Interleukin 1 Receptor Antagonist ProteinSialoglycoproteinsReceptors, Interleukin-1Interleukin-1OsteoarthritisOsteoarthritis, KneeOsteoarthritis, HipKnee JointCartilage, ArticularNeurokinin-1 Receptor AntagonistsOsteoarthritis, SpineDose-Response Relationship, DrugPurinergic P1 Receptor AntagonistsRats, Sprague-DawleyHistamine H2 AntagonistsPiperidinesSerotonin 5-HT3 Receptor AntagonistsPain MeasurementPainExcitatory Amino Acid AntagonistsAngiotensin Receptor AntagonistsHand JointsDopamine AntagonistsArthralgiaMenisci, TibialSerotonin 5-HT2 Receptor AntagonistsAdenosine A2 Receptor AntagonistsOsteophyteHormone AntagonistsInjections, Intra-ArticularAdenosine A1 Receptor AntagonistsCells, CulturedSynovial FluidRats, WistarPurinergic P2 Receptor AntagonistsSynovial MembraneNarcotic AntagonistsChondrocytesHistamine H1 AntagonistsReceptors, Endothelin