AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesDisciplines and OccupationsInformation ScienceHealth Care
Ischemic Attack, TransientCalciumTime FactorsTransient Receptor Potential ChannelsCalcium SignalingAmnesia, Transient GlobalCells, CulturedMolecular Sequence DataTRPC Cation ChannelsKineticsMembrane PotentialsTransfectionCell LineAction PotentialsBase SequenceRats, Sprague-DawleyPromoter Regions, GeneticPatch-Clamp TechniquesCalcium ChannelsNeuronsRNA, MessengerCaffeineTRPM Cation ChannelsSignal TransductionElectrophysiologyTranscription, GeneticRats, WistarGene Expression RegulationFura-2Dose-Response Relationship, DrugAequorinSarcoplasmic ReticulumMyocardial ContractionPotassiumBrain IschemiaMyocardiumTranscription FactorsModels, BiologicalElectric StimulationFluorescent DyesAmino Acid SequenceDNA-Binding ProteinsMice, Inbred C57BLMyocytes, CardiacMutationGene ExpressionRabbitsProtein BindingEgtazic AcidCapsaicinPhosphorylationEnzyme InhibitorsHeart VentriclesBrainCytosolHeartPotassium ChannelsCalcium Channel BlockersSodium-Calcium ExchangerStrokeThapsigarginDisease Models, AnimalSodiumElectric ConductivityHippocampusBinding SitesRyanodineRecombinant ProteinsAdenosine TriphosphateMuscle ContractionCalcium Channels, L-TypeEnzyme Activation4-AminopyridineMicroscopy, ConfocalRecombinant Fusion ProteinsAnimals, NewbornBlotting, WesternCell MembraneShal Potassium ChannelsTumor Cells, CulturedDNAXanthenesGuinea PigsIon ChannelsDogsPlasmidsGenes, ReporterCloning, MolecularInfarction, Middle Cerebral ArteryMicroscopy, FluorescenceIntracellular FluidReperfusionGerbillinaeHydrogen-Ion ConcentrationChloramphenicol O-AcetyltransferaseIon TransportGreen Fluorescent ProteinsTranscriptional ActivationMice, KnockoutImmunohistochemistry
EmbolismTachypnea of the newbornHypertensionArtery smooth musclIschemic attacksEdemaVenousStenosisIdiopathicEarly wheezeReceptor potential channelFibrosisCOPDChronic pulmonaryArterial pressureCongenitalPersistentLung functionMyocardialAlveolarHypothyroidismAcuteArteriesAirwayTRPV4EchocardiographyVentilationClinicallyRadiographicExacerbationsClinicalRespiratory distressPatientsAsthmaFunctionAdultDiseaseRecipientsAssessPediatricSyndromeFindings
Embolism9
  • COVID-19 Vaccine and Pulmonary Embolism: Is There a Link? (healthline.com)
  • Can the COVID-19 Vaccine Cause Pulmonary Embolism? (healthline.com)
  • A pulmonary embolism (PE) is a blood clot that breaks off from a deep vein and travels to a lung artery, where it blocks blood flow. (healthline.com)
  • While very rare, this vaccine side effect can cause a pulmonary embolism. (healthline.com)
  • What's the link between the COVID vaccines and pulmonary embolism? (healthline.com)
  • Doctors also refer to pulmonary embolism and deep vein thrombosis as venous thromboembolism (VTE) . (healthline.com)
  • Who's most at risk of pulmonary embolism from the COVID vaccine? (healthline.com)
  • Is the COVID vaccine safe for people at risk of pulmonary embolism? (healthline.com)
  • If you're at risk for a pulmonary embolism, you should strongly consider getting an mRNA vaccine, such as Moderna or Pfizer . (healthline.com)
Tachypnea of the newborn1
  • Transient tachypnea of the newborn (TTN) represents persistence of fetal lung fluid at birth and generally presents within a few hours of birth. (medscape.com)
Hypertension8
  • [ 1 , 2 ] Malignant TTN has been reported in some cases, where newborns develop persistent pulmonary hypertension from the possible increase in pulmonary vascular resistance as a result of retained lung fluid. (medscape.com)
  • 4-8] Some patients develop recurrent respiratory infections, dyspnea, exercise intolerance, hemoptysis and pulmonary hypertension in the contralateral pulmonary artery. (narayanahealth.org)
  • Classical transient receptor potential channel 1 in hypoxia-induced pulmonary hypertension. (nih.gov)
  • While the maintenance of ventilation/perfusion ratio during regional obstruction of airflow is beneficial, HPV can be detrimental during global alveolar hypoxia which occurs with exposure to high altitude, where HPV causes a significant increase in total pulmonary vascular resistance, and pulmonary arterial pressure, potentially leading to pulmonary hypertension and pulmonary edema. (wikipedia.org)
  • Persistent pulmonary hypertension of the newborn (PPHN) is defined as the failure of the normal circulatory transition that occurs after birth. (medscape.com)
  • It is a syndrome characterized by marked pulmonary hypertension that causes hypoxemia secondary to right-to-left shunting of blood at the foramen ovale and ductus arteriosus. (medscape.com)
  • Idiopathic persistent pulmonary hypertension of the newborn can present without signs of acute perinatal distress. (medscape.com)
  • In contrast to adult primary pulmonary hypertension, the newborn syndrome is not defined by a specific pressure of the pulmonary circulation. (medscape.com)
Artery smooth muscl1
  • The classical explanation of HPV involves inhibition of hypoxia-sensitive voltage-gated potassium channels in pulmonary artery smooth muscle cells leading to depolarization. (wikipedia.org)
Ischemic attacks1
  • or temporary stroke-like episodes known as transient ischemic attacks. (medlineplus.gov)
Edema4
  • [ 5 ] TTN radiographic lung changes also may resemble the interstitial pattern of other causes of pulmonary edema, and echocardiography may be useful if there is an atypical course or abnormal cardiac size (cardiomegaly) and/or contour is suspected. (medscape.com)
  • This hypoxia causes vasoconstriction that ultimately leads to high altitude pulmonary edema (HAPE). (wikipedia.org)
  • Cats from 4 referral centres presenting for CHF (pulmonary edema and pleural effusion) were included. (vin.com)
  • These may include myocarditis or myocardial edema (due to infections such as toxoplasma or FIV, neoplastic infiltration, or other processes), or transient cardiomyopathies such as the stress-induced "Takotsubo cardiomyopathy" seen in humans or the "capture myopathy" seen in confined wildlife. (vin.com)
Venous1
Stenosis1
  • coarctation of the aorta (either isolated or in combination with a ventricular septal defect), subvalvular aortic stenosis , transposition of the great arteries (either isolated or in combination with ventricular septal defect or pulmonary stenosis), Taussig-Bing malformation and coarctation, congenitally corrected transposition and pulmonary stenosis, and Scimitar syndrome. (narayanahealth.org)
Idiopathic4
  • Idiopathic pulmonary fibrosis in children is rare and poorly understood. (bmj.com)
  • We report our experience over the past 12 years treating 11 infants with the diagnosis of idiopathic pulmonary fibrosis, all of whom have survived to a median age of 6 years (range 1 to 12 years). (bmj.com)
  • Idiopathic pulmonary fibrosis (or cryptogenic fibrosing alveolitis) (IPF or CFA) is one of several idiopathic interstitial pneumonias. (atsjournals.org)
  • The purpose of this consensus statement is to provide assistance to clinicians in the diagnosis and management of idiopathic pulmonary fibrosis (IPF). (atsjournals.org)
Early wheeze1
  • Objective: We investigated whether replicated genes for COPD associate with transient early wheeze (TEW) and lung function levels in 6-to 8-year-old children and whether cigarette smoke exposure in utero and after birth (environmental tobacco smoke [ETS]) modifies these effects. (maastrichtuniversity.nl)
Receptor potential channel1
  • The Role of Transient Receptor Potential Channel 6 Channels in the Pulmonary Vasculature. (nih.gov)
Fibrosis5
  • Transient expression of IL-1beta induces acute lung injury and chronic repair leading to pulmonary fibrosis. (ox.ac.uk)
  • BACKGROUND Pulmonary interstitial fibrosis in children is a disease of unknown aetiology, usually associated with a poor prognosis. (bmj.com)
  • Pulmonary interstitial fibrosis in children is a heterogeneous group of progressive lung disorders characterised by a pattern of inflammation and subsequent interstitial fibrosis that predominantly affects the alveolar walls and perialveolar structures. (bmj.com)
  • Most cases of pulmonary fibrosis have no associated aetiology and are classified by histological features which include usual interstitial pneumonitis (UIP), desquamative interstitial pneumonitis (DIP), lymphocytic interstitial pneumonitis (LIP), and bronchiolitis obliterans with organising pneumonia (BOOP). (bmj.com)
  • Many acute and chronic lung disorders with variable degrees of pulmonary inflammation and fibrosis are collectively referred to as interstitial lung diseases (ILDs) or diffuse parenchymal lung diseases. (atsjournals.org)
COPD5
  • Background: It has been hypothesized that a disturbed early lung development underlies the susceptibility to chronic obstructive pulmonary disease (COPD). (maastrichtuniversity.nl)
  • Advair Diskus and Advair HFA (fluticasone propionate and salmeterol oral inhaler) is a combination of a corticosteroid and a beta2-adrenergic bronchodilator used to treat asthma or chronic obstructive pulmonary disease ( COPD ) associated with chronic bronchitis . (medicinenet.com)
  • Chronic pulmonary aspergillosis affects patients without obvious immune compromise, but with an underlying lung condition such as COPD or sarcoidosis, prior or concurrent TB or non-tuberculous mycobacterial disease. (bmj.com)
  • In patients with known chronic obstructive pulmonary disease (COPD), exacerbations occur an average of 1.3 times per year. (aafp.org)
  • The course of chronic obstructive pulmonary disease (COPD) is characterized by acute exacerbations, commonly requiring hospital admission and often associated with the development of respiratory failure. (atsjournals.org)
Chronic pulmonary2
  • Cases of extrinsic allergic alveolitis and chronic pulmonary aspergillosis have been observed after Aspergillus exposure. (bmj.com)
  • Chronic pulmonary aspergillosis (CPA) presents in a more indolent fashion, usually affecting patients with underlying lung disease, but with no or only subtle generalised immune compromise. (bmj.com)
Arterial pressure1
  • The diagnosis is confirmed regardless of the pulmonary arterial pressure, as long as it is accompanied by a right-to-left shunt and absence of congenital heart disease. (medscape.com)
Congenital3
  • Unilateral absence of pulmonary artery (UAPA) is a rare congenital anomaly that can present as an isolated lesion or may be associated with other Congenital heart diseases . (narayanahealth.org)
  • Congenital "unilateral absence of a pulmonary artery" is a rare malformation. (narayanahealth.org)
  • In contrast, 75% of patients with "absent" left pulmonary artery have associated congenital cardiac anomalies. (narayanahealth.org)
Persistent1
  • Although transient early wheezers were found to have normal-to-subnormal lung function, children with asthmatic symptoms (persistent and late-onset disease) at age 7 yrs already show significant impairment of expiratory flow volumes. (ersjournals.com)
Lung function4
  • In the group of transient early wheezers, frequent lower respiratory tract infections early in life and maternal smoking during pregnancy were significant but weak determinants of impaired lung function. (ersjournals.com)
  • Conclusions Abnormalities in pulmonary vascular volumes may explain some of the lung function abnormalities and the decline in lung function seen in adults with SCD. (bmj.com)
  • Alterations in pulmonary vascular volumes due to anaemia in SCD patients may be responsible for some of their lung function abnormalities and changes seen on HRCT and their decline in lung function. (bmj.com)
  • The study on twelve male patients with obstructive pulmonary disease showed transient improvement in general lung function. (fleetfeet.com)
Myocardial4
  • 21 cats were identified with Transient Myocardial Thickening (TMT). (vin.com)
  • The authors suggest several possible etiologies for this transient myocardial thickening. (vin.com)
  • Transient ischemic dilation (TID) in the setting of abnormal stress-rest cardiac SPECT myocardial perfusion imaging (MPI) has been linked with increased cardiovascular risk. (snmjournals.org)
  • Transient ischemic dilation (TID) on stress SPECT myocardial perfusion imaging (MPI) is defined as the apparent presence of left ventricular (LV) dilation on poststress relative to rest images. (snmjournals.org)
Alveolar2
  • Hypoxic pulmonary vasoconstriction (HPV), also known as the Euler-Liljestrand mechanism, is a physiological phenomenon in which small pulmonary arteries constrict in the presence of alveolar hypoxia (low oxygen levels). (wikipedia.org)
  • Recently it was proposed that hypoxia is sensed at the alveolar/capillary level, generating an electrical signal that is transduced to pulmonary arterioles through gap junctions in the pulmonary endothelium to cause HPV. (wikipedia.org)
Hypothyroidism2
  • Transient Hypothyroidism in a new born is either due to transplacentally acquired TSH binding inhibitory immunoglobulins, maternal exposure to goitrogens (iodides or anti- thyroid drugs), transient hypothyroxinemia of Prematurity or sick euthyroid syndrome. (narayanahealth.org)
  • 4,10-13] We report for the first time from India the case of a new born baby with Absent Right Pulmonary Artery and Bronchiectasis of Right Lower Lobe with Transient Hypothyroidism. (narayanahealth.org)
Acute3
  • Mitochondrial Complex IV Subunit 4 Isoform 2 Is Essential for Acute Pulmonary Oxygen Sensing. (nih.gov)
  • Acute chest syndrome is the commonest cause of death in young adults, and pulmonary dysfunction is a major contributor to morbidity in aging adults with SCD. (bmj.com)
  • The detailed mechanisms of oxygen-induced hypercapnia were examined in 22 patients during an acute exacerbation of chronic obstructive pulmonary disease. (atsjournals.org)
Arteries1
  • It often affects the brain or stomach, but it can also affect the pulmonary arteries. (healthline.com)
Airway1
  • Terbutaline sulfate also produces a clinically significant decrease in airway and pulmonary resistance, which persists for 4 hours or longer. (nih.gov)
TRPV42
  • The mechanism of activation of the transient receptor potential vanilloid 4 (TRPV4) channel by 4α-phorbol esters was investigated by combining information from chemical modification of 4α-phorbol-didecanoate (4α-PDD, 2a ), site-directed mutagenesis, Ca 2+ imaging, and electrophysiology. (acs.org)
  • However, later studies have reported additional ion channels and mechanisms that contribute to HPV, such as transient receptor potential canonical 6 (TRPC6) channels, and transient receptor potential vanilloid 4 (TRPV4) channels. (wikipedia.org)
Echocardiography1
  • Echocardiography was done which showed Absent right pulmonary artery, small PDA with L to R shunt with peak systolic gradient of 10mm Hg, High flow in left lung, severe PAH, PFO with L to R shunt. (narayanahealth.org)
Ventilation1
  • Transient increases in ventilation for any reason may overshoot the target carbon dioxide level, causing hypocapnia. (msdmanuals.com)
Clinically1
  • After administration of terbutaline sulfate tablets, a measurable change in flow rate usually occurs within 30 minutes, and a clinically significant improvement in pulmonary function occurs within 60 to 120 minutes. (nih.gov)
Radiographic1
  • The radiographic appearance of TTN may mimic the diffuse, granular appearance of surfactant deficiency disease but usually without pulmonary underaeration. (medscape.com)
Exacerbations2
  • Exacerbations of chronic obstructive pulmonary disease contribute to the high mortality rate associated with the disease. (aafp.org)
  • 1 Exacerbations range in severity from transient declines in functional status to fatal events. (aafp.org)
Clinical1
  • In controlled clinical studies in patients given terbutaline sulfate orally, proportionally greater changes occurred in pulmonary function parameters than in heart rate or blood pressure. (nih.gov)
Respiratory distress2
  • [ 1 ] Another distinguishing factor between these 2 conditions is that neonates with transient tachypnea are usually at term, whereas surfactant deficiency disease is a cause of respiratory distress generally in premature infants. (medscape.com)
  • Initially, it may be difficult to distinguish transient tachypnea from other causes of respiratory distress. (medscape.com)
Patients3
  • Patients with isolated unilateral ''absence'' of a pulmonary artery are mostly asymptomatic, this being an incidental finding, e.g. on a chest X-ray film. (narayanahealth.org)
  • Usefulness of the pulmonary arterial systolic pressure to predict pulmonary arterial wedge pressure in patients with normal left ventricular systolic function. (umassmed.edu)
  • Therefore, most CF patients follow a specifically tailored, high-calorie diet in order to achieve normal development and maintain pulmonary health. (sensiseeds.com)
Asthma2
  • Over the past 5 yrs, various phenotypes of wheezing and asthma have been described, showing different outcomes with respect to pulmonary function. (ersjournals.com)
  • Pulmonary care provides treatment for lung and respiratory conditions, including asthma, bronchitis, certain allergies and chest wall conditions. (healthonecares.com)
Function4
  • Separate analysis of determinants of pulmonary function within these subgroups resulted in distinctly different patterns. (ersjournals.com)
  • The present results indicate that determinants of pulmonary function in 7‐yr-old children differ with respect to different wheezing phenotypes, demanding different therapeutic strategies. (ersjournals.com)
  • In studies comparing the effectiveness of terbutaline sulfate with that of ephedrine for up to 3 months, both drugs maintained a significant improvement in pulmonary function throughout this period of treatment. (nih.gov)
  • Dr. Li offers a variety of different tests including skin testing to environmental allergens and foods, skin testing to evaluate drug allergies, patch testing for contact dermatitis and pulmonary function testing. (bcm.edu)
Adult1
Disease1
  • Suspect PPHN whenever the level of hypoxemia is out of proportion to the level of pulmonary disease. (medscape.com)
Recipients1
  • In contrast, gene expression observed in oropharyngeal and nasal regions in some recipients ( B and C ) was transient. (jci.org)
Assess1
  • 0.76 yr) and harvested at 0, 3, 28, and 84 d post-exposure to assess pulmonary toxicity. (cdc.gov)
Pediatric1
  • Our pediatric pulmonary specialists treat a variety of breathing issues and even provide comprehensive allergy treatments. (healthonecares.com)
Syndrome1
  • Transient pulmonary infiltrates in a patient with Churg-Strauss syndrome (CSS). (medscape.com)
Findings1
  • Conclusion: These findings showed a limited pulmonary inflammatory potential of MWCNT at levels corresponding to the average inhalable elemental carbon concentrations observed in U.S.-based CNT facilities and estimates suggest considerable years of exposure are necessary for significant pathology to occur at that level. (cdc.gov)