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  • family
  • However, a HD3 systemic evaluation of the manifestation of all AP-1 family members as potential biomarkers in breast cancer is still lacking. (healthweblognews.info)
  • phosphorylation
  • In addition, both 4d and 4e inhibited LPS-induced DNA binding activities of NF-κB and AP-1 and phosphorylation of p38 MAPK without affecting other MAP kinases. (nih.gov)
  • novel
  • We identified with bioinformatics tools that a novel AP-1 site at -1363 bp of human TF promoter region is highly conserved across multiple species. (ahajournals.org)
  • role
  • Taken together, these results suggest that p38 MAPK plays an important role in the anti-inflammatory effects of 4d and 4e via the modulation of NF-κB and AP-1 activities. (nih.gov)
  • bind
  • Coexpression of Sp1, NFI, and AP-1 was demonstrated in all cell types, and each TF was shown to bind efficiently to the α5 promoter. (ulaval.ca)
  • site
  • This work is concerned with the synthesis of DNA anchored cysteinyl peptides designed to be potentially nucleotide sequence specific with possible affinity for the AP-l transcription site. (dmu.ac.uk)