• Adaptor Proteins, Signal Transducing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (childrensmercy.org)
  • This graph shows the total number of publications written about "Adaptor Proteins, Signal Transducing" by people in this website by year, and whether "Adaptor Proteins, Signal Transducing" was a major or minor topic of these publications. (childrensmercy.org)
  • Below are the most recent publications written about "Adaptor Proteins, Signal Transducing" by people in Profiles. (childrensmercy.org)
  • Signal transducing adapter molecule 1 is a protein that in humans is encoded by the STAM gene. (wikipedia.org)
  • Signal transducing adaptor molecule has been shown to interact with HGS, Janus kinase 2. (wikipedia.org)
  • Hrs is associated with STAM, a signal-transducing adaptor molecule. (wikipedia.org)
  • The action of hormones are transduced by regulating the synthesis of proteins (5% of proteins in the body are regulated by thyroid hormone). (cdc.gov)
  • These vectors have a number of appealing features including the expression by using the machinery of the host cell instead of depending abilities to ef®ciently transduce cells in the central nervous system, on recombinant regulatory proteins. (lu.se)
  • 15 We have recently conducted experiments that demonstrated enhanced in vitro survival of human T cells that were transduced with an ErbB2-specific CAR when the first and third ITAMs of the CD3-ζ domain of the CAR were inactivated. (ashpublications.org)
  • In vitro, phages can transduce resistance to imipenem, aztreonam, and ceftazidime in Pseudomonas aeruginosa ( 4 ), methicillin in Staphylococcus epidermidis ( 5 ), tetracycline in S. aureus ( 3 ) and Actinobacillus actinomycetemcomitans ( 2 ). (cdc.gov)
  • The aim of these trials was to provide patients with the protection of T-cells after T-cell-depleted allo-HSCT in the matched or mismatched donor setting with an option to delete transduced T-cells, if severe aGvHD occurred within the trial period. (frontiersin.org)
  • Donor-T-cells were transduced with the replication-deficient retrovirus SFCMM-3, expressing HSV-TK and the truncated ΔLNGFR for selection of transduced cells. (frontiersin.org)
  • Transduced cells were transfused either after day +60 (matched donors) or on day +42 (haploidentical donors). (frontiersin.org)
  • Donor chimerism was stabilized after transfusion of the transduced cells in all patients treated. (frontiersin.org)
  • Future studies with human pluripotent stem cells may transduce cells towards mesoderm and finally towards cardiac fate. (siu.edu)
  • Collectively, this study shows the importance of chemical, but also the importance of mechanical signaling to transduce cells to mesoderm. (siu.edu)
  • Transduced cells and the drug-selected KB-8-5-11 and C3M cell lines were incubated with 1.5 M Rh123 either alone (gray bars) or in combination with the P-gp modulators. (unscburma.org)
  • We transduced all six cell types with fluorescent histone Mouse monoclonal to HER-2 2B (H2B) like a nuclear marker as well as the CDK2 activity sensor and monitored CDK2 activity by time-lapse imaging and cell tracking in asynchronously cycling cells. (biopaqc.com)
  • In vivo tracking of adenoviral-transduced iron oxide-labeled bone marrow-derived dendritic cells using magnetic particle imaging. (bvsalud.org)
  • KEY POINTS â ¢ Adenoviral-transduced and iron oxide -labeled dendritic cells are in vivo migration competent. (bvsalud.org)
  • PD-L1 binding assays were performed using the transduced PD-L1-expressing lymphoma cell line U-698-M and wild-type U-698-M cells as a negative control. (snmjournals.org)
  • To evaluate anti-CD19-CAR-transduced T cells in a murine model of adoptive T-cell therapy, we developed a CAR that specifically recognized murine CD19. (ashpublications.org)
  • We used T cells that were retrovirally transduced with this CAR to treat mice bearing a syngeneic lymphoma that naturally expressed the self-antigen murine CD19. (ashpublications.org)
  • One infusion of anti-CD19-CAR-transduced T cells completely eliminated normal B cells from mice for at least 143 days. (ashpublications.org)
  • Anti-CD19-CAR-transduced T cells eradicated intraperitoneally injected lymphoma cells and large subcutaneous lymphoma masses. (ashpublications.org)
  • The antilymphoma efficacy of anti-CD19-CAR-transduced T cells was critically dependent on irradiation of mice before anti-CD19-CAR-transduced T-cell infusion. (ashpublications.org)
  • Anti-CD19-CAR-transduced T cells had superior antilymphoma efficacy compared with the anti-CD19 monoclonal antibody from which the anti-CD19 CAR was derived. (ashpublications.org)
  • Our results demonstrated impressive antilymphoma activity and profound destruction of normal B cells caused by anti-CD19-CAR-transduced T cells in a clinically relevant murine model. (ashpublications.org)
  • To establish a murine model in which a completely syngeneic lymphoma could be treated by adoptive transfer of syngeneic CAR-transduced T cells, we developed a CAR that could specifically recognize murine CD19. (ashpublications.org)
  • There are a number of hypothesized that regulating the transgene with a GFAP promoter in a different vectors that transduce cells in the brain in a slightly different viral vector would give rise to a high transgenic expression in the manner (for a review see, e.g. (lu.se)
  • The BD FACS Melody is contained within a biosafety hood which makes it suitable for sorting primary human samples and transduced cells. (lu.se)
  • Methods for host-independent detection of transducing phage particles have recently been described. (cdc.gov)
  • Gene-transduced hepatocytes with E1/E3-deleted adenoviral vectors are eliminated immediately and the expression of transduced genes disappears rapidly following the vector administration. (elsevierpure.com)
  • Lambda transducing phages for the nalA gene of Escherichia coli and conditional lethal nalA mutations. (yale.edu)
  • Although significant progress has been made in understanding the mechanisms linking the cell cortex to the spindle and the well-documented role that extracellular forces play in spindle orientation, how such forces are transduced to the cortex remains poorly understood. (ucy.ac.cy)
  • transduce (v.) transduct (v.) transduction (n. (github.io)
  • This variation in cytosolic domains is responsible for the wide range of cellular and environmental signals sensed and transduced by TRP channels. (lu.se)
  • She deutschland revatio names unable, transduced governed hypersensitivity, metabolism. (dementiewijzerdelft.nl)
  • They can also transduce resistance genes from Salmonella enterica serovar Typhimurium DT104 ( 1 ). (cdc.gov)
  • Constructs were transduced to express human VEGF165 by baculoviral (BV) system. (biomedcentral.com)
  • In this work we report on therapeutic efficacy of CS from mouse ADSC transduced to express human vascular endothelial growth factor 165 a/a isoform (VEGF165), which showed potency to restore perfusion and protect tissue in a model of limb ischemia. (biomedcentral.com)
  • 2002 until 2007), two were included in TK007 (2005-2009) and six serves as a control group for outcome after haploidentical transplantation without HSV-TK-transduced DLI. (frontiersin.org)
  • Significant vascularization of CS and infiltration by monocytes were found in both - BV-transduced and control CS indicating graft and host interaction after transplantation. (biomedcentral.com)
  • Adenovirus (Ad)-transduced SPIO+ (Ad SPIO+) and SPIO+ C57BL/6 bone marrow -derived DC were generated and assessed for viability and phenotype , then fluorescently labeled and injected into mouse hind footpads (n = 6). (bvsalud.org)
  • Thus, we propose that the disordered CadC linker is required for transducing the pH-dependent response of the periplasmic sensor into a structural rearrangement that facilitates dimerization of the cytoplasmic CadC DNA-binding domain. (cipsm.de)
  • Signal transducing adaptor molecule has been shown to interact with HGS, Janus kinase 2. (wikipedia.org)
  • Hrs is associated with STAM, a signal-transducing adaptor molecule. (wikipedia.org)
  • Adaptor Proteins, Signal Transducing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ctsicn.org)
  • This graph shows the total number of publications written about "Adaptor Proteins, Signal Transducing" by people in this website by year, and whether "Adaptor Proteins, Signal Transducing" was a major or minor topic of these publications. (ctsicn.org)
  • Below are the most recent publications written about "Adaptor Proteins, Signal Transducing" by people in Profiles. (ctsicn.org)
  • We found that an adaptor protein, signal-transducing adaptor protein (STAP)-2, is a new member of the Fas-death-inducing signaling complex and participates in activation-induced cell death in T cells. (elsevierpure.com)
  • Signal-transducing adaptor protein 1 (STAP1) in microglia promotes the malignant progression of glioma. (bvsalud.org)
  • Moreover, signal-transducing adaptor protein 1 (STAP1) plays a role in tumourigenesis and immune responses . (bvsalud.org)
  • Signal transducing adapter molecule 1 is a protein that in humans is encoded by the STAM gene. (wikipedia.org)
  • Enzyme IIA(Glucose) (IIA(Glc)) is a signal-transducing protein in the phosphotransferase system of Escherichia coli. (nih.gov)
  • In an ischemic animal model, Tat-AR protein transduced into the brain tissues through the blood-brain barrier (BBB) and drastically decreased neuronal cell death in hippocampal CA1 region. (en-journal.org)
  • These results indicate that transduced Tat-AR protein has protective effects against oxidative stress-induced neuronal cell death in vitro and in vivo , suggesting that Tat-AR protein could be used as potential therapeutic agent in ischemic injury. (en-journal.org)
  • Vav1 is a signal transducing protein necessary for T cell receptor (TCR) indicators that drive negative and positive selection in the thymus. (careersfromscience.org)
  • Primary cultures of Barrett's esophageal epithelium transduced with a retrovirus containing hTERT were characterized by growth factor requirements, cytogenetics and flow cytometry. (nih.gov)
  • A small defective generalized transducing bacteriophage (CA3) has been detected in culture supernatants of the nitrogen-fixing hydrogen bacterium Xanthobacter autotrophicus GZ29. (microbiologyresearch.org)
  • Discovery, purification, and characterization of a temperate transducing bacteriophage for Bordetella avium. (ncsu.edu)
  • However, compared to freshly isolated brain capillaries or primary BCECs, the expression of Pgp in immortalized BCEC lines is markedly lower, which prompted us previously to transduce the widely used human BCEC line hCMEC/D3 with a doxycycline-inducible MDR1 -EGFP fusion plasmid. (biomedcentral.com)
  • Localization, trafficking, and function of Pgp were compared in WT and MDR1 -EGFP transduced cell lines. (biomedcentral.com)
  • They can also transduce resistance genes from Salmonella enterica serovar Typhimurium DT104 ( 1 ). (cdc.gov)
  • Extended lifespan of Barrett's esophagus epithelium transduced with the human telomerase catalytic subunit: a useful in vitro model. (nih.gov)
  • The representative images of typical neurons and neurons treated with Tat86 or Tat86 plus Hutat2:Fc containing mediums in the transduced hMDM are shown in Figure 4A. (icbinhibitor.com)
  • Compared with Tat exposure alone, the relative price of neuron survival was improved by ten , from 69.three eight.9 to 79.four 7.9 in the presence of conditioned medium from HR-Hutat2-transduced hMDM (P 0.05). (icbinhibitor.com)