Loading...
  • protein
  • MBD2 is a DNA repair protein and therefore unlikely to be involved in transcriptional repression. (bl.uk)
  • The present study shows that pharmacologic concentration of diallyl trisulfide (DATS), a highly promising cancer chemopreventive constituent of garlic, decreases protein level of AR in LNCaP and C4-2 human prostate cancer cells by causing its transcriptional repression. (aacrjournals.org)
  • These results indicate that the accumulation of p300 protein participates in repression of the SV40 enhancer activity in undifferentiated F9 cells. (aacrjournals.org)
  • deacetylation
  • The repression by this novel domain was found to be sensitive to TSA, suggesting that deacetylation may again be involved. (bl.uk)
  • interacts
  • Wnt signaling allows the translocation of cytoplasmatically tethered β-catenin into the nucleus, where it directly interacts with LEF-1, stimulating LEF-1-dependent transcriptional activation ( 19 ). (pnas.org)
  • Cell
  • Treatment of early-stage melanomas expressing low levels of PKCɛ with chemotherapies relieves ATF2-mediated transcriptional repression of IFNβ1, resulting in impaired S-phase progression, a senescence-like phenotype and increased cell death. (nih.gov)