 mg infusion. (nih.gov)

Case reports: Female, 57 years (yrs) old, presented with hirsutism (Ferriman Galwey score, FGS 18), weight gain, type 2 diabetes mellitus (DM2), hypertension, hyperlipidemia and obesity (BMI 38.5 kg/m 2 ). (endocrine-abstracts.org)
Obesity is known to increase estrogens in the postmenopausal women because estrogen is made by fat tissue," Neuhouser said. (feelgoodnatural.com)
In North Algeria, the abundant sunlight appears insufficient to fully offset hypovitaminosis D risk factors in postmenopausal women, especially obesity and veiling. (hindawi.com)
To investigate the relationship between obesity and sleep architecture in postmenopausal women. (medscape.com)
In postmenopausal women, high BMI and abdominal obesity are sources of sleep disturbances, decreasing deep sleep, and sleep efficiency, while increasing the risk of obstructive sleep apnea. (medscape.com)

One large RCT involving postmenopausal women with osteoporosis found that raloxifene reduced vertebral fractures compared with placebo, but no significant difference was found in nonvertebral fractures. (aafp.org)
One systematic review involving postmenopausal women found that etidronate reduced vertebral fractures compared with control (placebo, calcium, or calcium plus vitamin D) over two years but found no significant difference in nonvertebral fractures. (aafp.org)
One systematic review found limited evidence from two small RCTs involving postmenopausal women that calcitriol reduced vertebral fractures after three years compared with placebo. (aafp.org)
One systematic review involving postmenopausal women found that calcitonin reduced vertebral fractures compared with placebo one to five years after treatment but found no significant difference between calcitonin and placebo in nonvertebral fractures. (aafp.org)
One small RCT involving postmenopausal women found no significant difference between a two-year back strengthening exercise program and usual care in vertebral fractures over 10 years. (aafp.org)
Women who are aged 70 or older, and those who have had significant height loss, should also get radiography of the spine to look for vertebral fractures. (medscape.com)
To assess the effect of fluoride treatment on the fracture rate in osteoporosis, we conducted a four-year prospective clinical trial in 202 postmenopausal women with osteoporosis and vertebral fractures who were randomly assigned to receive sodium fluoride (75 mg per day) or placebo. (elsevierpure.com)
In only 37.8% of the radiographs with fractures was a vertebral fracture highlighted in the radiologist's report, and only 13.2% of the women with vertebral fractures were on antiresorptive therapy for osteoporosis. (who.int)

Randomized trials and other studies have shown that women who take estrogen therapy in the form of a pill may have an increased risk of blood clots, stroke and if the estrogen is used together with progestogen pills, invasive breast cancer. (newswise.com)
To counter these effects, some women are prescribed estrogen therapy along with supplements of calcium and vitamin D. (buffalo.edu)
Of the 356 women who were diagnosed with osteoporosis, 113 chose to receive estrogen therapy. (buffalo.edu)
They were divided into two categories: women who received estrogen therapy for at least six months and those who never received treatment. (buffalo.edu)

For this reason, estrogen should not be used for the express purpose of preventing cardiovascular disease, but it may be appropriate for the short-term treatment of moderate-to-severe hot flashes or night sweats among recently menopausal women. (nih.gov)
The WHI is a major, 15-year research program designed to address the most frequent causes of death, disability, and poor quality of life in postmenopausal women: cardiovascular disease, cancer, and osteoporosis. (nih.gov)
Cardiovascular disease is the leading cause of premature death in women in Canada, claiming the life of a woman every 20 minutes. (ucalgary.ca)

Postmenopausal women with self-reported severe osteoporosis, defined as having suffered at least one osteoporotic fracture and reporting a T-score of ≤− 2.5, were asked to evaluate their health status, osteoporosis management, and disease-related physical, emotional, and financial burden. (dovepress.com)
Furthermore, older age, low bone density, a previous history of fracture, a family history of hip fracture, smoking, and excessive alcohol intake increase the risk for an osteoporotic fracture in a postmenopausal woman. (medscape.com)

Patients attached the greatest value to a treatment that would decrease probability of future fractures, followed by increase in bone density, safety, and mode and frequency of administration. (dovepress.com)
Patients reported valuing treatment efficacy, measured through reduction in future fractures and increase in bone density, and safety, as key treatment attributes. (dovepress.com)
When asked about treatment preferences, patients valued a treatment that would decrease probability of future fractures, followed by increase in bone density, safety, mode of administration, and frequency of administration. (dovepress.com)
Data further demonstrated that patients at high risk of fracture may benefit the most from treatment with romosozumab first, followed by an antiresorptive. (ucb.com)
Miacalcin injection should be used only in patients who do not respond to alternative treatments or for whom such treatments are not suitable (e.g., patients for whom other therapies are contraindicated or for patients who are intolerant or unwilling to use other therapies). (drugs.com)
Over 20% of patients taking Nirmatrelvir-ritonavir therapy, commonly known as Paxlovid, suffer from the rebound, compared to less than the 2% chance seen in other treatment groups, a Harvard Medical School study revealed. (medicaldaily.com)
The Arthritis Foundation is mobilizing patients and their families to engage in studies comparing the effectiveness of treatments for juvenile arthritis and funding research for more options. (arthritis.org)
A urea breath test was performed on all patients 45 days after beginning treatment. (naturalmedicinejournal.com)
By advancing our understanding of how this treatment can impact oral health, we can better work to improve the bone health and quality of life of female patients. (buffalo.edu)
Cancer treatment of the elderly patients is an increasingly important concern since the risk for developing breast cancer increases with age. (diva-portal.org)
Five years after completion of treatment, the patient sample experienced better HRQOL than the reference sample in all domains, supporting our hypothesis that the impact on HRQOL would have been resolved over time for these patients. (diva-portal.org)
HA565 trade name] is indicated as a pharmacokinetic enhancer for protease inhibitors when these are used in combination therapy with other antiretroviral agents for the treatment of HIV-1 infected patients. (who.int)
Saquinavir 1000 mg twice daily with ritonavir 100 mg twice daily in antiretroviral treatment (ART)- experienced patients. (who.int)
Initiate treatment with saquinavir 500 mg twice daily with ritonavir 100 mg twice daily for the first 7 days, then saquinavir 1000 mg twice daily with ritonavir 100 mg twice daily in ART- naïve patients. (who.int)
Tipranavir with ritonavir should not be used in treatment-naïve patients. (who.int)
Patients should not stop Prolia treatment without first consulting your health care professional, as stopping may worsen your bone condition. (medlineplus.gov)

A validated Markov microsimulation model with a Belgian payer's perspective estimated the cost per quality-adjusted life-year (QALY) of a 3-year strontium ranelate treatment compared with no treatment and with the bisphosphonate risedronate. (unboundmedicine.com)
looked at 3D modelling from hip DXA scans in postmenopausal women with osteoporosis who received oral bisphosphonate therapy for ≥3 years and ALN for ≥1 year prior to screening, and were randomized to ROMO or a comparator (STRUCTURE: teriparatide [TPTD]) for 12 months. (ucb.com)
Psychometric evaluation of the Osteoporosis Patient Treatment Satisfaction Questionnaire (OPSAT-Q TM ), a novel measure to assess satisfaction with bisphosphonate treatment in postmenopausal women. (bvsalud.org)

The results of this study suggest that strontium ranelate is a cost-effective strategy, in a Belgian setting, for the treatment of postmenopausal osteoporotic women aged over 75 years. (unboundmedicine.com)
The objectives of this study were to elicit self-reported health status, quantify osteoporosis-related burden, and understand preferences for treatment attributes among postmenopausal women with severe osteoporosis in Greece. (dovepress.com)
Our study revealed that osteoporosis placed a considerable burden on QoL for postmenopausal women with severe osteoporosis in Greece. (dovepress.com)
This study aimed to describe patient-reported health status and quality of life in postmenopausal women with severe osteoporosis in Greece, and to understand patient preferences for osteoporosis therapies. (dovepress.com)
The women were between the ages of 50 and 70 when they were recruited, and they were followed up over the decade of the full study. (medicalnewstoday.com)
In June, Medical News Today reported on a study in which researchers discovered a way to boost bone-forming cells , paving the way for new treatments for osteoporosis. (medicalnewstoday.com)
For this reason, females are the primary focus of this study. (frontiersin.org)
The 3,591 postmenopausal women in the study who were given placebo treatment were five times likelier to experience fractures than the 3,589 administered romosozumab, an antibody given as an injection which inhibits a protein called sclerostin and increases bone density and formation. (creakyjoints.org)
The following organizations helped finance this study: the National Health and Medical Research Council of Australia, the Royal Australasian College of Physicians Research and Education Foundation (Vincent Fairfax Family Foundation fellowship) and FemPharm in Australia, which makes the testosterone spray for women. (sciencedaily.com)
Treatment with a new class of drugs, called senolytics, in donors improved the physical fitness of the recipients, a new study has shown. (medicaldaily.com)
The study indicates the possibility of using heated yoga as a viable treatment option for depression, as 44% of the participants who took up the sessions indicated signs of remission. (medicaldaily.com)
The study suggests the possibility of using trans-vaccenic acid found in red meat and dairy products as a nutritional supplement to complement treatments for cancer. (medicaldaily.com)
This study aimed to evaluate the association between past use of OC and development of hypertension in postmenopausal women. (biomedcentral.com)
This was a cross-sectional study conducted using data from the Fifth Korea National Health and Nutrition Examination Survey of postmenopausal women. (biomedcentral.com)
A cross-sectional study conducted in Australia reported that past use of OC in postmenopausal women was not associated with postmenopausal development of hypertension [ 10 ]. (biomedcentral.com)
This study used data from the Korea National Health and Nutrition Examination Survey (KNHANES) conducted from 2010 to 2012 to analyze the association between past use of OC and the occurrence of postmenopausal hypertension. (biomedcentral.com)
A third study reported that there was a higher expression of IL17-A in the postmenopausal group. (bvsalud.org)
Having osteoporosis reduces a person's life expectancy, a study found, but just how much depended on the age at which treatment was started. (everydayhealth.com)
This study was conducted to compare the correlation between Pap smear and colposcopic biopsy findings in premenopausal and postmenopausal women. (karger.com)
In February 2006, WHI researchers reported that among the women in the estrogen-alone trial who were 50-59 years of age at study entry, women in the estrogen group had a non-significant trend towards lower rates of heart attacks compared to the placebo group, and significantly fewer women in the estrogen group required procedures to re-open clogged arteries. (nih.gov)
The findings of the present study confirmed the ability of dried plum in improving BMD in postmenopausal women in part due to suppressing the rate of bone turnover. (nih.gov)
Study shows higher healing rate using unique cell-based therapy in chronic venous leg ulcers - Treating chronic venous leg ulcers with a topical spray containing a unique living human cell formula provides a 52 percent greater likelihood of wound closure than treatment with compression bandages only. (healthnewstrack.com)
THURSDAY, June 11, 2015 (HealthDay News) - A study of more than 67,000 women suggests that those who are obese and postmenopausal may face significantly higher odds for breast cancer compared with slimmer women. (feelgoodnatural.com)
The risk for breast cancer among the most obese women in the study was up to 58 percent higher than for normal-weight women. (feelgoodnatural.com)
In this study, the researchers said the most obese women had a body mass index (a measure of body fat) of 35 or higher. (feelgoodnatural.com)
Women who lost weight during the study reduced their risk for breast cancer, Neuhouser said. (feelgoodnatural.com)
For the study, Neuhouser and her colleagues collected data on more than 67,000 postmenopausal women who took part in a study called the Women's Health Initiative from 1993 to 1998. (feelgoodnatural.com)
Women who gained more than 5 percent of their body weight over the years of the study also had an increased risk for breast cancer, according to the researchers. (feelgoodnatural.com)
A new study will help women and their health-care providers choose the care that is right for them. (ucalgary.ca)
By enrolling in this study, participants will help us advance our knowledge about postmenopausal individuals' cardiovascular health and ultimately help other women make decisions about their own health and what is right for them. (ucalgary.ca)
The study is designed with the flexibility to open new treatment arms as new treatments become available, close existing treatment arms that demonstrate minimal clinical activity or unacceptable toxicity, or modify the patient population. (uclahealth.org)
Data are from 2,805 postmenopausal women enrolled in the HOPE Study. (centerwatch.com)
The study revealed that women over the age of 50 treated with estrogen for osteoporosis - a condition in which the bones become weak and brittle from tissue loss - are 44 percent less likely to have severe periodontitis than women who did not receive the treatment. (buffalo.edu)
A Rutgers study points to cannabidiol (CBD), a major component of hemp and medical marijuana used to treat conditions such as chronic pain, inflammation, migraines, epilepsy, autoimmune diseases, depression, and anxiety, as a possible treatment for postmenopausal women, whose ovaries no longer make estrogen. (eurekalert.org)
Two hundred and twenty women with postmenopausal osteoporosis were included in the study. (who.int)
The Postmenopausal Women's Alcohol Study was a controlled feeding study to test the effects of low to moderate alcohol intake on potential risk factors for breast cancer including serum and urinary levels of hormones and other biomarkers. (cdc.gov)
One hundred seven postmenopausal women from the Ambulatory of Integrative Treatment for Female Sleep Disorders were invited by telephone to participate in this study. (medscape.com)
2. Radiotherapy within 2 weeks prior to study treatment initiation. (who.int)
3. Major surgery or significant traumatic injury within 4 weeks of the first dose of study treatment. (who.int)
When FDA first approved Prolia, we required the manufacturer, Amgen, to conduct a long-term safety study in women with postmenopausal osteoporosis and men with osteoporosis. (medlineplus.gov)

From diagnosis to treatment, our experts provide the care and support you need, when you need it. (mskcc.org)
The contents of this website are for informational purposes only and do not constitute medical advice.CreakyJoints.org is not intended to be a substitute for professional medical advice, diagnosis, or treatment. (creakyjoints.org)
The actress Sally Field recently described her struggles with postmenopausal osteoporosis - she was given the diagnosis when she was 60 years old despite being physically active and engaging in activities such as biking, hiking, and yoga. (medscape.com)
The research examined nearly 500 postmenopausal women who received service at an osteoporosis diagnosis center in Brazil. (buffalo.edu)
The early diagnosis and treatment of them is important in improving postmenopausal women's quality of life. (medscape.com)

ARIMIDEX is indicated for the treatment of advanced breast cancer in postmenopausal women with disease progression following tamoxifen therapy. (rxlist.com)
Participants in the control or experimental arms who experience unacceptable toxicity, disease progression as determined by the investigator according to RECIST v1.1, or loss of clinical benefit as determined by the investigator during Stage 1 will be given the option of receiving a different treatment combination during Stage 2, provided they meet eligibility criteria and a treatment arm is open for enrollment. (uclahealth.org)

With the approval of EVENITY, we have a new treatment option in our tool chest to find the appropriate treatment for each individual based on her clinical risk factors, goals of treatment and individual preferences. (amgen.com)
studies that showed greater BMD gains, reduced new vertebral fracture incidence and lower incidence of clinical, non-vertebral and hip fractures with ROMO/DMAB treatment, and significant improved bone microarchitecture with ROMO/ALN treatment, respectively. (ucb.com)
In postmenopausal women with osteoporosis, Prolia reduces the incidence of vertebral, nonvertebral, and hip fractures [see Clinical Studies ]. (rxlist.com)
In clinical practice, it is common that elderly women are offered less chemotherapy, because of the unsubstantiated belief that they will experience a larger number and more severe adverse effects as well as poor functional outcomes and significant decrements in health related quality of life (HRQOL). (diva-portal.org)
Notably, clinical studies indicate that HRT use in women over 60 leads to greater risk of heart disease, stroke, blood clots and cancer. (eurekalert.org)

FDA Approves New Injectable Osteoporosis Treatment for Postmenopausal Women - The U.S. Food and Drug Administration approved Prolia, an injectable treatment for postmenopausal women with osteoporosis who are at high risk for fractures. (healthnewstrack.com)

OBJECTIVE: To examine the possible beneficial effect of androgens in postmenopausal women with active rheumatoid arthritis. (bmj.com)
HSDD is the only condition for which testosterone treatment has been proven to be beneficial to women. (medscape.com)
However, the consensus statement underscores that the evidence only shows that testosterone treatment is beneficial for women who are postmenopausal. (medscape.com)

Two systematic reviews involving postmenopausal women found that alendronate reduced vertebral and nonvertebral fractures compared with placebo after one to four years. (aafp.org)
Alendronate sodium tablets, USP are indicated for the treatment of osteoporosis in postmenopausal women. (nih.gov)
In postmenopausal women, alendronate sodium tablets, USP increases bone mass and reduces the incidence of fractures, including those of the hip and spine (vertebral compression fractures). (nih.gov)

Arimidex ( anastrozole ) is a non-steroidal aromatase inhibitor used to treat breast cancer in postmenopausal women. (rxlist.com)
Among women with an intact uterus, the risks of stroke, invasive breast cancer, colorectal cancer, endometrial cancer and pulmonary embolism/deep vein thrombosis were not significantly different between vaginal estrogen users and nonusers. (newswise.com)
During an average 13 years of follow-up, more than 3,300 women developed breast cancer. (feelgoodnatural.com)
The researchers found that very obese women were at risk for estrogen- and progesterone-driven breast cancer, but not for other types. (feelgoodnatural.com)
Among women who were already overweight or obese, Neuhouser's team found no change in risk for breast cancer whether they lost or gained weight over the 13 years of follow-up. (feelgoodnatural.com)
4. For treatment of breast cancer, for palliation only: 10 mg three times daily for a period of at least three months. (centerwatch.com)
Context: Low overnight urinary melatonin metabolite concentrations have been associated with increased risk for breast cancer among postmenopausal women. (cdc.gov)
Despite improvements in early detection and treatment for breast cancer, black women continue to have the highest breast cancer mortality rate. (cdc.gov)
Since 1975, black women have had lower breast cancer incidence compared to white women, but rates have recently converged, in part because of increasing breast cancer incidence in black women. (cdc.gov)
In-depth analyses of population-based data indicated that breast cancer incidence is equal for black and white women in part because of incidence increasing among black women, particularly among those aged 60-79 years. (cdc.gov)
Breast cancer mortality continues to be higher among black women compared with white women, with death rates decreasing faster among white women. (cdc.gov)
50 years, breast cancer death rates are decreasing at the same rate among black and white women. (cdc.gov)
Measures to ensure access to quality care and the best-available treatments for all women diagnosed with breast cancer can help address these racial disparities. (cdc.gov)
Breast cancer continues to be the most commonly diagnosed cancer and the second leading cause of cancer deaths among U.S. women ( 1 ). (cdc.gov)
Compared with white women, black women historically have had lower rates of breast cancer incidence and, beginning in the 1980s, higher death rates ( 1 ). (cdc.gov)
Overall rates of breast cancer incidence were similar, but death rates remained higher for black women compared with white women. (cdc.gov)
During 1999-2013, breast cancer incidence decreased among white women but increased slightly among black women resulting in a similar average incidence at the end of the period. (cdc.gov)
Breast cancer incidence trends differed by race and age, particularly from 1999 to 2004-2005, when rates decreased only among white women aged ≥50 years. (cdc.gov)
When combined with population-based approaches to increase knowledge of family history of cancer, increase physical activity, promote a healthy diet to maintain a healthy bodyweight, and increase screening for breast cancer, targeted treatment interventions could reduce racial disparities in breast cancer. (cdc.gov)
Swedish Research Council frequently prescribed drug for treatment of breast cancer. (lu.se)
It is used in the treatment of metastatic or locally advanced breast cancer in postmenopausal women. (bvsalud.org)

To estimate the cost-effectiveness of strontium ranelate in the treatment of postmenopausal osteoporotic women aged over 75 years. (unboundmedicine.com)
Strontium ranelate was dominant (i.e. more effective and less costly) versus risedronate for women with osteoporosis aged over 75 years and for women with PVF aged 80 years. (unboundmedicine.com)
The cost per QALY gained of strontium ranelate compared with risedronate at 75 years of age was euro 11,435 for women with PVF. (unboundmedicine.com)
One systematic review involving postmenopausal women found that compared with control (i.e, placebo, calcium, or calcium plus vitamin D) risedronate reduced vertebral and nonvertebral fractures after four years. (aafp.org)
Calcium Plus Vitamin D . One large RCT involving women 69 to 106 years of age living in nursing homes found that calcium plus vitamin D 3 reduced hip fractures and all nonvertebral fractures after 18 months to three years compared with placebo. (aafp.org)
One smaller RCT involving women and men 65 years or older found that calcium plus vitamin D 3 reduced nonvertebral fractures after three years compared with placebo but found no significant difference in hip fractures. (aafp.org)
One systematic review involving postmenopausal women found no significant difference between calcium supplementation and placebo in vertebral or nonvertebral fractures after one and one half to four years. (aafp.org)
One large RCT involving postmenopausal women and two large RCTs involving postmenopausal women and older men provided no evidence of a difference between vitamin D 3 and placebo in hip, vertebral, and nonvertebral fractures after two to five years. (aafp.org)
For example, the risk for osteoporosis of the hip increases from about 7% in women 50-59 years of age to about 35% in those aged 80 years or older . (medscape.com)
Although the use of calcium and vitamin D supplementation in postmenopausal women is still debated, the Institute of Medicine recommends that women 51-70 years of age take 1000-1200 mg of calcium and 400-600 IU of vitamin D daily, and that those older than 70 years take 1000-1200 mg of calcium and 400-800 IU of vitamin D daily. (medscape.com)
There is little evidence as to whether the use of oral contraceptives(OC) during the fertile years affects the development of postmenopausal hypertension. (biomedcentral.com)
There was no suggestion of cardiovascular benefit in women who were 60 years or older. (nih.gov)
Although takotsubo cardiomyopathy most often affects females aged 62-76 years , males with the condition are less likely to have a positive outlook. (medicalnewstoday.com)
All the 336 selected women ≥ 45 years from Douera were interviewed to get anthropometric and lifestyle data, reproductive and medical history, medications, and calcium/vitamin D intakes. (hindawi.com)
The increase in lumbar spine bone mineral density (BMD) was found to be higher in the treatment group than in the control group with a WMD 8.1% (95% CI: 7.15, 9.09) after 2 years of treatment and 16.1% (95% CI: 14.65, 17.5) after 4 years. (fluoridealert.org)
Most cases are diagnosed in women aged 45 to 74 years. (msdmanuals.com)
With the average life expectancy close to 80 years, women may spend one-third or more of their lives in the postmenopausal stage. (medscape.com)
Chest radiographs from consecutive Saudi women over the age of 50 years visiting the emergency room at King Fahd Hospital of the University were evaluated. (who.int)
The mean age of the women was 65.7 (SD 8.5) years. (who.int)
18% were of wrist fractures and more than twice that in females above the age of 50 years. (who.int)

The risks of coronary heart disease, stroke, cancer and pulmonary embolism/deep vein thrombosis for women who had undergone hysterectomies were not significantly different in users of vaginal estrogen compared to nonusers. (newswise.com)
As the condition is significantly more common among females than among males, researchers have considered the role of hormones such as estrogen. (medicalnewstoday.com)
The results showed that at baseline the women in the patient sample experienced significantly higher levels of physical functioning and general health compared to the general population. (diva-portal.org)
Results: Concentration of 6-SMT was not significantly modified by the alcohol treatment after adjustment for body mass index, hours of sleep, daylight hours, and baseline level of 6-SMT. (cdc.gov)

Treatment of postmenopausal osteoporosis when alternative treatments are not suitable. (drugs.com)

Postmenopausal women with osteoporosis who took romosozumab for a year experienced "rapid and large reductions" in risk of fracturing vertebrae compared to placebo, notes research presented in Madrid at the 2017 Annual European Congress of Rheumatology. (creakyjoints.org)
Sixty-six women in the fluoride group and 69 women in the placebo group completed the trial. (elsevierpure.com)
The women were randomly assigned to one of eight treatment groups, receiving either placebo or conjugated estrogens, with or without medroxyprogesterone acetate. (centerwatch.com)

Conclusion: Resolving the origin of androgen excess is important for adequate treatment. (endocrine-abstracts.org)

Association between subjective cognitive complaints and objective measures of performance show a significant impact on health-related quality of life for postmenopausal women. (wikipedia.org)
Therefore, the Persian version of the ECOS-16 is a reliable and valid questionnaire to be used in the evaluation of quality of life in women with postmenopausal osteoporosis. (who.int)
[ 1-3 ] At the postmenopausal stage, sleep disturbances and weight gain are major health concerns, affecting the quality of life. (medscape.com)

So we are proud to communicate additional data supporting romosozumab as a bone forming option for postmenopausal women with severe osteoporosis at high risk of fracture," said Emmanuel Caeymaex, Executive Vice President, Immunology Solutions & Head of US, UCB. (ucb.com)
Postmenopausal women with osteoporosis who took romosozumab for a year experienced "rapid and large reductions" in risk of fracturing vertebrae. (creakyjoints.org)
As a slim, White woman in her sixth decade of life, she certainly had several risk factors for osteoporosis. (medscape.com)
Bone density assessment using DXA is recommended in postmenopausal women who are at increased risk for low bone density and fracture. (medscape.com)
Women have a higher risk of developing dementia compared to men," said Sonia Davison, MD, PhD, the study's lead investigator and a postdoctoral research fellow at Monash University, Melbourne. (sciencedaily.com)
A 2019 literature review identified hypertension and a history of preeclampsia as significant risk factors for the accelerated decline of cognitive function in women during midlife. (wikipedia.org)
In general, the younger a person was, the larger the reduction in life expectancy, with men having a much higher risk of mortality than women. (everydayhealth.com)
We conclude that, although the technological results are open to flexible interpretation, they seem to confirm the 'at risk' status of many of the women. (socresonline.org.uk)
The scan results appear to assume centre-stage in the consultation discussions, leading both women and clinicians to over interpret their significance as an indicator of risk. (socresonline.org.uk)
1.2 The aim of this paper is to explore the role of technology in both the communication of health risks to midlife women and in facilitating their understanding and management of health risk and in particular, the factors behind the elevated status of DEXA scan measurements in decision making. (socresonline.org.uk)
end of menstrual periods) who have a high risk of a fracture or when other osteoporosis treatments did not help or could not be tolerated. (medlineplus.gov)
With increasing life expectancy, oste- of any proven risk factor for osteoporo- ahead without tipping the head up or oporosis is becoming a major worldwide sis apart from all being postmenopausal. (who.int)
BACKGROUND: Prolia is a prescription medicine approved in June 2010 to treat postmenopausal women with osteoporosis at high risk for bone fracture. (medlineplus.gov)
end of menstrual periods) who have an increased risk for fractures (broken bones) or who cannot take or did not respond to other medication treatments for osteoporosis. (medlineplus.gov)

Participants were also asked to rate a series of treatment attributes and state their preference for unlabeled anabolic treatments, based on scenarios describing key treatment characteristics. (dovepress.com)
When asked to select their preferred treatment scenario between two anabolic treatments, 70% of participants opted for the scenario that shared treatment characteristics with romosozumab over a scenario that shared treatment characteristics with teriparatide. (dovepress.com)
The researchers compared the participants' bone density and rate of fractures with those of a group of 120 women who did not have osteoporosis. (medicalnewstoday.com)
Qualified participants (n 160) were randomly assigned to one of the two treatment groups: dried plum (100 g/d) or dried apple (comparative control). (nih.gov)
During Stage 1, participants in each cohort will be randomly assigned to treatment arms. (uclahealth.org)

Postmenopausal women with self-reported severe osteoporosis evaluated their health status, osteoporosis management, and disease-related physical, emotional, and financial burden. (dovepress.com)

Sudden catecholamine surge during nightmare augmented by estrogen deficiency in postmenopausal women may be the underlying mechanism. (scirp.org)

These results offer a potential therapy, where none currently exists, to slow cognitive decline in women. (sciencedaily.com)
Studies have shown "associations between poor sleep quality and cognitive decline" in postmenopausal women as those with insufficient sleep or difficulty falling or staying asleep have reported decreased cognitive performance including "verbal memory, attention, and general cognition. (wikipedia.org)
There is evidence linking depression and cognitive decline in postmenopausal women. (wikipedia.org)

0.001) for all treatment groups (conjugated estrogens alone and conjugated estrogens/medroxyprogesterone acetate treatment groups). (centerwatch.com)

Women with evidence of hyperandrogenism and disordered menses have many other medical issues that must be addressed (eg, PCOS with associated diabetes and hypertension). (medscape.com)

We need to urgently make postmenopausal osteoporosis a women's health priority. (amgen.com)
After slightly more than one year after treatment ended, researchers used computed tomography (CT scan) to measure the level of calcium plaque in the women's coronary arteries. (nih.gov)
Heart attacks are uncommon among younger women, and the more relevant question is about long-term benefit as women grow older," noted Jacques Rossouw, M.D., chief of the NHLBI Women's Health Initiative Branch. (nih.gov)

[ 14 ] There is also evidence that estrogen withdrawal affects fat distribution, leading to an increased proportion of abdominal fat in postmenopausal women. (medscape.com)

In the romosozumab group, fractures occurred in just the first two months of treatment, per a release . (creakyjoints.org)
Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with romosozumab-aqqg injection and each time you refill your prescription. (medlineplus.gov)
Romosozumab-aqqg injection is only approved for treatment of postmenopausal women. (medlineplus.gov)
you should know that romosozumab-aqqg injection may cause osteonecrosis of the jaw (ONJ, a serious condition of the jaw bone), especially if you need to have dental surgery or treatment while you are using the medication. (medlineplus.gov)
A dentist should examine your teeth and perform any needed treatments, including cleaning, before you start to use romosozumab-aqqg injection. (medlineplus.gov)

The results are consistent with our earlier findings that younger women treated with estrogen had a trend toward fewer heart attacks but, for an individual woman, it remains uncertain whether the benefits of estrogen would outweigh the risks. (nih.gov)
Indications for surgical treatment should be based on radiographic findings after initial reduction, expected functional needs, associated medical conditions, and other traumatic injuries (see Surgical Therapy below). (medscape.com)

Most medical treatment of postmenopausal osteoporosis are inhibitors of bone resorption and urinary Deoxypyridinoline (D-Pyr) has been shown to be a reliable indicator of bone resorption. (annals.edu.sg)

Anatomy15

Organisms3

Diseases35

Chemicals and Drugs89

Analytical, Diagnostic and Therapeutic Techniques and Equipment63

Psychiatry and Psychology7

Phenomena and Processes44

Anthropology, Education, Sociology and Social Phenomena5

Technology, Industry, Agriculture7

Humanities1

Information Science2

Named Groups6

Health Care46

Geographicals4

Healthy postmenopausal women6

Management of Postmenopausal Osteoporosis1

Fractures in postmenopausal women1

Premenopausal women6

Prevention7

Effective treatment for postmenopausal2

Menopausal and postmenopausal women2

Osteopenic postmenopausal women1

Hormone38

Menopause31

METHODS4

High Risk For Fracture2

Prevalence12

Symptoms7

Postmenopause3

Orthodontic treatment4

Bone loss7

Fracture risk4

Adjuvant7

Post-menopausal6

Paget's2

Obesity5

Vertebral fractures8

Estrogen therapy4

Cardiovascular disease3

Osteoporotic fracture2

Patients16

Bisphosphonate3

Study40

Diagnosis5

Disease progression2

Clinical5

Osteoporosis treatment1

Beneficial3

Alendronate3

Breast cancer21

Years20

Significantly4

Alternative treatments are not1

Placebo3

Conclusion1

Quality of l3

Risk14

Participants5

Severe1

Mechanism1

Cognitive decline3

Estrogens1

Hyperandrogenism1

Women's3

Abdominal Fat1

Romosozumab5

Findings2

Inhibitors1