• Methods: This is a cross-sectional study conducted between March 2019 and February 2020, with patients diagnosed with SCD. (scielo.br)
  • Title : Impact of the COVID-19 pandemic on blood donation and transfusions in the United States in 2020 Personal Author(s) : Basavaraju, Sridhar V.;Free, Rebecca J.;Chavez Ortiz, Joel L.;Stewart, Phylicia;Berger, James;Sapiano, Mathew R. P. (cdc.gov)
  • In accordance with the research titled 'Transfusion Services in Tropical Africa: Challenges and Prospects from the Nigerian Perspective' conducted by Sagir Gumel Ahmed in 2022, unlike other routinely tested transfusion transmissible infections such as HIV, & hepatitis B and C viruses, Cytomegalovirus is said to be highly contagious and prevalent especially in developing countries such as Nigeria. (researchgate.net)
  • Their paper, "Transfusion Utilization and Appropriateness: Thinking Differently at a Tertiary Academic Medical Center," appears in the July/August 2022 issue of the edition of the Physician Leadership Journal. (newswise.com)
  • The North America blood transfusion diagnostics market is expected to grow from US$ 1,815.82 million in 2022 to US$ 2,742.80 million by 2028. (marketresearch.com)
  • In January, 2018, Accreditation Canada added a requirement that prescribing physicians undergo competency assessment in blood transfusion (Standards for Transfusion Services 4.3), and BE Lite can help with that. (transfusionontario.org)
  • 2018 (https://www.nap.edu/catalog/25152/crossing-the- global-quality-chasm-improving-health-care-worldwide, accessed 13 February 2019). (who.int)
  • On May 25, 2023, I had the privilege of attending their annual Research Day that coincides with the Canadian Society for Transfusion Medicine (CSTM) conference. (blood.ca)
  • 10 The presence of ABO antigens on RBC surfaces requires that careful blood-typing must be carried out prior to transfusion to avoid adverse and sometimes fatal hemolytic transfusion reactions. (cap.org)
  • The field of transfusion medicine (TM) plays a crucial role in healthcare with approximately 16 million blood components transfused annually in the US, saving lives in emergencies, surgeries, cancer treatments, and various medical conditions. (cap.org)
  • Stepping into the world of research can be both exciting and overwhelming, especially as a new hire in the field of transfusion medicine. (blood.ca)
  • Fresh whole blood has long been thought of as the criterion standard for transfusion, but the advent of whole blood fractionation techniques subsequent to World War II provided a means of more efficient use of the various components (i.e., packed red blood cells [PRBCs], fresh frozen plasma [FFP], individual factor concentrates, platelet concentrates, cryoprecipitate). (medscape.com)
  • Platelet transfusions decreased from a mean 665 (±105) to a mean 595 (±47) units per month (p = .025) with a mean difference of 71 [CI = 13, 140]. (newswise.com)
  • The 12-month direct cost of pRBC and platelet transfusions decreased by $2.5 million. (newswise.com)
  • Although transfusion of donor red blood cells can ameliorate and even prevent complications of sickle cell disease in certain circumstances, transfusion therapy is not universally beneficial in sickle cell disease. (wikipedia.org)
  • Episodic transfusion is used either acutely in response to a complication of sickle cell disease such as acute chest syndrome or to prevent complications prior to surgery. (wikipedia.org)
  • Chronic transfusion is used when sustained, low levels of HbS are needed to prevent sickle cell-related complications, most commonly stroke in children. (wikipedia.org)
  • Transfusion therapy for sickle-cell disease entails the use of red blood cell transfusions in the management of acute cases of sickle cell disease and as a prophylaxis to prevent complications by decreasing the number of red blood cells (RBC) that can sickle by adding normal red blood cells. (wikipedia.org)
  • In children and adults red blood cell transfusion to increase the hemoglobin level to 100 g/L has been shown to decrease the risk of sickle cell-related complications. (wikipedia.org)
  • There is no evidence about whether or not red cell transfusions prevent chronic lung complications. (wikipedia.org)
  • Management of Patients with Sickle Cell Disease Using Transfusion Therapy: Guidelines and Complications. (sicklecelldisease.org)
  • Allergic reactions The most common complications of transfusion are Febrile nonhemolytic reactions Chill-rigor reactions The most serious complications, which have very high mortality rates, are Acute hemolytic. (merckmanuals.com)
  • Transfusion reactions describe a rare group of complications following treatment with blood and blood products which includes platelets and plasma. (hey.nhs.uk)
  • Red cell transfusions are used to treat patients with acute chest crisis and respiratory compromise. (wikipedia.org)
  • To reduce morbidity and mortality as a result of uncontrolled hemorrhage, patients needing a massive transfusion, specifically addressed in detail later in this chapter, must be quickly identified so that immediate interventions can prevent the development of the lethal triad of coagulopathy, hypothermia, and acidosis. (medscape.com)
  • 3 Today, serologic and molecular techniques, along with laboratory information systems and electronic health records, contribute to precise blood product management and personalized transfusion therapies, particularly benefiting complex patients with sickle cell disease, thalassemia, and other diseases requiring chronic transfusion support. (cap.org)
  • The researchers developed a transfusion appropriateness algorithm (TAA) to analyze blood transfusions for all adult patients at a tertiary academic medical center. (newswise.com)
  • SaskBlood is a resource developed by the Provincial Transfusion Medicine Discipline Committee to provide up-to-date resources for patients and healthcare providers. (saskblood.ca)
  • Hemanext's mission is to help patients enjoy healthier lives through safer transfusions. (sicklecelldisease.org)
  • Hemanext is focused on supporting clinicians and healthcare practitioners who prescribe life-saving RBC transfusions to their patients. (sicklecelldisease.org)
  • After excluding patients who had an intracerebral hemorrhage (ICH) or other brain injury before transfusion, and those who received blood from someone who had already had an ICH, 558,032 participants remained. (alzforum.org)
  • Clinical outcome and neurocognitive profiles of long-term survivors were also collected and compared with data from 24 patients with transfusion-dependent β-thalassaemia (TDT-β). (bmj.com)
  • Patients should also be treated (eg, with acetaminophen ) before future transfusions. (merckmanuals.com)
  • Thus, with the elevating number of patients undergoing orthopedic surgeries, the demand for blood transfusion is also rising, thereby boosting the blood transfusion diagnostic market in North America. (marketresearch.com)
  • This study sought to explore the prevalence and factors contributing to hypersplenism in transfusion-dependent thalassemia patients in the Khyber Pakhtunkhwa province of Pakistan. (jptcp.com)
  • A single-center-based retrospective study was conducted on 50 randomly selected patients over a period of three months From February 2019 to April 2019 and data was analyzed using established statistical techniques. (jptcp.com)
  • The authors previously reported that, in moderate- to high-risk cardiac surgery patients, a restrictive transfusion strategy was noninferior to a liberal strategy based on the clinical outcomes of all-cause mortality, MI, stroke, or new renal failure with dialysis. (the-hospitalist.org)
  • An adequate and safe blood supply that meets the needs of patients at all times can only be ensured through regular donations by voluntary, unpaid blood donors," Dr Al-Mandhari stated in his message on World Blood Donor Day 2019. (who.int)
  • SCD patients with fever, severe anaemia or pancytopenia should be investigated for early diagnosis and prompt treatment of IAH, which is a life- threatening haematological emergency for which transfusion therapy alone may not suffice. (bvsalud.org)
  • The authors conclude that the results support the use of barcoding and the exclusion of blood samples with even minor labeling errors in order to ensure safe blood transfusion. (ahrq.gov)
  • 13 June 2019 - On the occasion of World Blood Donor Day 2019, WHO Regional Director for the Eastern Mediterranean Dr Ahmed Al-Mandhari emphasized that everyone in the world had the right to access safe blood transfusion, when and where it was needed. (who.int)
  • Transfusion-dependent thalassemia is a chronic disease that affects many individuals and has a significant impact on the healthcare system and society. (jptcp.com)
  • These two children suffer from Thalassemia and need blood transfusion almost every fortnight. (globalgiving.org)
  • ABB conducted an Awareness Session on Thalassemia & Voluntary Blood Donation at IRISET on 23rd August 2019 followed by a Blood Donation camp on 24th August 2019 where 27 people donated blood voluntarily. (globalgiving.org)
  • How can we avoid and monitor transfusion-transmissible diseases, which are on the rise? (researchgate.net)
  • Avoiding and monitoring transfusion-transmissible diseases (TTDs) is crucial to ensure the safety of blood transfusions and protect both donors and recipients. (researchgate.net)
  • With this, why is transfusion transmissible infection (TTI) such as Cytomegalovirus not routinely tested among blood donors in several countries like Nigeria? (researchgate.net)
  • unsafe transfusion practices can put millions of people at risk of Transfusion Transmissible Infections (TTIs). (bvsalud.org)
  • Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 59 (1): 102712. (uni-giessen.de)
  • Transfusion and Apheresis Science. (jptcp.com)
  • Red blood cells (erythrocytes) from donors contain normal hemoglobin (HbA), and transfusion of normal red blood cells into people with sickle cell disease reduces the percentage of red cells in the circulation containing the abnormal hemoglobin (HbS). (wikipedia.org)
  • The safety of blood transfusion as it relates to frequency of blood donation and malaria occurrence on the part of donors is an aspect that has not been properly investigated hence this study. (who.int)
  • a cross sectional study was conducted between November 2011 to January 2012 among 594 blood donors in the Regional Blood Transfusion Center Nakuru and Tenwek Mission Hospital . (bvsalud.org)
  • Early recognition of symptoms suggestive of a transfusion reaction and prompt reporting to the blood bank are essential. (merckmanuals.com)
  • Further transfusion should be delayed until the cause of the reaction is known, unless the need is urgent, in which case type O Rh-negative red blood cells (RBCs) should be used. (merckmanuals.com)
  • Because fever and chills also herald a severe hemolytic transfusion reaction, all febrile reactions must be investigated as for acute hemolytic transfusion reaction, as with any transfusion reaction. (merckmanuals.com)
  • About 20 people die yearly in the US as a result of acute hemolytic transfusion reaction. (merckmanuals.com)
  • ABO incompatibility is the most common cause of acute hemolytic transfusion reaction. (merckmanuals.com)
  • This advice sheet has been produced to give you general information about your recent transfusion regarding the very small risk of developing a reaction. (hey.nhs.uk)
  • What are the signs of a transfusion reaction? (hey.nhs.uk)
  • If you have any concerns about a possible transfusion reaction once you have been discharged from hospital please contact the ward where you were discharged from. (hey.nhs.uk)
  • [ 1 ] Massive transfusion protocols (MTPs) should be institutionally monitored by a blood utilization committee that can track initiation, cessation, component wastage, storage of blood products outside of the blood bank, transport standards, and compliance with applicable Food and Drug Administration (FDA) standards. (medscape.com)
  • the majority of units had standardized processes for serious events (obstetric hemorrhage, massive transfusion, severe hypertension) but fewer units offered regular training on effective teamwork and communication for their staff. (ahrq.gov)
  • However, in sickle cell disease (SCD) primarily due to repeated blood transfusions and hemolysis-induced recycling of iron, its supplementation during pregnancy remains questionable and may be harmful. (scielo.br)
  • Warmed, packed RBC transfusions are used for life-threatening hemolysis and symptomatic anemia. (medscape.com)
  • Transfusion-Transmitted Infections Reported to the National Healthcare Safety Network Hemovigilance Module. (cdc.gov)
  • Transfusion-associated infections. (cdc.gov)
  • Report all cases of transfusion-transmitted infections promptly to the relevant public health authorities. (researchgate.net)
  • In children who have been given transfusions to prevent stroke there was also a reduction in the number of children who developed acute chest crises. (wikipedia.org)
  • Acute splenic and hepatic sequestration associated with severe anemia requires a simple transfusion to raise the hemoglobin. (wikipedia.org)
  • Sickle Cell Disease Association of America, Inc. (SCDAA) and Hemanext Inc., a privately held medical technology company dedicated to improving the quality, safety, efficacy and cost of red blood cell (RBC) transfusion therapy, today announced the launch of new educational material to help SCDAA deliver on its mission and meet its goals. (sicklecelldisease.org)
  • During a review of our currently available educational resources, we identified the opportunity to help young sickle cell warriors prepare for their transfusions," said SCDAA President and CEO Beverley Francis-Gibson. (sicklecelldisease.org)
  • This review discusses the use of health information technology, such as computerized provider order entry and clinical decision support systems, in transfusion medicine to enhance reliability of ordering practices and enable monitoring of adherence. (ahrq.gov)
  • Newswise - CLEVELAND -- In a new paper, researchers from University Hospitals (UH) detail how they used data via a dashboard to decrease the use of packed red-blood cell (pRBC) transfusions and platelets with an increase in appropriate transfusions. (newswise.com)
  • Lead author Jennifer Dawson, MBA, MSN, RN, said, "We hypothesized that use of an evidence-based transfusion algorithm considering patient specific criteria would raise awareness that would lead to a decrease in pRBC and platelets use, while improving appropriate use. (newswise.com)
  • The 0.7% prevalence of malaria , poses a serious health risk to non-immune recipients of transfusion. (bvsalud.org)
  • however transfusion reactions can occur within 24 hours of a transfusion whereas delayed transfusion reactions may occur more than 24 hours after a transfusion. (hey.nhs.uk)
  • citation needed] In children prophylactic chronic red blood cell (RBC) transfusion therapy has been shown to be efficacious to a certain extent in reducing the risk of first stroke or silent stroke when transcranial Doppler (TCD) ultrasonography shows abnormal increased cerebral blood flow velocities. (wikipedia.org)
  • In spite of widespread use, data supporting specific practice paradigms for whole blood and component therapy transfusion are lacking, the notable exception being in the primary treatment of hemorrhagic shock. (medscape.com)
  • Through discovery, development and applied research, Canadian Blood Services drives world-class innovation in blood transfusion, cellular therapy and transplantation-bringing clarity and insight to an increasingly complex healthcare future. (blood.ca)
  • Prompt and sustainable termination of IAH may require therapeutic combination of transfusion, anti-microbial chemotherapy, and immune modulation therapy. (bvsalud.org)
  • Transfusion transmitted malaria contributes significantly to the burden of malaria in SSA. (who.int)
  • The greatest malaria burden globally however a major risk for acquiring transfusion occurs in Nigeria, with approximately 51 million transmitted malaria. (who.int)
  • Investigate and analyze any suspected transfusion-transmitted infection cases to identify the source and prevent future occurrences. (researchgate.net)
  • 11 The promise of developing universal blood could eliminate the barrier of matching ABO antigens for blood transfusions, which is time-consuming and limits inventory. (cap.org)
  • The data analyzed in this systematic review showed that pathogen inactivation did not adversely affect the efficacy of S/D or amotosalen plasma transfusions in any patient population studied. (nih.gov)
  • However, there are also potential risks associated with an exchange transfusion: Red cell alloimmunization due to increased donor exposure Higher costs Need for specialized equipment Need for good venous access. (wikipedia.org)
  • These efforts aim to address challenges like blood shortages, alloimmunization, and improve the overall success and safety of transfusions. (cap.org)
  • Patient outcomes remained stable while transfusions decreased. (newswise.com)
  • Our findings demonstrate a significant reduction in transfusions and cost savings following implementation of the dashboards without negatively impacting patient outcomes," said lead investigator James Hill, Jr., MD, Chief Operating Officer and Critical Care Anesthesiologist at UH Parma Medical Center and Assistant Professor for the School of Medicine at Case Western Reserve University. (newswise.com)
  • Six-month outcomes after restrictive or liberal transfusion for cardiac surgery. (the-hospitalist.org)
  • citation needed] Red cell transfusions can be further classified as episodic or chronic. (wikipedia.org)
  • 4,5 As precision medicine evolves, TM continues to revolutionize patient care by optimizing transfusion strategies and minimizing risks associated with incompatible blood products. (cap.org)
  • Bloody Easy Tech Assessments (Tech Assess) is a competency program consisting of Basic and Advanced level questions intended to provide Medical Laboratory Technologists in Ontario with a mechanism to assess and build on their technical and theoretical Transfusion Medicine knowledge. (transfusionontario.org)
  • I was amazed by the depth of knowledge and creativity displayed by these future leaders in the transfusion medicine field. (blood.ca)
  • The breadth and depth of the work showcased the organization's commitment to advancing knowledge within the transfusion science medicine community. (blood.ca)
  • Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie 47 (1): 14-22. (uni-giessen.de)
  • Transfusion medicine (Oxford, England). (uni-giessen.de)
  • A consolidated report for each patient encounter showed individual transfusion data across time, including each provider who prescribed the treatments. (newswise.com)
  • ABO and Rh typing There has been a gradual decrease in overall transfusion due to patient blood management programs. (merckmanuals.com)
  • Wrong-patient errors in blood transfusion can lead to serious patient harm. (ahrq.gov)
  • Research has shown that use of barcodes to ensure correct patient identification can reduce medication errors, but less is known about barcoding in transfusion management. (ahrq.gov)
  • Hardwiring patient blood management: harnessing information technology to optimize transfusion practice. (ahrq.gov)
  • Mistakes during blood transfusion can contribute to patient harm. (ahrq.gov)
  • The anemia is usually severe with an average drop in hemoglobin of 40 g/L, and is usually treated with a simple transfusion. (wikipedia.org)
  • 90g/L), those who have not improved after a simple transfusion, or those who have severe respiratory compromise. (wikipedia.org)
  • A blood transfusion is the procedure where a person receives blood, or elements of blood usually through an intravenous infusion - meaning through a vein. (osmosis.org)
  • These procedures generally take hours, and a lot of blood is lost during the procedure, which leads to the requirement for blood transfusion. (marketresearch.com)
  • The UKTLC aims to influence positive changes within the transfusion community through the collaborative identification and promotion of best practice. (mhra.gov.uk)
  • Allogeneic transfusion of whole blood and fractionated blood components remains a controversial topic with respect to transfusion triggers and practices. (medscape.com)
  • Blood transfusion saves millions of lives every year. (who.int)
  • Ensure that regulatory agencies and blood transfusion services have clear guidelines and standards for donor screening, testing, and quality control. (researchgate.net)
  • Guidelines for the management of transfusion dependent thalassaemia (TDT). (jptcp.com)
  • Now, in rare situations, like in traumatic injuries, someone might receive a whole blood transfusion , but more commonly a person is given one of the components of the blood. (osmosis.org)
  • Transfusion Services in Tropical Africa: Challenges and Prospects from the Nigerian Perspective. (researchgate.net)
  • In 1971, hepatitis B surface antigen testing heralded the advent of screening to minimize infection transmission complicating allogeneic transfusion. (medscape.com)
  • Dr. Hill previously served at the System Medical Director of Transfusion Services and Blood Management and was the Chief of Trauma Anesthesiology at UH Cleveland Medical Center. (newswise.com)
  • It consists of two modules, module 1 focusing on the indications for blood components and products, and module 2 on the recognition and management of transfusion reactions. (transfusionontario.org)
  • Can we use them for safer transfusion? (lu.se)