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  • induces
  • Utilizing in situ hybridization techniques, we show that systemic administration of TGF alpha induces expression of these two genes in the rat intestine. (aacrjournals.org)
  • partial hepatectomy
  • TNF-alpha is also involved in cell growth accompanying the healing process in multiple organ systems and influences liver repair following hepatotoxic damage or regeneration following partial hepatectomy. (cdc.gov)
  • Expression of HGF, TGF-alpha, and aFGF was analyzed at the time of partial hepatectomy and 4, 12, 24, 48, 72, and 92 h after the operation. (aacrjournals.org)
  • cytokine
  • TNF-alpha is a pleotropic proinflammatory cytokine that has been implicated as a contributing factor in a number of disease processes, primarily through its ability to induce the expression of inflammatory and cytotoxic mediators. (cdc.gov)
  • Juxtacrine signaling has been observed for some growth factors, cytokine and chemokine cellular signals, playing an important role in the immune response. (wikipedia.org)
  • Hepatocytes
  • In this respect, TNF-alpha is a known mitogen for hepatocytes. (cdc.gov)
  • That TNF-alpha directly stimulated TGF-alpha was suggested by the inability of either anti-IL-6 Abs or cycloheximide to inhibit TNF-alpha-induced TGF-alpha expression in hepatocytes. (cdc.gov)
  • At 8 to 10 months of age, proliferative activity may become constitutive in some TGF-alpha expressing hepatocytes. (mysciencework.com)
  • induce
  • Because these regions are related to complexed signal transduction pathways mediated by cytokines, it has been proposed that cytokines and neurotropic factors can induce NK-1. (wikipedia.org)
  • Also, SP can induce the cytokines that are capable of inducing NK-1 transcription factors. (wikipedia.org)
  • inhibit
  • In addition to releasing signaling molecules into their environment to initiate quorum sensing, bacteria can use contact-dependent signaling through different mechanisms, for such purpose as to inhibit their growth in harsh conditions. (wikipedia.org)