• Stem cells from a donor (also called an allogeneic transplant). (cdc.gov)
  • A transplant using stem cells from a donor increases your risk for fungal infection more than a transplant that uses stem cells from your own body. (cdc.gov)
  • If you receive stem cells from a donor, the transplanted stem cells may attack your body. (cdc.gov)
  • The research was a proof-of-concept for the process, demonstrating that in the future, we may simply grow someone a new liver rather than giving them a donor organ transplant. (slashgear.com)
  • The organs were created by removing muscle cells from donor organs to leave behind tough hearts of connective tissue. (dailymail.co.uk)
  • Researchers have stated that the patient received a novel stem cell transplant from a donor who was naturally resistant to the virus, and that the outcome was successful. (gcn.ie)
  • When a person needs a bone marrow transplant, doctors must retrieve and harvest stem cells from that individual or a donor. (popsci.com)
  • To make the blood, RESTORE scientists obtain a standard pint-sized blood donation from a human donor. (extremetech.com)
  • Such transplants involve replacing damaged marrow with bone marrow stem cells from a healthy donor. (newscientist.com)
  • But first, the recipient must have their own bone marrow stem cells wiped out to make room for the transplanted donor cells. (newscientist.com)
  • It provides a home for donor cells to grow and proliferate, bypassing the need for any drug and radiation treatment. (newscientist.com)
  • The inner matrix creates a home for donor bone marrow stem cells. (newscientist.com)
  • Blood cells made by the donor stem cells inside the implant were able to get into circulation where they mixed with the host's own blood cells. (newscientist.com)
  • Six months later, blood cells from both the donor and host were still circulating around the body. (newscientist.com)
  • In an islet transplant, doctors take healthy islets from the pancreas of an organ donor, and inject them into someone with type 1 diabetes. (diabetesresearch.org)
  • This could include finding a method to regenerate a patient's own pancreatic cells, so cells don't have to be taken from a donor. (diabetesresearch.org)
  • The donor had a mutation called CCR5 Delta 32 that made his blood cells nearly immune to HIV because it averts the virus entry. (biosstemcells.com)
  • Another point of interest is graft-versus-host disease, which occurs when cells from the donor attack the recipient's cells, and that was not developed by the only participant with detectable reservoir. (biosstemcells.com)
  • The first tracheal transplant operation was performed only in 1998 in Cleveland (USA), and the patient was doomed to take immunosuppressive drugs for the rest of his life so that the rejection of the donor organ would not occur. (vechnayamolodost.ru)
  • Donor Killer Cell Immunoglobulin-Like Receptor Genotype Does Not Improve Graft-versus-Leukemia Responses in Chronic Lymphocytic Leukemia after Unrelated Donor Transplant: A Center for International Blood and Marrow Transplant Research Analysis. (anthonynolan.org)
  • NK cells can also be collected from donor blood or umbilical cord blood and given, unchanged, to patients. (ohsu.edu)
  • Then, he or she receives a bone marrow transplant from a healthy donor. (medlineplus.gov)
  • BACKGROUND AND OBJECTIVES: The COVID-19 pandemic profoundly influenced unrelated donor (UD) allogeneic peripheral blood stem cell (PBSC) collections. (bvsalud.org)
  • if it implants and the pregnancy goes to term, the resulting individual will carry the same nuclear genetic material as the donor of the adult somatic cell. (who.int)
  • However, an animal created through this technique would not be a precise genetic copy of the source of its nuclear DNA because each clone derives a small amount of its DNA from the mitochondria of the egg (which lie outside the nucleus) rather than from the donor of cell nucleus. (who.int)
  • This may also be complementary to the approach of haploidentical adult stem cell transplants, which involve donors from a close but still mismatched family member. (scitechdaily.com)
  • Drowsy mice make poor stem cell donors, according to a new study by researchers at the Stanford University School of Medicine. (sleepreviewmag.com)
  • These transplants come from donors at this time, meaning the recipient must take anti-rejection drugs for the rest of their life. (slashgear.com)
  • He added that "The ability to use partially matched umbilical cord blood grafts greatly increases the likelihood of finding suitable donors for such patients. (gcn.ie)
  • A fast process would also improve the experience for healthy donors who volunteer to give stem cells-which might attract more people. (popsci.com)
  • We hope our lab-grown red blood cells will last longer than those that come from blood donors," said the study's chief investigator Professor Cedric Ghevaert, consultant hematologist at the University of Cambridge and NHSBT, in a statement (Opens in a new window) . (extremetech.com)
  • This site provides information, referrals, and support by trained peer volunteers who are transplant survivors, caregivers, and donors. (myeloma.org)
  • In addition, the identification of this gene may help provide a genetic test that could be applied to blood stem cell donors and recipients to increase opportunities for successful transplants. (labcanada.com)
  • A method that broadens the pool of potential donors for stem cell transplants recently saved two young brothers from a severe genetic disease. (stanford.edu)
  • All donors lack the CCR5 Delta 32 mutation on their blood cells. (biosstemcells.com)
  • The authors confirmed that cells derived from both PD patients and healthy donors made dopamine in vivo, at levels about half that of cells in normal monkeys. (the-scientist.com)
  • In the planned clinical trial, the research team will use iPSCs derived from healthy donors , not from the subjects' own cells, which could raise issues with graft rejection. (the-scientist.com)
  • BACKGROUND: Severe T-cell lymphopenia of uncertain clinical significance has been observed in frequent apheresis platelet donors. (bvsalud.org)
  • STUDY DESIGN AND METHODS: We performed an international, multicenter, observational study comparing T-cell populations in frequent platelet donors collected exclusively using the Trima instrument (n = 131) or the Amicus instrument (n = 77). (bvsalud.org)
  • Age- and sex-matched whole blood donors (n = 126) served as controls. (bvsalud.org)
  • These stem cells come from developed organs and tissues in the body. (healthline.com)
  • There are many hurdles to overcome to generate a fully functioning heart, but my prediction is that it may one day be possible to grow entire organs for transplant. (dailymail.co.uk)
  • The lab-grown organs have been created using these types of cells - the body's immature 'master cells' which have the ability to turn into different types of tissue. (dailymail.co.uk)
  • However, it was not until 1998 that the prospect of being able to use stem cells to regenerate damaged organs became possible, when James Thompson at the University of Wisconsin, and John Gearhart from John Hopkins University grew the first human embryonic stem cells. (womens-health.co.uk)
  • Without insulin, sugar builds up in the blood and can damage your internal organs, including your heart, kidneys, eyes, nervous system, and other parts of the body. (diabetesresearch.org)
  • This is one of the most difficult to transplant organs of the human body, firstly, because of the huge number of small blood vessels, without which the trachea is not viable, and secondly, because of its proximity to the aggressive environment of the outside world and the high risk of infection. (vechnayamolodost.ru)
  • The success in heart, liver, kidney and lung transplantology is largely due to the fact that when transplanting these organs, the task of attaching one major artery and one major vein is solved, and the organs are to a certain extent fenced off from the outside world. (vechnayamolodost.ru)
  • These fatty materials are stored naturally in the body's cells, organs, and tissues. (nih.gov)
  • Printing complex cell types and organs have proved to be difficult. (interestingengineering.com)
  • Our facilities provide the opportunity to study molecules, cells, organs and entire organisms. (lu.se)
  • Researchers from the Stowers Institute for Medical Research and collaborators have identified a way to expand blood-forming, adult stem cells from human umbilical cord blood (hUCB). (scitechdaily.com)
  • In the study, published online on July 31, 2018, in Cell Research, researchers zeroed in on a protein that affects multiple targets and pathways involved in hematopoietic stem cell self-renewal, a broader approach than other studies that focus on a single target or pathway in the process. (scitechdaily.com)
  • A sleep deficit of just four hours affects by as much as 50 percent the ability of stem cells of the blood and immune system to migrate to the proper spots in the bone marrow of recipient mice and churn out the cell types necessary to reconstitute a damaged immune system, the researchers found. (sleepreviewmag.com)
  • Using cells scraped from a person's skin, researchers grew miniature human livers in a lab and then successfully transplanted them into living rats. (slashgear.com)
  • The study was recently published in Cell Reports , where researchers detail the experiment and its results. (slashgear.com)
  • Researchers then injected stem cells which multiplied and grew around the structure, eventually turning into healthy heart cells. (dailymail.co.uk)
  • The experiment follows a string of successes for researchers trying to create spare body parts for transplants. (dailymail.co.uk)
  • Lab-grown blood could fill this gap-and researchers are already testing the stuff in human study participants. (extremetech.com)
  • Because these cells are at this specific stage, researchers actually expect recipients' bodies to accept the lab-grown blood at a higher rate than they would a standard blood transfusion. (extremetech.com)
  • RESTORE researchers have officially transfused the lab-grown blood into two healthy recipients, each of whom received five to 10 milliliters (approximately one to two teaspoons). (extremetech.com)
  • Mild radioactive "tagging" of the lab-grown blood cells allows researchers to monitor which reactions are a result of the experimental transfusion. (extremetech.com)
  • The researchers reported that the AMSCs successfully migrated to the retinas of the test animals and, because of the growth factors secreted by the cells, were able to suppress retinal neovascularization. (genengnews.com)
  • The researchers concluded that although further studies are needed to confirm the effect of AMSCs on neovascular diseases, the data collected in their study provided insights into the mechanisms by which these cells exert their therapeutic effects. (genengnews.com)
  • Researchers are comparing chemical alterations, called DNA methylation, in the body's basic building block in healthy colon, breast, brain and lymphatic cells and their cancerous counterpart to find telltale patterns that could one day be detected in the blood, urine or feces. (sciencedaily.com)
  • Next, the researchers followed a well-established protocol for differentiating embryonic stem cells into precursors of bone marrow adult stem cells, which can be transplanted into mice to generate normal blood cells. (medicalxpress.com)
  • Stanford researchers study stem-cell-derived human heart muscle cells on the International Space Station to learn effects of microgravity. (stanford.edu)
  • A team of researchers have found a new way to remove blood-producing stem cells, introducing the possibility of safer, and non-matched, transplants. (stanford.edu)
  • Finally, researchers are investigating how to increase the supply of islets available for transplant. (diabetesresearch.org)
  • Now, researchers from the IrsiCaixa AIDS Research Institute (Barcelona, Spain) and the Gregorio Marañón Hospital (Madrid, Spain), point out certain mechanisms associated with stem cell transplant that might contribute to HIV reservoir eradication, after 5 patients who received a stem cell transplant have undetectable HIV reservoir and HIV antibodies are no longer found in one of them. (biosstemcells.com)
  • In order to counteract these unintended consequences of antibiotic treatments, researchers are looking to FMTs (also known as stool transplants). (mskcc.org)
  • In a study published today (August 30) in Nature , an international team of researchers improved symptoms in a monkey model of PD by grafting dopamine-producing neurons derived from human induced pluripotent stem cells (iPSCs) into the monkeys' brains. (the-scientist.com)
  • Then, the researchers grafted the reprogrammed cells into the brains of 2- to 3-year-old, male cynomolgus monkeys ( Macaca fascicularis ) that had been treated with the neurotoxin MPTP, which kills dopamine-releasing neurons and results in PD-like movement defects. (the-scientist.com)
  • The same researchers are now creating embryo-stage versions of people to harvest tissues for use in transplant treatments. (interestingengineering.com)
  • hero" is the right word for how Hwang Woo-suk is revered by the media -- and by a large section of the Korean public who have bought into the false promises of embryonic stem cell and cloning researchers. (blogspot.com)
  • A Korean television station whose investigative report was the nail in the coffin that prompted human cloning scientist Hwang Woo-suk to admit he lied about egg donations his researchers made says he may have lied about the results of his research as well. (blogspot.com)
  • Researchers hope to use stem cells to repair or replace cells or tissues damaged or destroyed by such disorders as Parkinson disease, diabetes, and spinal injuries. (msdmanuals.com)
  • By triggering certain genes, researchers may be able to cause the stem cells to specialize and become the cells that need to be replaced. (msdmanuals.com)
  • Researchers and health professionals consider stem cells to be an important weapon in the fight against diseases, particularly those that have resisted the efforts of science for a long time, and they have become the subject of a great deal of recent research. (bvsalud.org)
  • Researchers at Lund University have instead chosen to investigate what protects the insulin-producing cells. (lu.se)
  • Previous studies by the same researchers have shown that C3 is also present inside cells and plays an important role there. (lu.se)
  • An objective among many diabetes researchers is to create treatments where stem cells are taken from the patient and converted into insulin-producing cells, which are then transplanted back into the patient. (lu.se)
  • Among researchers studying the immune system, there is no consensus on whether C3 plays a significant role inside our cells. (lu.se)
  • Below you can see some examples of the infrastructure for research on genes and cells, available for researchers at Lund University. (lu.se)
  • Adult stem cells from umbilical cords are more likely to be a match for more people because there are fewer compatibility requirements than for a bone marrow transplant. (scitechdaily.com)
  • This work represents a path forward by demonstrating the ability to reliably expand adult stem cells from umbilical cord blood in the laboratory without terminally differentiating the cells into more mature and relatively short-lived blood cells," says Joseph McGuirk, MD, professor of medicine and medical director of blood and marrow transplant at the University of Kansas Health System, who was not directly involved with the study. (scitechdaily.com)
  • This significant discovery led to the first human bone marrow transplant by E. Donnall Thomas in 1956, which although successful in saving lives, has generated much controversy since. (wikipedia.org)
  • Scientists are hoping this gene discovery will lead to the development of a therapy that would mimic the effects of SIRPalpha and create conditions for a successful bone marrow transplant. (labcanada.com)
  • The only participant with a detectable HIV reservoir received a cord blood transplant -the other cases had a bone marrow transplant- and showed delayed achievement of complete replacement of his cells by donor's cells (18 months). (biosstemcells.com)
  • Their recent research aims to help more patients find a cure through expanded bone marrow transplant treatment and gene therapy. (medlineplus.gov)
  • In a more traditional bone marrow transplant, a patient is first treated with chemotherapy. (medlineplus.gov)
  • Recent research on adult stem cells has found adult stem cells in many more tissues than once thought possible. (news-medical.net)
  • iPSCs directed to differentiate into specific cell types offer the possibility of a renewable source of replacement cells and tissues to treat ailments, including Parkinson's disease, spinal cord injury, heart disease, diabetes, and arthritis. (medindia.net)
  • Five of them had undetectable reservoir in blood and all analysed tissues. (biosstemcells.com)
  • Lipid storage diseases (also known as lipidoses) are a group of inherited metabolic disorders in which harmful amounts of fatty materials (lipids) accumulate in various cells and tissues in the body. (nih.gov)
  • Because of this special power, stem cells can help replace or reconstruct damaged cells and tissues. (growwithvitality.com)
  • The term "regenerative medicine" is a broad term covering any type of medicine that aims to help the body repair damaged cells or tissues. (growwithvitality.com)
  • Many studies have shown the utility of embryonic or adult stem cells for forming teeth and for regeneration of bone and soft tissues. (bvsalud.org)
  • Adult stem cells are classified as pluripotent and are undifferentiated cells that remain quiescent in tissues until stimulated, when they can create cell types that are compatible with the tissue in which they reside. (bvsalud.org)
  • Additionally, they can form specialized cell types from other tissues if they are transplanted 6 . (bvsalud.org)
  • Stromal cells are a mixed population that can create bone, cartilage and fat and also fibrous and connective tissues. (bvsalud.org)
  • Our facilities provide the opportunity to study protein structure, molecular probes and drug design, system biology and molecular interactions in cells and tissues. (lu.se)
  • He and his colleagues, in collaboration with the Broad Institute of Harvard and MIT, analyzed some 17,000 blood samples, searching for mutations in nearly 200 genes known to be associated with blood cancers. (dana-farber.org)
  • They also discovered that these mutated genes coincided with the abnormal expansion of the blood cells that harbor them - a phenomenon known as clonal hematopoiesis (CH) . (dana-farber.org)
  • In animal studies conducted in collaboration with Peter Libby, MD, at Brigham and Women's Hospital, they showed that blood cells carrying one of the commonly mutated genes associated with CH can accelerate the onset of heart disease in mice. (dana-farber.org)
  • Distinctive patterns of genes turned off -- or left on -- in healthy versus cancerous cells could enable early screening for many common cancers and maybe help avoid them scientists say. (sciencedaily.com)
  • DNA methylation is a piece of a relatively new research field called epigenetics that looks more globally at which genes are turned off and on with an eye on early identification of some of the aberrant adjustments that enable cancer cells to thrive. (sciencedaily.com)
  • A lot of methylated genes we found in cancer are not naturally expressed in normal cells. (sciencedaily.com)
  • Dr. Robertson, who also works in breast cancer and brain tumors as well as colon cancer, is finding patterns of genes that regulate healthy cell differentiation are shut off in cancers. (sciencedaily.com)
  • These are genes that may need to be active during a certain period of development but once you have committed to become a certain cell type, like a skin cell, you need to turn the gene off," he says. (sciencedaily.com)
  • A lot of people think of cancer cells turning genes on, like oncogenes, that allow them to grow faster, evade immune surveillance, that sort of thing," Dr. Robertson says. (sciencedaily.com)
  • The mouse model had been designed to include relevant human genes involved in blood production, including the defective version of that gene. (medicalxpress.com)
  • These cells were modified by a standard lab technique employing retroviruses customized to insert genes into the cell's DNA. (medicalxpress.com)
  • The inserted genes were Oct4, Sox2, Lif4 and c-Myc, known to act together as master regulators to keep cells in an embryonic-stem-cell-like state. (medicalxpress.com)
  • Potential alternatives include other forms of viruses, synthesized versions of the proteins created by the four master regulator genes that are modified to enter the cell nucleus, and small molecules, Hanna says. (medicalxpress.com)
  • Genes that control stem cells could also play a role in other blood disease processes like leukemia and anemia," says Dr Dick. (labcanada.com)
  • Our scientists pursue every aspect of cancer research-from exploring the biology of genes and cells, to developing immune-based treatments, uncovering the causes of metastasis, and more. (mskcc.org)
  • One problem with bone marrow transplants is that you need to have a family member whose genes match,' says Dr. Rodgers. (medlineplus.gov)
  • Now we can take the patient's own bone marrow, use an engineered virus that carries genes to the bone marrow, and give repaired bone marrow stem cells back to the patient so that healthy bone marrow cells can grow,' Dr. Tisdale says. (medlineplus.gov)
  • One way to induce these cells is to inject them with material that affects their genes, a process called reprogramming. (msdmanuals.com)
  • Scientists were initially interested in somatic-cell nuclear transfer as a means of determining whether genes remain functional even after most of them have been switched off as the cells in a developing organism assume their specialized functions as blood cells, muscle cells, and so forth. (who.int)
  • The fact that the DNA of a fully differentiated (adult) cell could be stimulated to revert to a condition comparable to that of a newly fertilized egg and to repeat the process of embryonic development demonstrates that all the genes in differentiated cells retain their functional capacity, although only a few are active. (who.int)
  • Below is a non-exhaustive list of in-house infrastructures that are categorized into three overarching themes: bio-imaging, proteins, genes & cells and other resources. (lu.se)
  • In addition to infrastructures for bioimaging, protein and genes & cells, we also provide other resources e.g., databases, networks and specialized labs. (lu.se)
  • The stem cell controversy is the consideration of the ethics of research involving the development and use of human embryos. (wikipedia.org)
  • Not all stem cell research involves human embryos. (wikipedia.org)
  • The discovery of adult stem cells led scientists to develop an interest in the role of embryonic stem cells, and in separate studies in 1981 Gail Martin and Martin Evans derived pluripotent stem cells from the embryos of mice for the first time. (wikipedia.org)
  • However, the use of the technique on human embryos led to more widespread controversy as criticism of the technique now began from the wider public who debated the moral ethics of questions concerning research involving human embryonic cells. (wikipedia.org)
  • Embryonic stem cells come from human embryos that are three to five days old. (healthline.com)
  • Scientists have transformed stem cells from adult human bone marrow into nerve cells by transplanting them into damaged chicken embryos. (bbc.co.uk)
  • The embryos were kept in spinning jars and bathed in nutritious blood serum and oxygen. (interestingengineering.com)
  • In the new research, Hanna used the same mechanical womb, but this time to grow look-alike embryos created from stem cells. (interestingengineering.com)
  • However, Hanna added these synthetic mouse embryos to his mechanical womb, growing them further than ever before - to a point where the hearts started beating, blood began moving, and 'there was the start of a brain and a tail. (interestingengineering.com)
  • In the next stage, Hanna is using his blood or skin cells, including those of a few other volunteers, as the starting point for making synthetic human embryos. (interestingengineering.com)
  • Stem cells can be obtained from the embryos that are not used. (msdmanuals.com)
  • Because the embryos then lose the ability to grow into a complete human being, the use of stem cells from embryos is controversial. (msdmanuals.com)
  • And in 2019, a study by DRI scientists showed that a small group of patients who received islet transplants had been able to live without insulin injections for 10 years, while maintaining blood sugar levels that were in the same range as people who had never had type 1 diabetes. (diabetesresearch.org)
  • In early 2009, the FDA approved the first human clinical trials using embryonic stem cells. (wikipedia.org)
  • While most panelists felt that clinical use of pancreatic stem cells as a cure for diabetes was 15-20 years away, they also believed that application of stem cell therapies would likely include spinal cord injuries, Parkinson's disease and dementia. (news-medical.net)
  • It takes multiple days of injections with GCSF before stem cells can be harvested, under current clinical practice. (popsci.com)
  • Search clinical trials for adult and pediatric cancers and blood disorders offered through Dana-Farber and our clinical partners. (dana-farber.org)
  • Now, scientists are hoping to soon launch clinical trials of potential therapeutics that may be able to disrupt the inflammatory program spurred by clonal hematopoiesis of indeterminate potential (CHIP) and reduce the risk of heart disease. (dana-farber.org)
  • At least eight more clinical trial participants will receive lab-grown blood transfusions at least four months after receiving a standard blood transfusion, which will allow the RESTORE team to compare physical reactions to each. (extremetech.com)
  • The scientists believe that their technique may advance stem cell therapy toward clinical practice and offer novel therapies for eye diseases in people. (genengnews.com)
  • A resource for scientists and clinicians that highlights the latest basic, clinical and translational research in bone and mineral metabolism. (myeloma.org)
  • This site provides information about stem cell transplants provided by the American Society of Clinical Oncology (ASCO). (myeloma.org)
  • Storb, who heads the Transplant Biology Program in the Clinical Research Division, submitted a short paper to the foundation summarizing his development of the 'mini-transplant' a decade ago and new research he is doing to improve the procedure. (fredhutch.org)
  • A state-of-the-field review of stem cell research by Stanford's Helen Blau reveals their promise & exposes problems in the path to clinical applications. (stanford.edu)
  • DRI scientists have a number of clinical trials currently underway, including an islet transplant study that is testing the omentum as an alternative transplant site to the liver. (diabetesresearch.org)
  • A randomized clinical trial at Memorial Sloan Kettering Cancer Center (MSK) has shown that fecal microbiota transplants (FMTs) can reestablish the health-promoting bacteria that are often damaged by intense antibiotic treatment in people who have stem cell or bone marrow transplants for blood cancer. (mskcc.org)
  • This is an important step in the translation of iPSC-derived technology to clinical cell transplants in Parkinson's," Patrik Brundin , a neuroscientist at the Van Andel Institute in Michigan who did not participate in the work, tells The Scientist . (the-scientist.com)
  • We need to confirm efficacy and safety of the cells which will be used in the clinical trial. (the-scientist.com)
  • Since this is a highly sought after clinical goal, we are elucidating the mechanisms of immune cell recruitment so they can be targeted to kill cancer cells. (umn.edu)
  • CONCLUSION: Given the clinical benefits for treatment of trauma, CSP is a desirable addition to a blood formulary. (bvsalud.org)
  • Stem cells from your own body (also called an autologous transplant). (cdc.gov)
  • Right now, GCSFs don't work for some patients who might benefit from autologous stem cell transplants-a procedure where doctors harvest a person's own stem cells and use them to replace their unhealthy bone marrow, that's used in conditions like Hodgkin's lymphoma-because they often don't work in people who have had chemotherapy in the past. (popsci.com)
  • In the paper, publishing September 26 in the ISSCR's journal Stem Cell Reports , published by Cell Press, iPSCs from nonhuman primates successfully developed into the neurons depleted by Parkinson's disease while eliciting only a minimal immune response. (medindia.net)
  • HSCI scientists have developed new ways to identify, grow, sort, and transplant the dopamine-producing cells that are lost in Parkinson's disease . (cryo-cell.com)
  • CENTER FOR IPS CELL RESEARCH AND APPLICATION, KYOTO UNIVERSITY C ell therapy for Parkinson's disease (PD) is closer than ever. (the-scientist.com)
  • Although the research was done in laboratory mice, the findings have possible implications for human stem cell transplants. (sleepreviewmag.com)
  • The panel was responding to recently published research where pancreatic insulin-producing islet cells were discovered in mice. (news-medical.net)
  • In a study in mice, the drug pull stem cells out of the bone marrow quickly and efficiently. (popsci.com)
  • It worked quickly, and the cells could be extracted from the mice within two hours. (popsci.com)
  • First, they tested Viagra alone in a set of mice, which didn't have a large effect on the movement of stem cells. (popsci.com)
  • Next, the team tested Viagra along with a single dose of Plerixafor, which mobilizes stem cells, in another set of mice-and the combination significantly increased the number of circulating stem cells in only two hours. (popsci.com)
  • Scientists in South Korea transplanted mesenchymal stromal cells (MSCs) derived from human amniotic membranes of the placenta (AMSCs) into laboratory mice modeled with oxygen-induced retinopathy. (genengnews.com)
  • Mice with a human sickle-cell anemia disease trait have been treated successfully in a process that begins by directly reprogramming their own cells to an embryonic-stem-cell-like state, without the use of eggs. (medicalxpress.com)
  • This is the first proof-of-principle of therapeutic application in mice of directly reprogrammed "induced pluripotent stem" (IPS) cells, which recently have been derived in mice as well as humans. (medicalxpress.com)
  • To create the IPS cells, the scientists started with cells from the skin of the diseased mice, explains lead author Jacob Hanna, a postdoctoral researcher in the Jaenisch lab. (medicalxpress.com)
  • To decrease or eliminate possible cancer in the treated mice, the c-Myc gene was removed by genetic manipulation from the IPS cells. (medicalxpress.com)
  • The scientists created such precursor cells from the IPS cells, replaced the defective blood-production gene in the precursor cells with a normal gene, and injected the resulting cells back into the diseased mice. (medicalxpress.com)
  • The blood of treated mice was tested with standard analyses employed for human patients. (medicalxpress.com)
  • The analyses showed that the disease was corrected, with measurements of blood and kidney functions similar to those of normal mice. (medicalxpress.com)
  • Toronto, ON - University Health Network researcher Dr John Dick and Hospital for Sick Children collaborator Dr Jayne Danska have discovered a gene with properties allowing successful engraftment of stem cells from human bone marrow into mice. (labcanada.com)
  • The cells can be used as a vaccine to prevent pancreatic cancers in mice. (stanford.edu)
  • Stanford scientists have conducted a proof-of-concept experiment in mice that shows they can use blood stem cells to treat a severe brain disease. (stanford.edu)
  • Following radiation, the bone marrow shows nearly complete loss of blood cells in mice (left). (healthcare-in-europe.com)
  • Mice treated with the PTP-sigma inhibitor displayed rapid recovery of blood cells (purple, right). (healthcare-in-europe.com)
  • In that study, the scientists found that in mice with a PTP-sigma gene deficiency, blood stem cells regenerated faster after they were suppressed by radiation . (healthcare-in-europe.com)
  • Those human blood stem cells were then transplanted into immune-deficient mice, where the cells were able to survive and function properly. (healthcare-in-europe.com)
  • in mice treated with the PTP-sigma inhibitor, white blood cell counts had already recovered to normal levels. (healthcare-in-europe.com)
  • We are now doing these experiments using rats and mice," he writes in an email to The Scientist . (the-scientist.com)
  • Rb1 and Pten Co-Deletion in Osteoblast Precursor Cells Causes Rapid Lipoma Formation in Mice. (umn.edu)
  • Co-deleting Pten with Rb in retinal progenitor cells in mice results in fully penetrant bilateral retinoblastomas. (umn.edu)
  • Some people with hemoglobin H disease need frequent blood transfusions to help them grow and develop well. (childrensmn.org)
  • Blood transfusions deliver healthy hemoglobin and RBCs to the body. (childrensmn.org)
  • After they're born, babies with alpha thalassemia major need frequent blood transfusions to survive. (childrensmn.org)
  • People with hemoglobin H and alpha thalassemia major also buildup extra iron in the body, either from the disease itself or from frequent blood transfusions. (childrensmn.org)
  • Blood transfusions are vital to helping patients overcome health obstacles from physical trauma and lengthy surgeries to leukemia and kidney disease. (extremetech.com)
  • If our trial, the first such in the world, is successful, it will mean that patients who currently require regular long-term blood transfusions will need fewer transfusions in the future, helping transform their care. (extremetech.com)
  • The need for normal blood donations to provide the vast majority of blood transfusions will remain. (extremetech.com)
  • It was also known to affect intravenous drug users and some were known to have contracted it through blood transfusions. (ihv.org)
  • These cells can only serve a specific purpose in a particular organ. (healthline.com)
  • This means they can potentially produce new cells for any organ or tissue. (healthline.com)
  • This will help prevent the immune system from rejecting an organ transplant. (healthline.com)
  • This is not ideal and medical science has long dreamed about a day when a patient's own organ could be grown in a lab and then transplanted into their body. (slashgear.com)
  • One of the biggest is getting enough oxygen to the organ through a complex network of blood vessels. (dailymail.co.uk)
  • Dr Taylor told the Sunday Times: 'We are a long way off creating a heart for transplant, but we think we've opened a door to building any organ for human transplant. (dailymail.co.uk)
  • Great Iranian Muslim scholars netics, stem cell research, and organ trans- laid huge emphasis on teaching and practis- plantation are some of the medical issues ing ethics. (who.int)
  • The panelists were unanimous in their enthusiasm that this research, conducted jointly at the Universities of Alberta and Toronto, adds more hope to the goal of getting human stem cells to produce insulin, and thus finding a cure for diabetes. (news-medical.net)
  • Adult human stem cells should have less controversy compared to embryonic human stem cells in terms of ethical issues. (news-medical.net)
  • The goal is to supplement the natural blood supply with fabricated red blood cells, which are grown from human stem cells. (extremetech.com)
  • Some of the specific variations that were found in humans line up with the positions of the gene that were found to be responsible for human stem cell support in the mouse transplant setting. (labcanada.com)
  • Recent work by DRI scientists has included the discovery of pancreatic stem cells that can be stimulated to create insulin-producing beta cells, and a study that demonstrated that abdominal tissue called the omentum could work as a transplant site. (diabetesresearch.org)
  • This site provides information about bone marrow or cord blood transplant process for patients, their families, and health care providers. (myeloma.org)
  • This development could make these cells available to more people, and be more readily accepted in those who undergo adult stem cell treatments for conditions such as leukemia, blood disorders, immune system diseases, and other types of cancers, but who do not have an appropriate available bone marrow match. (scitechdaily.com)
  • In 1995 adult stem cell research with human use was patented (US PTO with effect from 1995). (wikipedia.org)
  • However, some evidence suggests that adult stem cell plasticity may exist, increasing the number of cell types a given adult stem cell can become. (wikipedia.org)
  • If this differentiation of adult stem cells can be controlled in the laboratory, these cells may become the basis of therapies for many serious common diseases. (news-medical.net)
  • Stem cell therapies are already being used to treat various cancers and disorders of the blood and immune system. (pharmanews.eu)
  • We have worked for a decade to help develop new therapies, first for blood cancers and now rapidly expanding to other cancer types. (ohsu.edu)
  • In the long term, the knowledge about C3 can be used to develop new treatments aimed at protecting the insulin-producing cells, such as stem cell therapies for treating type 1 diabetes and type 2 diabetes. (lu.se)
  • Recent research uncovers a new approach for expanding blood-forming, adult stem cells from human umbilical cord blood. (scitechdaily.com)
  • For many decades, stem cells have played an important role in medical research, beginning in 1868 when Ernst Haeckel first used the phrase to describe the fertilized egg which eventually gestates into an organism. (wikipedia.org)
  • Great levels of success and potential have been realized from research using adult stem cells. (wikipedia.org)
  • Destruction of a human embryo is required in order to research new embryonic cell lines. (wikipedia.org)
  • Political leaders debate how to regulate and fund research studies that involve the techniques used to remove the embryo cells. (wikipedia.org)
  • However, more research is needed to help understand the potential uses of amniotic fluid stem cells. (healthline.com)
  • In addition to the current federally imposed restrictions on stem cell research, they also saw cost as a major inhibiting factor, including sterilization, preservation of cells, consistency of product and delivery of cells. (news-medical.net)
  • The panelists acknowledged the current ethical concerns surrounding stem cell research, but most felt that the impediments to research put in place by the current administration were unfortunate, and that science preceded ethics on most issues. (news-medical.net)
  • One panelist even added, "If the political hurdle would be removed, I believe there is a lot of pent-up momentum from both scientists and drug companies [for stem cell research]. (news-medical.net)
  • Since adult stem cells avoid the ethical debate surrounding embryonic stem cells , most scientists on the panel feel more comfortable pursuing this line of research. (news-medical.net)
  • New research in monkeys refutes these findings, suggesting that in primates like us, such cells will not be rejected by the immune system. (medindia.net)
  • Smith-Berdan and Forsberg study the mechanisms that help stem cells move in and out of the bone marrow, and in previous research, found that the more permeable the blood vessels around the bone marrow were, the more easily stem cells moved into the bloodstream. (popsci.com)
  • Interest in embryonic stem cells has exploded in the last decade as medical advancements have forced the public to question the moral viability of this controversial research. (womens-health.co.uk)
  • However, the origins of stem cell research dates back much farther than that. (womens-health.co.uk)
  • But bone growing research is still at early stages, and bone which can sustain and survive with its own blood vessel structures, for instance, is some way off. (bbc.co.uk)
  • Despite the rapid progress being made with IPS cells, Jaenisch emphasizes that this field is very young, and that it's critical to continue full research on embryonic stem cells as well. (medicalxpress.com)
  • A structurally similar protein in mammals could aid stem cell research. (stanford.edu)
  • Research has come a long way since the first islet transplant in a human was performed in 1985. (diabetesresearch.org)
  • Our goal is to elucidate the factors that help to eradicate the virus after transplant, and then mimic them with safer alternative strategies than this intervention," concludes Javier Martínez-Picado, ICREA research professor at IrsiCaixa and co-leader of the article. (biosstemcells.com)
  • OHSU's Dr. Richard Maziarz leads research on CAR T-cell therapy, a type of immunotherapy that's bringing powerful new options to children and adults with blood cancer. (ohsu.edu)
  • CENTER FOR IPS CELL RESEARCH AND APPLICATION, KYOTO UNIVERSITY Brundin says it's not surprising that cells derived from people with PD were about as effective as those from healthy people. (the-scientist.com)
  • Hanna's research was published in the journal Cell on Monday. (interestingengineering.com)
  • However, Korean television station MBC has conducted interviews with an unnamed member of Hwang's research team who says the cells were never cloned successfully. (blogspot.com)
  • Bringing together Universities and high school students, UniStem Day is an opportunity to foster learning, discovery and debate in the field of stem cell research - inspiring the scientists of tomorrow. (lu.se)
  • Many people with sickle cell disease (SCD) are healthier and living longer thanks in part to research led and supported by the National Institutes of Health (NIH). (medlineplus.gov)
  • Many people don't realize the severity of this disease,' says John Tisdale, M.D., senior investigator at NIH's National Heart, Lung, and Blood Institute, who leads NIH sickle cell disease research along with Griffin Rodgers, M.D., director of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). (medlineplus.gov)
  • Somatic-cell nuclear transfer, the technique by which Dolly was created, was first used 40 years ago in research with tadpoles and frogs. (who.int)
  • Much research on diabetes focuses on understanding what happens when the insulin-producing cells are destroyed. (lu.se)
  • Their research shows that a protein of the immune system protects the insulin-producing cells from inflammation and death. (lu.se)
  • Much research on diabetes focuses on trying to understand what happens when the insulin-producing cells are destroyed. (lu.se)
  • If we can increase the production of intracellular C3 in these cells, it may help the cells survive longer so that the treatment can be more effective," says Ben C King, associate professor of inflammation research at Lund University, and co-senior author of the study. (lu.se)
  • Since its foundation, the WCMM research school has encouraged young scientists to exchange ideas and foster collaborations while keeping up with the latest techniques. (lu.se)
  • Many less controversial sources of acquiring stem cells include using cells from the umbilical cord, breast milk, and bone marrow, which are not pluripotent. (wikipedia.org)
  • Cord blood stem cells are harvested from the umbilical cord after childbirth. (healthline.com)
  • The middle-aged female patient was the first to undergo a haplo-cord transplant, where umbilical cord blood is used in what is a newer method that is accessible to more people. (gcn.ie)
  • But before you take a side, get the facts on why stem cells are causing such a stir and how umbilical cord blood may be the answer to avoiding these moral dilemmas. (womens-health.co.uk)
  • Kilbride P, Meneghel J, Lamb S, Morris J, Pouzet J, Jurgielewicz M, Leonforte C, Gibson D, Madrigal A. Recovery and Post-Thaw Assessment of Human Umbilical Cord Blood Cryopreserved as Quality Control Segments and Bulk Samples. (anthonynolan.org)
  • They liken the process to that of cord blood banking - when parents freeze the blood from the umbilical cord of their babies. (syfy.com)
  • Umbilical cord blood carries an excess of stem cells and immune cells which could have therapeutic uses later in life. (syfy.com)
  • Stem cells from umbilical cords are usually used only in children because umbilical cord blood does not contain enough stem cells to use in adults. (msdmanuals.com)
  • Stem cells can be obtained from the blood in the umbilical cord or placenta after a baby is born. (msdmanuals.com)
  • These cells have been successfully used to treat children with blood cancers, such as leukemia, and certain genetic blood disorders. (healthline.com)
  • MSCs have been successfully transplanted in a number of disease models for which they have been shown to offer therapeutic benefits. (genengnews.com)
  • Last year, Hwang's team said it successfully cloned a human embryo from embryonic stem cells. (blogspot.com)
  • Yet further treatments using stem cells could potentially be developed due to their ability to repair extensive tissue damage. (wikipedia.org)
  • The implant may help treat several blood and immune disorders without the side effects of current treatments. (newscientist.com)
  • Stanford stem cell biologists have found a way to block a signal that causes growth of breast cancer cells, opening potential for new treatments. (stanford.edu)
  • Some monoclonal antibody treatments are designed to block signals that cancer cells use to grow. (ohsu.edu)
  • The developments utilizing adult stem cells, however, have been truly amazing with medical treatments (not mere potential or grand promises) already helping thousands of people. (blogspot.com)
  • The key to these cells' utility is their ability to differentiate into many different cell types depending on the stimulus received and they have been used in treatments for diseases such as cancer and neural degeneration, in rehabilitation of tetraplegic and paraplegic patients and even in dentistry 1 . (bvsalud.org)
  • In many cases, the cancer cells in children respond better to treatments compared to adults. (medlineplus.gov)
  • Since then, she has been in remission, and three years after the transplant she stopped using antiretroviral therapy and has been free of HIV for 14 months. (gcn.ie)
  • iPSCs are cells that have been genetically reprogrammed to an embryonic stem-cell-like state, meaning that they can differentiate into virtually any of the body's different cell types. (medindia.net)
  • It is an autoimmune disorder, where the body's immune system mistakenly attacks and destroys healthy cells in the pancreas. (diabetesresearch.org)
  • Blood stem cells reside in the bone marrow and produce all of the body's blood and immune cells. (healthcare-in-europe.com)
  • Tens of thousands of these procedures, often referred to as bone marrow transplants but more properly called hematopoietic stem cell transplants, are performed each year to rescue patients with immune system disorders or cancers. (sleepreviewmag.com)
  • While many scientists were studying genetic markers of cancer in people already diagnosed with the condition, the team had a very different question: Do the genetic mutations that drive the growth of leukemia and other blood cancers lurk in the bodies of people without cancer? (dana-farber.org)
  • Since the implant contributes to the host's blood supply, rather than replacing it altogether, it cannot be used to treat people who have blood cancers, who would still need to have their own bone marrow stem cells wiped out to cure the disease. (newscientist.com)
  • DNA methylation inhibitors already are under study at MCG and other centers for a variety of cancers and blood disorders. (sciencedaily.com)
  • Because tumor cells that result from aberrant changes shed their DNA into bodily fluids, non-invasive screening for a wide range of cancers could result be another result of this initiative, Dr. Bhalla says. (sciencedaily.com)
  • Adult stem cells are generally limited to differentiating into different cell types of their tissue of origin. (wikipedia.org)
  • They then use magnetic beads to separate about 500,000 stem cells out from the rest of the tissue. (extremetech.com)
  • Detection of the transplanted cells in the retina illustrated their ability to migrate from the site of injection to the injured tissue. (genengnews.com)
  • An innovative stem cell delivery method vastly improves the viability of tissue regenerating cells in animal spinal-cord injury models. (stanford.edu)
  • Emborg explains that although the results are encouraging overall, the authors report differences in dopamine production and innervation of the host tissue by the grafts, so it will be necessary to identify the best cell lines in order to improve replicability. (the-scientist.com)
  • Stem cells are the building blocks your body uses to repair damaged tissue. (growwithvitality.com)
  • These cells are classified as totipotent and they can form any of the tissue types found in the adult body, in addition to having unlimited proliferation potential 6 . (bvsalud.org)
  • Sickle-cell anemia is a disease of the blood marrow caused by a defect in a single gene. (medicalxpress.com)
  • IPS cells were selected based on their morphology and then verified to express gene markers specific to embryonic stem cells. (medicalxpress.com)
  • Drs Dick and Janska investigated the mouse strain in which transplanted human blood stem cells could engraft and develop that lead to the identification of the SIRPalpha gene - the one responsible for support of human blood cell engraftment and growth. (labcanada.com)
  • Recently, we learned that these tumors express a gene expression "signature" that causes recruitment and accumulation of immune cells to these tumors. (umn.edu)
  • We utilize genome-wide approaches to understand the altered gene expression and 5hmC distribution in retinal cells lacking the Uhrf2 gene. (umn.edu)
  • Retinoblastoma tumor cell proliferation is negatively associated with an immune gene expression signature and increased immune cells. (umn.edu)
  • These findings have led scientists to ask whether adult stem cells could be used for transplants. (news-medical.net)
  • These findings could serve for the design of less-invasive HIV cure strategies, since stem cell transplant is exclusively recommended in life-threatening haematological conditions. (biosstemcells.com)
  • The drugs also can't be used in patients with sickle cell disease. (popsci.com)
  • Current challenges and new approaches to implementing optimal management of sickle cell disease in sub-Saharan Africa. (cdc.gov)
  • If we could cure sickle cell disease in a safe and effective way, such as a pill that can reverse the disease, that would be a home run. (medlineplus.gov)
  • There are several types of stem cells that can be used for different purposes. (healthline.com)
  • There are basically two types of stem cells: embryonic and somatic (or adult). (bvsalud.org)
  • Certain kinds of adult stem cells seem to have the ability to differentiate into a number of different cell types, given the right conditions. (news-medical.net)
  • If something goes wrong, that often means relying on borrowing a microbiome jump start from a stranger by way of a fecal transplant. (syfy.com)
  • At the end of the day, a fecal transplant is one of those times when homemade is preferable to store bought. (syfy.com)
  • Only cells from an embryo at the morula stage or earlier are truly totipotent, meaning that they are able to form all cell types including placental cells. (wikipedia.org)
  • He says the structure could also offer a new way of studying blood stem cells and how blood disorders arise. (newscientist.com)
  • Niemann-Pick disease is a group of autosomal recessive disorders caused by an accumulation of fat and cholesterol in cells of the liver, spleen, bone marrow, lungs, and, in some instances, brain. (nih.gov)
  • This site provides information for patients and their families ranges from data about transplant outcomes to best practices in follow-up care for patients post-transplant. (myeloma.org)
  • Moreover, in one of the participants, viral antibodies fully disappeared 7 years post-transplant. (biosstemcells.com)
  • Describe factors associated with higher risk for HEV seroconversion and development of chronic disease among liver and kidney transplant patients. (cdc.gov)
  • According to Medical Xpress, a sleep deficit of just 4 hours can effect stem cells of the blood and immune system and reduce the efficiency of transplants. (sleepreviewmag.com)
  • Because stem cell transplants destroy and rebuild your immune system, they increase your risk for fungal infections. (cdc.gov)
  • In MS, the immune system cells that normally protect us from viruses, bacteria, and unhealthy cells mistakenly attack myelin in the central nervous system (brain, optic nerves, and spinal cord). (nih.gov)
  • Antiretroviral treatment is unable to cure HIV infection due to viral reservoir, consisting of HIV-infected cells that remain latent and cannot be detected and destroyed by the immune system. (biosstemcells.com)
  • Immunotherapies change how the immune system works so it can find and destroy cancer cells. (ohsu.edu)
  • It has long been known that C3 plays a crucial role for the immune system in the bloodstream where it helps white blood cells to engulf infectious microorganisms. (lu.se)
  • We kicked off the first ScienceBrew of 2024 with two great talks, covering the expansion of blood with nanotechnology and the possible role of immune system in limb regeneration. (lu.se)
  • The benefit of using MSCs in stem cell therapy is their ability to self-renew and differentiate into a variety of specialized cell types, such as osteoblasts, chondrocytes, adipocytes, myocardiocytes, and neuron-like cells. (genengnews.com)
  • This demonstrates that IPS cells have the same potential for therapy as embryonic stem cells, without the ethical and practical issues raised in creating embryonic stem cells," says Jaenisch. (medicalxpress.com)
  • OHSU was the first hospital in the Northwest to offer the CAR-T cell therapy Kymriah. (ohsu.edu)
  • In CAR T-cell therapy, some of the patient's T cells are collected from the patient's blood. (ohsu.edu)
  • Learn more about CAR T-cell therapy and our team's role in developing the first CAR T therapy approved by the FDA. (ohsu.edu)
  • A drug developed by US physician-scientists and chemists speeds up the regeneration of mouse and human blood stem cells after exposure to radiation. (healthcare-in-europe.com)
  • The study, published in Nature Communications , also sheds light on the basic biology behind blood stem cell regeneration and the role of a specific molecular process that is blocked by the new drug. (healthcare-in-europe.com)
  • They also are continuing to explore the mechanisms through which inhibiting PTP-sigma promotes the regeneration of blood stem cells. (healthcare-in-europe.com)
  • These mechanisms can malfunction in pediatric retinoblastoma, and may be harnessed during retinal regeneration to produce new retinal cell types after they've been lost. (umn.edu)
  • Stem Cells, Dentistry, Regeneration. (bvsalud.org)
  • Stem cells are nonspecific cells with powerful self-regeneration properties and they are capable of organizing other cell types in the body. (bvsalud.org)
  • But adult patients need two cords' worth of blood per treatment, and there aren't enough cord units available for everyone who needs the treatment. (scitechdaily.com)
  • Linheng Li believes that this approach could potentially be applied to other types of adult stem cells, which may lead to increasing the number of adult stem cells available for treating patients. (scitechdaily.com)
  • Some types of fungal infections are more common than others in stem cell transplant patients. (cdc.gov)
  • Aspergillosis is the most common type of fungal infection in stem cell transplant patients, followed by Candida infection and mucormycosis, but other types of fungal infections are also possible. (cdc.gov)
  • Some patients may benefit from blood tests to detect fungal infections like aspergillosis before symptoms appear. (cdc.gov)
  • Liver disease affects many people and, in a worst-case scenario, some patients require a liver transplant to survive. (slashgear.com)
  • Scientists are growing human hearts in laboratories, offering hope for millions of cardiac patients. (dailymail.co.uk)
  • Patients given normal heart transplants must take drugs to suppress their immune systems for the rest of their lives. (dailymail.co.uk)
  • The ghost hearts were then injected with millions of stem cells, which had been extracted from patients and supplied with nutrients. (dailymail.co.uk)
  • The previous cases of patients being cured of HIV occurred in two males who had received adult stem cells, which are more regularly used in bone marrow transplants. (gcn.ie)
  • About 1,000 patients to date have received this type of stem-cell transplant, known as a nonmyeloablative transplant. (fredhutch.org)
  • Mini-transplants can be used on older patients who are not in otherwise good medical condition, and can be done in the outpatient setting. (fredhutch.org)
  • Thanks to past advancements in medicine, patients are able to control their blood glucose levels with regular insulin injections or an insulin pump. (diabetesresearch.org)
  • We found no HEV reactivation among patients transplant recipients can lead to chronic hepatitis. (cdc.gov)
  • While it's not a cure, hydroxyurea helps red blood cells better carry oxygen in patients with moderate to severe SCD. (medlineplus.gov)
  • Stem cells can divide into two cells identical to the original stem cell or into differentiated cell types, depending on their origin and differentiation potency. (bvsalud.org)
  • By definition, adult stem cells are capable of differentiation into at least two lineages and have the property of self-renewal. (bvsalud.org)
  • However, the livers still worked as proven by human liver proteins found in the rats' blood serum. (slashgear.com)
  • Bone marrow cells could yield liver, muscle, neuron, and endothelium, while neurons could give rise to blood, and hepatocytes to pancreatic beta cells. (the-scientist.com)
  • Something you may be less familiar with, however, is the less-discussed practice of transplanting feces. (syfy.com)
  • Before Viagra made its money as a blockbuster erectile dysfunction drug, the medication was originally researched for its ability to dilate blood vessels. (popsci.com)
  • As a result, they decided to test Viagra, which opens blood vessels and increases their permeability. (popsci.com)
  • a short period of recovery sleep before transplant can restore the donor's cells' ability to function normally. (sleepreviewmag.com)