Transferases catalyze group transfer reactions. Medical search. Frequent questions

Coenzyme A transferases (CoA-transferases) are transferase enzymes that catalyze the transfer of a coenzyme A group from an acyl-CoA donor to a carboxylic acid acceptor. (wikipedia.org)
Transferases are the class of enzymes that catalyze the transfer of various functional groups from a donner molecule to a receptor molecule. (priyamstudycentre.com)
Enzymes that catalyze the transfer of mannose from a nucleoside diphosphate mannose to an acceptor molecule which is frequently another carbohydrate. (lookformedical.com)

The chemical or biochemical addition of carbohydrate or glycosyl groups to other chemicals, especially peptides or proteins. (lookformedical.com)

Heat cannot be added to a living system, so enzymes provide an alternate pathway: they bond with a substrate (the substance involved in the chemical reaction) to form a "transition state," an unstable intermediate complex that requires less energy for the reaction to proceed. (newworldencyclopedia.org)
This region, where the binding of the substrate(s) and the reaction occur, is known as the active site of the enzyme. (newworldencyclopedia.org)
In addition, the Ions from a solution particularly cations may aid either location of substrate of the reaction. (researchwap.com)
There alterations incharge will affect substrate bonding and the resulting rate of the reaction over a narrow P.H range, this effect will be reversible but extreme acidity or alkalinity often cause serious distortion of protein structure and result in permanent denaturation. (researchwap.com)
3. SUBSTRATE CONCENTRATION: If concentration is at low substrate, the rate of reaction increases and at higher concentration the rate begins to level out and eventually becomes almost constant regardless other increase of concentration. (researchwap.com)
The structure in complex with a substrate analogue suggests a catalytic mechanism that is distinct from those of known NADases, ADP-ribosyl cyclases and transferases. (nature.com)
We also solved the structure of the enzyme bound to the reaction products, nicotinamide and ADP ribose, and the non-hydrolysable substrate analogue benzamide adenine dinucleotide (BAD). (nature.com)
The structure bound to the substrate analogue along with mutagenesis of predicted critical amino acid residues led us to suggest a reaction mechanism distinct from all known NADases. (nature.com)
One of which catalyzes the addition of double bonds and the other catalyzes the removal of groups and leaves double bonds from the substrate. (priyamstudycentre.com)
The rate of enzyme-catalyzed reactions depends on a number of factors such as pH, temperature, the concentration of enzyme, and the concentration of substrate. (priyamstudycentre.com)
Members of this family catalyze the transfer reaction of N-acetylglucosamine and N-acetylgalactosamine from the respective UDP-sugars to the non-reducing end of [glucuronic acid]beta 1-3[galactose]beta 1-O-naphthalenemethanol, an acceptor substrate analog of the natural common linker of various glycosylaminoglycans. (unl.edu)
Moreover, in hydrolytic retaining GH, yield of EVG is further diminished by secondary hydrolysis, a reaction in which the synthetic product becomes a substrate for the enzyme. (researchsquare.com)
Glycogenin initiates the biosynthesis of glycogen by incorporating glucose residues through a self-glucosylation reaction at a Tyr residue, and then acts as substrate for chain elongation by glycogen synthase and branching enzyme. (unl.edu)
Glycogenin can be classified as a retaining glycosyltransferase, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. (unl.edu)
move chemical groups (glycosyl, methyl, and phosphoryl) from one substrate to another 3. (vbook.pub)
Here we show that CobU requires a nucleoside upper ligand on cobinamide for substrate recognition, with the nucleoside base, but not the 2'-OH group of the ribose, being important for this recognition. (rhea-db.org)
a substrate site where the phosphate transfer occurs, and an allosteric site where allosteric regulation occurs. (alchetron.com)
It is proposed that the catalytic cysteine is activated by substrate binding by a proton-transfer mechanism in which the phosphate group of the nucleotide neutralizes the charge of Arg 126', facilitating the transfer of a proton from the catalytic cysteine to a His 207-Asp 205 diad via a system of ordered water molecules. (rcsb.org)
a) Enzymes that catalyse the removal of hy-drogen from a substrate but use only oxy-gen as a hydrogen acceptor to form water as a reaction product (with the exception of uricase and monoamine oxidase which form H 2 O 2 ). (biologydiscussion.com)
a) They catalyse the removal of hydrogen from a substrate and use either oxygen or artificial substances such a methylene blue as hydrogen acceptor. (biologydiscussion.com)
a) They catalyze the removal of hydrogen from a substrate but not able to use oxy-gen as hydrogen acceptor. (biologydiscussion.com)
b) They transfer hydrogen from one substrate to another by oxidation-reduction reac-tion not involving a respiratory chain (shown in Fig. 12.4. (biologydiscussion.com)

Some of the functional groups transferred by coenzymes are hydride ions, hydrogen atoms, methyl groups, and acyl groups. (pediaa.com)

Oxidoreductases: these catalyze the transfer of hydrogen or oxygen atoms or electrons and are using NAD+/NADP+ as an electron acceptor. (researchwap.com)
Oxidoreductases are the types of enzymes that catalyze oxidation reduction reactions in living cells. (priyamstudycentre.com)
Although racemases and epimerases (EC 5.1) and cis-trans isomerases (EC 5.2) are sensibly grouped according to changes of stereochemistry, the overall chemistry of intramolecular oxidoreductases (EC 5.3), intramolecular transferases (EC 5.4) and intramolecular lyases (EC 5.5) is challenging. (researchgate.net)

First, isomerases are more likely to evolve new functions in different EC primary classes, especially lyases (EC 4), rather than evolve to perform different isomerase reactions. (researchgate.net)

The main function of an enzyme is to catalyze a specific biochemical reaction inside the cell at body temperature and pH. (pediaa.com)
Their ability to catalyze a specific biochemical reaction is one of the characteristic features of an enzyme. (pediaa.com)
An enzyme refers to a substance produced by living organisms to act as a biological catalyst to bring about a specific biochemical reaction while a coenzyme refers to a non-protein compound necessary for the functioning of an enzyme. (pediaa.com)
Glycosyl transferases are used in this biochemical reaction. (lookformedical.com)
Although previous research assumes a one-to-one relationship between EC number and biochemical reaction, almost one-third of all known EC numbers are linked to more than one biochemical reaction. (researchgate.net)
Several recommendations to improve the description of complex biochemical reaction data in the EC classification were proposed. (researchgate.net)

Hydrolyses: catalyze transfer of hydrolytic reactions e.g carbonsilic ester, thiolester, endoribonuclear and dipeptile hydrolyses. (researchwap.com)
Hydrolases are the class of enzymes or biochemical catalysts which catalyze hydrolytic reactions in the biochemical process. (priyamstudycentre.com)

All enzymes are conjugated proteins and usually associated with non - proteins groups. (researchwap.com)
1. TEMPERATURE: An increase in temperature of an enzymes increase the rate of all chemical reactions include those catalyze by the enzymes, it also increases the rate of denaturation of enzymes proteins, denaturation occur more readily. (researchwap.com)
Enzymes are the biological catalyst or proteins which are produced in living organisms and speed up the chemical reactions in living cells. (priyamstudycentre.com)
Any of the enzymatically catalyzed modifications of the individual AMINO ACIDS of PROTEINS, and enzymatic cleavage or crosslinking of peptide chains that occur pre-translationally (on the amino acid component of AMINO ACYL TRNA), co-translationally (during the process of GENETIC TRANSLATION), or after translation is completed (POST-TRANSLATIONAL PROTEIN PROCESSING). (lookformedical.com)
He then joined the group of Dr. R. Sowdhamini at the National Centre for Biological Sciences in Bangalore as a visiting fellow (2002-2004), where he developed a computational method for identifying functionally important sites in proteins. (u-bordeaux.fr)
The biosynthesis of PEPTIDES and PROTEINS on RIBOSOMES, directed by MESSENGER RNA, via TRANSFER RNA that is charged with standard proteinogenic AMINO ACIDS . (lookformedical.com)
A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. (unl.edu)
The ability of proteins to carry out specific reactions is the result of their primary, secondary and tertiary structure. (studybaba.in)
In anabolism, water is removed from molecules (through energy requiring enzymatic chemical reactions) in order to grow larger molecules (e.g. starches, triglycerides and proteins for storage of fuels and information). (hmdb.ca)
Globulins are a diverse group of proteins that transport various substances in the blood. (cdc.gov)
b) They are conjugated proteins containing copper as prosthetic groups. (biologydiscussion.com)

These are hydrogenated forms of carbohydrate in which the carbonyl group (aldehyde or ketone, reducing sugar) has been reduced to a primary or secondary hydroxyl group. (ecmdb.ca)

Bilirubin is bound to glucuronic acid (conjugated) in the hepatocyte endoplasmic reticulum in a reaction catalyzed by uridine diphosphoglucuronyltransferase (UDPGT). (medscape.com)
Microsomal membrane-located uridine diphosphate (UDP) glucuronosyltransferases catalyze the transfer of an activated glucuronic acid molecule to the hydroxyl moiety of phenol to form an O-glucuronide conjugate. (selfdecode.com)

What enzyme catalyzes the conversion of phenylalanine to tyrosine? (flashcardmachine.com)
What enzyme catalyzes glutamate → glutamine? (flashcardmachine.com)
This enzyme catalyzes a transferase reaction. (planteome.org)

Hydrolases are those that catalyze the breakdown of molecules by the addition of water molecules. (studyread.com)

Bilirubin is produced in the reticuloendothelial system as the end product of heme catabolism and is formed through oxidation-reduction reactions. (medscape.com)

An enzyme is a biological catalyst that regulates the rate of a chemical reaction in a living organism. (newworldencyclopedia.org)

An enzyme that catalyzes the reversible reaction of α-d-glucose 1-phosphate UDPgalactose to produce UDPglucose and α-d-galactose 1-phosphate. (theodora.com)
It is the tri-methylated ester of L-carnitine that is formed in the mitochondria of liver, kidney, and brain cells, through a reversible acetylation reaction of carnitine catalyzed by the enzyme acetyl-carnitine transferase. (rnebiofarma.com)
An enzyme that catalyzes the reversible isomerization of D-mannose-6-phosphate to form D-fructose-6-phosphate, an important step in glycolysis. (lookformedical.com)
Leucine dehydrogenase catalyzes the reversible oxidative deamination of L-LEUCINE, to 4-methyl-2-oxopentanoate (2-ketoisocaproate) and AMMONIA, with the corresponding reduction of the cofactor NAD+. (lookformedical.com)
A PYRIDOXAL PHOSPHATE containing enzyme that catalyzes the reversible transamination of branched-chain AMINO ACIDS to 2-oxoglutarate. (lookformedical.com)

A group of enzymes that catalyze an intramolecular transfer of a phosphate group. (lookformedical.com)
In addition, the separation of groups of isomerases sharing similar chemistry such as oxidosqualene cyclases and pseudouridine synthases from chemically complex sub-subclasses like intramolecular transferases acting on \other groups' (EC 5.4.99) might also improve the classification. (researchgate.net)

Amino and amide groups from these 2 substances are freely transferred to other carbon skeletons by transamination and transamidation reactions. (medmuv.com)
The most common compounds involved as a donor/acceptor pair in transamination reactions are glutamate and α-KG, which participate in reactions with many different aminotransferases. (medmuv.com)

It is obtained by reduction of glucose changing the aldehyde group to an additional hydroxyl group. (ecmdb.ca)
It is placed in glycosyltransferase family 8 which includes lipopolysaccharide glucose and galactose transferases and galactinol synthases. (unl.edu)

In biochemistry, a ligase is an enzyme that catalyzes the formation of a chemical bond between two large types of molecules. (priyamstudycentre.com)
Nick translation is efficient for both linear and covalently closed DNA molecules, and labeling reaction are completed in less than an hour. (enzolifesciences.com)
However, other molecules can also perform enzymatic reactions - for example ribonucleic acids, RNAs. (uni-wuerzburg.de)
This family includes enzymes that transfer sugar residues to donor molecules. (unl.edu)

c) It catalyzes the oxidative deamination of the unnatural (D-) forms of amino acids. (biologydiscussion.com)
c) It catalyzes the oxidative deamination of naturally occurring L-amino acids. (biologydiscussion.com)

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. (alchetron.com)

Isomerases are the class of enzymes that catalyzes the various types of isomerization. (priyamstudycentre.com)

Like any catalyst, the enzyme remains unaltered by the completed reaction and can therefore continue to interact with substrates. (newworldencyclopedia.org)
Enzymes are usually specific, or unique, to the reactions they catalyze and the substrates that are involved in these reactions. (newworldencyclopedia.org)
A comprehensive analysis of the overall chemistry of isomerase reactions based on bond changes, reaction centres and substrates and products revealed that isomerase reactions are chemically diverse and difficult to classify using a hierarchical system. (researchgate.net)
Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. (ymdb.ca)

A genetically heterogeneous group of heritable disorders resulting from defects in protein N-glycosylation. (lookformedical.com)
Several types of carbohydrate-active enzymes (CAZymes) may be used in glycosylation reactions. (researchsquare.com)
The origin of the eukaryotic N- glycosylation pathway is not unique and less straightforward than previously thought: some basic components likely have proteoarchaeal origins, but the pathway was extensively developed before the eukaryotic diversification through multiple gene duplications, protein co-options, neofunctionalizations and even possible horizontal gene transfers from bacteria. (biomedcentral.com)

2.7.7.3) catalyzes an essential step in the reaction that transfers an adenylyl group from adenosine tri phosphate ( ATP ) to 4'-phosphopantetheine (pPant) yielding 3'- dephospho- coenzyme A (dPCoA) and pyrophosphate (PP) in the coenzyme A ( CoA ) biosynthesis pathway. (bvsalud.org)

Hepatic excretory capacity is low both because of low concentrations of the binding protein ligandin in the hepatocytes and because of low activity of glucuronyl transferase, the enzyme responsible for binding bilirubin to glucuronic acid, thus making bilirubin water soluble (conjugation). (medscape.com)
In nature, methyl groups are installed on RNAs by specialised protein enzymes. (uni-wuerzburg.de)
A transfer RNA which is specific for carrying leucine to sites on the ribosomes in preparation for protein synthesis. (lookformedical.com)
The protein part is called apo-enzyme and the non-protein part is a prosthetic group. (studyread.com)
When the individual peptide chains of secondary structure of protein are further extensively coiled and folded into sphere-like shapes with the hydrogen bonds between the amino and carboxyl group and various other kinds of bonds cross-linking on-chain to another they form tertiary structure. (studybaba.in)
Ammonia the highly toxic product of protein catabolism, is rapidly inactivated by a variety of reactions. (medmuv.com)
Though several research groups have done proteomic studies on M. tuberculosis and other members of the genus [5-7], only few researchers have utilized proteomics to determine changes in protein composition in response to the intraphagosomal environment [3-8]. (scirp.org)

Our rational design based the catalytic mechanism of the α -glucosidase reaction proved to be effective for producing mutants with improved the ratio of transglycosylation/hydrolysis of α -glucosidase, which provides an important theoretical basis for further research on the reaction mechanism of α -glucosidase. (researchsquare.com)
According to the double displacement mechanism, to increase the yield of glycoside products catalyzed by α -glucosidase, the affinity for glycosyl receptor in the deglycosylation process must be enhanced. (researchsquare.com)
In order to understand how peptides or antibiotics inhibit peptide bond formation, we must first have a clear picture of the mechanism by which ribosomes catalyze peptidyl transfer. (u-bordeaux.fr)
2014). This has led us to propose a mechanism for peptide bond formation in which the ribosome together with the A- and P-tRNAs trigger the reaction by activating a water molecule (Fig. 1). (u-bordeaux.fr)
Höbartner's group intends to solve the structure of their new ribozyme and reveal the detailed chemical mechanism of the RNA-catalyzed methylation. (uni-wuerzburg.de)
Particular emphasis is placed on classifications based on formal structural change and on reaction mechanism, and on the role of classifications within computerized reaction retrieval systems. (researchgate.net)

It has been shown in some cases that the enzyme has a functional phosphate group, which can act as the donor. (lookformedical.com)
When blood sugar is high, however, the secretion of insulin produces the opposite effect by removing the phosphate group from phosphofructokinase 2, which leads to activation, and formation of fructose 2,6-bisphosphate. (alchetron.com)

Additionally, we highlight the development of new small molecule inhibitors to target parasite acyl transferases. (imperial.ac.uk)
The MSA format was employed to study Hhat-catalyzed reactions, investigate Hhat kinetics, and determine small-molecule inhibitor IC50 values. (imperial.ac.uk)
Search chemical reactions in Rhea for this molecule. (rhea-db.org)
The molecule consists of a phenyl (-C6H5), bonded to a hydroxyl (-OH) group. (selfdecode.com)
Cytosolic phenol sulfotransferases catalyze the transfer of inorganic sulfur from the activated 3'-phosphoadenosine-5'phosphosulfate donor molecule to the hydroxyl group on phenol. (selfdecode.com)

b) Peptide bond: Amino acids are linked by a peptide bond which is between the carboxyl (- COOH) group of one amino acid and the amino (- NH 2 ) group of the next amino acid which is formed by the dehydration process. (studybaba.in)

It represents a form of storage of acetyl groups that may be associated with the Coenzyme A, necessary to trigger the Krebs cycle, thus also intervening in carbohydrate metabolism. (rnebiofarma.com)
Enzyme and coenzyme are two types of biomolecules which facilitate the occurrence of biochemical reactions in the cell. (pediaa.com)
Once bound to a chemical group, the structure of the coenzyme is changed. (pediaa.com)
Enzyme and coenzyme are essential components of the biochemical reactions that occur in the body. (pediaa.com)

The α -glucosidase (EC 3.2.1.20) Agl2 produced by Xanthomonas campestris shows high α -glucosyl transfer activity toward alcoholic and phenolic hydroxyl groups. (researchsquare.com)
c) Phosphodiester bond: This is the bond present between the phosphate and hydroxyl group of sugar which is called an ester bond. (studybaba.in)

Copper, iron, manganese, and zinc are essential transition metal ions for neurotransmission, enzymatic reactions, and mitochondrial functions regulated by the central nervous system (CNS) [ 10 ]. (hindawi.com)

This reaction is a phosphoryl group transfer from ATP to fructose 6-phosphate, yielding fructose 1,6-biphosphate. (alchetron.com)

An overview is given of the nature of, and methods for, classification of chemical reactions. (researchgate.net)
Methods to measure similarity between biochemical reactions first relied on the structure of the EC classification system (Tohsato et al. (researchgate.net)
This complexity was characterised for isomerase reactions and used to develop an approach to automatically explore it across the entire EC classification. (researchgate.net)

Enzymes are essential to sustain life because most chemical reactions in biological cells , such as the digestion of food, would occur too slowly or would lead to different products without the activity of enzymes. (newworldencyclopedia.org)

In the liver, alanine transaminase transfers the ammonia to α-KG and regenerates pyruvate. (medmuv.com)
This reaction is catalyzed by alanine transaminase, ALT. (medmuv.com)

While facilitating the enzymatic action, coenzymes serve as intermediate carriers of electrons, specific atoms or functional groups between biochemical reactions. (pediaa.com)
Furthermore, enzymes do not change their structure during the reaction while coenzymes change their structure during the reaction by binding to functional groups released from the reaction. (pediaa.com)
Attempt titrating an amino acid against a weak base and discover the number of dissociating (ionizable) functional groups in the amino acid. (studybaba.in)

Polyprenol found in animal tissues that contains about 20 isoprene residues, the one carrying the alcohol group being saturated. (lookformedical.com)
A zinc containing enzyme of the hydrolase class that catalyzes the removal of the N-terminal amino acid from most L-peptides, particularly those with N-terminal leucine residues but not those with N-terminal lysine or arginine residues. (lookformedical.com)

During the kinase reaction, both the nucleotide base and the 2'-OH group of the ribose are important for gamma-phosphate donor recognition, and GTP is the only nucleotide competent for the complete nucleotidyltransferase reaction. (rhea-db.org)

Peptide bond formation , which is catalyzed by the peptidyl transferase center located at the tunnel entrance. (u-bordeaux.fr)

Yet, a denatured enzyme can refold within fractions of a second and then precisely react in a chemical reaction. (newworldencyclopedia.org)
Like all catalysts, enzymes work to lower the activation energy of a reaction, or the initial energy input necessary for most chemical reactions to occur. (newworldencyclopedia.org)
1.1 Enzymes: These can be defined as the substances which catalyzing or alter the rate of chemical reactions. (researchwap.com)
The law of mass action states that, the rate of chemical reaction is proportional to the product of concentration of the reaction. (researchwap.com)
Like chemical catalysts, enzymes also lower the activation energy of reactions that they catalyze. (priyamstudycentre.com)
Like all chemical reactions, enzymolysis reactions are affected by changes in temperature. (priyamstudycentre.com)
In this field, the research group of chemistry professor Claudia Höbartner is now reporting a scientific breakthrough: Her team at Julius-Maximilians-Universität Würzburg (JMU) in Bavaria, Germany, has developed a ribozyme that can attach a very specific small chemical change at a very specific location in a target RNA. (uni-wuerzburg.de)
All of the chemicals discussed of this chemical was raised to carci- lung and the nasal cavity were iden- here are IARC Group 1 agents and nogenic to humans (Group 1) based tified as target organs in humans as such can be characterized as on strong mechanistic evidence and rats, respectively. (who.int)

The prosthetic group can be an inorganic part like Zn, Cu, etc., which is called a co-factor. (studyread.com)
c) It contains FAD as the prosthetic group. (biologydiscussion.com)

2nd: oxidative phosphorylation: a chain of oxidation reactions (pasapasahan ng electrons) are utilized to generate ATP. (vbook.pub)

Probes labeled by nick translation can be used in many different hybridization techniques including: chromogenic in situ hybridization (CISH), fluorescent in situ hybridization (FISH), screening gene banks by colony or plaque hybridization, DNA or RNA transfer hybridization, and re-association kinetic studies. (enzolifesciences.com)

Almost all the metabolic process is controlled by enzyme catalysis reaction. (priyamstudycentre.com)

Many enzymes can catalyze multiple reactions, whereas some enzymes are specific and catalyze only one. (wikipedia.org)
Transferases: catalyze the specific grouping transferring e.g. (researchwap.com)

Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. (lookformedical.com)

Some common reactions include Acetyl-CoA + Butyrate ⇌ {\displaystyle \rightleftharpoons } Acetate + Butyryl-CoA Acetyl-CoA + Succinate ⇌ {\displaystyle \rightleftharpoons } Acetate + Succinyl-CoA Acetoacetate-CoA + Succinate ⇌ {\displaystyle \rightleftharpoons } Acetoacetate + Succinyl-CoA Formate + Oxalate ⇌ {\displaystyle \rightleftharpoons } Formate + Oxalyl-CoA These reactions have different functions in cells. (wikipedia.org)
The reaction involving acetyl-CoA and succinate (EC 2.8.3.18) is part of a modified TCA cycle or forms acetate during fermentation. (wikipedia.org)
The reaction involving acetoacetate-CoA and succinate (EC 2.8.3.5) degrades the ketone body acetoacetate formed during ketogenesis. (wikipedia.org)

Cell apoptosis was detected by terminal deoxynucleotidyl transferase dUTP nick end labeling and Hoechst 33342 staining, and quantified by flow cytometry. (wjgnet.com)

Anatomy3

Organisms13

Chemicals and Drugs136

Analytical, Diagnostic and Therapeutic Techniques and Equipment34

Psychiatry and Psychology1

Phenomena and Processes63

Disciplines and Occupations6

Technology, Industry, Agriculture1

Information Science6

Health Care2

Enzymes that catalyze the transfer3

Glycosyl groups1

Substrate22

Acyl groups1

Oxidoreductases3

Lyases1

Biochemical reaction6

Hydrolytic reactions2

Proteins11

Carbonyl1

Uridine2

Enzyme catalyzes3

Hydrolases1

Oxidation reduction reactions1

Living organism1

Reversible5

Intramolecular2

Transamination2

Glucose2

Molecules4

Oxidative deamination2

Acceptor1

Isomerases1

Substrates4

Glycosylation3

Biosynthesis1

Protein7

Mechanism6

Phosphate group2

Molecule5

Amino acids1

Coenzyme4

Hydroxyl2

Enzymatic reactions1

Phosphoryl1

Classification3

Activity1

Alanine2

Functional3

Residues2

Donor1

Peptide1

Chemical8

Prosthetic group2

Electrons1

Kinetic1

Catalysis1

Specific2

Compounds1

Succinate3

Terminal1