• Safety and efficacy of a self-expanding versus a balloon-expandable bioprosthesis for transcatheter aortic valve replacement in patients with symptomatic severe aortic stenosis: a randomised non-inferiority trial. (ox.ac.uk)
  • BACKGROUND: Transcatheter aortic valve replacement (TAVR) is the preferred treatment option for older patients with symptomatic severe aortic stenosis. (ox.ac.uk)
  • METHODS: In this randomised non-inferiority trial, patients (aged ≥75 years) undergoing transfemoral TAVR for treatment of symptomatic severe aortic stenosis, and who were deemed to be at increased surgical risk, were recruited at 20 tertiary heart valve centres in Germany, the Netherlands, Switzerland, and the UK. (ox.ac.uk)
  • AIMS : Transcatheter aortic valve implantation (TAVI), now a common procedure to treat high-risk patients with severe aortic stenosis, has rapidly been expanding into younger and lower-risk populations, creating a need to better understand long-term outcome after TAVI. (lu.se)
  • Transcatheter aortic valve replacement (TAVR) has revolutionized the treatment of aortic stenosis and is the treatment of choice for patients at prohibitive and high surgical risk. (ahajournals.org)
  • NEW ORLEANS - Transcatheter aortic valve replacement (TAVR) with a self-expanding bioprosthesis ( CoreValve , Evolut R, or Evolut PRO , Medtronic) was noninferior to surgical aortic valve replacement in an interim Bayesian analysis of the primary endpoint - death from any cause or disabling stroke at 24 months - in a new trial involving patients with severe aortic stenosis at low surgical risk. (medscape.com)
  • The only definitive treatment for aortic stenosis in adults is aortic valve replacement, performed surgically or percutaneously. (medscape.com)
  • The development of symptoms due to aortic stenosis provides a clear indication for replacement. (medscape.com)
  • The Leadership Council of the American College of Cardiology (ACC) recommends considering percutaneous coronary intervention (PCI) in all patients with significant proximal coronary stenosis in major coronary arteries before transcatheter aortic valve replacement (TAVR), even though the indication is not covered in current guidelines. (medscape.com)
  • Medical treatment (such as diuretic therapy) in aortic stenosis may provide temporary symptom relief but is generally not effective long term. (medscape.com)
  • In truly asymptomatic patients with severe aortic stenosis, the issue of valve replacement is less clear. (medscape.com)
  • Prehospital and emergency department management is focused on acute exacerbations of the symptoms of aortic stenosis. (medscape.com)
  • A patient presenting with uncontrolled heart failure should be treated supportively with oxygen, cardiac and oximetry monitoring, intravenous access, loop diuretics, nitrates (remembering the potential nitrate sensitivity of patients with aortic stenosis), morphine (as needed and tolerated), and noninvasive or invasive ventilatory support (as indicated). (medscape.com)
  • Patients with severe heart failure due to aortic stenosis that is resistant to medical management should be considered for urgent surgery. (medscape.com)
  • However, nitroglycerin-induced syncope occurs more often in patients with aortic stenosis than in those without aortic stenosis. (medscape.com)
  • Syncope in the face of aortic stenosis should be assessed and treated as in any patient presenting with a syncopal episode. (medscape.com)
  • Atrial fibrillation in the setting of aortic stenosis is considered a medical emergency, and sinus rhythm should be restored urgently in patients who are hemodynamically unstable. (medscape.com)
  • The high rate of restenosis and the absence of a mortality benefit preclude its use as a definitive treatment method in adults with severe aortic stenosis. (medscape.com)
  • In children, adolescents, and young adults with congenital aortic stenosis, percutaneous balloon valvuloplasty carries a mortality risk of 1% and may be an alternative to surgical valvotomy. (medscape.com)
  • Although exercise restriction is sometimes recommended to avoid the risk of sudden unexpected death for some patients with congenital aortic stenosis, a recent study by Brown et al suggests that sudden unexpected death is extremely rare following balloon valvuloplasty, and the study found no beneficial effect for exercise restriction after the procedure is performed. (medscape.com)
  • Conclusion: We identified malondialdehyde, a marker of oxidative stress, as the most promising predictor of adverse outcomes during the 30-day and 1-year follow-up in high-risk patients with symptomatic, severe aortic stenosis treated with TAVI. (muni.cz)
  • One of the most important new treatment options is the percutaneous treatment for aortic valve stenosis (transcatheter aortic valve implantation), since aortic valve disease is a rather common problem in elderly patients, with many of them at high risk for surgery. (bmj.com)
  • Foremost in the development of percutaneous treatment options for aortic valve stenosis, transcatheter aortic valve implantation (TAVI) has improved the treatment options for elderly patients with aortic valve stenosis. (bmj.com)
  • Transcatheter Aortic Valve Replacement Versus Surgical Aortic Valve Replacement: How Would You Manage This Patient With Severe Aortic Stenosis? (acpjournals.org)
  • Aortic stenosis (AS) is common, especially among the elderly. (acpjournals.org)
  • The evolving epidemiology of valvular aortic stenosis. (acpjournals.org)
  • 4. Gaasch W. Natural history, epidemiology, and prognosis of aortic stenosis. (acpjournals.org)
  • Patients with mitral stenosis due to rheumatic fever may also have lesions of the aortic or tricuspid valve or both. (msdmanuals.com)
  • Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Severe, Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement (SURTAVI). (stanford.edu)
  • The purpose of the study is to investigate the safety and efficacy of transcatheter aortic valve implantation (TAVI) in patients with severe, symptomatic Aortic Stenosis (AS) at intermediate surgical risk by randomizing patients to either Surgical Aortic Valve Replacement (SAVR) or TAVI with the Medtronic CoreValve® System. (stanford.edu)
  • Single Arm: The purpose of this trial is to evaluate the safety and effectiveness of transcatheter aortic valve implementation (TAVI) in patients with severe symptomatic Aortic Stenosis (AS) at intermediate surgical risk with TAVI. (stanford.edu)
  • TAVI is feasible and shows comparable results to surgery in terms of early, 1-year mortality, as well as cerebrovascular events in patients with severe aortic stenosis and intermediate-low operative risk. (viamedica.pl)
  • Transcatheter aortic valve replacement has been an alternative to invasive treatment for symptomatic severe aortic stenosis in high risk patients. (rbccv.org.br)
  • Symptomatic patients with severe aortic stenosis have limited functionality and survival. (rbccv.org.br)
  • After the advent of transcatheter aortic valve replacement (TAVR) in 2002, symptomatic patients with severe aortic stenosis and high risk have an alternative intervention option, with survival and functional improvement. (rbccv.org.br)
  • The patient selection protocol started with individuals with severe aortic stenosis or dysfunctional biologic aortic valve being evaluated by a multidisciplinary team (formed by cardiologists, cardiac surgeons and nurses). (rbccv.org.br)
  • LVAD patients with bioprosthetic aortic valve are more prone to leaflet fusion resulting in valvular stenosis and regurgitation. (nebraska.edu)
  • In the right settings, TAVR in recovered LVAD patients with aortic stenosis as a bridge to LVAD deactivation is a viable option, especially for patients who fall in the high-risk group. (nebraska.edu)
  • Randomized comparison of stentless versus stented valves for aortic stenosis. (medtronic.com)
  • Aortic stenosis (AS or AoS) is the narrowing of the exit of the left ventricle of the heart (where the aorta begins), such that problems result. (wikipedia.org)
  • Aortic stenosis is typically followed using repeated ultrasound scans. (wikipedia.org)
  • Aortic stenosis is the most common valvular heart disease in the developed world. (wikipedia.org)
  • Aortic stenosis was first described by French physician Lazare Rivière in 1663. (wikipedia.org)
  • Symptoms related to aortic stenosis depend on the degree of stenosis. (wikipedia.org)
  • Most people with mild to moderate aortic stenosis do not have symptoms. (wikipedia.org)
  • Symptoms usually present in individuals with severe aortic stenosis, though they may also occur in those with mild to moderate aortic stenosis. (wikipedia.org)
  • The three main symptoms of aortic stenosis are loss of consciousness, anginal chest pain and shortness of breath with activity or other symptoms of heart failure such as shortness of breath while lying flat, episodes of shortness of breath at night, or swollen legs and feet. (wikipedia.org)
  • Exercise stress testing with or without imaging is strictly contraindicated in symptomatic patients with severe aortic stenosis. (wikipedia.org)
  • Syncope (fainting spells) from aortic valve stenosis is usually exertional. (wikipedia.org)
  • Transfemoral transcatheter aortic valve replacement is an effective treatment for severe aortic stenosis with a high rate of procedural success with the current devices. (bvsalud.org)
  • Aim of this study was to investigate the clinical outcomes of octuagenarians patients with severe aortic stenosis and intermediate-high risk treated either by means RDSV or TAVR in a multicenter evaluation. (ismics.org)
  • Among 397 consecutive patients with severe aortic stenosis and intermediate-high risk profile (STS-PROM 4-10% and Logistic Euroscore I 10-20%), a propensity-score analysis was performed based on the therapeutical strategy: RDSV (Group 1,G1, n=112) and TAVR (Group 2,G2, n=112). (ismics.org)
  • 0.001 0.81 TAVR was noninferior with respect to echocardiographic indexes of valve stenosis, functional status & quality of life Conclusion: In patients with severe aortic stenosis who are at increased surgical risk, TAVR with a self-expanding transcatheter aortic-valve bioprosthesis was associated with a significantly higher rate of survival at 1 year than surgical aortic-valve replacement. (visualmed.org)
  • Transcatheter aortic valve implantation (TAVI) is an alternative treatment for severe aortic valve stenosis (AS) in patients with prohibitive risk for surgical aortic valve replacement (SAVR). (opencardiovascularmedicinejournal.com)
  • The safety and effectiveness of the fully repositionable LOTUS valve system as compared with the balloon-expandable Edwards SAPIEN 3 prosthesis for the treatment of aortic stenosis has not been evaluated to date. (123dok.net)
  • ranscatheter aortic valve implantation (TAVI) has gained wide acceptance for the treatment of severe aortic stenosis among patients deemed to be at increased risk for surgical aortic valve replacement. (123dok.net)
  • Aortic valve stenosis occurs if the valve narrows and cannot open all the way, partially blocking the flow of blood out of the heart. (inbit.gr)
  • The objective of this analysis is to evaluate the safety, effectiveness, and cost-effectiveness of transcatheter aortic valve implantation (TAVI) for treatment of aortic valve stenosis (AVS) in symptomatic older adults. (inbit.gr)
  • Aortic valvular stenosis, or narrowing of the valve orifice, is a progressive disease that generally affects patients over the age of 65 years in Western countries and is usually caused by degenerative calcification. (inbit.gr)
  • Aortic stenosis causes increasing resistance against the ejection of blood from the left ventricle towards the aorta. (inbit.gr)
  • WASHINGTON, DC - (Updated with commentary) The SURTAVI trial hit its noninferiority end point, making it the second prospective randomized trial to show transcatheter aortic- valve replacement (TAVR) is comparable to surgery in severe aortic-stenosis patients deemed intermediate risk [ 1 ] . (medscape.com)
  • OBJECTIVES: To investigate the effect of TAVR technique on in-hospital and 30-day outcomes in patients with aortic stenosis (AS) and reduced ejection fraction (EF). (omeka.net)
  • Over the past two decades, transcatheter aortic valve implantation (TAVI) has been established as a viable alternative treatment to deal with severe aortic stenosis in patients at risk of open-heart surgery. (frontiersin.org)
  • The FDA recommends that healthcare providers be aware of the risk of SVD with Trifecta valves, discuss risk with patients, and monitor patients who have undergone implantation with Trifecta valves.Because of the potential risk of early structural valve deterioration, the FDA has sent notice about Abbott's decision to stop selling and distributing Trifecta aortic surgical heart valves in the United States. (ctsnet.org)
  • How to treat severe symptomatic structural valve deterioration of aortic surgical bioprosthesis: Transcatheter valve-in-valve implantation or redo valve surgery? (elsevierpure.com)
  • Current options for older patients who often have severe comorbidities include either transcatheter valve-in-valve (TVIV) implantation or redo valve surgery. (elsevierpure.com)
  • Aims: Our purpose was to determine long-term outcome of high-risk patients who underwent transcatheter aortic valve implantation (TAVI) with first-generation CoreValve device defining valve durability according to the 2017 EAPCI/ESC/EACTS definitions. (unipi.it)
  • This report summarises some key sessions on transcatheter aortic valve implantation (TAVI), valve-in-valve (ViV) interventions and optimisation of such procedures. (hospitalhealthcare.com)
  • Recently, the use of transcatheter aortic valve implantation (TAVI) in inter-mediate-low risk patients has been evaluated in the PARTNER II randomized trial. (viamedica.pl)
  • How should I treat an unexpected deadlock at the time of transcatheter aortic valve prosthesis implantation? (pcronline.com)
  • In structural heart interventions, my research assessed novel approaches in transcatheter aortic valve implantation (TAVI) as high valve implantation and bioprosthetic valve modification during valve-in-valve TAVI. (wikidoc.org)
  • Three-year outcomes of balloon-expandable transcatheter aortic valve implantation accor ding to annular size. (wikidoc.org)
  • Predictors of procedural success in patients with degenerated surgical valves undergoing transcatheter aortic valve-in-valve implantation. (wikidoc.org)
  • Durability of bioprosthetic surgical aortic valves in patients who underwent transcatheter valve-in-valve implantation. (wikidoc.org)
  • Methods We analyzed data obtained from 55 patients in a clinical trial of TAVR and from two single-center registries that included 132 patients who were undergoing either TAVR or surgical aortic-valve bioprosthesis implantation. (hofstra.edu)
  • El Hajj M, Krajcer Z . The Role of Transcatheter Aortic Valve Implantation in Patients With Bicuspid Valves in 2023. (viictr.org)
  • Background: Coronary access after transcatheter aortic valve implantation (TAVI) with supra-annular self-expandable valves may be challenging or un-feasible. (bvsalud.org)
  • There is little data concerning coronary access following transcatheter aortic valve-in-valve implantation (ViV-TAVI) for degenerated surgical bioprosthesis. (bvsalud.org)
  • Prophylactic coronary stenting, higher implantation, narrower aortic sinus dimensions and commissural misalignment were associated with an increased challenge of coronary cannulation. (bvsalud.org)
  • METHODS: The Women's International Transcatheter Aortic Valve implantation (WIN-TAVI) is a prospective registry evaluating the safety and efficacy of TAVR in women. (bvsalud.org)
  • Methods and Results--All patients undergoing transcatheter aortic valve implantation with the Edwards SAPIEN 3 or the LOTUS valve system were included into the Swiss Transcatheter Aortic Valve Implantation Registry. (123dok.net)
  • Implantation of prosthetic cardiac valves to treat hemodynamically significant aortic or mitral valve disease has become increasingly common. (medscape.com)
  • His special clinical interests include complex surgical mitral and tricuspid valve repair, minimally invasive surgery, transcatheter heart valve implantation, and aortic surgery. (cci-cic.org)
  • Dr. Ye has been teaching and training physicians and surgeons in transcatheter heart valve implantation and mitral valve repair in many countries over the past 10 years. (cci-cic.org)
  • Transcatheter aortic valve implantation (TAVI) is a less invasive procedure, originally developed as an alternative for patients at high or prohibitive surgical risk. (inbit.gr)
  • Transcatheter aortic valve implantation (TAVI), also referred to as transcatheter aortic valve replacement (TAVR), is the deployment of a bioprosthesis in the aortic valve using a catheter. (inbit.gr)
  • Transcatheter Aortic Valve Insertion - TAVI - is a technique involving the implantation of an artificial valve into a narrowed aortic valve without the need to stop the heart. (inbit.gr)
  • Transcatheter aortic valve implantation (TAVI) has become an alternative to surgical aortic valve replacement (sAVR) for patients at high risk for surgery. (inbit.gr)
  • In this study, transapical transcatheter mitral valve-in-valve implantation (TAMVI) was compared with surgical redo mitral valve replacement (SRMVR) in terms of clinical outcomes. (frontiersin.org)
  • Transapical transcatheter mitral valve-in-valve implantation (TAMVI) is now regarded as a promising alternative treatment for patients with degenerated bioprosthesis or failed annuloplasty ( 3 ). (frontiersin.org)
  • Development of a Risk Score to Predict New Pacemaker Implantation After Transcatheter Aortic Valve Replacement. (ucsf.edu)
  • In forty-eight consecutive patients undergoing explants of transcatheter aortic valve replacement (TAVR) at a single center between 2011 and 2021, at a median of 2.3 years after TAVR, the most common indications for surgery were nonstructural valve dysfunction (patient-prosthesis mismatch or paravalvular leak) in 35 percent, structural valve deterioration in 29 percent, and mitral valve disease in 29 percent. (ctsnet.org)
  • The good news is Hoag was the first center in Orange County to offer a ground-breaking minimally-invasive procedure for individuals who need aortic valve replacement called Transcatheter Aortic Valve Replacement (TAVR) . (hoag.org)
  • As a result, the procedure has been endorsed for patients at increased risk for surgical complications, and the number of TAVR interventions performed in the United States has now surpassed the number of isolated surgical aortic valve replacements, the study authors note in the NEJM paper. (medscape.com)
  • But use of TAVR in patients at low surgical risk requires compelling evidence of safety and effectiveness given the low mortality and stroke incidence with aortic valve surgery in relatively young and healthy patients, they add. (medscape.com)
  • The goal of the trial was to assess the safety and efficacy of transcatheter aortic valve replacement (TAVR) with the self-expanding CoreValve compared with surgical AVR (SAVR) in intermediate-risk patients. (acc.org)
  • Surgical aortic valve replacement (SAVR) was the standard of care until transcatheter aortic valve replacement (TAVR) was shown to have lower mortality rates in patients at the highest surgical risk and was recommended for this group in the 2014 American Heart Association/American College of Cardiology (AHA/ACC) guidelines. (acpjournals.org)
  • Due to high surgical risk, we performed valve-in-valve Trans-Catheter Aortic Valve Replacement (TAVR) with an Evolut self-expanding valve, however, the patient had significant aortic regurgitation secondary to deployment above the bioprosthetic valve ring. (nebraska.edu)
  • Background A finding of reduced aortic-valve leaflet motion was noted on computed tomography (CT) in a patient who had a stroke after transcatheter aortic-valve replacement (TAVR) during an ongoing clinical trial. (hofstra.edu)
  • Once it has become severe, treatment primarily involves valve replacement surgery, with transcatheter aortic valve replacement (TAVR) being an option in some who are at high risk from surgery. (wikipedia.org)
  • OBJECTIVES: To describe the incidence, predictors, and clinical impact of permanent pacemaker insertion (PPI) following transcatheter aortic valve replacement (TAVR) in women. (bvsalud.org)
  • Stroke remains a devastating complication of transcatheter aortic valve replacement (TAVR), with the incidence of clinically apparent stroke seemingly fixed at around 3% despite TAVR's significant evolution during the past decade. (pcronline.com)
  • The present review summarises the clinicopathological rationale for the development of CEPDs, the evidence behind these devices to date and the emerging recognition of cerebral embolisation in many non-TAVR transcatheter procedures. (pcronline.com)
  • Given the uniqueness of each of the various CEPDs under development, specific trials tailored to their designs will need to be undertaken to broaden the CEPD field, in addition to evaluating the role of CEPD in non-TAVR transcatheter heart interventions. (pcronline.com)
  • The use of transcatheter aortic valve replacement (TAVR) has been validated in patients at extremely high-risk or contraindicated to conventional cardiac surgery and more recently there has been a trend to extend TAVR also in patients with intermediate risk profile. (ismics.org)
  • Echocardiographic studies showed that the mean aortic-valve gradient was significantly lower (7.8% vs 11.8% at 2 years) and the effective AV orifice area significantly larger (2.2 cm 2 vs 1.7 cm 2 at 2 years) in the TAVR group than in the surgery group at all time points after the procedure. (medscape.com)
  • OBJECTIVE: The objective of this study was to analyze the available literature on using transcatheter aortic valve replacement (TAVR) for native aortic regurgitation (AR). (omeka.net)
  • OBJECTIVES: This study reports on the clinical effects of complete vs incompletely revascularized coronary artery disease on transcatheter aortic valve replacement (TAVR). (omeka.net)
  • OBJECTIVES: Data on next-day discharge (NDD) after transcatheter aortic valve replacement (TAVR) are limited. (omeka.net)
  • OBJECTIVES: The aim of this study was to determine the prevalence of peripheral artery disease (PAD) and its association with in-hospital outcomes after endovascular transcatheter aortic valve replacement (EV-TAVR). (omeka.net)
  • logistic EuroSCORE 21.0%) allocated to TAVI transfemoral and transapical using the Edwards-Sapien valve (n = 29), or SAVR with the Edwards Perimount bioprosthesis (n = 13). (muni.cz)
  • 1 Dr. Parma explained this is likely due to increasing comorbidities in patients, resulting in contraindications to anticoagulants, and further predicts that, in the majority of countries, the number of TAVI procedures will soon exceed those of surgical aortic valve replacement (SAVR). (hospitalhealthcare.com)
  • Multivariate analysis determined that aortic regurgitation (AR) was an independent predictor of mortality (OR = 3.623, 95% CI: 1.267-10.358, p = 0.016). (viamedica.pl)
  • Conclusions--The repositionable LOTUS valve system and the balloon-expandable Edwards SAPIEN 3 prosthesis appeared comparable in regard to the Valve Academic Research Consortium-2 early safety outcome, and the rates of more than mild aortic regurgitation were exceedingly low for both devices. (123dok.net)
  • Conversely, surgery was associated with less life-threatening or major bleeding (9.3% vs 12.2%) and lower rates of residual aortic regurgitation . (medscape.com)
  • Safety and efficacy of transcatheter aortic valve replacement for native aortic valve regurgitation: A systematic review and meta-analysis. (omeka.net)
  • The trileaflet valve is made of six individual pieces of porcine pericardium, with three pieces used to make a skirt at the inflow section of the valve thus preventing aortic regurgitation and three leaflet elements that are constructed with long commissures to distribute the aortic pressure load to the valve leaflets and the commissural posts. (wikidoc.org)
  • in the second generation they are made of bovine (cow) pericardium with improvements made in the frame suture and an increase in the skirt length to decrease the risk of aortic regurgitation . (wikidoc.org)
  • Two-year outcomes after transcatheter aortic valve-in-valve replacement in degenerat ed surgical valves. (wikidoc.org)
  • Long-term outcomes of transcatheter valve-in-valve replacement for failed aortic bioprosthesis: A meta-analysis. (wikidoc.org)
  • Outcomes among patients with heart failure with reduced ejection fraction undergoing transcatheter aortic valve replacement: Minimally invasive strategy versus conventional strategy. (omeka.net)
  • Short-term and long-term outcomes of patients undergoing urgent transcatheter aortic valve replacement under a minimalist strategy. (omeka.net)
  • Association of peripheral artery disease with in-hospital outcomes after endovascular transcatheter aortic valve replacement. (omeka.net)
  • Outcomes of transcatheter aortic valve replacement in end stage liver and renal disease. (ucsf.edu)
  • Repeat Pulmonary Valve Replacement: Similar Intermediate-Term Outcomes With Surgical and Transcatheter Procedures. (ucsf.edu)
  • Comparison of Clinical and Echocardiographic Outcomes After Surgical Redo Mitral Valve Replacement and Transcatheter Mitral Valve-in-Valve Therapy. (ucsf.edu)
  • Because of the potential risk of early structural valve deterioration, the FDA has sent notice about Abbott's decision to stop selling and distributing Trifecta aortic surgical heart valves in the United States. (ctsnet.org)
  • Three of these options include: homograft aortic valves (from a human donor), mechanical aortic valve replacement, and stentless aortic valve replacement. (hoag.org)
  • Indications: INSPIRIS RESILIA Aortic Valve - For use in replacement of native or prosthetic aortic heart valves. (edwards.com)
  • KONECT RESILIA Aortic Valved Conduit - For use in replacement of native or prosthetic aortic heart valves and the associated repair or replacement of a damaged or diseased ascending aorta. (edwards.com)
  • This issue becomes especially important when we try to compare the degeneration rate of surgically inserted and transcatheter bioprosthetic valves. (tau.ac.il)
  • The Freestyle™ bioprosthesis is for the replacement of malfunctioning native or prosthetic aortic valves with the option of aortic root replacement. (medtronic.com)
  • The Freestyle™ valve is hemodynamically superior to stented 3 and mechanical 4 valves in the aortic position because it's stentless and has no sewing ring. (medtronic.com)
  • Exercise hemodynamics of aortic prostheses: Comparison between stentless bioprostheses and mechanical valves. (medtronic.com)
  • Possible Subclinical Leaflet Thrombosis in Bioprosthetic Aortic Valves" by R. R. Makkar, G. Fontana et al. (hofstra.edu)
  • Pressure fixation of valves can compromise the function and durability of the bioprosthesis. (medtronic.com)
  • 1,2,3 The Physiologic Fixation process, used in Medtronic's third generation tissue valves, was developed to address the problem of structural valve deterioration caused by mechanical stress and is designed to maintain native collagen structure and porcine aortic root and leaflet geometry. (medtronic.com)
  • In a retrospective cohort analysis of 4253 patients who underwent primary isolated aortic-valve replacement, 15-year survival and stroke rates were equivalent with bioprosthetic and mechanical valves. (medscape.com)
  • Dr. Ye is a pioneer in the development and clinical application of transcatheter heart valves for heart valve disease. (cci-cic.org)
  • The aortic valve is one of four valves in the heart. (inbit.gr)
  • There has been a recent explosion in the field of transcatheter aortic and pulmonary valve replacements, but the atrio-ventricular valves have lagged behind for various reasons with the tricuspid valve undoubtedly the least treated valve of the four. (icrjournal.com)
  • 2017 will be the first year where we see more TAVRs done in the US than isolated aortic valves. (medscape.com)
  • There has been a notable shift away from mechanical valves toward bioprosthesis valves, despite their finite longevity. (frontiersin.org)
  • However, in the last years, this therapy has been employed in this scenario with underreported results, as compared to surgical aortic valve replacement (SAVR). (viamedica.pl)
  • Abstract Background Surgical aortic valve replacement (SAVR) is the conventional treatment in patients at low or intermediate surgical risk. (inbit.gr)
  • During aortic valve replacement surgery, the damaged valve is removed and replaced with an artificial valve called a prosthetic valve. (hoag.org)
  • With advances in modern surgical techniques, cardiac surgeons now have multiple methods to replace the aortic valve using innovative new prosthetic options. (hoag.org)
  • There are currently 8 prosthetic transcatheter valve types which are available. (wikidoc.org)
  • Postalian A, Krajcer Z . Facilitating future access to the coronary arteries in patients who need transcatheter aortic valve replacement: A significant step in the right direction. (viictr.org)
  • Health Status After Transcatheter Aortic Valve Replacement in Patients at Extreme Surgical Risk: Results From the CoreValve U.S. Trial. (stanford.edu)
  • In people with angina, the 5-year mortality rate is 50% if the aortic valve is not replaced. (wikipedia.org)
  • In propensity-matched comparisons, actuarial 15-year mortality rates were 60.6% with the bioprosthetic aortic valve and 62.1% with the mechanical valve. (medscape.com)
  • However, in cases where a valve is badly damaged, aortic valve repair may not be an option. (hoag.org)
  • This revolutionary non-surgical option utilizes a catheter to replace the damaged aortic valve. (hoag.org)
  • Fifty-eight patients underwent transcatheter aortic valve replacement. (rbccv.org.br)
  • We retrospectively identified patients with degenerated mitral bioprosthesis or failed annuloplasty rings who underwent redo SRMVR or TAMVI at our medical center. (frontiersin.org)
  • Impact of Complications During Transfemoral Transcatheter Aortic Valve Replacement: How Can They Be Avoided and Managed? (ahajournals.org)
  • Impact of residual coronary atherosclerosis on transfemoral transcatheter aortic valve replacement. (omeka.net)
  • Feasibility and safety of adopting next-day discharge as first-line option after transfemoral transcatheter aortic valve replacement. (omeka.net)
  • Then the coronary arteries are implanted in the graft using aortic buttons. (hoag.org)
  • Segar MW, Krajcer Z . Sex-based differences in patients undergoing transseptal transcatheter mitral valve replacement: Closing the sex disparity gap. (viictr.org)
  • CT in transcatheter-delivered treatment of valvular heart disease. (150.254.179)
  • Repairing versus replacing the aortic valve is determined by a number of factors, such as the anatomy of the valve and the degree of its disease. (hoag.org)
  • It is also indicated whenever there is a combined dilation of the aortic root and annulus, as well as the ascending aorta. (hoag.org)
  • They claimed that can cover aortic annulus diameters from 21 to 27 mm. (wikidoc.org)
  • [5] The design of this portion of the frame with its radial strength prevents annular recoil, allowing the frame to partially conform to the non circular shape of the aortic annulus. (wikidoc.org)
  • Another less invasive procedure, balloon aortic valvuloplasty (BAV), may result in benefit, but for only a few months. (wikipedia.org)
  • The reoperation rate was 12.1% in the bioprosthetic valve group at 15 years and 6.9% in the mechanical valve group, while major bleeding occurred in 6.6% of bioprosthesis patients and in 13.0% of the mechanical-valve group. (medscape.com)
  • Mitral Bioprosthetic Valve Fracture: Bailout Procedure for Undersized Bioprosthesis During Mitral Valve-in-Valve Procedure With Paravalvular Leak Closure. (ucsf.edu)
  • The optimal management of aortic surgical bioprosthesis presenting with severe symptomatic structural valve deterioration is currently a matter of debate. (elsevierpure.com)
  • The aim of this review is to provide a framework for individualized optimal treatment strategies in patients with failed aortic surgical bioprosthesis. (elsevierpure.com)
  • Secondary endpoints were to compare the clinical and echocardiographic variation pre-and post- transcatheter aortic valve replacement, and the occurrence of complications throughout a 4-year follow-up period. (rbccv.org.br)
  • Transcatheter aortic valve replacement had positive clinical and hemodynamic results, when comparing pre-and post-procedure, and the hemodynamic profile of the prosthesis was sustained throughout follow-up. (rbccv.org.br)
  • Its goal is to improve the quality of research and clinical care for patients with deteriorated bioprostheses by providing objective and strict criteria that can be utilized in future clinical trials. (tau.ac.il)
  • Surgical explantation of transcatheter aortic bioprostheses: Results and clinical implications. (uchicago.edu)
  • Research Questions: What is the clinical effectiveness and safety of the Perceval S sutureless valve for patients requiring aortic valve replacement? (inbit.gr)
  • Transcatheter versus surgical aortic-valve replacement in high-risk patients. (acpjournals.org)
  • Transcatheter Versus Surgical Aortic Valve Replacement Episode Payments and Relationship to Case Volume. (uchicago.edu)
  • A comparative study of minimally invasive aortic valve replacement with sutureless biological versus mechanical prostheses. (150.254.179)
  • During a Porcine Root Replacement, the aortic root is replaced with a preserved pig aorta. (hoag.org)
  • The Hancock M.O. II aortic bioprosthesis (porcine). (medscape.com)
  • The full root, stentless design of the Freestyle™ porcine bioprosthesis - based on more than 30 years of Medtronic tissue valve design improvements - can be used for full root, modified subcoronary, and complete subcoronary configurations. (medtronic.com)
  • El Hajj M, Krajcer Z . A roadmap to arrhythmias after transcatheter pulmonary valve replacement in pediatric patients. (viictr.org)
  • Bioprostheses are prone to structural valve degeneration, resulting in limited long-term durability. (tau.ac.il)
  • A significant challenge when comparing the durability of different types of bioprostheses is the lack of a standardized terminology for the definition of a degenerated valve. (tau.ac.il)
  • however, unplanned aortic root replacement because of aortic root trauma during explantation was required in four patients, and root enlargement was required in four patients. (ctsnet.org)
  • Bentall with Bioprosthesis is a replacement of the aortic valve, root, and the entire ascending aorta, utilizing a graft. (hoag.org)
  • This can be a reasonable replacement for the same indications as a homograft, as well as for a replacement of a short segment of aorta (aortic root). (hoag.org)
  • 5. Arora S , Misenheimer JA , Ramaraj R . Transcatheter aortic valve replacement: comprehensive review and present status. (acpjournals.org)
  • This prospective cohort, nestled to a multicenter study (Registro Brasileiro de Implante de Bioprótese por Cateter), describes the experience of a public tertiary center in transcatheter aortic valve replacement. (rbccv.org.br)
  • Evolving trends in aortic valve replacement: A statewide experience. (uchicago.edu)
  • Aortic valve reintervention after transcatheter aortic valve replacement. (uchicago.edu)
  • For the first time, I tested the real-world feasibility of the novel transcatheter tricuspid repair/replacement interventions. (wikidoc.org)
  • Measured or predicted patient-prosthesis mismatch following aortic valve replacement. (wikidoc.org)
  • Krajcer Z . A Minimalist Transcatheter Aortic Valve Replacement Approach: Safety and Effectiveness in Real-World Practice. (viictr.org)
  • 1 Transcatheter tricuspid valve replacement (TTVR) offers a new solution to this dilemma and this article will focus on transcatheter approaches to tricuspid valve replacement. (icrjournal.com)
  • Despite the explosion in the field of transcatheter aortic valve implantations over the last 10 years, only a handful of transcatheter tricuspid valve-in-valve implants have been described to date. (icrjournal.com)
  • Reduced leaflet motion was detected among patients with multiple bioprosthesis types, including transcatheter and surgical bioprostheses. (hofstra.edu)
  • The Edwards SAPIEN 3 Transcatheter Heart Valve is comprised of a balloon-expandable, radiopaque, cobalt-chromium frame, trileaflet bovine pericardial tissue valve, and polyethylene terephthalate (PET) fabric skirt. (wikidoc.org)