Kidney transplantationOrganIslet cell transplantAllergyHematopoietic-Cell TransplantationBlood and Marrow TransplantationStem-cell transplantTissueClinical transplantationLiving-donorNephrologyFrontiers in ImmunologyField of transplantationHeart transplantationAutoimmuneOutcomeToleranceImmunePatient'sPancreasMilanInflammationAutologousRegulatoryOutcomesImmunosuppressionResearchTransplantsPost-transplantBonePediatricClinicallyUniversityCancer
Kidney transplantation13
- Kidney Transplantation Kidney transplantation is the most common type of solid organ transplantation. (merckmanuals.com)
- The primary indication for kidney transplantation is End-stage renal failure. (merckmanuals.com)
- Simultaneous islet cell-kidney transplantation may be desirable in the future after the outcomes have improved. (merckmanuals.com)
- Disadvantages to the donor include mortality risk of 1/600 to 700 (compared with 1/3300 in living-donor kidney transplantation) and complications (eg, bile leakage, bleeding) in up to one fourth. (msdmanuals.com)
- Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials. (charite.de)
- The aim of the present report is to examine the outcome of pregnancies under tacrolimus after kidney transplantation (KTx) and simultaneous kidney-pancreas transplantation (SPKTx). (nih.gov)
- To compare the incidence of cancer in patients receiving immune suppression after kidney transplantation with incidence in the same population in 2 periods before receipt of immune suppression: during dialysis and during end-stage kidney disease before renal replacement therapy (RRT). (nih.gov)
- Kidney transplantation is associated with a marked increase in cancer risk at a wide variety of sites. (nih.gov)
- Dr. Kulkarni specializes in liver transplantation, kidney transplantation, pancreas transplantation and laparopscopic living donor nephrectomy. (medscape.com)
- His team will collaborate on articles focused on liver and kidney transplantation on Medscape. (medscape.com)
- S2 Episode 5: When Is It Time to Talk About Kidney Transplantation? (medscape.com)
- Today we'll be discussing kidney transplantation with my guest, Dr Samira Farouk. (medscape.com)
- For example, we might take care of somebody with a pulmonary embolism soon after kidney transplantation or somebody who's many years out from their transplant having an opportunistic infection or experiencing an acute rejection of their transplant. (medscape.com)
Organ11
- Furthermore, principles learned from the study of whole organ transplantation may find application in the emerging field of regenerative medicine, in which the use of immune suppression is likely to be contraindicated. (ox.ac.uk)
- Develop insights into immunosurveillance and how cancer and organ transplantation overcome immune responses. (sfu.ca)
- Immune suppression after organ transplantation is associated with a markedly increased risk of nonmelanoma skin cancer and a few virus-associated cancers. (nih.gov)
- Transplantation Laboratory has been organising Principles of organ transplantation course every other year from 2005 onwards for medical students, nurses, and registrars. (helsinki.fi)
- Find here the program of the Principles of organ transplantation 2016 course in Finnish. (helsinki.fi)
- Renkonen R, Lemström K, Mäkisalo H. Organ and tissue transplantation, In the textbook of Immunology: microbiology, immunology, and infectious diseases (In Finnish: Elin- ja kudossiirrot, Immunologia: mikrobiologia, immunologia ja infektiosairaudet). (helsinki.fi)
- His postdoctoral training was performed on minor H antigens in organ- and stem-cell transplantation in the laboratory of Prof. Dr. Els Goulmy, Leiden, The Netherlands. (umcutrecht.nl)
- Induction of immunologic tolerance has been achieved and studied in numerous laboratory animal models, but it remains an elusive goal in clinical organ transplantation and in the management of autoimmune disease in humans. (medscape.com)
- Transplantation is the most effective treatment for end-stage organ failure, but organ survival is limited by immune rejection and the side effects of immunosuppressive regimens. (lu.se)
- Organ and tissue transplantation in the European union : management of difficulties and health risks linked to donors / edited by Yvon Englert. (who.int)
- Legislative responses to organ transplantation / edited by World Health Organization. (who.int)
Islet cell transplant1
- A secondary advantage is that islet cell transplantation appears to help maintain normoglycemia in patients who require total pancreatectomy for pain due to chronic pancreatitis. (merckmanuals.com)
Allergy1
- Journal of Allergy and Clinical Immunology. (lu.se)
Hematopoietic-Cell Transplantation1
- Relapse and graft- versus -host disease (GvHD) are the main impediments to the clinical success of allogeneic hematopoietic cell transplantation (HCT) in curing malignant blood disorders. (haematologica.org)
Blood and Marrow Transplantation1
- We tested this novel hypothesis in over 6,000 HCT from 8/8 HLA-matched UD reported to the European Group for Blood and Marrow Transplantation (EBMT), to demonstrate that HLA-DPB1 non-TPHE mismatches were associated with worse relapse-free survival and overall survival than TPHE mismatches, present in 21.7% of single HLA-DPB1 disparate pairs. (haematologica.org)
Stem-cell transplant1
- Mannose-binding lectin gene variants and infections in patients receiving autologous stem cell transplantation. (cdc.gov)
Tissue3
- With the use of tissue typing and anti-rejection drugs, transplantation of organs and the control of the anti-transplant immune response have made huge strides in the past 50 years. (openstax.org)
- Tissue transplantation is more complicated than blood transfusions because of two characteristics of MHC molecules. (openstax.org)
- They determine tissue type for transplantation and cause allograft rejections. (bvsalud.org)
Clinical transplantation2
- On reflection of the worldwide transplants, Stinson stated Many centers took up clinical transplantation without the laboratory experience or profound support in clinically related areas such as immunosuppression. (wikipedia.org)
- Nonetheless, immune tolerance remains the holy grail of transplantation immunology and clinical transplantation. (medscape.com)
Living-donor1
- Dr. Emre and his team have collaborated on topics such as living donor liver transplantation, and pediatric liver transplantation on Medscape, an area of expertise at Yale. (medscape.com)
Nephrology2
- The second was nephrology and the third was immunology, which was a new concept to me at the time. (medscape.com)
- Obviously, you love nephrology and transplantation. (medscape.com)
Frontiers in Immunology3
- Betjes Michiel G.H., Peereboom Emma T.M., Otten Henny G., Spierings Eric 30 Aug 2022, In: Frontiers in Immunology. (umcutrecht.nl)
- Niemann Matthias, Matern Benedict M, Spierings Eric 29 Jul 2022, In: Frontiers in Immunology. (umcutrecht.nl)
- Frontiers in Immunology. (lu.se)
Field of transplantation2
- [ 3 ] Seemingly impossible without genetic identity, the field of transplantation was left silent for another 20 years. (medscape.com)
- Long-term transplant acceptance in the absence of immunosuppressive therapy remains the ultimate goal in the field of transplantation and many studies are exploring potential therapies. (lu.se)
Heart transplantation6
- Edward B. Stinson (born 1938) is an American retired cardiothoracic surgeon living in Los Altos, United States, who assisted Norman Shumway in America's first adult human-to-human heart transplantation on 6 January 1968 at Stanford University. (wikipedia.org)
- For over twenty years, Stinson was the principal investigator for the National Institutes of Health programme project in heart transplantation at Stanford. (wikipedia.org)
- As staff associate, he was responsible for both clinical activity in cardiac surgery in the Clinic of Surgery of the National Heart Lung and Blood Institute and for intramural research programs addressing cardiac physiology and heart transplantation. (wikipedia.org)
- In late 1980, he was part of the team that first introduced the anti-rejection drug cyclosporine for heart transplantation. (wikipedia.org)
- Lemström K, Lommi J. Heart failure - surgical treatment and heart transplantation. (helsinki.fi)
- Lemström K. Heart transplantation and mechanical circulatory support and lung and heart-lung transplantation. (helsinki.fi)
Autoimmune2
- Ye is a Professor of Autoimmune liver diseases and Translational Hepatology at the Institute of Immunology and Immunotherapy, University of Birmingham and Consultant Hepatologist at the Queen Elizabeth Hospital where he specialises in the management of autoimmune liver diseases, immune mediated liver injury and liver transplantation. (birmingham.ac.uk)
- During his PhD he dissected the recruitment mechanism of regulatory T cells and developed isolation of GMP-grade regulatory T cells to apply as new therapy in autoimmune liver diseases and liver transplantation. (birmingham.ac.uk)
Outcome1
- It takes advantage of combining data from all transplant programmes in one unique system to perform comprehensive nationwide reporting and to promote translational and clinical post-transplant outcome research in the framework of Swiss transplantation medicine. (bmj.com)
Tolerance3
- Harnessing dendritic cells for the induction of transplantation tolerance. (ox.ac.uk)
- A translational research group focused on developing novel immunomodulatory therapies to ameliorate inflammation and induce immunological tolerance in liver diseases and transplantation. (kcl.ac.uk)
- Transplantation tolerance could eliminate many of the adverse events associated with immunosuppressive agents. (medscape.com)
Immune3
- Before transplantation, patients showed altered immune cell composition, and regulatory cells were better than standard therapy at restoring normal composition," explains Prof. Sawitzki. (charite.de)
- Because SIRs for most types of cancer were not increased before transplantation, immune suppression may be responsible for the increased risk. (nih.gov)
- The Center of Research in Transplantation and Translational Immunology (CR2TI) gathers researchers and clinicians who develop projects aiming to improve knowledge, diagnosis and treatments in transplantation and immune-mediated inflammatory diseases. (ersnet.org)
Patient's2
- Advantages of living donation for the recipient include shorter waiting times and shorter cold ischemic times for explanted organs, largely because transplantation can be scheduled to optimize the patient's condition. (msdmanuals.com)
- For trainees who are on our services, it's important to show them the impact that we can have on our patients by offering them transplantation, getting them through successful transplantation, and seeing how the patient's quality of life can significantly improve. (medscape.com)
Pancreas1
- Pancreas Transplantation Pancreas transplantation is a form of pancreatic beta-cell replacement that can restore normoglycemia in diabetic patients. (merckmanuals.com)
Milan1
- These criteria plus the absence of extrahepatic and major vessel involvement satisfy the Milan criteria, used to assess suitability of liver transplantation for patients who have cirrhosis and hepatocellular carcinoma. (msdmanuals.com)
Inflammation1
- Inflammation in Parkinson's Disease and Experimental Neural Transplantation. (avhandlingar.se)
Autologous2
- Promising preliminary results are also emanating from an ongoing open randomized clinical study conducted in collaboration with Prof Katarina LeBlanc, KI, Stockholm, in which the efficacy of islet transplantation with or without the support of autologous MSC is investigated. (uu.se)
- The patients will receive autologous MSC, although substantially expanded in vitro prior to transplantation, thereby avoiding potential risk of HLA immunization, transfer of viral infections and other diseases. (uu.se)
Regulatory1
- This is followed by a detailed review of the current progress in the field of regulatory T-cell therapy in transplantation and the translation of this therapy to the clinical setting. (lu.se)
Outcomes1
- All of these conditions lead to poor outcomes during or after transplantation. (msdmanuals.com)
Immunosuppression1
- The new cell therapy was able to reduce the need for immunosuppression in approximately 40 percent of patients, thereby minimizing the risk of side effects," says the study's first author, Prof. Dr. Birgit Sawitzki of the Institute for Medical Immunology on Campus Virchow-Klinikum. (charite.de)
Research1
- His research interests include the role of endothelial cells in graft rejection, complement activation in both kidney and liver transplantation. (medscape.com)
Transplants1
- Annually, more than 500 transplants in the US come from living donors, who can live without their right lobe (in adult-to-adult transplantation) or the lateral segment of their left lobe (in adult-to-child transplantation). (msdmanuals.com)
Post-transplant1
- His current scientific interest focusses on the role of indirect recognition of mismatched HLA in transplantation and on post-transplant immunomonitoring via Next Generation Sequencing of T- and B-cell receptors and immunoglobulins. (umcutrecht.nl)
Bone2
- Is the Subject Area "Bone marrow transplantation" applicable to this article? (plos.org)
- Bone marrow transplantation for leukaemia in Europe. (thieme-connect.de)
Pediatric1
- Dr. Emre is an expert in adult and pediatric liver transplantations. (medscape.com)
Clinically1
- One of the first clinically relevant observations pertaining to transplantation was made by Dr. Earl Padgett in the 1920s, when skin grafts were noted to survive longer when skin from close relatives was used. (medscape.com)
University1
- Dr. Spierings received his PhD degree as immunologist at the Leiden University Medical Center, The Netherlands and was subsequently recognized as SMBWO Immunologist by the Dutch Society for Immunology. (umcutrecht.nl)
Cancer1
- After transplantation, cancer occurred at significantly increased incidence at 25 sites, and risk exceeded 3-fold at 18 of these sites. (nih.gov)