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  • extracellular
  • In cell biology, a vesicle is a small structure within a cell, or extracellular, consisting of fluid enclosed by a lipid bilayer. (wikipedia.org)
  • Extracellular vesicles (EVs) are produced by all domains of life including complex eukaryotes, both Gram-negative and Gram-positive bacteria, mycobacteria and fungi. (wikipedia.org)
  • Fusion
  • These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. (uniprot.org)
  • Thomas C. Südhof became interested in how vesicle fusion machinery was controlled. (selectscience.net)
  • He unraveled the mechanism by which calcium ions trigger release of neurotransmitters, and identified key regulatory components in the vesicle fusion machinery. (selectscience.net)
  • Vesicle transport and fusion is essential for physiological processes ranging from control of nerve cell communication in the brain to immunological responses and hormone section. (selectscience.net)
  • cytosolic
  • the second H+ efflux is coupled with a second large conformational change that leads to amine transport from the cytosolic side into the vesicle, reducing amine-binding affinity. (wikipedia.org)