• Administration of cyclosporin after syngeneic bone marrow transplantation paradoxically elicits a T lymphocyte-dependent autoaggression syndrome termed syngeneic graft-vs-host disease (SGVHD). (johnshopkins.edu)
  • Our studies reveal that although cyclosporin did not interfere with the effector function of the autoregulatory T cells, it prevented the reconstitution of the regulatory system after syngeneic bone marrow transplantation. (johnshopkins.edu)
  • Syngeneic transplantation (also referred to as isogeneic or isologous transplantation) is the transplantation of cells, tissue or organs between genetically identical individuals. (drze.de)
  • METHODS: Normal-risk allogeneic (C57BL/6 to BALB/c) and syngeneic (BALB/c to BALB/c) corneal transplantations were performed and occurrence and time course of hem- and lymphangiogenesis after keratoplasty was observed, by using double immunofluorescence of corneal flatmounts (with CD31 as a panendothelial and LYVE-1 as a lymphatic vascular endothelium-specific marker). (ox.ac.uk)
  • Co-founder and first president of the American Society of Transplant Physicians (now called American Society of Transplantation. (wikipedia.org)
  • Transplantation between genetically identical individuals, i.e., members of the same species with identical histocompatibility antigens, such as monozygotic twins, members of the same inbred strain, or members of a hybrid population produced by crossing certain inbred strains. (lookformedical.com)
  • Usually refers to genetically disparate individuals in contradistinction to isogeneic transplantation for genetically identical individuals. (bvsalud.org)
  • Results: We performed seven orthotopic and four heterotopic transplantations. (bvsalud.org)
  • Six orthotopic and three heterotopic recipients survived up to 2รข h after transplantation. (bvsalud.org)
  • Modulation of the NO pathway during short or prolonged blood reperfusion following ischaemia in a heterotopic rat heart transplantation model. (ox.ac.uk)
  • Experiments were performed using a modified Lewis to Lewis heterotopic abdominal heart transplantation with a total ischemic time of 3 hours followed by 1 or 24 hours of blood reperfusion (n = 12). (ox.ac.uk)
  • Restoration of cutaneous pigmentation by transplantation to mice of isogeneic human melanocytes in dermal-epidermal engineered skin substitutes. (uc.edu)
  • Here, we describe the microsurgical technique of multivisceral transplantation of pelvic organs, including the pelvic floor, in rats. (bvsalud.org)
  • C6-sufficient and -deficient female PVG.1U (RT1.A u B u ) rats were mated with allogeneic PVG.R8 (RT1.A a B u ) males or control isogeneic PVG.1U (RT1.A u B u ) males. (johnshopkins.edu)
  • No immunosuppressed isogeneic (ISO) and allogeneic (ALO) rats mixture offered as control. (pkc-inhibitor.com)
  • Background: Multivisceral transplantation of pelvic organs would be a potential treatment for severe pelvic floor dysfunction with fecal and urinary incontinence, extensive perineal trauma, or congenital disorders. (bvsalud.org)
  • RESULTS: No blood or lymph vessels were detectable immediately after normal-risk transplantation in either donor or host cornea, but hem- and lymphangiogenesis were clearly visible at day 3 after transplantation. (ox.ac.uk)
  • Unfortunately for children in need of heart (or valve) transplantation, there are small numbers of donor hearts available. (savingtinyhearts.org)
  • Bottom line Both immunosuppressed protocols with tacrolimus (administration from time 1 or from time 7 pursuing transplantation) could actually suppress severe cell- and antibody-mediated rejection of cryopreserved abdominal aortic allografts prepared relative to our brand-new standardized scientific protocol. (pkc-inhibitor.com)
  • This study focused on the comparison of autologous and allogeneic immune response to iPSC-derived cells and isogeneic parental somatic cells used for reprogramming. (biomedcentral.com)
  • Transplantation between individuals of the same species. (bvsalud.org)
  • We observed that iPS-fibro elicited a high level of NK-cell degranulation and cytotoxicity, while isogeneic parental skin fibroblasts used to obtain iPSCs barely triggered an NK-cell response. (biomedcentral.com)
  • We established an isogeneic cell model consisting of parental dermal fibroblasts, fibroblast-like iPSC-derivatives (iPS-fibro) and iPS-fibro lacking beta-2-microglobulin (B2M). (biomedcentral.com)
  • Finally, we will transplant the recellularized constructs into isogeneic animals, and evaluate for left ventricular pressure, ejection fraction, central and peripheral pressures, graft perfusion and bleeding of the neomyocardial LV hetero graft. (savingtinyhearts.org)
  • Allogeneic, but not control isogeneic, pregnancy elicited a weak, transient IgG alloantibody response that declined before transplantation. (johnshopkins.edu)
  • Aortal wall structure infiltration by immunocompetent cells (MHC II+ cells of recipient origins) was analyzed on time 30 after transplantation. (pkc-inhibitor.com)
  • In 1969, he was appointed associate in medicine at the Peter Bent Brigham Hospital and instructor in medicine at Harvard Medical School, and permanently moved to Montreal, Canada in 1970 to become director of the transplantation service at the Royal Victoria Hospital and McGill University Clinic and associate professor of medicine, McGill University Faculty of Medicine. (wikipedia.org)
  • Furthermore, we confirmed a chance of delaying the administration of low-dose tacrolimus after an arterial transplantation for a week without any detrimental impact on both types of rejection [14]. (pkc-inhibitor.com)