• Children's Hospital of
  • Young investigators are invited to present posters at the 8th Annual Friedreich's Ataxia Symposium hosted by The Children's Hospital of Philadelphia (CHOP) and FARA at a welcome reception on the evening of Sunday, October 11, and throughout the day on Monday, October 12, 2015 at the DoubleTree hotel in King of Prussia, PA. (curefa.org)
  • findings
  • 1. These findings suggest a therapeutic potential of CHOP inhibition in the management of diabetic cardiovascular complications including diabetic cardiomyopathy. (igib.res.in)
  • cell
  • 1. In vivo knockdown of ORP150 induced DPN in early diabetes and exacerbated the DPN after prolonged diabetes, whereas knockdown of CHOP ameliorated DPN in rats with prolonged diabetic.In the early stage of diabetes, CHOP/ORP150 ratio was relatively low favoring neuronal cell survival, whereas after prolonged diabetes, CHOP/ORP150 ratio increased resulting in apoptotic cell death leading to accelerated (diabetic peripheral neuropathy) DPN. (igib.res.in)