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  • permissive
  • Besides this structural part in organising the RNP complex, NP has been implicated in the rules of transcription and replication of influenza disease, as several temperature-sensitive NP mutations have been identified that result in defective replication at non-permissive temps26,27. (biotech2012.org)
  • Klf4
  • The reprogramming process is just the opposite by inducing a set of reprogramming factors (such as Oct3/4, Sox2, c-Myc and Klf4 [ 9 ]) to push the system going up with positive probability. (biomedcentral.com)
  • regulator
  • We report that Arabidopsis homologue of spliceosome disassembly factor NTR1 is required for correct expression and splicing of DOG1 , a regulator of seed dormancy. (embopress.org)
  • p300
  • During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. (genecards.org)
  • embryonic
  • Differentiated cells are reprogrammed to induced-pluripotent stem cells (iPSC) by ectopic expression of factors which induce the reestablishment of transcription regulation in embryonic stem cell state. (biomedcentral.com)
  • facilitate
  • We demonstrate that RNA inhibition of transcription factors can facilitate reprogramming, and that treatment with DNA methyltransferase inhibitors can improve the overall efficiency of the reprogramming process. (nih.gov)
  • polymerase
  • GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and transcription factor activity, RNA polymerase II core promoter sequence-specific . (genecards.org)
  • The induction of apoptosis after PLK1 silencing was confirmed by increased p-H2AX, propidium iodide uptake, and chromatin condensation, as well as caspase-3 and poly(ADP-ribose) polymerase cleavage. (aacrjournals.org)
  • AtNTR1, the Arabidopsis homologue of spliceosome disassembly factor NTR1, is required for pausing of RNA polymerase II at strong alternative splicing sites. (embopress.org)
  • mutation
  • Epidermal growth factor receptor (EGFR) activation by amplification or mutation is one of the most frequent genetic lesions in a variety of human tumors. (rupress.org)
  • replication
  • To be able to investigate what function, if any, NP has in the legislation of replication and transcription, we constructed some brief genome segments predicated on gene portion 5 by inner deletions, minimally keeping the conserved 3 and 5 termini as well as the oligo(U) stretch out near the 5 terminus (Supplementary Fig. S1). (biotech2012.org)