Cell Migration AssaysCell MovementCell Migration Assays, MacrophageCell Migration Assays, LeukocyteCell ProliferationCell Line, TumorCells, CulturedSignal TransductionCell AdhesionChemotaxisNeoplasm InvasivenessLeukocytesChemotaxis, LeukocyteCell Migration InhibitionLeukocyte RollingWound HealingRNA, Small InterferingEndothelial CellsChemokine CXCL12Blotting, WesternDiffusion Chambers, CultureFibronectinsIntegrinsReceptors, CXCR4Mice, Inbred C57BLCell LineLeukocyte CountFocal AdhesionsEndothelium, VascularReverse Transcriptase Polymerase Chain ReactionRNA InterferenceNeutrophilsActinsPhosphorylationCoculture TechniquesMatrix Metalloproteinase 9LamininTransfectionGene Expression Regulation, NeoplasticAnimal MigrationCell Adhesion MoleculesRNA, MessengerPseudopodiaEpithelial CellsMatrix Metalloproteinase 2Gene Knockdown TechniquesAntigens, CD29Cell PolarityUp-RegulationFlow Cytometryrac1 GTP-Binding ProteinImmunohistochemistryForeign-Body MigrationNeoplasm MetastasisFibroblastsMice, KnockoutTumor Cells, CulturedNeovascularization, PhysiologicExtracellular MatrixChemokines, CXCFocal Adhesion Protein-Tyrosine KinasesCadherinsTime FactorsDose-Response Relationship, DrugDown-RegulationNeovascularization, PathologicCell CommunicationChemokinesCell DifferentiationTransendothelial and Transepithelial MigrationUmbilical VeinsReal-Time Polymerase Chain ReactionCollagenCytoskeletonVascular Endothelial Growth Factor AMicroscopy, FluorescenceMonocytesPhosphatidylinositol 3-KinasesEnzyme ActivationCulture Media, ConditionedProtein BindingPaxillinChemotactic FactorsProto-Oncogene Proteins c-aktCell DivisionAntigens, CDrac GTP-Binding ProteinsApoptosisCell Surface ExtensionsEnzyme InhibitorsEpithelium, CornealMolecular Sequence DataMyocytes, Smooth MuscleGene Expression RegulationReceptors, ChemokineRecombinant ProteinsGliomaGene ExpressionCell SurvivalAntigens, CD18