Arthritis, RheumatoidAntirheumatic AgentsMethotrexateArthritisIsoxazolesSulfasalazineJointsDrug Therapy, CombinationDouble-Blind MethodSynovial MembraneSeverity of Illness IndexArthritis, ExperimentalBlood SedimentationRheumatoid FactorSynovial FluidTreatment OutcomeAntibodies, MonoclonalHydroxychloroquineGold Sodium ThiomalateArthritis, InfectiousArthrographyFinger JointArthritis, JuvenileTumor Necrosis Factor-alphaAntibodies, Monoclonal, HumanizedReceptors, Tumor Necrosis FactorImmunoglobulin GArthritis, PsoriaticInjections, SubcutaneousAnti-Inflammatory Agents, Non-SteroidalPrednisoloneAntibodies, Monoclonal, Murine-DerivedArthritis, ReactiveImmunoconjugatesGlucocorticoidsSynovitisC-Reactive ProteinOsteoarthritisPlacebosDose-Response Relationship, DrugImmunosuppressive AgentsDisease ProgressionDisability EvaluationDrug Administration ScheduleHealth StatusRheumatoid NoduleMetacarpophalangeal JointAutoantibodiesFollow-Up StudiesProspective StudiesRheumatologyPeptides, CyclicRheumatic DiseasesHLA-DRB1 ChainsWrist JointMice, Inbred DBAHLA-DR4 AntigenHLA-DR AntigensCollagen Type IICitrullineSpondylitis, AnkylosingArthritis, GoutyAutoimmune DiseasesOrganogold CompoundsFoot JointsLupus Erythematosus, SystemicAnti-Inflammatory AgentsPenicillamineKnee JointBiological MarkersInjections, Intra-ArticularCase-Control StudiesHand JointsJoint DiseasesRats, Inbred LewEnzyme-Linked Immunosorbent AssayCytokinesGenetic Predisposition to DiseaseSpondylarthropathiesAuranofinCells, CulturedFelty SyndromeTarsal JointsHand Deformities, AcquiredFibroblastsTenosynovitisT-LymphocytesSjogren's SyndromeImmunoglobulin MProtein Tyrosine Phosphatase, Non-Receptor Type 22AurothioglucoseInflammationAutoantigensInterleukin-6Cohort StudiesAntigen-Antibody ComplexPainDisease Models, AnimalCollagenHand