Translocation, GeneticApoptosisCaspasesApoptosis Regulatory ProteinsCaspase 3Proto-Oncogene Proteins c-bcl-2Protein TransportBacterial TranslocationInhibitor of Apoptosis Proteinsbcl-2-Associated X ProteinSignal TransductionDNA FragmentationCell Line, TumorApoptosis Inducing FactorIn Situ Nick-End LabelingCells, CulturedMitochondriaEnzyme ActivationCell SurvivalX-Linked Inhibitor of Apoptosis ProteinCell LineCaspase 9Biological TransportCaspase InhibitorsCASP8 and FADD-Like Apoptosis Regulating ProteinTumor Cells, CulturedCell NucleusCytochromes cTumor Suppressor Protein p53Caspase 8Blotting, WesternProto-Oncogene ProteinsMolecular Sequence DataPhosphorylationFas Ligand ProteinActive Transport, Cell Nucleusbcl-X ProteinTransfectionCell ProliferationEnzyme InhibitorsNF-kappa BChromosomes, Human, Pair 14Annexin A5Membrane ProteinsFlow CytometryCysteine Proteinase InhibitorsCell MembraneCell CycleAmino Acid Chloromethyl KetonesAmino Acid SequenceAntineoplastic AgentsRNA, Small InterferingPoly(ADP-ribose) PolymerasesRNA, MessengerMutationDNA-Binding ProteinsCarrier ProteinsReactive Oxygen SpeciesDown-RegulationDose-Response Relationship, DrugTime FactorsBase SequenceJurkat CellsProtein BindingCell DivisionCytosolTumor Necrosis Factor-alphaGenes, bcl-2Proto-Oncogene Proteins c-aktHL-60 CellsModels, BiologicalCell DeathTranscription FactorsHeLa CellsReverse Transcriptase Polymerase Chain ReactionMembrane Potential, MitochondrialKaryotypingRecombinant Fusion ProteinsProtein-Serine-Threonine KinasesUp-RegulationTNF-Related Apoptosis-Inducing LigandMice, Inbred C57BLIn Situ Hybridization, FluorescenceCytochrome c GroupMembrane GlycoproteinsGene Expression RegulationCaspase 7CytoplasmNeoplasm ProteinsProtein Kinase CIntracellular MembranesDNA DamageChromosomes, Human, Pair 11Gene Expression Regulation, NeoplasticProtein Structure, TertiaryStaurosporineEndoplasmic ReticulumImmunohistochemistryMicroscopy, FluorescenceMice, Knockout