Transcription factor 7 interacting protein. Medical search. Frequent questions

At the cellular level, the actions of glucocorticoids are mediated by a 94-kd protein, the glucocorticoid receptor (GR). The human (h) GR belongs to the steroid/thyroid/retinoic acid superfamily of nuclear receptors and functions as a ligand-dependent transcription factor that regulates the expression of glucocorticoid-responsive genes positively or negatively. (medscape.com)
Rhombotin 1 (RBTN1 or TTG-1) and rhombotin-2 (RBTN2 or TTG-2) are proteins of about 160 amino acids whose genes are disrupted by chromosomal translocations in T-cell leukemia. (embl.de)
Interacts with the DNA specific motifs of giberrellin-up-regulated genes of anthers and regulates their expression. (gao-lab.org)
In humans, the CRYAA gene encodes a 173 amino acid residue protein by single copy genes located on chromosome 21. (molvis.org)
p53 affects the transcription of many target genes and interacts with key cellular proteins. (molvis.org)
We then investigated expression levels of genes involved in BMP signaling and regulation (for example, Smad1/5/8, TGFβ receptors type I and II, noggin, sclerostin, BMP and activin receptor membrane bound inhibitor (BAMBI), v-ski sarcoma viral oncogene homolog (Ski), Ski-related novel protein N (SnoN) and Smad ubiquitination regulatory factors (Smurfs)) and confirmed the expression of regulated genes at the protein level. (biomedcentral.com)
Our data suggest that both the A-tract and C-rich segment within the VRN-box contribute to its functionality, and provide a new view of the hypothesised role of the VRN-box in regulating transcription of the VRN1 genes. (biomedcentral.com)
One of the key factors governing the adaptability of wheat to a wide range of environmental conditions is allelic diversity within genes regulating seasonal growth habit (vernalization requirement) and photoperiod response. (biomedcentral.com)
Genes for proteins interacting with other hormones may have a greater effect. (cdc.gov)
These dCas9-activator fusions targeted to the promoter region of endogenous genes can then modulate gene expression 7 - 11 . (cdc.gov)

ATF7IP is a recruiter protein that couples transcriptional factors to the general transcription apparatus, thereby modulating transcription regulation and chromatin formation. (wikipedia.org)
The AF-1 plays an important role in the interaction of the receptor with molecules necessary for the initiation of transcription, such as coactivators, chromatin modulators, and basal transcription factors, including RNA polymerase II, TATA-binding protein (TBP), and a host of TBP-associated proteins (TAFIIs). (medscape.com)
Chromatin remodelling and transcription factors play important roles in lineage commitment and development through control of gene expression. (ox.ac.uk)
However, the complex functional and physical interplay between transcription factors and chromatin-modifying enzymes remains elusive. (ox.ac.uk)
Chromatin immunoprecipitation showed that LaTRF interacted specifically with telomeres in vivo . (biomedcentral.com)
Mechanistically, the CHD4M195I protein showed augmented affinity to endocardial BRG1 (SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily A, member 4). (bvsalud.org)
Nuclear proteins bind chromatin to execute and regulate genome-templated processes. (bvsalud.org)

Transforming growth factor β1 inhibits bone morphogenic protein (BMP)-2 and BMP-7 signaling via upregulation of Ski-related novel protein N (SnoN): possible mechanism for the failure of BMP therapy? (biomedcentral.com)

Among all JA downstream transcription factors, MYC2 is considered as the fatal point of the entire JA signaling pathway ( Kazan and Manners, 2013 ). (frontiersin.org)
Discussion at the Vancouver meeting spanned several areas of research, including signaling pathway activation of EMT and the transcription factors and gene targets involved. (rupress.org)

Isl-1 binds to one of the two cis-acting protein-binding domains of the insulin gene. (embl.de)
Mdm2 binds directly to the transcriptional activation domain of p53 and blocks p53-dependent transcription. (molvis.org)

Originally discovered as a chief regulatory protein of glucose and lipid metabolism and cell differentiation, the peroxisome proliferator-activated receptor gamma (PPARγ) is a ligand-activated transcription factor of the nuclear hormone receptor superfamily 8 . (nature.com)
a protein required for the differentiation of the set of six touch receptor neurons in this nematode. (embl.de)
The effects of POP inhibition and knockdown on the proliferation of cultured human estrogen receptor-positive (ER+) MCF7 and T47D, and ER-negative (ER-) MDA-MB-231 breast cancer cell lines and the MCF12A non-tumorigenic epithelial cell line were tested by analyzing their influence on cell proliferation (WST-1 assay), cell viability (trypan blue exclusion assay), and cell cycle arrest (cell cycle analysis, cell cycle regulator proteins expression). (cancerindex.org)
The androgen receptor (AR) is a ligand-dependent transcription factor that has an essential role in the normal growth, development, and maintenance of the prostate gland. (nih.gov)
However, these receptors exhibit a high degree of sequence variability at their NH(2)-terminal domain, which suggests the possibility of receptor-specific interactions with co-regulator proteins. (nih.gov)
3.0: hematopoietic cell-specific Lyn substrate 1 (HCLS1), Kelch domain-containing 6 (KLHDC6), sarcoglycan delta (SGCD), KIAA1706 protein (KIAA1706), RNA guanylyltransferase and 5′-phosphatase (RNGTT), chromosome 10 open reading frame 57 (C10orf57), chromosome 9 open reading frame 52 (C9orf52), and plasminogen activator, urokinase receptor (PLAUR). (molvis.org)
G protein-coupled receptor 87 [Source:H. (gsea-msigdb.org)
G protein-coupled receptor kinase 5 [So. (gsea-msigdb.org)

This gene encodes a basic motif-leucine zipper transcription factor of the Maf subfamily. (en-academic.com)

MSY3 is a DNA binding protein, which acts as a transcriptional repressor. (biomedcentral.com)

A comparative analysis was performed in the present study in TNBC (HCC1143) and non‑TNBC (MCF‑7) cell lines to explore the effect of 3‑BrPA on energy metabolism in TNBC cells and to investigate the possible mechanism of action. (spandidos-publications.com)
MSY3 (MSY4, YB-2, CSDA, dbpA, ZONAB) is a member of the cold shock domain (CSD) family of proteins also known as Y-box proteins, which are evolutionarily conserved proteins that function as transcription factors and regulators of RNA metabolism and protein synthesis. (biomedcentral.com)

The glutamine-rich protein 1 is 776 amino acids in length. (wikipedia.org)
Glutamine residues are abundant, comprising 109 of the amino acids or 14% of the protein. (wikipedia.org)
The C-terminal sequence of 220 amino acids is named the Mage homology domain (MHD) and contains 25 repeats of a WQXPXX sequence in the middle region 7 - 10 . (researchsquare.com)
The active full-length CRYAA protein corresponding to amino acids 1-173 of CRYAA was recombined. (molvis.org)

The second domain is a glutamine-rich domain which comprises a majority of the protein and is highly conserved among orthologs. (wikipedia.org)
The 14-3-3 proteins are highly conserved in all eukaryotes. (elifesciences.org)
The Y-box protein MSY3/Csda represses myogenin transcription in skeletal muscle by binding a highly conserved cis-acting DNA element located just upstream of the myogenin minimal promoter (myogHCE). (biomedcentral.com)

We combined time-lapse microscopy, highly multiplexed single-cell imaging of 48 core cell cycle proteins, and manifold learning to render a visualization of the human cell cycle. (bvsalud.org)

The histone H3K4 demethylase JARID1A directly interacts with haematopoietic transcription factor GATA1 in erythroid cells through its second PHD domain. (ox.ac.uk)
Here, we use nucleosome affinity proteomics with a library of nucleosomes that disrupts all exposed histone surfaces to comprehensively assess how proteins recognize nucleosomes. (bvsalud.org)

It is, however, thought to be involved in processes such as inflammation and apoptosis due to the presence of a CARD domain near the beginning of the protein sequence. (wikipedia.org)
[ 6 ] NF-KB protects cells from apoptosis in response to tumor necrosis factor-alpha (TNF-alpha). (medscape.com)
Expression levels of HK2, glucose transporter 1, TXNIP, c‑Myc and mitochondria‑regulated apoptosis pathway proteins were measured through western blotting. (spandidos-publications.com)
The present results suggested that 3‑BrPA promoted TXNIP protein expression and reduced HK2 expression in TNBC cells by downregulating c‑Myc expression, inhibiting glycolysis including suppressing lactate generation, intracellular ATP generation and HK activity, inducing mitochondrial‑mediated apoptosis and eventually suppressing TNBC cell proliferation. (spandidos-publications.com)
Thus the inhibitory effects of SLTM on gene expression appear to result from generalized down-regulation of mRNA synthesis and initiation of apoptosis consequent upon overexpressing the protein. (bris.ac.uk)

The ZPA secretes a protein, Sonic Hedgehog (SHH), which regulates the AP axis. (medscape.com)

Various growth factors, cytokines, and extracellular matrix proteins are substrates for meprins. (embl-heidelberg.de)
Proliferation of cardiomyocytes was significantly increased in CHD4M195I hearts, and the excessive trabeculation was associated with accumulation of ECM (extracellular matrix) proteins and a reduction of ADAMTS1 (ADAM metallopeptidase with thrombospondin type 1 motif 1), an ECM protease. (bvsalud.org)
Osteoblast-Specific Factor 2 (OSF-2, Periostin) is a secreted extracellular matrix protein (ECM) expressed in fibroblasts during bone and teeth development. (morulaivf.com)

Studies have confirmed that Mage-D1 can interact with a variety of proteins through its three domains 11 . (researchsquare.com)
Meprins are mammalian tissue-specific metalloendopeptidases of the astacin family implicated in developmental, normal and pathological processes by hydrolysing a variety of proteins. (embl-heidelberg.de)

TcMYC2a was also found to bind with TcJAZ3 in yeast, which was a homolog of Arabidopsis JASMONATE ZIM-domain JAZ proteins, indicating that TcMYC2a had a similar function to AtMYC2 of JA signal transduction. (frontiersin.org)
Saccharomyces cerevisiae (Baker's yeast) rho-type GTPase activating protein RGA1/DBM1. (embl.de)
Here we have identified Ran-binding protein in the microtubule-organizing center (RanBPM) to be a novel AR-interacting protein by yeast two-hybrid assay and have confirmed this interaction by glutathione S-transferase- and His-tagged pull-down assays. (nih.gov)

QRICH1 has five paralogs all of which encode a zinc finger protein. (wikipedia.org)
LIM domains coordinate one or more zinc atoms, and are named after the three proteins (LIN-11, Isl1 and MEC-3) in which they were first found. (embl.de)
Zinc finger (Znf) domains are relatively small protein motifs which contain multiple finger-like protrusions that make tandem contacts with their target molecule. (embl.de)
Mammalian cysteine-rich intestinal protein (CRIP), a small protein which seems to have a role in zinc absorption and may function as an intracellular zinc transport protein. (embl.de)
Among the established custom DNA binding domains, Cas9 is most easily scaled to facilitate genome-scale perturbations 3 , 4 due to its simplicity of programming relative to zinc finger proteins and transcription activator-like effectors (TALEs). (cdc.gov)

[ 2 ] The defect in the X chromosome is proximal to the gene for factor VIII at Xq28. (medscape.com)
This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. (cancerindex.org)
The mammalian TRF1 and TRF2 proteins, for example, bind double-stranded telomeres via a Myb-like DNA-binding domain and are involved with telomere length regulation and chromosome end protection. (biomedcentral.com)
These complexes, which are abundant at chromosome ends but do not accumulate elsewhere, are present at telomeres throughout the cell cycle and their action is limited to telomeres [ 7 , 8 ]. (biomedcentral.com)

Basic helix-loop-helix (bHLH) myogenic regulatory factors coordinate the correct function and organization of many skeletal muscle functions. (biomedcentral.com)

The HuProt microarray results showed that the signals of 343 proteins were higher in the recombinant CRYAA group than in the control group. (molvis.org)
Consequently, it was expected that topical application of recombinant human (rh)BMP-2 and rhBMP-7 would improve the healing of complex fractures. (biomedcentral.com)
The biological activity of recombinant human (rh)BMPs (2, 4 and 7) has been defined by using a variety of animal models. (biomedcentral.com)
Expression of the L1 protein using recombinant DNA technology produces noninfectious virus-like particles (VLPs). (cdc.gov)

Blocking the interaction between PIF7 and 14-3-3 proteins or reducing the expression of 14-3-3 proteins accelerates shade-induced nuclear localization and de-phosphorylation of PIF7, and enhances the shade phenotype. (elifesciences.org)
Here, we report an interaction between H3K4 demethylase JARID1A and the haematopoietic-specific master transcription proteins SCL and GATA1 in red blood cells. (ox.ac.uk)
The antiadipogenic mechanism of endostatin lies in its interaction with Sam68 RNA-binding protein in the nuclei of preadipocytes. (diabetesjournals.org)
For example, TRF1 can control telomerase access through its interaction with TIN2, PTOP/PIP1 and the single-stranded telomeric DNA-binding protein POT1. (biomedcentral.com)

in 1999 7 . (researchsquare.com)

11 Advances in Radiopharmaceutical Development and New Trends in Radiochemistry Molecular imaging (using fotex PET payapl SPET radiotracers) will encompass in the future imaging of gene expression, protein expression, often referred to as an expiry date, the stock is trading at above 100, 1,000 is received. (forextrading-madeeasy.com)
We recently reported a procedure for inferring gene-regulatory network models by integrating gene-expression profiles with high-throughput measurements of protein interactions [ 18 ]. (biomedcentral.com)
Scope includes mutations and abnormal protein expression. (cancerindex.org)
Although the expression of MHC class I and II molecules can be upregulated by MSC exposure to inflammatory cytokines interferon-gamma (IFN- γ ) and tumor necrosis factor-alpha (TNF- α ), they are still unable to induce an immunological response [ 18 ]. (hindawi.com)
Hexokinase 2 (HK2) is a key enzyme in the glycolytic pathway and a target of the transcription factor c‑Myc, which is highly expressed in TNBC and promotes aerobic glycolysis by enhancing HK2 expression. (spandidos-publications.com)
Expression of transcription factor CITED4 is necessary for exercise-induced regional remodeling of the heart's microstructural helicity, revealing how a key molecular regulator of cardiac remodeling mediates local tissue-level changes. (researchgate.net)
Immunohistochemical analysis of 78 colon cancer patients showed that the high expression levels of ACLY and CTNNB1 protein was positively correlated with metastasis of colon cancer. (biomedcentral.com)
Gene expression was determined by reverse transcription polymerase chain reaction (RT-PCR) and confirmed at the protein level by western blot. (biomedcentral.com)
As possible mechanism, we postulate an induction of SnoN that increases HDAC activity and thereby reduces the expression of factors required for efficient BMP signaling. (biomedcentral.com)
While indicating a crucial role for SLTM in cellular function, these results also emphasize the need for caution when interpreting phenotypic changes associated with manipulation of protein expression levels. (bris.ac.uk)
Expression of Osteoblast - Specific Factor 2 (OSF- 2 , Periostin) Is Associated with Drug Resistance in Ovarian Cancer Cell Lines. (morulaivf.com)
The OSF-2 transcript (real-time PCR analysis), protein expression in cell lysates and cell culture medium (western blot), and expression of the OSF-2 protein in cell lines (immunofluorescence) were investigated in this study. (morulaivf.com)
Increased expression of OSF-2 mRNA was observed in drug-resistant cells and followed by increased protein expression in cell culture media of drug-resistant cell lines. (morulaivf.com)
Transcription factors (TFs) are critical for B-cell differentiation, affecting gene expression both by repres- sion and transcriptional activation. (lu.se)
The identified transcription factors influence both the global and specific gene expression of the BCLs and have possible implications for diagnosis and treat- ment. (lu.se)
En-1 blocks Wnt-7a expression, preventing expression of Lmx-1b there, and establishes the dorsal-ventral axis. (medscape.com)
Conversely, hnRNPA1 overexpression reduced NP expression at the mRNA and protein levels and impeded virus replication by (60.70%), suggesting antagonistic function. (cdc.gov)
Programmable DNA binding proteins have emerged as an exciting platform for engineering synthetic transcription factors for modulating endogenous gene expression 5 - 11 . (cdc.gov)

An inhibitory molecule of the IKB family interacts with NF-KB to sequester it in the cytoplasm. (medscape.com)
In Trp53KO/C-MycOE mice and mice with tumors grown from Hepa1-6 cells, injection of the combination of anti-PD1 and anti-TIGIT significantly reduced tumor growth, increased the ratio of cytotoxic to regulatory T cells in tumors, and prolonged survival.PVRL1, which is up-regulated by HCC cells, stabilizes cell surface PVR, which interacts with TIGIT, an inhibitory molecule on CD8+ effector memory T cells. (stanford.edu)
Addition of an HDAC inhibitor, namely valproic acid, fully abolished the inhibitory effect of rhTGFβ 1 on rhBMP-2 and rhBMP-7 signaling. (biomedcentral.com)
Although SLTM also suppressed the ability of oestrogen to activate a reporter gene in MCF-7 breast-cancer cells, inhibition of a constitutively active beta-galactosidase gene suggested that this was primarily the consequence of a generalized inhibitory effect on transcription. (bris.ac.uk)

This generally yields a large library of DNA sequences, including some that were bound by the transcription factor directly, some that were bound indirectly via interactions with other molecules, and some false positives (such as cases of nonspecific binding). (ucsc.edu)
A target that has fewer human similarity proteins outside its family is commonly regarded to possess a greater capacity to avoid undesired interactions and thus increase the possibility of finding successful drugs ( Brief Bioinform, 21: 649-662, 2020 ). (idrblab.net)
We find that the acidic patch and two adjacent surfaces are the primary hot-spots for nucleosome disk interactions, whereas nearly half of the nucleosome disk participates only minimally in protein binding. (bvsalud.org)
To identify proteins interacting with alpha A-crystallin (CRYAA) and to investigate the potential role that these protein interactions play in the function of CRYAA using a human proteome (HuProt) microarray. (molvis.org)
A HuProt microarray composed of 17,225 human full-length proteins with N-terminal glutathione S-transferase (GST) tags was used to identify protein-protein interactions. (molvis.org)
The protein-protein interactions may help CRYAA carry out multifaceted functions. (molvis.org)
To understand the functions of CRYAA and how these are regulated, protein-protein interactions need to be investigated. (molvis.org)

For example, some proteins activate transcription by recruiting RNA polymerase, some repress transcription by suppressing this recruitment, and others insulate proximal regions from the activity of nearby transcriptional activators or repressors. (ucsc.edu)
Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. (idrblab.net)

Vertebrate protein kinases LIMK-1 and LIMK-2. (embl.de)
They promote cell survival by the activation of downstream protein kinases and, finally, transcription factors of the NF-kB and AP-1 family. (embl-heidelberg.de)

In Arabidopsis , the shade-induced de-phosphorylation of the transcription factor PIF7 (PHYTOCHROME-INTERACTING FACTOR 7) is the key event linking light perception to stem elongation. (elifesciences.org)

The encoded protein is conserved among vertebrates and is a critical intrinsic regulator of photoceptor development and function. (en-academic.com)
p53 E3 ubiquitin protein ligase homolog (Mdm2) is an important negative regulator of p53. (molvis.org)
These cells express the master regulator transcription factor (TFs) Foxp3. (encyclopedia.pub)

We previously reported that human MMP3 could translocate into cellular nuclei and control transcription in human chondrosarcoma-derived cells and in articular cartilage (Eguchi et al. (elsevierpure.com)

The NEMO protein is required for the activation of the kinase complex. (medscape.com)

Signature transcription factors and cytokines designated to different cell types are shown. (encyclopedia.pub)

Alternative splicing of the primary transcript gives rise to the 2 mRNA and protein isoforms, hGR-alpha and hGR-beta. (medscape.com)

Bone morphogenic proteins (BMPs) promote osteogenesis, chondrogenesis and adipogenesis of mesenchymal progenitor cells [ 1 ]. (biomedcentral.com)

Other non-telomeric proteins, such as the DNA repair proteins Mre11 and Rad51, also play important roles at telomeres [ 7 , 8 ]. (biomedcentral.com)

NEMO consists of 10 exons, and most mutations cause deletions of exons 4-10, resulting in a truncated protein. (medscape.com)
Hypomorphic mutations may impair but not abolish NEMO protein function. (medscape.com)

Heterogeneous Ribonucleoprotein A1 (hnRNPA1) Interacts with the Nucleoprotein of the Influenza a Virus and Impedes Virus Replication. (cdc.gov)

To achieve this versatility PPARγ interacts with a range of additional molecules required for both transcriptional co-activation and structural changes that promote its dimerization for DNA binding. (nature.com)

Mammalian LH-2, a transcriptional regulatory protein involved in the control of cell differentiation in developing lymphoid and neural cell types. (embl.de)
Mammalian and avian cysteine-rich protein (CRP), a 192 amino-acid protein of unknown function. (embl.de)
In this work, we identified and characterized a Leishmania protein (LaTRF) homologous to both mammalian TRF1 and TRF2. (biomedcentral.com)
ClustalW and bl2seq sequence analysis showed that LaTRF shared sequence identity with the Trypanosoma brucei TRF (TbTRF) protein and had the same degree of sequence similarities with the dimerization (TRFH) and the canonical DNA-binding Myb-like domains of both mammalian TRFs. (biomedcentral.com)
Here we report that human hnRNPA1 physically interacts with the nucleoprotein (NP) of IAV in mammalian cells at different time points of the viral replication cycle. (cdc.gov)

Some LIM domains bind protein partners via tyrosine-containing motifs. (embl.de)
They display considerable versatility in binding modes, even between members of the same class (e.g. some bind DNA, others protein), suggesting that Znf motifs are stable scaffolds that have evolved specialised functions. (embl.de)
These motifs tend to be short and degenerate, so even when the DNA binding motif is known, one cannot generally predict where a given transcription factor may bind. (ucsc.edu)
proteins that bind specifically to single-stranded G-rich DNA, proteins that bind to double-stranded DNA and proteins that interact with telomeric factors. (biomedcentral.com)

The functional domains and subdomains are indicated beneath the linearized protein structures. (medscape.com)
Functional annotation clustering showed that they belong to cell cycle, organelle or nuclear lumen, protein transport, and DNA binding and repair clusters. (molvis.org)

Human Similarity Proteins of target is determined by comparing the sequence similarity of all human proteins with the target based on BLAST. (idrblab.net)

It stimulates the apical ectodermal ridge (AER), the ectoderm at the tip of the developing limb bud, to secrete several different fibroblast growth factors (FGF), especially FGF-2, FGF-4, and FGF-8. (medscape.com)

2000). "The leucine zipper of NRL interacts with the CRX homeodomain. (en-academic.com)
We are using zebrafish and mouse models to study the functions of factors such as Pbx homeodomain transcription factors and how they control muscle fiber-type development. (seattlechildrens.org)
Our group has shown that Pbx and Meis homeodomain transcription factors are critical regulators of heart development in zebrafish. (seattlechildrens.org)

ACLY could stabilize CTNNB1 (beta-catenin 1) protein by interacting, and the complex might promote CTNNB1 translocation through cytoplasm to nucleus, subsequently promote the CTNNB1 transcriptional activity and migration and invasion abilities of colon cancer cells. (biomedcentral.com)
The high expressed CBY1 in non-BCSC interacts with 14-3-3 and β-catenin to form a ternary complex, which leads a translocation of the ternary complex into cytoplasm from nucleus and degradation of β-catenin in phosphorylation-dependent pattern. (nature.com)

While some signals are mitogenic and proosteogenic, others function to inhibit osteogenesis and increase bone resorption, and it appears that a well-controlled, delicate balance of inflammatory factors is necessary for proper fracture repair [ 3 - 6 ]. (hindawi.com)
Matrix metalloproteinases (MMPs) are crucial factors in tumor progression, inflammatory/immune responses and tissue development/regeneration. (elsevierpure.com)

This protein is predicted to localize to the nucleus and is known to interact with the ATXN1 and ATF7IP proteins shown in the image below. (wikipedia.org)
We observed that, as skeletal muscle progressed from perinatal to postnatal and adult developmental stages, MSY3 protein became gradually dephosphorylated and accumulated in the nucleus. (biomedcentral.com)
In the nucleus, SLTM has a punctate distribution and it does not co-localize with SR (serine/arginine) proteins. (bris.ac.uk)

These data demonstrate that RanBPM interacts with steroid receptors to selectively modify their activity. (nih.gov)

High-risk types (e.g., types 16 and 18) can cause low-grade cervical cell abnormalities, high-grade cervical cell abnormalities that are precursors to cancer, and cancers ( 5 - 7 ). (cdc.gov)

In 2000, the International Incontinentia Pigmenti Consortium reported that incontinentia pigmenti is caused by a genomic rearrangement of the gene for NEMO, or nuclear factor kappa B essential modulator (IKBKG-IKK gamma). (medscape.com)
This information is based on mapping of SMART genomic protein database to KEGG orthologous groups. (embl-heidelberg.de)

The trihelix transcription factor (TF) family, as one of the earliest discovered TF families in plants, plays an essential part in responses to different abiotic stresses, and it has potential functions in improving the salt-tolerance capability of O. fragrans . (biomedcentral.com)

Global gene deletion studies in mice and humans have established the pivotal role of runt related transcription factor-2 (Runx2) in both intramembranous and endochondral ossification processes during skeletogenesis. (morulaivf.com)
MW) chemicals interact with host cells and molecules and In our daily life, we are confronted with a plethora of natural influence biologic processes such as signal transduction. (cdc.gov)

QRICH1, also known as Glutamine-rich protein 1, is a protein that in humans is encoded by the QRICH1 gene. (wikipedia.org)
Neural retina-specific leucine zipper protein is a protein that in humans is encoded by the NRL gene . (en-academic.com)

Western blot and indirect immunofluorescence combined with fluorescence in situ hybridization showed that LaTRF, similarly to hTRF2, is a nuclear protein that also associates with parasite telomeres. (biomedcentral.com)

Anatomy17

Organisms8

Chemicals and Drugs136

Analytical, Diagnostic and Therapeutic Techniques and Equipment23

Phenomena and Processes71

Disciplines and Occupations1

Information Science4

Genes10

Chromatin7

Bone morphogenic protein1

Signaling pathway2

Binds2

Receptor8

Subfamily1

Transcriptional repressor1

Metabolism2

Amino acids4

Highly conserved3

Cell Cycle Pr1

Histone2

Apoptosis5

Regulates1

Extracellular3

Variety of proteins2

Yeast3

Zinc5

Chromosome4

BHLH1

Recombinant4

Interaction4

19991

Expression18

Inhibitory4

Interactions7

Polymerase2

Kinases2

Elongation1

Regulator3

Cellular1

Kinase1

Cytokines1

MRNA and protein1

Mesenchymal1

Play important roles1

Mutations2

Ribonucleoprotein1

PPAR1

Mammalian5

Bind4

Functional2

Sequence similarity1

Secrete1

Homeodomain3

Cytoplasm2

Inflammatory2

Nucleus3

Receptors1

Cancers1

Genomic2

Family1

Processes2

Humans2

Nuclear protein1