• Thus, the cumulative effect of vitamin E, selenium, zinc, folic acid, and n-3 polyunsaturated fatty acids (PUFA) on sperm motility and membrane properties was investigated in healthy normospermic dogs. (mdpi.com)
  • Iron, copper, manganese, zinc (trace elements), lead, cadmium, and nickel (toxic metals) were chosen as representatives, whose levels in the environment represent a reliable index of environmental pollution [ 24 ]. (hindawi.com)
  • Minerals such as iron, copper, zinc and manganese are essential metals since they play an important role in biological systems, whereas lead and cadmium are nonessential metals as they are toxic, even in traces [ 25 ]. (hindawi.com)
  • Selenium is another mineral that may be just as important as Zinc for healthy cells and overall health support. (red23.co.uk)
  • Because supplementing with any type of Zinc can reduce your copper, an important micronutrient, we've added a very small amount of copper to our Zinc Plus Selenium. (red23.co.uk)
  • Your age, your diet, your current health status, your lifestyle, and even your zip code may be placing you at a greater risk for a zinc or selenium deficiency or both. (red23.co.uk)
  • Order Dr Mercola bioavailable and balanced Zinc Plus Selenium today for your peace of mind for healthy cells, a healthy immune response, your cognitive health, as well as a healthy metabolism, bones, and vision. (red23.co.uk)
  • and important mineral trace elements depleted in land grown foods like zinc, selenium, iron, and magnesium. (positivehealth.com)
  • Because trace elements such as selenium, zinc, manganese and copper protect the body from oxidative stress, one research group in Iran recently explored the hypothesis that oxidation status may contribute to cribbing. (horse-canada.com)
  • This salt delivers significant levels of magnesium, zinc and selenium, with trace levels of dozens of other elements. (naturalnews.com)
  • All three plants contained potentially useful amounts of copper, zinc, iron, and a number of other essential minerals and trace elements, but no detectable selenium. (cdc.gov)
  • Aucune différence significative en termes de concentration moyenne d'iode urinaire ou de taux sérique de facteur de croissance IGF-1 ou de zinc n'a été constatée entre les élèves qui présentaient un goitre et ceux qui n'en avaient pas. (who.int)
  • But as he points out, trace element deficiency was probably not the only factor contributing to these mass extinctions. (cosmosmagazine.com)
  • As continents stretch and compress, volcanoes erupt and die, oceans are born and squeezed dry, and the climate can swing wildly from hot and humid to icy cold - all of which, combined with selenium deficiency, can contribute to extinction events. (cosmosmagazine.com)
  • Many parts of the U.S. as well as Europe, Australia, Russia, New Zealand and China have low soil levels of selenium, increasing your risk for deficiency. (red23.co.uk)
  • Furthermore, due to the strong relationship between iodine and selenium in metabolic processes, selenium deficiency often compromises the desired positive impact of salt iodization efforts. (muni.cz)
  • Endemic selenium (Se) deficiency is a major worldwide nutritional challenge. (cabi.org)
  • Deficiency of the trace elements cobalt, iodine, selenium, and copper are major factors in the raising of healthy livestock. (country-wide.co.nz)
  • Deficiency tends to occur in growthy seasons when trace element levels in pasture are diluted, and less soil is ingested. (country-wide.co.nz)
  • Selenium deficiency is more prevalent in growthy summers for sheep. (country-wide.co.nz)
  • An increased risk of selenium deficiency can be alerted to by pasture analysis. (country-wide.co.nz)
  • For cattle, selenium deficiency reduces conception rate, calf survival and growth rates. (country-wide.co.nz)
  • Researchers still don't understand exactly what causes cribbing in horses, but they now suspect selenium deficiency might be one reason. (horse-canada.com)
  • Where can I find a Trace Mineral Deficiency Panel near me? (requestatest.com)
  • A research study at Lund University shows that there is an association between selenium deficiency and an increased risk of developing heart failure. (lu.se)
  • Since the 1960s, it has been known that chronic selenium deficiency leads to an aggressive type of heart failure, primarily affecting children and young people in areas with selenium-poor soil. (lu.se)
  • Already in 2019, our research group demonstrated that selenium deficiency is linked to a worsened prognosis in patients with established heart failure, says Martin Magnusson, cardiologist at Skåne University Hospital, adjunct professor at Lund University, and Clinical Fellow at the Wallenberg Center for Molecular Medicine. (lu.se)
  • In this current study, published in the journal Free Radical Biology and Medicine, the researchers observed that selenium deficiency is also associated with an increased risk of developing heart failure in individuals who do not have a known history of heart disease. (lu.se)
  • However, the researchers emphasize that they still do not know whether the selenium deficiency itself has this effect on the prognosis of heart failure or if it is the heart failure that affects selenium levels. (lu.se)
  • The review of trials of selenium supplementation for preterm babies found that it reduces sepsis (blood infection). (cochrane.org)
  • Higher than usual levels of selenium supplementation may be beneficial, but more research is needed as most of the evidence comes from a country where selenium levels were unusually low. (cochrane.org)
  • To assess the benefits and harms of selenium supplementation in preterm or very low birth weight (VLBW) infants. (cochrane.org)
  • Randomised controlled trials which compared selenium supplementation either parenterally or enterally with placebo or nothing from soon after birth in preterm or VLBW infants and which reported clinical outcomes were considered for the review. (cochrane.org)
  • Supplementation with selenium was not associated with improved survival, a reduction in neonatal chronic lung disease or retinopathy of prematurity. (cochrane.org)
  • Organic and inorganic selenium supplementation to lactating mothers increase the blood and milk Se concentrations and Se intake by breast-fed infants. (deepdyve.com)
  • The largest clinical trial ever conducted on the use of dietary supplements to prevent cancer was the selenium and vitamin E supplementation randomized trial (SELECT). (medscape.com)
  • Brazil nuts are commonly used as a form of selenium supplementation, but it isn't commonly known that the level of selenium in Brazil nuts is highly variable. (zrtlab.com)
  • Therefore, a considerable number of studies have looked for alternative methods for the simultaneous supplementation of selenium and iodine in foodstuff. (muni.cz)
  • Also, pregnant or lactating women may require higher levels of selenium, and people with certain health Conditions may also require higher or lower levels. (jakchang.com)
  • Meats produced from animals that ate grains or plants found in selenium-rich soil have higher levels of selenium. (medlineplus.gov)
  • Our results support an increased risk of pancreatic cancer associated with higher levels of cadmium, arsenic, and lead, as well as an inverse association with higher levels of selenium and nickel. (medicalnewstoday.com)
  • Higher levels of selenium intake in the range of 200-300 µg/day are believed to be effective in the prevention of certain types of cancer such as lung, colon and prostate [7] [8] . (zrtlab.com)
  • However, selenium toxicity is rare in the United States. (medlineplus.gov)
  • Selenium toxicity can result in hair loss, tremors, kidney failure, cardiac failure, neurological and gastrointestinal issues, respiratory distress and even death [6] [11] . (zrtlab.com)
  • Warning - selenium toxicity is possible if treatments are administered incorrectly. (country-wide.co.nz)
  • Interactions between heavy metals and selenium can significantly affect their biological toxicity, although little is known about the mechanism of this antagonism. (bvsalud.org)
  • The recommended daily intake of selenium varies depending on different sources and guidelines. (jakchang.com)
  • However, please note that Selenium levels can vary dep the geographic location, soil and so on. (jakchang.com)
  • It is important to note that selenium levels from food sources can vary depending on the geographic location, soil and agricultural practices, so it's important to consult with a healthcare professional for advice about selenium intake. (jakchang.com)
  • How much selenium is in the vegetables you eat depends on how much of the mineral was in the soil where the plants grew. (medlineplus.gov)
  • Whereas plants on land can access selenium by wriggling their roots down into the soil, plankton are completely reliant on ground-up material washed into the ocean. (cosmosmagazine.com)
  • Soil conditions in parts of South America are unique in that they are deficient in sulfur, a necessary element required for the formation of the amino acids methionine and cysteine [1] . (zrtlab.com)
  • Selenium content depends on the region in which the tree is grown, the pH of the soil, and can vary from nut to nut in a single batch or between trees [2] . (zrtlab.com)
  • Trace elements in animals, not in the soil, are the subject of this article although the two topics can be interrelated. (country-wide.co.nz)
  • There are several benefits of getting enough selenium from your diet or supplements. (jakchang.com)
  • It is always recommended to consult with a healthcare professional before taking any selenium supplements, especially if you are pregnant, breastfeeding, have any medical conditions, or are taking any medications. (jakchang.com)
  • Keshan disease caused many childhood deaths in China until the link to selenium was discovered and supplements were given. (medlineplus.gov)
  • Higher doses of selenium supplements may be able to reduce some complications for preterm babies, but more research is needed. (cochrane.org)
  • Because other foods, beverages, and supplements provide selenium on top of Brazil nuts, it is best to measure total daily selenium intake. (zrtlab.com)
  • However, when it comes to supplements, not all selenium supplements are the same. (red23.co.uk)
  • It is the full protein form of selenium compared with a single amino acid form like selenomethionine, which is more commonly found in selenium supplements and in multivitamins. (red23.co.uk)
  • Recall of dietary supplements has brought attention to selenium, a naturally occurring trace mineral element found in rocks and soils. (cdc.gov)
  • Although there were suggestions that selenium supplements may reduce the chance of developing prostate cancer, many studies refuted this and claimed that there was no actual benefit. (infirmiers.com)
  • Geologist Ross Large from the University of Tasmania was relying on the fact that the trace element selenium is often found near nickel and copper ore deposits. (cosmosmagazine.com)
  • Selenium is a trace mineral that can be found in certain foods. (jakchang.com)
  • Thus, the present paper is focused on the analysis of four species of mushrooms namely Lentinus cladopus, Lentinula edodes, Pleurotus djamor, and Pleurotus florida for their mineral contents and to discuss the results generated on essential and trace elements in edible mushrooms, along with the limits of toxic metals. (hindawi.com)
  • The use of olive cake in the diet of dairy cows improves the mineral elements of Provola cheese. (cabi.org)
  • Herein we report the fatty acid, amino acid and mineral and trace element content of three leafy plant foods collected in July 2002 in the villages of Droum and Zongon Mallam in the Republic of Niger: cecego (Sesbania pachycarpa), godilo/gudai (Crataeva religiosa), and cabbage leaf (Brassica oleracea var. (cdc.gov)
  • Liver selenium levels of less than 250nmol/l are deficient, and greater than 450nmol/l adequate. (country-wide.co.nz)
  • Cattle are deficient when selenium concentration in the blood is less than 130nmol/l. (country-wide.co.nz)
  • These results suggest that decreased DNA methyltransferase activity may protect selenium deficient animals against colon cancer susceptibility. (usda.gov)
  • Dosages for selenium, as well as other nutrients, are provided in the Dietary Reference Intakes (DRIs) developed by the Food and Nutrition Board at the National Academies of Sciences, Engineering, and Medicine. (medlineplus.gov)
  • Selenium is an essential trace element gained from nutrients. (cochrane.org)
  • Trace minerals are vital nutrients that our body needs in very small (or "trace") amounts. (traceminerals.com)
  • The humble mushroom may not be the first thing you think of when it comes to health foods, but this delicious fungus has many healthful nutrients , including selenium. (saveourbones.com)
  • 6. 'Food components' refer to the nutrients or non-nutrients additionally added to the product or the elements of raw materials that are used for manufacturingprocessing or cooking of food or food additives which are not additionally added to the product. (who.int)
  • Selenium and sulfur are chemically very similar, so plants take up selenium in place of sulfur, forming the amino acids selenomethionine and selenocysteine. (zrtlab.com)
  • In a New Zealand study, 59 adults were separated into three groups, receiving either Brazil nuts (2 nuts a day or an estimated 100 µg selenium/day), selenomethionine tablets (100 µg selenium/day), or placebo tablets (no selenium) for 3 months [12] . (zrtlab.com)
  • Dairy: Milk and cheese also contains selenium. (jakchang.com)
  • or long-acting injectable, for example Smart Shot, which contains selenium and lasts six or seven months which requires 0.5ml at docking (lasting six or seven weeks) followed by 1ml at weaning lasting another eight months. (country-wide.co.nz)
  • One of the main functions of selenium in the body is as a component of glutathione peroxidases (GPx), which are enzymes that neutralize hydrogen peroxide and organic hydroperoxides produced during metabolism. (jakchang.com)
  • Selenium is an essential trace element and component of a number of selenoproteins including glutathione peroxidase, which has a role in protecting against oxidative damage. (cochrane.org)
  • Selenium reduced oxidative stress by increasing the activity of glutathione (GSH), superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX) and malondialdehyde (MDA). (bvsalud.org)
  • Given that nails and toenails in particular are believed to be more reliable indicators of trace element levels compared with dietary assessment because of their ability to store intake/exposure from other sources over the long term, the researchers examined the study participants' toenails for 12 trace element levels. (medicalnewstoday.com)
  • The Institute of Medicine's Food and Nutrition Board set a recommended dietary allowance of 55 µg selenium/day for adults with a tolerable upper intake level of 400 µg selenium/day [6] . (zrtlab.com)
  • Metabonomic analysis of the haemolymph reveals the dual effects of dietary selenium supplementations on growth of silkworm Bombyx mori . (cabi.org)
  • So just play it safe and encourage your human to eat iodized salt and seafood as the major dietary sources of iodine or plant foods containing selenium. (cdc.gov)
  • Studies were conducted to determine whether a DNA methyltransferase inhibitor would alter the effect of dietary selenium on the formation of aberrant crypts, a preneoplastic lesion for colon cancer. (usda.gov)
  • however, when animals were injected with a DNA methyltransferase inhibitor, there was a significant reduction in aberrant crypt formation and dietary selenium did not affect aberrant crypt formation. (usda.gov)
  • This study investigated whether the DNA methyltransferase inhibitor, 5-aza-2'-deoxycytidine (aza-dC) would alter the effect of dietary selenium (Se) on the formation of aberrant crypts. (usda.gov)
  • This experiment was conducted to determine the influences of adding organic selenium (Se) on growth properties, Se absorption and utilization, immunity and antioxidant activity in diets of Duroc weaning piglets. (scirp.org)
  • Other trace elements usually were present in concentrations less than 20 mg/L. Volatile organic compounds were detected in water from 11 of 20 wells sampled. (usgs.gov)
  • The selenium enrichment procedure was optimized to produce the selenium-enriched Tibetan kefir grains (SeTKGs) with high microbial activity and organic selenium percentage (OSP). (cabi.org)
  • Selenium is also known for its antioxidant properties and pro rad to neut cells from oxidative stress. (jakchang.com)
  • These enzymes are important for preventing selenium oxidatives damage to cell Also a component of a different family of enzymes called thioredoxin reductases (TrxRs), which also help protect cells against oxidative stress. (jakchang.com)
  • Antioxidant protection: Selenium acts as an antioxidant by neutralizing harmful free radicals and protecting cells from oxidative stress. (jakchang.com)
  • In experimental animals low selenium concentrations appear to increase susceptibility to oxidative lung disease. (cochrane.org)
  • Some researchers also suspect a link between trace element deficiencies resulting in oxidative stress and the stereotypy. (horse-canada.com)
  • Based on these data, the researchers concluded "that alterations in serum selenium, an important component of the antioxidant system, may play a role in the pathophysiology of cribbing behaviour in horses, adding further evidence to the theory that cribbing may be related to increased oxidative stress and alterations in essential trace elements. (horse-canada.com)
  • Several observational studies have found an association between higher selenium levels and a lower risk of certain types of cancer, including prostate cancer and breast cancer. (jakchang.com)
  • Thyroid function: Selenium is essential for the proper metabolism of thyroid hormones, which regulates metabolism and energy levels. (jakchang.com)
  • Cancer prevention: Some research suggests that higher selenium levels may be associated with a lower risk of certain types of cancer, such as prostate cancer and breast cancer. (jakchang.com)
  • The palaeontologist immediately noticed something intriguing: selenium levels plummeted just ahead of the three mysterious mass extinctions. (cosmosmagazine.com)
  • But in periods where landmasses are drifting apart - such as 200 million years ago, when the vast supercontinent Pangaea was breaking up - selenium levels can collapse. (cosmosmagazine.com)
  • Towards the end of the Triassic period, 205 million years ago, selenium levels were around 60 parts per million in ocean sediments. (cosmosmagazine.com)
  • Since information on the endogenous Se levels of infant formulae is largely lacking, therefore there is still need for stricter quality control of the selenium content in infant formulae. (deepdyve.com)
  • 1. The levels of PCBs, organochlorine pesticides, and trace elements found in land crabs are much lower than levels reported in the scientific literature as causing harmful health effects. (cdc.gov)
  • According to a study published online in Gut , high levels of the trace elements nickel and selenium in the body may lower the risk of developing the most common type of pancreatic cancer , whilst high levels of arsenic, lead, and cadmium could increase the risk of developing the disease. (medicalnewstoday.com)
  • The findings revealed levels of certain trace elements were substantially higher or lower amongst cancer patients compared to those in the control group. (medicalnewstoday.com)
  • Furthermore, those patients with the highest levels of nickel and selenium in their toenails were between 33% and 95% less likely to have the disease than those with the lowest levels. (medicalnewstoday.com)
  • Cadmium is a known carcinogen and has been linked to an increased risk of lung, kidney, and prostate cancers , whilst high levels of selenium have been linked to offering protection against certain cancers. (medicalnewstoday.com)
  • Brazil nuts, therefore, increase plasma selenium levels and antioxidant production in this human population. (zrtlab.com)
  • If you are planning on supplementing with Brazil nuts, it is highly recommended that you test your urine selenium levels to determine if safe levels of selenium are being consumed. (zrtlab.com)
  • selenium decreases levels of eltrombopag by inhibition of GI absorption. (medscape.com)
  • The most important finding in this study was that blood serum selenium concentration was significantly lower in cribbing horses than in controls, with the lowest levels measured while horses were actually cribbing. (horse-canada.com)
  • Excessive levels of one or more trace minerals can cause symptoms such as skin rash, hair loss, liver or kidney failure, seizures, and numbness or pain in the hands or feet. (requestatest.com)
  • The risk is twice as high for individuals with low selenium levels. (lu.se)
  • The study shows an association between low selenium levels and an increased risk of developing heart failure over a follow-up period of 15 years. (lu.se)
  • The risk was twice as high in the 20 percent with the lowest selenium levels, says Amra Jujic, postdoctoral researcher at Lund University and the first author of the study. (lu.se)
  • Brewer's yeast, wheat germ, and enriched breads are also good sources of selenium. (medlineplus.gov)
  • Studies show that a specific form of standardized selenium-enriched yeast is a more effective form. (red23.co.uk)
  • Brazil nuts are well known for their high concentration of selenium. (zrtlab.com)
  • In a single study, Brazil nut selenium concentration ranged from 0.03 to 512 µg/g, a substantial difference [4] . (zrtlab.com)
  • At the highest concentration, a single serving of Brazil nuts (around 6 whole nuts) could result in a selenium intake of 14515 µg, much higher than the recommended daily amount (RDA) of 55 µg [5] . (zrtlab.com)
  • Electrical signals resulting from the detection of the ions are processed into digital information that is used to indicate the intensity of the ions and subsequently the concentration of the element. (cdc.gov)
  • La concentration d'iode urinaire moyenne des enfants qui présentaient un goitre et des enfants sains était respectivement de 17,4 µg/dl et 15,3 µg/dl, suggérant un apport en iode adéquat. (who.int)
  • Un questionnaire standard a été utilisé et la concentration en plomb a été mesurée par spectrophotométrie atomique. (who.int)
  • This documentation was revised to add selenium data to the already publicly released erythrocyte protoporphyrin data. (cdc.gov)
  • In very preterm babies, low selenium is associated with an increased risk of complications. (cochrane.org)
  • Supplementing very preterm infants with selenium is associated with benefit in terms of a reduction in one or more episodes of sepsis. (cochrane.org)
  • Blood selenium concentrations in newborns are lower than those of their mothers and lower still in preterm infants. (cochrane.org)
  • In very preterm infants low selenium concentrations have been associated with an increased risk of chronic neonatal lung disease and retinopathy of prematurity. (cochrane.org)
  • Another important function of selenium is its role in the metabolism of thyroid hormones. (jakchang.com)
  • Iodine is an element of the thyroid hormones, which control metabolism, heat, and growth of various tissues such as the brain, and foetal development. (country-wide.co.nz)
  • Severe gastrointestinal disorders may affect the body's ability to absorb selenium. (medlineplus.gov)
  • We need fuel for these cells to function, provided by molecules, compounds, and chemical elements, yet 99% of our body's mass consists of just six elements. (discovery.com)
  • Biological functions and toxic effects of selenium on aquaculture animals and research advances of its mechanism. (cabi.org)
  • Selenium helps your body make special proteins, called antioxidant enzymes. (medlineplus.gov)
  • Since the discovery that selenium has its own genetic codeword, 25 human selenium-containing proteins have been discovered. (usda.gov)
  • About 30% of pastures contain insufficient selenium for livestock requirements. (country-wide.co.nz)
  • Vanadium is an example of a trace element which is suspected of having a use in the management of Type 2 diabetes, although there are insufficient studies to prove this. (infirmiers.com)
  • Because of its chemical similarity to sulfur and stronger nucleophilicity and acidity, selenium is an extremely efficient catalyst of reactions between sulfur and oxygen. (usda.gov)
  • At the invitation of Dr. Sassa, the EP Laboratory's routine method for EP was published as Unit 8.8 in Current Protocols in Toxicology, 1999 by J. Wiley & Sons, Inc. Elements of this protocol are reproduced below, but a reprint of the original publication is available from the EP lab director. (cdc.gov)
  • Optimization of selenium enrichment procedure for Tibetan kefir grains with antioxidant activity. (cabi.org)
  • Adverse effects of selenium intake are seen above 1500 µg/day, with "selenosis" and DNA damage occurring above 3000 µg/day [9] [10] . (zrtlab.com)
  • Selenium is an essential element for all forms of cellular life: it helps cells mop up damaging molecules called free radicals. (cosmosmagazine.com)
  • Supporting immune system function: Selenium plays a role in the activation and proliferation of certain immune cells, which can help to improve overall immune system function. (jakchang.com)
  • Selenium (Se) is an essential trace element for aquaculture animals, which plays an important role in maintaining normal growth, enhancing immune and antioxidant functions. (cabi.org)
  • Selenium protects cells and the immune system. (country-wide.co.nz)
  • Selenium enhances the immune response and has a specific effect on histamine. (saveourbones.com)
  • Selenium (Se) is an essential trace element for human and animal health, which has effects on anticancer, antioxidant, anti-cardiovascular diseases, strengthening antioxidant and immunity capacity, promoting growth and improving meat qualities, and so on [1] [2]. (scirp.org)
  • Selenium is required for the activity of the enzyme iodothyronine deiodinase, which converts the inactive form of thyroid hormone (T4) to the active form (T3). (jakchang.com)
  • Heat and exercise improve circulation and bring healing elements to the injury, speed their activity, and ferry debris, toxins, and pathogen carcasses away. (selfgrowth.com)
  • The activity leaves selenium traces in water courses. (cosmosmagazine.com)
  • The method is sensitive enough to be used to rapidly screen serum specimens from subjects suspected to be exposed to a number of important toxic elements or to evaluate environmental or other nonoccupationally exposure to these same elements. (cdc.gov)
  • It's also important to note that getting too much selenium can be harmful as well, which can cause symptoms such as hair loss, nail brittleness, diarrhea, skin rash, and anemia. (jakchang.com)
  • Earlier research suggests selenium may counter the harmful effects of arsenic, cadmium and lead. (medicalnewstoday.com)
  • Selenium has been seen mainly as an antioxidant that protects against the harmful effects of oxygen. (usda.gov)
  • Babies are born with lower selenium concentrations in their blood than their mothers. (cochrane.org)
  • The data are dominated by one large trial from a country with low selenium concentrations and may not be readily translated to other populations. (cochrane.org)
  • Two trials, including one trial with a much larger sample size than the others combined, were from geographical areas with low population selenium concentrations. (cochrane.org)
  • Cognitive function: Some studies have also suggested that selenium may have a role in cognitive function, although more research is needed to confirm this. (jakchang.com)