• In this review of literature, we summarized five potential host cell receptors, as host-cell surface bindings, including angiotensin-converting enzyme 2 (ACE2), neuropilin 1 (NRP-1), dipeptidyl peptidase 4 (DPP4), glucose regulated protein-78 (GRP78), and cluster of differentiation 147 (CD147) related to the SARS-CoV-2 infection. (eurekaselect.com)
  • CD147 , also known as Basigin (BSG) , or extracellular matrix metalloproteinase inducer (EMMPRIN) . (proteinkinase.biz)
  • As members of the immunoglobulin superfamily play fundamental roles in intercellular recognition involved in various immunologic phenomena, differentiation, and development, basigin is thought also to play a role in intercellular recognition and regulate several distinct functions, such as spermatogenesis, expression of the monocarboxylate transporter and the responsiveness of lymphocytes. (proteinkinase.biz)
  • Antigens, CD47" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (rush.edu)
  • This graph shows the total number of publications written about "Antigens, CD47" by people in this website by year, and whether "Antigens, CD47" was a major or minor topic of these publications. (rush.edu)
  • Below are the most recent publications written about "Antigens, CD47" by people in Profiles. (rush.edu)
  • Recombinant Human CD147 /EMMPRIN Protein (rhCD147), His Tag (CD7-H5222) is expressed from human 293 cells (HEK293). (proteinkinase.biz)
  • This protein is also identified as an ovarian-tumor-specific antigen. (childrensmercy.org)
  • 1 2 Cell surface antigens CD38 and CD138 can be used to distinguish normal cells from clonal plasma cells, but more extensive use of immunophenotyping has been limited by a lack of universally accepted markers of MM. 3-5 Once diagnosed, the current standard-of-care for MM includes immunomodulatory drugs, proteasome inhibitors, steroids, and antibody therapies. (bmj.com)
  • Previously we developed a murine monoclonal antibody HAb18 (common named metuximab) focusing on CD147 molecule. (immune-source.com)
  • Besides ACE2, CD147 was discovered as a novel SARS-CoV-2 receptor, CD147 appears to be an alternate receptor for SARSCoV- 2 infection. (eurekaselect.com)
  • The rNDV-18HL-encoded cHAb18 antibody kept affinity for CD147 and showed inhibiting the invasion and migration of HCC cells. (immune-source.com)
  • OncoVEXGM-CSF a recombinant HSV expressing GM-CSF in phase III trial for treatment of melanoma was proved to eliminate malignancy cells by inducing local and systemic antigen-specific T cell reactions and reducing suppressive immune cell populations [12]. (immune-source.com)
  • CD147 is definitely over-expressed in HCC cells and involved in tumor cell invasion [17] and closely related to prognosis in individuals with HCC [18-22]. (immune-source.com)
  • A membrane-bound tumor necrosis family member found primarily on activated T-LYMPHOCYTES that binds specifically to CD30 ANTIGEN. (wakehealth.edu)
  • Blood tests: Over expression of tumour markers like CD147 and fucosyltransferase 8. (omicsonline.org)
  • Biotinylated rh CD147 /EMMPRIN is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 21.6 kDa. (creativebiomart.net)
  • Less than 1.0 EU per μg of the Biotinylated rh CD147 /EMMPRIN by the LAL method. (creativebiomart.net)
  • 1. EMMPRIN/CD147 is an independent prognostic biomarker in cutaneous melanoma. (nih.gov)
  • Transepithelial transportation of lactate can be caused by monocarboxylate transporters (MCTs) in the apical and basolateral walls of the RPE.4 The MCTs are people of the gene family members of transporters. (siamtech.net)
  • It has been implicated in various physiological and pathological activities through interacting with multiple partners, including cyclophilins, monocarboxylate transporters, caveolin-1 and integrins [ 2 - 4 ]. (oncotarget.com)
  • CD147, a transmembrane glycoprotein, is expressed on all leukocytes, platelets and endothelial cells [ 1 ]. (oncotarget.com)
  • While CD147 is best known as a potent inducer of extracellular matrix metalloproteinases, it can also function as a key mediator of inflammatory and immune responses. (oncotarget.com)
  • Previous findings from functional experiments have shown that CD147 is an indicator of tumor prognosis [ 6 ] and it can promote cancer cell migration, invasion and metastasis by enhancing the activity of matrix metalloproteinases by digesting the components of the extracellular matrix in breast cancer, lymphoma, oral squamous cell carcinoma, glioma, melanoma, lung cancer, bladder and kidney carcinomas and ovarian cancer [ 7 - 13 ]. (oncotarget.com)
  • A, B and H antigens mainly elicit IgM antibody reactions, although anti-H is very rare, see the Hh antigen system (Bombay phenotype, ISBT #18). (wikidoc.org)
  • 3. Novel Functions of CD147 in the Mitochondria Exacerbates Melanoma Metastasis. (nih.gov)
  • To systematically elucidate the function of CD147 in cancer cells, we performed an analysis of genome-wide profiling across the Cancer Cell Line Encyclopedia (CCLE). (oncotarget.com)
  • 7. Highly sensitive multivariable assay detection of melanocytic differentiation antigens and angiogenesis biomarkers in sentinel lymph nodes with melanoma micrometastases. (nih.gov)