AllogeneicSolid organPancreasRecipientsChronicTissueRenalHematopoieticTransplantsCorneaCell TransplantationMarrow TransplantationPediatric TransplantationPatientsTissuesComplications2017RecipientABSTRACTOutcomesCancersMelanocyteDialysisLiver diseaseGraftTherapeuticsSimultaneousImmuneRegistryPatient'sMetabolicLesionsGraftsIncidenceSeverePatientCutaneousPigmentationPulmonaryLung diseaseFacialMortalitySignificantly
Allogeneic29
- This phase I trial assessed the safety, efficacy, and immunologic responses to minor histocompatibility antigens following nonmyeloablative allogeneic hematopoietic cell transplantation as treatment for metastatic renal cell carcinoma. (aacrjournals.org)
- Treatment of metastatic renal cell carcinoma with allogeneic hematopoietic cell transplantation after nonmyeloablative conditioning with fludarabine/total body irradiation is feasible and may induce tumor regression or stabilization in some patients. (aacrjournals.org)
- Allogeneic pancreas islet transplantation involves isolating islet cells from the pancreas of a cadaver donor, which are then purified and transplanted into the recipient via the portal vein or one of the tributaries of the liver where they take up residence and resume function. (bcbsnd.com)
- The BMT-CT program at Stanford performs autologous and allogeneic transplantations for over 450 patients each year. (stanford.edu)
- While the graft-versus-tumor effect provided by the donor graft can be very powerful in controlling the disease, disease relapse is still the primary reason that patients do not do well after an allogeneic transplantation. (stanford.edu)
- While allogeneic transplantation can be life saving for patients with hematologic malignancies, or inherited disorders such as several forms of immuno-deficiency, the transplant-related side effects and complications remain the biggest hurdles. (stanford.edu)
- First, given the utmost patient specificity and sensiyivity, it can be used to predict clinical outcome after allogeneic transplantation. (stanford.edu)
- Approximately 50% of the patients achieved molecular remission in both skin and blood compartments after allogeneic transplant while the other 50% had persistent MRD detected by HTS. (stanford.edu)
- Allogeneic stem cell transplantation uses donor stem cells to treat and sometimes cure certain blood disorders and blood cancers. (clevelandclinic.org)
- Providers may recommend allogeneic stem cell transplantation if initial treatments didn't work or treatments worked but the condition has come back. (clevelandclinic.org)
- In allogeneic stem cell transplantation, healthcare providers replace unhealthy stem cells with donated healthy stem cells. (clevelandclinic.org)
- What's the difference between allogeneic and autologous stem cell transplantations? (clevelandclinic.org)
- Allogeneic stem cell transplantation uses donated stem cells. (clevelandclinic.org)
- While both treatments help your bone marrow to develop new blood cells, studies show allogeneic stem cell transplantations work by causing the donor cells to attack unhealthy cells. (clevelandclinic.org)
- What cancers are treated with allogeneic stem cell transplantation? (clevelandclinic.org)
- People in remission from AML may be candidates for allogeneic stem cell transplantation. (clevelandclinic.org)
- Healthcare providers may recommend allogeneic stem cell transplantation for severe forms of aplastic anemia. (clevelandclinic.org)
- Providers may use allogeneic stem cell transplantation to treat severe forms of thalassemia. (clevelandclinic.org)
- Providers may use allogeneic stem cell transplantation if other treatments aren't successful. (clevelandclinic.org)
- Allogeneic stem cell transplantation may cure some blood disorders FA causes. (clevelandclinic.org)
- Allogeneic stem cell transplantation replaces damaged white blood cells. (clevelandclinic.org)
- Allogeneic stem cell transplantation treats the recurring and life-threatening infections this condition causes. (clevelandclinic.org)
- Who is a candidate for allogeneic stem cell transplantation? (clevelandclinic.org)
- Healthcare providers consider several factors before recommending allogeneic stem cell transplantation to treat blood disorders or cancer. (clevelandclinic.org)
- Not all cancers or blood diseases respond to stem cell transplantation, including allogeneic stem cell transplantation. (clevelandclinic.org)
- What makes a good match for an allogeneic stem cell transplantation? (clevelandclinic.org)
- Although it is possible to expand naturally occurring T(regs), an attractive alternative possibility, particularly suited to solid organ and bone marrow transplantation, is the stimulation of total T cell populations with defined allogeneic antigen-presenting cells (APCs) under conditions that lead to the generation or expansion of donor-reactive, adaptive T(regs). (lu.se)
- Chronic graft versus host disease (cGVHD) is the most common consequence of allogeneic bone marrow transplantation, and it is associated with morbidity and mortality. (bvsalud.org)
- Over past four months after allogeneic BTM she developed cGVHD in eyes, mouth, liver, lungs and skin. (bvsalud.org)
Solid organ5
- Over the last several decades, the field of solid organ transplantation (SOT) science and practice has advanced significantly, only to be continually challenged by the risks for infection in SOT recipients. (medscape.com)
- As a result, practitioners are challenged to help solid organ transplantation (SOT) recipients retain their transplanted organs, prevent SOT-related infections, and improve their quality of life. (medscape.com)
- This investigation documents F. tularensis transmission by solid organ transplantation. (cdc.gov)
- Kidney Transplantation Kidney transplantation is the most common type of solid organ transplantation. (merckmanuals.com)
- The transmission of rabies virus through cornea transplantation has been described, but transmission through solid organ transplantation was not recognized before 2004. (cdc.gov)
Pancreas7
- Pancreas transplantation is a type of surgery in which you receive a healthy donor pancreas. (hopkinsmedicine.org)
- Candidates for pancreas transplantation generally have type 1 diabetes, usually along with kidney damage, nerve damage, eye problems, or another complication of the disease. (hopkinsmedicine.org)
- Autologous pancreas islet transplantation is performed during the pancreatectomy procedure. (bcbsnd.com)
- Autologous pancreas islet transplantation may be considered medically necessary as an adjunct to a total or near total pancreatectomy in individuals with chronic pancreatitis. (bcbsnd.com)
- Autologous pancreas islet transplantation not meeting the criteria indicated in this policy is considered not medically necessary. (bcbsnd.com)
- Pancreas Transplantation Pancreas transplantation is a form of pancreatic beta-cell replacement that can restore normoglycemia in diabetic patients. (merckmanuals.com)
- The global and regional markets (except the US) for 'Organ and Tissue Transplantation' in this report are analyzed by the following Product Segments - Organ Tranplantation (Heart, Kidneys, Liver, Pancreas, and Lungs). (prnewswire.com)
Recipients8
- Keywords: Uremic osteodystrophy Bone loss Fracture Kidney transplantation INTRODUCTION Metabolic bone diseases in kidney transplant recipients may include pre-existing uremic osteodystrophy osteoporosis bone fracture osteonecrosis and bone pain syndrome. (exposed-skin-care.net)
- The September 2019 issue of the American Journal of Transplantation contains a comprehensive review of the various topics within the scope of infections in SOT recipients. (medscape.com)
- Mold Infections After Organ Transplant From Drowned Donors The transplantation of organs from drowned organ donors could cause fatal invasive mold infections in transplant recipients. (medscape.com)
- Iron Deficiency and Cognition After Kidney Transplantation Could iron deficiency treatment help restore cognitive function among kidney transplant recipients? (medscape.com)
- The OPTN brings together medical professionals, transplant recipients and donor families to develop organ transplantation policy. (unos.org)
- Whilst quality of life should be considered in all potential recipients, it is currently unlikely that transplantation would be offered solely for this reason due to the shortage of available donor organs. (ersjournals.com)
- In May 2010, the Sixty-third World Health Assembly adopted resolution WHA63.22,1 in which it endorsed the updated WHO Guiding Principles on Human Cell, Tissue and Organ Transplantation and provided strategic directions to support progress in human organ, tissue and cell donation with the aim of maximizing the benefits of transplantation, meeting the needs of recipients, protecting donors and ensuring the dignity of all involved. (who.int)
- Corneal disease (scarring or perforation) can be successfully addressed through transplantation in 80% of affected individuals.3 Tissue transplantation allows many recipients to return to economically productive lives and promotes their independence. (who.int)
Chronic7
- Full-thickness skin defects are mainly represented by acute carcinologic excisions, donor-site scarring of reconstructive procedures, burn injuries, and traumatic and chronic wounds. (frontiersin.org)
- A secondary advantage is that islet cell transplantation appears to help maintain normoglycemia in patients who require total pancreatectomy for pain due to chronic pancreatitis. (merckmanuals.com)
- Lung transplantation should be viewed as a potential treatment option for highly selected patients with very advanced chronic lung disease who continue to progress despite maximal medical therapy. (ersjournals.com)
- The benefits of human tissue transplantation can be seen in both children and adults, including in survival rates following severe burn trauma, recovery of movement, closure of chronic wounds, rehabilitation of heart function and restoration of sight. (who.int)
- Organ transplantation is often the best, if not the only, treatment for acute and chronic organ failure. (who.int)
- For chronic or acute liver failure, as well as some cardiorespiratory conditions, the only alternative to transplantation is death. (who.int)
- Psoriasis is considered an incurable, long-term (chronic) inflammatory skin condition. (medicinenet.com)
Tissue10
- Biotechnology and tissue engineering methods lead to the use of skin cell cultures, taken from the patient s healthy skin areas and expanded to cell sheets in Petri dishes. (technovelgy.com)
- Use of the connective tissue skin fibroblast cells additionally and in parallel to skin keratinocytes, allowing better tissue reorganization in the wound (cell biology approach). (technovelgy.com)
- VCAs involve the transplantation of multiple structures that may include skin, bone, muscles, blood vessels, nerves and connective tissue. (unos.org)
- eg, bone, bone marrow, and skin grafts) Genetically identical (syngeneic [between monozygotic twins]) donor tissue (isografts) Genetically. (merckmanuals.com)
- http://www.researchandmarkets.com/research/f7thqr/organ_and_tissue ) has announced the addition of the "Organ and Tissue Transplantation - Global Strategic Business Report" report to their offering. (prnewswire.com)
- This report analyzes the worldwide markets for Organ and Tissue Transplantation in Number of Procedures. (prnewswire.com)
- For these infections, the initial link to the transplanted organ was made by histopathologic evaluation and immunohistochemical testing of tissue from an organ recipient who died 4 weeks after undergoing transplantation. (cdc.gov)
- Tissue transplantation is the removal of various tissues, such as skin cells, corneas, cartilage, or bone, from a body and then inserting that tissue into the same or another person who has a serious disorder affecting some of that type of tissue. (msdmanuals.com)
- The amount of skin available for grafting may be increased by growing small pieces of the person's skin in a tissue culture or by making many tiny cuts in the grafted skin, so that it can be stretched to cover a much larger area. (msdmanuals.com)
- Lung tissue specimens from the employees, obtained by lung biopsy or at the time of lung transplantation, were reviewed by five pulmonary pathologists at three different institutions. (cdc.gov)
Renal4
- Renal transplantation is the most common organ transplantation procedure in Indonesia . (bvsalud.org)
- To compare the incidence of cancer in patients receiving immune suppression after kidney transplantation with incidence in the same population in 2 periods before receipt of immune suppression: during dialysis and during end-stage kidney disease before renal replacement therapy (RRT). (nih.gov)
- The primary indication for kidney transplantation is End-stage renal failure. (merckmanuals.com)
- Polygenic risk score as a determinant of risk of non-melanoma skin cancer in a European-descent renal transplant cohort. (cdc.gov)
Hematopoietic3
- Eight patients received conditioning with fludarabine and low-dose total body irradiation followed by hematopoietic cell transplantation from an HLA-matched sibling donor. (aacrjournals.org)
- Hematopoietic stem cell transplantation (HSCT) has been shown to be effective. (medscape.com)
- Hematopoietic stem cell transplantation (HSCT) is a broad term that covers the transplantation of blood progenitor/stem cells from any source. (drugdiscoverynews.com)
Transplants1
- Composite transplants may include skin, muscle, bone, and tissues that connect and support these structures. (msdmanuals.com)
Cornea1
- Outcomes of corneal transplantation in Europe: report by the European Cornea and Cell Transplantation Registry. (who.int)
Cell Transplantation6
- Transplanting their own (autologous) bone marrow-derived stem cells into 48 patients with end-stage liver disease resulted in therapeutic benefit to a high number of the patients, report researchers publishing in the current issue of Cell Transplantation (19:11). (medicaldaily.com)
- In the prospective Autologous Stem Cell Transplantation International Scleroderma (ASTIS) trial, a phase 3 comparison of autologous HSCT with 12 successive monthly intravenous pulses of cyclophosphamide in 156 patients with early diffuse cutaneous systemic sclerosis, HCST was associated with higher treatment-related mortality than in the first year after treatment. (medscape.com)
- Healthcare providers typically recommend stem cell transplantation if initial treatments don't work or if conditions have come back. (clevelandclinic.org)
- About 50% of people who need stem cell transplantation use stem cells donated by someone who's not a family member. (clevelandclinic.org)
- An autologous stem cell transplantation uses your own blood stem cells. (clevelandclinic.org)
- For example, people who have stem cell transplantation go through intensive chemotherapy before treatment. (clevelandclinic.org)
Marrow Transplantation2
- To the best of our knowledge, this is the first report in which autogenous bone marrow transplantation, noninvasive to the iliac crest, was performed in an incomplete AFF patient. (hindawi.com)
- Welcome to the Blood and Marrow Transplantation & Cellular Therapy Division. (stanford.edu)
Pediatric Transplantation1
- Challenges after pediatric transplantation. (medscape.com)
Patients18
- 'Using such bioimplant makes it possible to restore the skin integument lost due to deep burns, severe injuries, and cicatricial deformities, whereas standard transplantation with the use of free skin from hands, face or joints leads to scars, thus deteriorating the quality of the patients' life' , - he pointed out. (russia-ic.com)
- Does Transplantation Induce Aging In Patients? (medicaldaily.com)
- Around 40% of cancers in RTR patients were non- melanoma skin cancer (NMSC). (bvsalud.org)
- Carey, E.J., Gautam, M., Ingall, T. and Douglas, D.D. (2008) The Effect of Liver Transplantation on Autonomic Dysfunction in Patients with End-Stage Liver Disease. (scirp.org)
- Fleisher, L.A., Fleckenstein, J.F., Frank, S.M. and Thuluvath, P.J. (2000) Heart Rate Variability as a Predictor of Autonomic Dysfunction in Patients Awaiting Liver Transplantation. (scirp.org)
- Vitiligo is an acquired skin disease that significantly impacts the quality of life of patients. (cun.es)
- Twelve patients got skin vesicles because of contact with micropore over the skin of the ankles. (liposuction.com)
- We treated those patients with local antibiotics, obtaining healing of the skin in about 5 days, with dryness and absence of the vesicles. (liposuction.com)
- Here, we studied skin and gut microbiota of vitiligo patients compared to healthy controls. (medrxiv.org)
- Improvements in immune-modulating therapy, critical care medicine, and surgical techniques have led to the increased success of organ transplantations, and more patients are now eligible for these procedures. (cdc.gov)
- Summary Over the last 25 years, lung transplantation has developed into a well-established treatment option for selected patients with very advanced lung disease. (ersjournals.com)
- Patients who lose 10% or more of their body weight from the time of their listing on a transplant waiting list are at higher risk of death following deceased-donor kidney transplantation. (renalandurologynews.com)
- The self-esteem and quality of life of patients with psoriasis are often diminished because of the appearance of their skin. (medicinenet.com)
- Le pourcentage de CD44 dans les lymphocytes T périphériques était significativement plus élevé chez les patients que chez les témoins, comme détecté par la cytométrie en flux. (who.int)
- En outre, il y avait une aug- mentation significative de la forme soluble du c-kit dans le sérum des patients atteints de pemphigus vulgaire actif par rapport aux témoins. (who.int)
- However, assessment of malnutrition in patients with liver cirrhosis before transplantation cannot rely completely on these tests because the proteins are produced in the liver. (medscape.com)
- These patients may need parathyroidectomy before transplantation. (medscape.com)
- Body composition measurements have been used to assess nutritional status in pediatric patients before and after liver transplantation. (medscape.com)
Tissues6
- In contrast to the child, the fetus has the ability to heal skin injury without scar formation, and instead with regeneration of epithelial and mesenchymal tissues and restoration of normal skin architecture. (nih.gov)
- The transplantation of human tissues, organs or cells is an established form of treatment that has been acknowledged as the best and very often only life-saving therapy for several serious and life-threatening congenital, inherited and acquired diseases and injuries. (who.int)
- Thus, the availability of and access to human tissues for transplantation remains essential. (who.int)
- In June 2018, the Secretariat established the WHO Task Force on Donation and Transplantation of Human Organs and Tissues as an advisory group composed of experts from all WHO regions. (who.int)
- Overview of Transplantation Transplantation is the removal of living, functioning cells, tissues, or organs from the body and then their transfer back into the same body or into a different body. (msdmanuals.com)
- Organ donation is the process of taking healthy organs and tissues from one person for transplantation into another. (cdc.gov)
Complications1
- The recipient, Richard Herrick, died eight years after the transplantation due to complications with the donor kidney that were unrelated to the transplant. (wikipedia.org)
20171
Recipient1
- Risk of Non-melanoma Skin Cancer in Kidney Transplantation Recipient: An Evidence-based Case Report. (bvsalud.org)
ABSTRACT1
- Fat Transplantation to the Buttocks and Legs for Aesthetic Enhancement Dermatologic Surgery Back to Choose a Journal Back to List of Articles 2000 Abstract 0012-1145 dePedroza de Pedroza LV. (liposuction.com)
Outcomes3
- eGFR With Creatinine and Kidney Transplant Outcomes Estimated glomerular filtration rate based on serum creatinine may better determine the risk for adverse outcomes after kidney transplantation. (medscape.com)
- Simultaneous islet cell-kidney transplantation may be desirable in the future after the outcomes have improved. (merckmanuals.com)
- Behavioral and Psychological Outcomes Associated with Skin Cancer Genetic Testing in Albuquerque Primary Care. (cdc.gov)
Cancers3
- Immune suppression after organ transplantation is associated with a markedly increased risk of nonmelanoma skin cancer and a few virus-associated cancers. (nih.gov)
- Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer and one of the most common cancers overall in the United States. (medscape.com)
- In a study of the US Medicare population, the treatment of nonmelanoma skin cancers ranked fifth among the most expensive cancers to treat in the head-and-neck region. (medscape.com)
Melanocyte1
- Rationale Vitiligo is an autoimmune-disease characterized by patchy, white skin due to melanocyte loss. (medrxiv.org)
Dialysis1
- Kidney transplantation is a far more favourable treatment modality versus dialysis in terms of survival, quality of life and cost-effectiveness. (who.int)
Liver disease1
- Conclusion: Infants with liver disease, even after transplantation, have delay in motor development, as well as changes in their nutritional and autonomic dysfunction. (scirp.org)
Graft3
- An autologous split-thickness skin graft (STSG) is a standard treatment for coverage of full-thickness skin defects. (frontiersin.org)
- An autologous split-thickness skin graft (STSG) is the reference treatment for skin coverage, especially when the defect is large and reaches the hypodermis. (frontiersin.org)
- A comprehensive review of the history of free fat transplantation reveals that since 1893 when Neuber used small pearls of fat taken from the arm to fill out depressed facial scars after trauma and underlying bone loss, free fat graft has been used with success in facial surgery, brain and nervous system surgery, various orthopedic uses, general surgery, craniofacial surgery, and cosmetic surgery. (liposuction.com)
Therapeutics1
- Regulatory T cells (T(regs)) manipulated ex vivo have potential as cellular therapeutics in autoimmunity and transplantation. (lu.se)
Simultaneous1
- The present report describes an incomplete atypical femoral fracture (AFF) patient who underwent simultaneous autogenous bone transplantation to the resected fracture region during intramedullary nail fixation. (hindawi.com)
Immune1
- Because SIRs for most types of cancer were not increased before transplantation, immune suppression may be responsible for the increased risk. (nih.gov)
Registry2
- Trends in Kidney Transplantation Rate Across Europe Data from the ERA registry provides insight into the trends in kidney transplantation rates in Europe. (medscape.com)
- In 2010, over a 12-month period, more than 3500 new lung transplant procedures were reported to the International Society of Heart and Lung Transplantation (ISHLT) Registry [ 1 ]. (ersjournals.com)
Patient's1
- Lung transplantation should generally be considered when a patient's risk of mortality from their lung disease is greater than 50% within the next 2 years. (ersjournals.com)
Metabolic1
- Although it is important to obtain bone densitometry (dual-energy x-ray absorptiometry (DEXA) scanning) before transplantation to assess the presence of metabolic bone disease in adults, it is of limited usefulness in children. (medscape.com)
Lesions3
- UVA1 inhibits the inflammatory process and can soften former sclerotic skin lesions. (medscape.com)
- When someone has mycosis fungoides, malignant cells in the blood travel to the skin, causing lesions that appear as an itchy rash. (stanford.edu)
- Other significant skin lesions are actinic keratosis and melanoma. (medscape.com)
Grafts2
- Skin grafts are considered a form of transplantation. (msdmanuals.com)
- Such grafts last only a short time, but they can provide temporary protection until normal skin grows to replace them. (msdmanuals.com)
Incidence2
- After transplantation, cancer occurred at significantly increased incidence at 25 sites, and risk exceeded 3-fold at 18 of these sites. (nih.gov)
- Despite increased knowledge and public education regarding the causes of skin cancer and modes of prevention, the incidence of cSCC continues to rise worldwide. (medscape.com)
Severe4
- Using such implant makes it possible to restore the skin integument lost due to deep burns, severe injuries, and cicatricial deformities. (russia-ic.com)
- According to Mr. Shevelin, doctors of A. M. Nikiforov All-Russian Center of Emergency and Radiation Medicine operated on a man who had suffered severe fire burns, and after standard skin transplantation his hands had lost considerable amount of movements because of scars. (russia-ic.com)
- The spectrum of this disease ranges from mild with limited involvement of small areas of skin to severe psoriasis with large, thick plaques to red inflamed skin affecting the entire body surface. (medicinenet.com)
- We identified four nonsmoking employees who had severe lung disease, including one employee who required lung transplantation. (cdc.gov)
Patient1
- The patient presented sclerotic skin changes, hyperkeratosis of hands and xerophthalmia. (bvsalud.org)
Cutaneous3
- Basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC) are the first and second most common types of skin cancer, respectively. (medscape.com)
- Conclusion These data describe vitiligo-specific cutaneous and gut microbiota and, for the first time in humans, a link between mitochondrial alteration, innate immunity and skin microbiota. (medrxiv.org)
- Expert Consensus on the Use of Prognostic Gene Expression Profiling Tests for the Management of Cutaneous Melanoma: Consensus from the Skin Cancer Prevention Working Group. (cdc.gov)
Pigmentation1
- The individuals can enhance their tan by darkening the pigmentation of their skin with tanning injections for sale. (ferraradancemotive.com)
Pulmonary2
- Lung transplantation is the only intervention that prolongs survival in idiopathic pulmonary fibrosis (IPF). (ersjournals.com)
- Idiopathic pulmonary fibrosis (IPF) is progressive and fatal, and lung transplantation is the only therapy that has been shown to prolong survival [ 1 ], [ 2 ]. (ersjournals.com)
Lung disease1
- To outline recent advances made in improving the success of lung transplantation as a therapy for very advanced lung disease. (ersjournals.com)
Facial2
- Although cSCC is not often fatal, it can cause significant morbidity, especially when it involves the facial skin. (medscape.com)
- Somatic mutations in facial skin from countries of contrasting skin cancer risk. (cdc.gov)
Mortality2
- The mortality rate for victims suffering from full thickness -3rd degree- burns is high, due to the limits in availability of healthy skin cell area. (technovelgy.com)
- Prior to this point, the peri-operative mortality risks of transplantation may outweigh the benefits. (ersjournals.com)
Significantly1
- The tan can significantly last for a longer time as your skin can progressively become darker with the help of Melanotan. (ferraradancemotive.com)