Translational research in brain. Medical search. Frequent questions

This symposium is made possible, in part, with support from the Indiana Clinical and Translational Sciences Institute funded, in part by Grant Number UL1TR002529 from the National Institutes of Health, National Center for Advancing Translational Sciences, Clinical and Translational Sciences Award. (indianactsi.org)
The research described above was supported in part by a UR CTSI Pilot Award through the University of Rochester CTSA award number UL1 TR002001 from the National Center for Advancing Translational Sciences of the National Institutes of Health. (rochester.edu)

The Division of Translational Cancer Research (TCR) was founded 2013 in conjunction with the formation of Lund University Cancer Center (LUCC) at Medicon Village. (lu.se)

Support for clinical research in cardiology. (kbs-frb.be)
Pierluigi Gambetti, MD, has disclosed the following relevant financial relationships: served as an advisor or consultant to and received grants for clinical research from Ferring Pharmaceuticals. (cdc.gov)
These concerns currently hinder the broad dissemination of FC research in translational and pre-clinical research settings. (nature.com)
NINDS supports basic, translational and clinical research within specifically defined areas of neuroscience. (nih.gov)
NIH conducts and supports basic, translational, and clinical research on pain, as well as strategies for treating it. (medlineplus.gov)
Clinical research studies different treatments and interventions to find out whether they are safe and effective in humans. (medlineplus.gov)

The journal's focus is interdisciplinary collaborations between researchers, healthcare providers, and industry and aims to publish results and best practices from these translational efforts. (embs.org)
The purpose of the event is to increase interdisciplinary and translational dialogue and facilitate future collaborations. (uef.fi)
Through the CRCNS program , participating NSF DOs, NIH ICs, BMBF, ANRS and BSF support innovative interdisciplinary collaborative research to make significant advances in the understanding of structures and functions of the nervous system, mechanisms underlying nervous system disorders, and computational strategies used by the nervous system. (nih.gov)
Most of the research in the BME program is highly interdisciplinary, and our students form strong research collaborations with scientists, engineers, and clinicians from Johns Hopkins University and leading academic institutions from around the world. (jhu.edu)
The Translational Research Program (TRP) is the home of the SPOREs-the Specialized Programs of Research Excellence-a cornerstone of NCI's efforts to promote collaborative, interdisciplinary translational cancer research. (unt.edu)
Train and educate graduates of 4-year psychiatry residency training programs in cutting edge interdisciplinary neuropsychiatric research methodologies aimed at advancing precision medicine for the prevention and treatment of mental health disorders and their frequently co-occurring psychiatric, substance abuse and medical complications. (bu.edu)

Inspire talented, innovative and collaborative clinician-scientists to support development of translational biomarkers of pathophysiological processes that contribute to neuropsychiatric disorder risk and chronicity. (bu.edu)

SPIE Brain 2020 will highlight papers from BiOS, LASE and OPTO that describe the development of innovative technologies to increase our understanding of brain function. (techbriefs.com)
SPIE Translational Research 2020 will highlight papers from BiOS that showcase the latest photonics technologies, tools, and techniques with high potential to impact healthcare. (techbriefs.com)
In line with this commitment the Irish Cancer Society has launched the Cancers with Unmet Needs, Translational Research Award 2020. (cancer.ie)
The maximum funding granted for the Cancers with Unmet Needs, Translational Research Award 2020 is €100,000 over 24 months. (cancer.ie)

Preclinical research involving laboratory animals is being conducted to study the principles, mechanisms, and therapeutic effects of deep brain stimulation. (embs.org)
Petersén (PI) and Gabery (co-PI) received a research grant of 1.2 MSEK from the Swedish Brain Foundation (Hjärnfonden) for a project on novel mechanisms of disease and a potential future therapy for HD. (lu.se)
Together, ITN researchers from both groups will use advanced 'big data' analytics to understand the deeper mechanisms of normal brain function and brain disorders. (neuroimpact.ca)
We will not achieve fundamental breakthroughs in curing brain disease unless we understand the basic mechanisms, pathways and circuits that underlie normal brain function and how those mechanisms fail in brain disorders," said Dr. Evans. (neuroimpact.ca)
How computational models can reveal novel brain mechanisms and experimental directions will be interwoven with personal stories. (eurekalert.org)
These symptoms clearly suggest damages and long-term changes caused by SARS-CoV-2 in the brain, the exact molecular mechanisms of which are still poorly understood," Ertürk said. (webmd.com)
Our results indicate that the intrinsic PK/PD relationship in CSF is predictive of that in brain, at least in the postulated pharmacologically relevant range, with excellent consistency across mechanisms and species. (aspetjournals.org)
Basic research in radiobiology, discovery of underlying mechanisms of radiation response, and DNA repair are high priorities for the department of therapeutic radiology at Yale. (yale.edu)
We have to mention that molecular mechanisms underlying the development of embryonal brain tumors of the central nervous system (CNS) are still not well understood. (bvsalud.org)
Our research is strongly embedded in the research of Multipark and contributes to understanding disease mechanisms in neurodegeneration as well as the development of new targets and thereof therapeutic molecules. (lu.se)

Our research is made possible through our dedicated clinic based at the Brain and Mind Centre, Camperdown . (edu.au)

April 13, 2023 - If you or someone you know is experiencing "brain fog" after COVID-19, scientists now have a possible explanation -- and it might not bring much comfort. (webmd.com)

Thursday offers a full day program with various hot topics related to translational neuroscience research, development and innovations, and time for networking and dialogue during the breaks. (uef.fi)
Two of the world's most accomplished neuroscience research initiatives at McGill and Western University have combined their expertise to take on two large-scale brain research projects. (neuroimpact.ca)
Brain and spinal cord tissue is one of the most important resources for neuroscience research. (kcl.ac.uk)

It is the leading academic pediatric neuro-oncology program in the Northwest and includes faculty that lead national pediatric cancer consortiums for clinical trials and new ways to treat brain tumors. (sttrcancer.org)
The Pediatric research program includes the development of molecularly based methods for visualizing tumors during surgery and identifying novel drugs for clinical trials. (sttrcancer.org)
Glioblastoma multiforme (GBM) the highest-grade glioma and deadliest brain tumor occurs in pediatric as well as adult patients. (lu.se)
Cancer genomic studies provided us with a detailed mutational landscape of pediatric brain tumors. (usz.ch)
Given the young age of our patients and potential impact of therapy in the developing central nervous system, we further study the health-related outcomes and long-term impact of therapies in pediatric patients with brain tumors. (usz.ch)
Pediatric high-grade glioma resources from the Children's Brain Tumor Tissue Consortium. (chop.edu)
Dr. Anne Muehe , a postdoctoral fellow in the Pediatric Molecular Imaging Laboratory , received a 2015 RSNA Trainee Research Prize for her research that recently assessed the safety profile of ferumoxytol as an intravenous MRI contrast agent in pediatric patients. (stanford.edu)
In 2010, St. Jude Children's Research Hospital and Washington University School of Medicine launched a $65 million, three-year project to sequence the complete normal and cancer genomes of 600 pediatric cancer patients. (stjude.org)
In the past decade, scientists pinpointed mutations not previously linked to cancer, identified subtype-specific mutations in the brain tumor medulloblastoma, defined novel cancer subtypes, highlighted the developmental context of cancer and revealed the role epigenetics plays in some pediatric cancers. (stjude.org)
The Childhood Solid Tumor Network and PROPEL support preclinical research into pediatric solid tumors and blood cancers such as leukemia. (stjude.org)
The human tumor samples provide the global research community with a free resource to advance understanding and treatment of pediatric cancer. (stjude.org)
The Center for Translational Pediatric Research (CTPR) seeks to investigate how pediatric diseases develop from a systems biology and mechanistic approach, with the ultimate goal of identifying the intersections of disease and development, which will produce targets for therapeutic intervention and the development of new treatments. (archildrens.org)
The long-term goal of the CTPR is to build an innovative, multi-disciplinary pediatric research center that utilizes cutting-edge systems biology technologies and state-of-the-art translational research to study pediatric diseases. (archildrens.org)
Pediatric brain tumors currently show the highest incidence among solid childhood malignancies and, together with leukemia, are the leading cause of death from cancer in childhood. (bvsalud.org)

The brain tissue samples were provided by three Alzheimer's disease centers: Washington University in St. Louis, Mo. (sciencedaily.com)

The Alvord Brain Tumor Center is a collaborative group of physicians and researchers working together to improve the treatment and outcomes of patients with brain tumors. (sttrcancer.org)
Our research programs at the Fred Hutch , Seattle Children's Hospital , and UW Medicine include collaborative patient-based and basic science efforts investigating tumor and stem cell biology, modeling, nanotechnology, drug development and therapeutic response. (sttrcancer.org)
Our collaborative research is demonstrating how genetics, neurobiological factors and parenting styles interact to influence treatment outcomes for children and their families. (edu.au)
While research can take years for patients to see results, these two collaborative neuroscience projects will result in economic and societal impact for Canadians in the next two or three years. (neuroimpact.ca)
The McGill-Western Initiative for Translational Neuroscience (ITN) is a collaborative research initiative supporting two large-scale research projects to impact the lives of those living with neurodegenerative conditions. (neuroimpact.ca)

Our research bridges the gap between basic research and clinical care, to improve the therapies for children and adolescents with brain tumors. (usz.ch)
As part of the neurosciences research program's ongoing commitment to the development of leading-edge medical science, our laboratories are delving into the study of neurodegenerative diseases, brain tumor therapies, Alzheimer's disease, spinal cord injury and stroke, among many others. (cedars-sinai.edu)
Understanding how processes in the brain regulate pain could help researchers develop new pain therapies in the future. (medlineplus.gov)
To identify drugable targets at the vascular/brain interface for the development of novel therapies. (lu.se)
Being a translational group, our vision is to contribute to the discovery and clinical implementation of new therapies for neurological disorders such as Parkinson's disease, Huntington's disease, and stroke. (lu.se)

Many of the NINDS funded bioengineering research focuses on neural interfaces, including neuroprostheses, neuromodulation, brain-computer interface (BCI) devices, prosthetic control, and neural interface technology development. (nih.gov)
Potential applicants are strongly encouraged to discuss their research and application plans with NINDS Program Staff prior to submission. (nih.gov)
NINDS accepts applications for Bioengineering Research Grants (BRG) , and Bioengineering Research Partnerships (BRP) that address technology development and optimization specific to the NINDS mission of basic and translational research to reduce the burden of neurological diseases. (nih.gov)
NINDS seeks fundamental knowledge about the brain and nervous system and to use that knowledge to reduce the burden of neurological disease. (nih.gov)
Research projects considered for funding by NINDS must fall within the scientific research mission of the Institute. (nih.gov)
A key component of research projects submitted to NINDS in response to this FOA is to provide an outstanding opportunity for undergraduates to gain a solid understanding of rigorous scientific methodology within the particular field of study. (nih.gov)
NINDS also strongly urges PIs to engage students from diverse backgrounds and perspectives in their research project. (nih.gov)
It is critical that applicants with research interests relevant to the NINDS mission contact the person listed under Agency Contacts (Section VII) to confirm that the proposed clinical trial meets NINDS' requirements for this funding opportunity. (nih.gov)

KIBRA, and a subset of other molecules directly interacting with it, were significantly altered in regions of the brain involved in Alzheimer's disease pathology. (sciencedaily.com)

NIEHS is committed to conducting the most rigorous research in environmental health sciences, and to communicating the results of this research to the public. (nih.gov)
NIEHS offers a broad range of job opportunities, career enhancement programs, and research training grants and programs in environmental health sciences and administration. (nih.gov)
NCI considers meritorious R15 applications requesting support for cancer research-focused projects across the full spectrum of its mission, including projects focused on studies of cancer biology, etiology, prevention, detection, diagnosis, treatment, control, survivorship, and population sciences. (nih.gov)
Then an M.D./Ph.D. trainee in the UR CTSI's Translational Biomedical Sciences PhD Program, he applied for a pilot research grant to find a target region for diagnosing concussive brain injury and to form a prognosis of what happens to the brain after multiple hits to the head. (rochester.edu)

Local speakers will also be presenting on translational brain tumor research and treatments: Dr. Nuri Damayanti (IU Neurosurgery), Dr. Meenal Datta (University of Notre Dame Engineering), Dr. Sandro Matosevic (Purdue University Pharmacy), Dr. Jignesh Tailor (IU Neurosurgery), Dr. Michael Veronesi (IU Neuroradiology), and Dr. Charles Yates (IU Neurotology). (indianactsi.org)
A link has been announced between the brain protein KIBRA and Alzheimer's disease, a discovery that could lead to promising new treatments for this memory-robbing disorder. (sciencedaily.com)
The hope is researchers can develop treatments that block one or more steps in this process and help people avoid long COVID brain issues. (webmd.com)
By comparing changes in the brain with progression of memory impairment we support the development of more effective treatments. (kcl.ac.uk)
Our scientists pursue every aspect of cancer research-from exploring the biology of genes and cells, to developing immune-based treatments, uncovering the causes of metastasis, and more. (mskcc.org)
Using these new findings, Huang and Brain Cancer TRI collaborators will work to develop new treatments that slow or stop tumour stiffening and restore normal physical characteristics of the brain. (oicr.on.ca)
This research is a step toward identifying new and effective pain relief treatments. (medlineplus.gov)

Clinicians and researchers interested in improving the care of brain tumor patients are invited to attend. (indianactsi.org)
In addition to helping those with brain disorders, these projects will use open science tools, which will make the data accessible to a global community of researchers and clinicians. (neuroimpact.ca)
While each project has a specific focus, the findings in any of these areas will help researchers better understand the intricacies of the brain, something that Dr. Evans explained leads to advances that will benefit those suffering from a brain condition. (neuroimpact.ca)
By making research easy to access, and puts the academic needs of the researchers before the business interests of publishers. (intechopen.com)
Researchers in Germany found that part of the virus, the spike protein, remains in the brain long after the virus clears out. (webmd.com)
Researchers also found no SARS-CoV-2 virus in the brain parenchyma, the functional tissue in the brain containing nerve cells and non-nerve (called glial) cells, but they did detect the spike protein there. (webmd.com)
While pursuing their research activities, students attend programs led by preeminent cancer researchers and innovators in cancer care. (mskcc.org)
Researchers explained that following a stroke, the makeup of a patient's blood changes, causing disruptions in the brain and how the body responds. (news-medical.net)
Educational activities will include monthly in-person research presentations by Fellows, faculty members, and outside researchers. (bu.edu)
Researchers at the National Institute of Dental and Craniofacial Research (NIDCR) hoped to explore new ways to treat facial pain without unwanted side effects. (medlineplus.gov)

To search the bioengineering projects funded at NIH please go to NIH RePORTER , or select bioengineering research in the categorical spending . (nih.gov)

Reported neurological problems include brain fog, brain tissue loss, a decline in thinking abilities, and problems with memory, he said. (webmd.com)
Designing treatment strategies for these neurological symptoms requires an in-depth knowledge of molecules dysregulated by the virus in the brain tissues," Ertürk said. (webmd.com)
This blood swap lessens damage to your brain, and any neurological deficits from the stroke are nil. (news-medical.net)

His research goal is to address the molecular basis of brain tumors and develop new treatment approaches. (sttrcancer.org)
A Feature Paper should be a substantial original Article that involves several techniques or approaches, provides an outlook for future research directions and describes possible research applications. (mdpi.com)
Apply innovative experimental and data-driven approaches to understand, diagnose, and treat disorders of the brain. (jhu.edu)

Together, our results demonstrate that the FMP Y-maze is a sensitive assay for assessing working memory and cognitive flexibility across species from invertebrates to humans, providing a simple and widely applicable behavioural assay with exceptional translational relevance. (springer.com)

For more information visit the BRAIN Initiative website. (nih.gov)
Established as part of the newly developed McGill-Western Initiative for Translational Neuroscience (ITN), these projects are supported by the Canada First Research Excellence Fund (CFREF) through Western's BrainsCAN and McGill's Healthy Brains, Healthy Lives (HBHL) initiatives. (neuroimpact.ca)
Preliminary exploratory data analysis of simulated national clinical data research network for future use in annotation of a rare tumor biobanking initiative. (chop.edu)
Open Access is an initiative that aims to make scientific research freely available to all. (intechopen.com)
King's Brain Bank is also part of the Brains for Dementia Research initiative, in which brain tissue from regularly assessed individuals provides the best resource for scientists working to understand dementia. (kcl.ac.uk)
The research is funded in part through OICR's Brain Cancer Translational Research Initiative (TRI). (oicr.on.ca)

It is a potential breakthrough in stroke therapy based on mice research by West Virginia University neuroscientists. (news-medical.net)
The study's co-authors include Heng Hu, postdoctoral fellow and Experimental Stroke Core surgeon, and James Simpkins, director of the Center for Basic & Translational Stroke Research and professor of the Department of Neuroscience. (news-medical.net)
Blood indeed saves our brains and lives from stroke damage,' she said. (news-medical.net)
The lack of oxygen and glucose in the area of ischemic injury initiates a pathological cascade leading to blood-brain barrier (BBB) breakdown, inflammation, and neuronal cell death, a process that may be intercepted to limit stroke progression. (lu.se)
Pericytes located at the blood/brain interface are one of the first responders to hypoxia in stroke and therefore a potential target cell for early stroke interventions. (lu.se)

Brain tumors are the most common cause of cancer-related death and morbidity in infants, children and adolescents. (usz.ch)
Embryonal brain tumors are the most common and frequent type of childhood brain cancer and are usually characterized by an extremely aggressive course of the disease with the worst outcomes in most cases. (bvsalud.org)

Secondary, or metastatic, brain tumors are about four times as common as primary brain tumors, with about half of metastases coming from lung cancer. (wikipedia.org)
Globally and nationally survival has not dramatically increased in some cancer groups such as rare cancers, cancers affecting children and young adults, as well as hard-to-treat cancers like primary and metastatic forms of lung, pancreatic and oesophageal cancers and brain tumours. (cancer.ie)

Visit the Brain Tumor Biology groups research portal via this link. (lu.se)
NIEHS research uses state-of-the-art science and technology to investigate the interplay between environmental exposures, human biology, genetics, and common diseases to help prevent disease and improve human health. (nih.gov)
Research in Radiobiology is centered on the molecular biology of living cells. (yale.edu)
We discovered the mechanism that senses and amplifies tumour stiffness in brain cancer," says Dr. Xi Huang, Scientist in the Developmental and Stem Cell Biology program at SickKids, Assistant Professor in the Department of Molecular Genetics at the University of Toronto, and lead of this study. (oicr.on.ca)
This is exactly what the brain tumour field needs," says Dr. Peter Dirks, Co-Leader of OICR's Brain Cancer TRI, Staff Neurosurgeon and Senior Scientist in the Developmental and Stem Cell Biology program at SickKids and a co-author of this publication, "This discovery opens doors to completely new ways of thinking about how to treat these aggressive tumours. (oicr.on.ca)

In this study, we strived to elucidate how the intrinsic pharmacokinetic (PK)/pharmacodynamic (PD) relationship for CSF Aβ lowering is related to that for brain Aβ through quantitative modeling of preclinical data for numerous BACEi, GSI, and GSM across multiple species. (aspetjournals.org)
We further discuss the implications of our findings to drug discovery and development with regard to preclinical PK/PD characterization and clinical prediction of Aβ lowering in the brain. (aspetjournals.org)
As a translational neurologist, Gesine Paul is also working on the implementation of novel preclinical findings by performing phase 1 clinical trials (e.g. growth factors, fetal cells, dopaminergic stem cells) in individuals with Parkinson's disease. (lu.se)
Moreover, it is ideally suited for translational research, bridging the gap between the preclinical and standard clinical MR technologies. (lu.se)

The Alvord Brain Tumor Center (ABTC) was established to unite research and clinical faculty across the Fred Hutch/University of Washington Cancer Consortium in work related to brain cancer. (sttrcancer.org)

Support to scientific research into neurodegenerative diseases of the brain such Parkinson's disease and Alzheimer's disease. (kbs-frb.be)
Prof. Dr Ludo Van Den Bosch is awarded the Generet Prize for Rare Diseases (€ 1,000,000) for his research into motor neuron disease ALS. (kbs-frb.be)
One project is developing a better method to test and evaluate drugs for brain diseases and disorders, while the other is identifying a faster and more efficient method to diagnose Parkinson's. (neuroimpact.ca)
Our extensive range of highly-preserved tissue samples provide invaluable insights for our scientists working to improve the diagnosis and treatment of the most severe diseases and disorders affecting the brain. (kcl.ac.uk)
London Neurodegenerative Diseases Brain Bank provides a variety of tissue to further research projects among the neuroscience community worldwide. (kcl.ac.uk)
Translational research takes information learned from basic research and studies how it can help improve health and treat diseases. (medlineplus.gov)

Deep brain stimulation has emerged as an effective medical procedure that has therapeutic efficacy in a number of neuropsychiatric disorders. (embs.org)
The Translational Devices program provides support for the development, optimization, translation, and first-in-human testing of therapeutic and diagnostic devices for disorders that affect the nervous or neuromuscular systems. (nih.gov)
The Next-Generation Invasive Devices for Recording and Modulation in the Human Central Nervous System program encourages applicants to pursue milestone-driven translational and clinical projects for implantable recording and/or stimulating devices to treat central nervous system (CNS) disorders and better understand the human brain. (nih.gov)
Brain disorders are increasing rapidly, especially as Canada's population ages, so it's critical that we move brain research from the lab to the real world as quickly as we can," said Dr. Saksida. (neuroimpact.ca)
Zebrafish offer a promising model for studying complex brain disorders, but tasks assessing executive function are lacking. (springer.com)

A bottleneck is, however, the lack of deep brain stimulation devices that enable long term brain stimulation in freely moving laboratory animals. (embs.org)
In long term behavioral trials, however, laboratory animals often need to continuously receive brain stimulation for days without interruption, which is difficult with existing technology. (embs.org)
This paper presents a low power and lightweight portable microdeep brain stimulation device for laboratory animals. (embs.org)

This research suggests that KIBRA, and possibly some of the proteins with which it interacts, may play a role in Alzheimer's disease,'' said Dr. Matthew Huentelman, an investigator in TGen's Neurogenomics Division and the paper's senior author. (sciencedaily.com)
The critical difference found in KIBRA, a protein so named because it is commonly found in the kidneys and brain, was that those individuals with the T-allele gene were less likely to develop Alzheimer's than those with the C-allele. (sciencedaily.com)
We believe this variation causes a potential lifelong difference in the total levels of KIBRA in the brain, and that this may influence one's risk for Alzheimer's," said Huentelman, who led a team that worked with several Arizona institutions, as well as other national and international universities and research institutions. (sciencedaily.com)
Using a brain imaging technique called positron emission tomography (PET) to find that cognitively-normal, late-middle-aged people lacking the protective T-allele gene had reduced activity in parts of the brain usually affected by Alzheimer's. (sciencedaily.com)
Your help could improve Alzheimer's Disease research, motor neuron disease, Huntington's Disease. (kcl.ac.uk)
Reducing the generation of amyloid-β (Aβ) in the brain via inhibition of β-secretase or inhibition/modulation of γ-secretase has been pursued as a potential disease-modifying treatment for Alzheimer's disease. (aspetjournals.org)

The inaugural IU Brain Tumor Translational Research Day will be held on Saturday, December 3 from 8 am - 3 pm, at the Goodman Hall Auditorium at Stark Neurosciences Research Institute, 320 W 15th Street, Indianapolis, IN 46202. (indianactsi.org)
and Sun Health Research Institute in Sun City, Ariz. (sciencedaily.com)
If you are giving a presentation about an environmental health topic or just looking for general information about environmental health research or the institute, this page will help. (nih.gov)
In this lecture, Hee-Sup Shin, MD, PhD, of the Institute for Basic Science in Daejeon, Korea, will overview the current research on the neurobiology of empathy. (eurekalert.org)
A. James Hudspeth, MD, PhD, of the Howard Hughes Medical Institute and Rockefeller University, will describe the fascinating research behind the gateway to human connection: the sense of hearing. (eurekalert.org)
This is a very concerning report that literally demonstrates the SARS-CoV-2 spike protein in the skull-meninges-brain axis in postmortem individuals," said Eric Topol, MD, director of the Scripps Research Translational Institute in La Jolla, CA, and editor-in-chief of Medscape, WebMD's sister site for medical professionals. (webmd.com)
The Robarts Research Institute has awarded the 2015 J. Allyn Taylor International Prize in Medicine to Sanjiv S. Gambhir, MD, PhD . (stanford.edu)
The Taylor Prize is awarded annually by Western University's Robarts Research Institute. (stanford.edu)
The Brain Bank is partially funded by the Medical Research Council (MRC) and is part of the Basic and Clinical Neuroscience department at the Institute of Psychiatry, Psychology and Neuroscience (IoPPN) and the Department of Clinical Neuropathology at King's College Hospital. (kcl.ac.uk)
Receive the latest news, event invites, funding opportunities and more from the Ontario Institute for Cancer Research. (oicr.on.ca)

The department has a large number of competitive research grants from the NIH and other funding agencies. (yale.edu)

Medical students, who are between the first and second years of school, work on research projects under the mentorship of MSK faculty members. (mskcc.org)

The UR CTSI Pilot Studies Program provides seed funding for highly innovative research that spans the translational spectrum. (rochester.edu)

He has vast experience in conducting clinical trials in glioma patients and developing imaging strategies to follow mouse brain tumors as they develop. (sttrcancer.org)
More specifically, support to research projects that explore and develop an innovative, non-pharmacological approach to the functional, clinical and/or psychosocial problems facing older people with a neurodegenerative brain disease and, that contribute towards a better treatment and care. (kbs-frb.be)
The Virtual Consortium for Translational/Transdisciplinary Environmental Research (ViCTER) program brings together diverse research teams that may include scientists who develop technologies, conduct basic mechanistic or population-based studies, and those that are clinical and patient-oriented. (nih.gov)
Even people who had mild COVID illness can develop brain fog later, Ertürk and colleagues note. (webmd.com)
Uncontrolled cell growth in solid tumours, such as brain tumours, causes tumour tissue to be stiffer than healthy tissue, creating an advantageous environment for tumour cells to proliferate rapidly, avoid cell death and develop resistance to drugs. (oicr.on.ca)

Neutrophils, a type of white blood cell that helps lead the immune system's response, play a role in increasing the levels of an enzyme called MMP-9, which can lead to blood-brain barrier leakage and degeneration in brain tissue. (news-medical.net)
Animal studies suggest that disruption of the blood-brain barrier is likely to contribute to the generation of seizures in PTE. (medscape.com)
In my group, we examine how microvascular alterations at the blood-brain barrier contribute to the pathogenesis of neurodegeneration. (lu.se)

These investigators discovered the spike protein from the virus in brain tissue of animals and people after death. (webmd.com)
The Brain Bank was established in 1989 with the aim of providing high quality, clinically and neuropathologically well-characterised human brain and spinal cord tissue to the neuroscience community. (kcl.ac.uk)
From surgical tissue, fixed tissue to frozen tissue and cerebrospinal fluid (CSF), the brain bank is the number one source to many medical and commercial companies around the world. (kcl.ac.uk)
Highly trusted by the research community and beyond, the brain bank assures quality standards of tissue provision. (kcl.ac.uk)
A reduction in cerebral blood flow in brain tissue is typically accompanied by a compensatory increase in the oxygen extraction fraction (OEF) to maintain normal neuronal function. (ajnr.org)
The mechanism by which trauma to brain tissue leads to recurrent seizures is unknown because there are so many different types of head insults and the excitatory cascade is a series of complex processes. (medscape.com)
Brain tumour tissue is often stiffer than normal tissue. (oicr.on.ca)
A research group based at the The Hospital for Sick Children (SickKids) recently discovered how tumour cells sense and respond to tissue rigidity. (oicr.on.ca)
The research team found that a specific cell-surface ion channel, PIEZO1, regulates cell proliferation and tissue stiffening in glioma - the most common type of brain cancer. (oicr.on.ca)

The Society for Neuroscience (SfN) is an organization of nearly 35,000 basic scientists and clinicians who study the brain and the nervous system. (eurekalert.org)
Dr. Stroud has both veterinary and basic research backgrounds holding both a DVM and a PhD in basic endocrine physiology with professional experiences in industry, academic research and training, private veterinary practice, and One Health leadership. (cdc.gov)
For this FOA, projects are limited to prospective basic science studies involving human participants that fall within the broad NIH definition of a clinical trial and also meet the definition of basic research as described in NOT-OD-18-212 . (nih.gov)
Basic research is conducted in labs by scientists who study the most fundamental building blocks of life, including genes, proteins, and cells. (medlineplus.gov)

Tumor cells with stem cell characteristics are thought to be responsible for therapeutic resistance in brain tumors. (lu.se)
Using mouse models of glioma and primary human glioma cultures, we aim to characterize phenotypic intratumoral heterogeneity specifically with regards to radiation resistant stem-like tumor cells, the molecular signaling pathways underlying therapeutic resistance, and microenvironmental control over tumor cell phenotypes with the overall goal of developing novel therapeutic strategies targeting therapy-resistant cells in malignant brain tumors. (lu.se)

The cause of most brain tumors is unknown, though up to 4% of brain cancers may be caused by CT scan radiation. (wikipedia.org)
Primary brain tumors occur in around 250,000 people a year globally, and make up less than 2% of cancers. (wikipedia.org)
The program is open to additional organ system translational research, including research in less common cancers. (unt.edu)
These cancers continue to have unmet needs in terms of lack of effective treatment options and/or lack of research capacity within the area, both of which contributes to inferior survival and outcome. (cancer.ie)

Submenu for How does research happen? (lu.se)

A new paper on imaging brain tumors from the Gambhir Lab was published in Science Translational Medicine and is also the cover article. (stanford.edu)
In addition, more than 35 research papers have appeared in peer-reviewed journals, including some of the most prestigious, such as the New England Journal of Medicine , Nature and Nature Genetics . (stjude.org)

The ABTC bridges multi-disciplinary experts with the goal of speeding new developments in cancer prevention, diagnosis and treatment utilizing novel findings like precision oncology tools to lengthen survival and create cures for brain cancer patients. (sttrcancer.org)

The study proposes that if the function of PIEZO1 in brain tumours could be controlled, then in turn, tumour stiffening and aggression could be controlled. (oicr.on.ca)

Prof Safa Al-Sarraj - Director of Brain Bank and Head of Clinical Neuropathology department. (kcl.ac.uk)

Dr. Milan G. Chheda, associate professor at Washington University in St. Louis with research interests in cancer stem cells, oncolytic viruses, and functional genomics of brain tumors, will be giving a keynote address. (indianactsi.org)

Dr Eric Holland explains obstacles brain cancer researcher face. (sttrcancer.org)
Dr. Holland is a neurosurgeon and brain cancer researcher. (sttrcancer.org)
His research focuses on developing mouse models of brain cancer that mimic how the disease behaves in patients. (sttrcancer.org)
In children younger than 15, brain tumors are second only to acute lymphoblastic leukemia as the most common form of cancer. (wikipedia.org)
In NSW Australia in 2005, the average lifetime economic cost of a case of brain cancer was AU$1.9 million, the greatest of any type of cancer. (wikipedia.org)
Headaches as a result of raised intracranial pressure can be an early symptom of brain cancer. (wikipedia.org)
Certain warning signs for headache exist which make the headache more likely to be associated with brain cancer. (wikipedia.org)
A key priority for the Irish Cancer Society isto ensure that all patients in our community benefit from world class cancer research and expertise, and that the gap in survival between different cancer groups is closed. (cancer.ie)
The aim of the award is to provide funding for a translational research project that addresses an issue(s) in a cancer with an unmet need - a cancer that has a lack of effective treatment options and/or a lack of research capacity in the area. (cancer.ie)
Our highly-specialized educational programs shape leaders to be at the forefront of cancer care and research. (mskcc.org)
In addition, there is research on the role of oncogenes in cancer, RNA processing in eukaryotes and radiobiology topics related to cancer therapy. (yale.edu)
TCR consists of nine research groups with different areas of expertise, but together working on projects with the common goal of improving cancer diagnostics and cancer therapy. (lu.se)
Breast Cancer Research. (lu.se)

Damage to Myelin and Oligodendrocytes: A Role in Chronic Outcomes Following Traumatic Brain Injury? (mdpi.com)
[ 1 ] This injury may be due to multiple types of head insults often labled traumatic brain injury (TBI). (medscape.com)

As part of the €100,000 funding, a mandatory provision of €1,000 is available to support Public and Patient Involvement (PPI) in the proposed research project. (cancer.ie)
Enable timely acquisition of career-awards or other early stage funding to support promising clinician-scientists in development of research and clinical careers in precision neuropsychiatry. (bu.edu)
Biostatistics support needed for development of research presentations and grant development also will be provided. (bu.edu)

They also injected the spike protein directly into the brains of mice and showed it can cause cells to die. (webmd.com)
In the study, led by Xuefang 'Sophie' Ren, research assistant professor in the Department of Neuroscience, the team found that blood substitution therapy rescues the brains of mice from ischemic damage. (news-medical.net)

Each consortium sets research goals in an area where environmental factors are known or expected to influence the development or progression of disease. (nih.gov)
For the discovery and development of β-secretase inhibitors (BACEi), γ-secretase inhibitors (GSI), and γ-secretase modulators (GSM), Aβ in cerebrospinal fluid (CSF) has been presumed to be an effect biomarker for Aβ lowering in the brain. (aspetjournals.org)
This study was supported by Pfizer Worldwide Research and Development, Pfizer Inc. (aspetjournals.org)
Therefore, the development of the corresponding translational rodent models is also of great interest. (nature.com)
New research funded by OICR helps to explain how this occurs - and how this knowledge can be used to help slow tumour development. (oicr.on.ca)

NIEHS intramural scientists have defined descriptive terms of particular relevance to their own research, and have ranked those terms accordingly. (nih.gov)
Partnerships among scientists who might not normally work together can quicken the pace at which research moves forward. (nih.gov)
By participating in this broadly based program of cooperation between agencies, the NIH will focus on creating new research teams of biomedical and quantitative scientists to explore questions directly relevant to the missions of participating NIH ICs. (nih.gov)
As PhD students, we found it difficult to access the research we needed, so we decided to create a new Open Access publisher that levels the playing field for scientists across the world. (intechopen.com)

The facility can offer equipment for brain, knee, wrist, breast and abdominal imaging, fMRI stimuli and eye tracking as well as clinical devices, such as contrast injector and ventilator. (lu.se)

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