Trachomatis momp localization chlamydia trachomatis. Medical search. Frequent questions

Certainly, the serovar-defining major outer membrane protein (MOMP) is a prime example of point mutation accumulation resulting in genetic variants, especially in the surface-exposed segments of this molecule. (medscape.com)

15. Detection of IgM antibodies to Chlamydia trachomatis, Chlamydia pneumoniae, and Chlamydia psittaci from Japanese infants and children with pneumonia. (nih.gov)
In contrast, nonaborting experimentally infected sheep developed mainly antibodies to surface antigens (MOMP, MIP, Pmp13G), all of which did not persist. (infektiologie.tirol)

Chlamydia trachomatis is a global cause of blinding trachoma and sexually transmitted infections (STIs). (cdc.gov)
Worldwide, C. trachomatis is the leading preventable cause of blindness and bacterial sexually transmitted infections (STIs). (cdc.gov)
The most specific antigen for the serodiagnosis of human C abortus infections was Pmp13G, which showed no cross-reactivity with other chlamydiae infecting humans. (infektiologie.tirol)

2. Recombinant protein CPSIT_0846 induces protective immunity against Chlamydia psittaci infection in BALB/c mice. (nih.gov)
3. Protective immunity induced by recombinant protein CPSIT_p8 of Chlamydia psittaci. (nih.gov)
5. A recombinant multi-epitope peptide vaccine based on MOMP and CPSIT_p6 protein protects against Chlamydia psittaci lung infection. (nih.gov)
[ 6 , 38 , 39 ] In another study, an isolate from rectal epithelia was found to be a recombinant of C. trachomatis serovar D and LGV resulting in a hypervirulent strain (L 2 C) causing severe hemorrhagic proctitis. (medscape.com)

16. The Chlamydia psittaci genome: a comparative analysis of intracellular pathogens. (nih.gov)
[ 35 ] There has also been strong bioinformatics evidence after whole-genome sequencing that chlamydiae have undergone a number of gene duplication events resulting in the creation of several families of proteins important for intracellular survival in cell culture and possibly in disease severity differences. (medscape.com)
The obligate intracellular bacterium Chlamydia abortus is the causative agent of enzootic abortion of ewes and poses a significant zoonotic risk for pregnant women. (infektiologie.tirol)
Enzootic abortion of ewes (EAE) due to infection with the obligate intracellular pathogen Chlamydia (C.) abortus is an important zoonosis leading to considerable economic loss to agriculture worldwide. (infektiologie.tirol)

20. Tandem genes of Chlamydia psittaci that encode proteins localized to the inclusion membrane. (nih.gov)
We used comparative genomics of the family Chlamydiaceae to select conserved housekeeping genes for C. trachomatis multilocus sequencing, characterizing 19 reference and 68 clinical isolates from 6 continental/subcontinental regions. (cdc.gov)

4. Chlamydia psittaci hypothetical inclusion membrane protein CPSIT_0842 evokes a pro-inflammatory response in monocytes via TLR2/TLR4 signaling pathways. (nih.gov)
6. Analysis of Polymorphic Membrane Protein Expression in Cultured Cells Identifies PmpA and PmpH of Chlamydia psittaci as Candidate Factors in Pathogenesis and Immunity to Infection. (nih.gov)
7. Cloning and characterization of a Chlamydia psittaci gene coding for a protein localized in the inclusion membrane of infected cells. (nih.gov)
9. Chlamydia psittaci inclusion membrane protein CPSIT_0842 induces macrophage apoptosis through MAPK/ERK-mediated autophagy. (nih.gov)
12. Immunization with Chlamydia psittaci plasmid-encoded protein CPSIT_p7 induces partial protective immunity against chlamydia lung infection in mice. (nih.gov)
Analysis of the subcellular localization of both proteins throughout the developmental cycle revealed CAB063 being the first C. abortus protein shown to be translocated to the host cell nucleus. (infektiologie.tirol)

1. Localization and characterization of two putative TMH family proteins in Chlamydia psittaci. (nih.gov)
17. Immunoreactivity of the 60 kDa cysteine-rich proteins of Chlamydia trachomatis, Chlamydia psittaci and Chlamydia pneumoniae expressed in Escherichia coli. (nih.gov)
19. Sequence analysis and lipid modification of the cysteine-rich envelope proteins of Chlamydia psittaci 6BC. (nih.gov)

Genetic variation allows Chlamydia trachomatis to exploit diverse niches within a host (tissue tropism) and to avoid, escape or resist host responses. (medscape.com)

18. Homologs of Escherichia coli recJ, gltX and of a putative 'early' gene of avian Chlamydia psittaci are located upstream of the 'late' omp2 locus of Chlamydia psittaci strain guinea pig inclusion conjunctivitis. (nih.gov)
Consequently, new Chlamydia genotypes arise within the population and the potential for strain selection with increased virulence is possible. (medscape.com)
A 30-kb region between ctl393 and ctl417 found in the E/SW2 strain (Swedish New Variant) exactly matched the sequence for C. trachomatis D/UW3/CX. (medscape.com)

Multilocus and SNP typing can now be used to detect diverse and emerging C. trachomatis strains for epidemiologic and evolutionary studies of trachoma and STI populations worldwide. (cdc.gov)

We have shown that aborting sheep exhibited a strong antibody response to surface (MOMP, MIP, Pmp13G) and virulence-associated (CPAF, TARP, SINC) antigens. (infektiologie.tirol)