• Among 1462 patients who had allogeneic hematopoietic cell transplantation (HCT) between January 2000 and December 2005, 116 (7.9%) developed stage 3-4 gut GVHD. (nature.com)
  • An acute graft-versus-host disease activity index to predict survival after hematopoietic cell transplantation with myeloablative conditioning regimens. (nature.com)
  • Reduced mortality after allogeneic hematopoietic-cell transplantation. (nature.com)
  • To stimulate and facilitate further research, the NCI and NHLBI held the First International Consensus Conference on Late Effects after Pediatric Hematopoietic Cell Transplantation on April 28 and 29, 2011. (medscape.com)
  • Bone Marrow Transplantation is abstracted and indexed in BIOBASE/Current Awareness in Biological Sciences, BIOSIS, Current Contents/Clinical Medicine, Current Contents/Life Sciences, EMBASE/Excerpta Medica, MEDLINE/Index Medicus, and Science Citation Index. (wikipedia.org)
  • Prospective evaluation for upper gastrointestinal tract acute graft-versus-host disease after hematopoietic stem cell transplantation. (nature.com)
  • In addition to complications seen from exposure to chemotherapy and radiation, patients undergoing allogeneic transplantation can experience unique late effects secondary to graft versus host disease (GVHD) and autoimmunity. (medscape.com)
  • A short-chain fatty acid made by bacteria in the gut could play an important role in graft-versus-host disease (GVHD) after allogeneic bone marrow transplant in mice. (oncologynurseadvisor.com)
  • The percent of total CD3 + CD5 - cells correlated with the presence of graft versus host disease and with time following transplant, but did not correlate with age, diagnosis, preparative regimen, T-cell depletion of the marrow, major histocompatibility complex compatibility, or the presence or absence of interstitial pneumonitis. (mssm.edu)
  • Hu G, Liu P, Feng J, Jin Y. Transplantation with Bone Marrow Stromal Cells Promotes Wound Healing Under Chemotherapy through Altering Phenotypes. (ijbs.com)
  • While bone-marrow transplantation might mitigate hematopoietic syndrome, currently there are no approved medical countermeasures to alleviate radiation-induced gastrointestinal syndrome (RIGS), resulting from direct cytocidal effects on intestinal stem cells (ISC) and crypt stromal cells. (elsevierpure.com)
  • Conclusion/Significance: Mitigation of lethal intestinal injury, following high doses of irradiation, can be achieved by intravenous transplantation of marrow-derived stromal cells, including mesenchymal, endothelial and macrophage cell population. (elsevierpure.com)
  • Bone marrow is the spongy tissue inside some of your bones, such as your hip and thigh bones. (medlineplus.gov)
  • Bone marrow is a soft, spongy tissue found inside certain bones, responsible for producing blood cells. (globalstemcelltherapy.com)
  • Bone marrow is the fatty, spongy tissue in the bones. (umn.edu)
  • Pulmonary complications occur in half of allogeneic bone marrow transplantation (BMT) patients. (nih.gov)
  • While allogeneic transplantation can be life saving for patients with hematologic malignancies, or inherited disorders such as several forms of immuno-deficiency, the transplant-related side effects and complications remain the biggest hurdles. (stanford.edu)
  • If one of the brothers and sisters is compatible, we speak about geno-identical allogeneic transplantation having the advantage of reducing the complications post-transplantation. (longdom.org)
  • Treatment for this condition remains difficult and largely ineffective, because the growth of cells in the wound is inhibited ( 2 ) and chemotherapy usually leads to myelosuppression, the latter of which further compromises the migration of multipotent cells from the bone marrow ( 3 ). (ijbs.com)
  • Before chemotherapy medicines suppress the immune system, hematopoietic stem cells-which produce blood cells-that are generated from a person's bone marrow or blood are collected or kept. (bonemarrowtransplantations.com)
  • These may include additional chemotherapy, immunotherapy, targeted therapy, or even a second bone marrow transplant. (lifecancercenter.com)
  • The Thoracic Transplantation Committee of the Organ Procurement and Transplantation Network (OPTN) will be re-evaluating lung allocation policy as it applies to children during late 2013 and early 2014. (medindia.net)
  • Had a transplant such as organ, tissue, or bone marrow? (cdc.gov)
  • Bone marrow supersedes the liver as the major hematopoietic organ at 32-36 weeks' gestation. (medscape.com)
  • However, the virus can also be transmitted by transfusion of infected blood products or by solid organ transplantation. (cdc.gov)
  • In 2011, the CDC assisted state and local health departments in an investigation of a cluster of West Nile Virus disease transmitted through solid organ transplantation. (cdc.gov)
  • The true scale of the unmet need for organ transplantation is unknown in the African Region. (who.int)
  • https://en.wikipedia.org/wiki/Organ_transplantation. (who.int)
  • 5 United Nations General Assembly - Resolution A/RES/71/322 on Strengthening and promoting effective measures and international cooperation on organ donation and transplantation to prevent and combat trafficking in persons for the purpose of organ removal and trafficking in human organs, September 2017. (who.int)
  • Nonetheless, the weak regulatory frameworks are often unable to ensure the effective oversight needed for the implementation of quality and safety standards for organ transplantation. (who.int)
  • Persistent nausea and anorexia after marrow transplantation: a prospective study of 78 patients. (nature.com)
  • [ 7 ] of 798 patients who survived more than 5 years after transplantation, 328 were children. (medscape.com)
  • [ 2 , 8 ] Survivors of bone marrow transplantation were more likely to have a severe or life threatening condition (relative risk [RR] = 3.9), more than one chronic condition (RR = 2.6), functional impairment (RR=3.5), and activity limitations (RR = 5.8) than conventionally treated patients. (medscape.com)
  • Determine the effect of sargramostim (GM-CSF) on the progression-free 1-year survival of patients with myelodysplastic syndrome who have undergone T-cell-depleted CD34+ augmented allogeneic bone marrow transplantation. (knowcancer.com)
  • Departmental bone marrow transplant services offer essential medical expertise and complementary services to patients with complex health conditions. (tasmc.org.il)
  • The BMT-CT program at Stanford performs autologous and allogeneic transplantations for over 450 patients each year. (stanford.edu)
  • Two patients presented with fever and nodular pulmonary infiltrates 9 and 6 months after marrow transplantation for leukemia. (psu.edu)
  • Intending to enhance the quality of life for patients and their families, the Center provides top-notch treatment facilities utilizing cutting-edge technology and cutting-edge medicines to treat the majority of complicated illnesses requiring allogeneic transplantation. (bonemarrowtransplantations.com)
  • The decision to proceed with transplantation hinges on a thorough assessment of patients' chances for successful results, along with a comprehensive understanding of therapy-related risks. (medistateinternational.com)
  • Our outpatient program allows patients undergoing bone marrow transplantation to remain home or stay at an outpatient facility instead of spending weeks in the hospital. (hopkinsmedicine.org)
  • Our clinic provides telemedicine services for patients undergoing bone marrow transplantation and transplant recipients. (hopkinsmedicine.org)
  • Decision analysis of allogeneic bone marrow transplantation versus immunosuppressive therapy for young adult patients with aplastic anemia. (bvsalud.org)
  • The risk of regretting transplantation was 17.5 percentage points (95% confidence interval, 5.5-29.7 percentage points) greater in patients who developed disease recurrence after HCT compared with patients who did not. (cdc.gov)
  • Conclusions: Among patients who underwent alloHCT and lived to 100 days, the majority did not report regretting their transplantation. (cdc.gov)
  • While these are the only reported cases of disseminated Acanthamoeba infection in marrow transplant recipients, a review of the literature suggests that this organism may be a new cause of opportunistic infections. (psu.edu)
  • Genomic DNA of a patient diagnosed with nonobstructive azoospermia and with the history of allogenic bone marrow transplantation from his sister due to chronic myeloid leukemia was isolated from peripheral blood in order to screen Y chromosome microdeletions. (istanbul.edu.tr)
  • Only a small fraction of the donor's bone marrow is aspirated, and this fraction is renewed within a few weeks. (oslo-universitetssykehus.no)
  • Eight weeks after the donor's death, skin samples that had been treated in cryopreservative solution containing an antibiotic and unprocessed fat, muscle, tendon, and bone samples, all of which had been stored frozen at -70° Celsius at a tissue bank, were transferred to CDC. (cdc.gov)
  • The Dana-Dwek Children's Hospital Pediatric Hemato-oncology and Bone Marrow Transplantation Department treats infants, children, and adolescents suffering from acute and chronic blood diseases and from malignant hematological and non-hematological disorders. (tasmc.org.il)
  • Welcome to the Blood and Marrow Transplantation & Cellular Therapy Division. (stanford.edu)
  • We are a nationally recognized center of excellence, fully accredited by the Foundation for the Accreditation of Cellular Therapy (FACT) and a proud member of the Blood and Marrow Transplant Clinical Trials Network of the National Cancer Institute. (stanford.edu)
  • Autologous and allogeneic bone marrow transplant procedures are most frequently used to treat blood disorders or cancers. (bonemarrowtransplantations.com)
  • Our multidisciplinary program collaborates with Johns Hopkins Sidney Kimmel Comprehensive Cancer Center and Children's Center to potentially cure children with a variety of cancers and other disorders of the blood, immune system and bone marrow. (hopkinsmedicine.org)
  • In Norway new bone marrow donors are only recruited among blood donors. (oslo-universitetssykehus.no)
  • The bone marrow, which looks like blood, is aspirated through the needle to be collected in a transfusion bag. (oslo-universitetssykehus.no)
  • Methods Center for International Blood and Marrow Transplant Research data from 184 adults who completed the Functional Assessment of Cancer Therapy-Bone Marrow Transplant (FACT-BMT) before undergoing alloHCT and at day 100 were used. (cdc.gov)
  • Both types of bone marrow are highly vascular, being enriched with numerous blood vessels and capillaries. (medscape.com)
  • If a person experiences serious blood loss, yellow bone marrow can be activated and transformed into red bone marrow. (medscape.com)
  • Transplantation of enriched myeloid and non-myeloid fractions failed to improve survival. (elsevierpure.com)
  • Bone marrow, also known as myeloid tissue, are soft, spongy and gelatinous tissues inside the interior of bones. (healingtouristry.com)
  • The present report describes an incomplete atypical femoral fracture (AFF) patient who underwent simultaneous autogenous bone transplantation to the resected fracture region during intramedullary nail fixation. (hindawi.com)
  • To the best of our knowledge, this is the first report in which autogenous bone marrow transplantation, noninvasive to the iliac crest, was performed in an incomplete AFF patient. (hindawi.com)
  • A patient needs to stay in the hospital for four weeks and take precautions to get the best result from the transplantation. (bonemarrowtransplantations.com)
  • Measurements of serum erythropoietin and thrombopoietin levels, bone marrow electron microscopy, and megakaryocytic colony were grown for each patient in addition to DNA amplification and single-strand conformation polymorphism of each exon of the NF-E2, Fli-1, FOG-1, and Gfi-1b in genes. (bgu.ac.il)
  • Before transplantation, the patient received ciprofloxacin and ceftriaxone for bacteremia related to a colonized ventricular assist device. (cdc.gov)
  • Researchers also discovered that exposure to radiation, which many people experienced during the war, led to bone marrow failure or death. (umn.edu)
  • In the 1950s, researchers experimented with bone marrow grafts in animals exposed to radiation. (umn.edu)
  • Bone marrow first appears in the clavicle near the end of fetal life and becomes active about 3 weeks later. (medscape.com)
  • Fred Hutchinson Cancer Research Center bone marrow transplantation program, in partnership with the Seattle Cancer Care Alliance (SCCA), is the largest program in the world. (dnatube.com)
  • Dr. Appelbaum is the Executive Vice President and Clinical Research Professor at Fred Hutch Cancer Center (Seattle, WA) and author of " Living Medicine: Don Thomas, Marrow Transplantation, and the Cell Therapy Revolution " (2023). (iwmf.com)
  • Bone Marrow Transplantation is a common therapy to cure some forms of cancer and other diseases. (hopkinsmedicine.org)
  • At 7 months after surgery, radiographs demonstrated complete bone repair, and no clinical problems were observed two years postoperatively. (hindawi.com)
  • Bone marrow is the soft, fatty tissue inside your bones. (globalstemcelltherapy.com)
  • Bone marrow occupies the interior cavities of bones. (oslo-universitetssykehus.no)
  • Bone marrow is the soft, spongy, gelatinous tissue found in the hollow spaces in the interior of bones. (medscape.com)
  • Yellow marrow is found in the hollow interior of the diaphyseal portion or the shaft of long bones. (medscape.com)
  • These diseases can variably impact different bodily systems, from skeletal (bone, cartilage, joint) disorders to progressive neurological symptoms. (medistateinternational.com)
  • Results of IHC staining of skin, fat, muscle, and bone marrow samples were negative for West Nile Virus antigens. (cdc.gov)
  • Although high-dose chemoradiotherapy used for conditioning prior to autologous bone marrow transplantation (BMT) represent an effective tool for eradication of certain malignant hematological disorders, relapses indicate that the last tumor cell is unlikely to be completely eradicated. (tau.ac.il)