Toxicity substances. Medical search. Frequent questions

Acute toxicity occurs when you swallow too much of a lithium prescription at one time. (medlineplus.gov)
Acute-on-chronic toxicity occurs when you normally take lithium every day, but one day you take an extra amount. (medlineplus.gov)
We report two cases of acute intoxication associated with these substances. (erowid.org)
Cocaine may induce miscarriage, premature labor, placental abruption, or fetal toxicity, and modifications may be necessary for acute management. (medscape.com)
Thus, there is concern primarily about use of epinephrine, lidocaine, and beta-blockers in the setting of acute cocaine toxicity. (medscape.com)
Change in the new psychoactive substances associated with Emergency Department acute toxicity presentations associated with the introduction of the UK 2016 Psychoactive Substances Act. (austin.org.au)
The aim of this study was to determine whether this was associated with a change in Emergency Department (ED) presentations with acute NPS toxicity. (austin.org.au)
ED presentations to our inner-city hospital in London, UK, with acute NPS toxicity in the 12 months before and after the PSA introduction [June 2015-May 2016 (2015/2016) and June 2016-May 2017 (2016/2017)] were obtained from our database. (austin.org.au)
there is some evidence that acute toxicity from oral ingestion of the specified substance may be a factor in the development of the condition under consideration. (dva.gov.au)
23910 - the veteran has suffered from acute toxicity from oral ingestion of the specified substance at some time. (dva.gov.au)
23913 the veteran has suffered from acute toxicity from oral ingestion of organophosphorous insecticides at some time. (dva.gov.au)
23914 the veteran has suffered from acute toxicity from oral ingestion of carbamate insecticides at some time. (dva.gov.au)
23915 the veteran has suffered from acute toxicity from a paracetamol overdose at some time. (dva.gov.au)
23916 the veteran suffered from acute toxicity from oral ingestion of this specified substance within the seven days immediately before the clinical onset of the condition under consideration. (dva.gov.au)
23918 - the veteran has established the causal connection between the acute toxicity from oral ingestion of a specified substance and VEA service for the clinical onset of acute pancreatitis. (dva.gov.au)
23919 - the veteran has established the causal connection between the acute toxicity from oral ingestion of a specified substance and operational service for the clinical onset of acute pancreatitis. (dva.gov.au)
23920 - the veteran has established the causal connection between the acute toxicity from oral ingestion of a specified substance and eligible service for the clinical onset of acute pancreatitis. (dva.gov.au)
the acute toxicity from oral ingestion of this specified substance on operational service within the seven days immediately before the clinical onset of the condition under consideration was due to the veteran's serious default, wilful act or serious breach of discipline. (dva.gov.au)
on eligible service, the veteran has suffered from acute toxicity from oral ingestion of this specified substance within the seven days immediately before the clinical onset of the condition under consideration. (dva.gov.au)
Information is given on sources of depleted uranium exposure, the likely routes of acute and chronic intake, the potential health risks from both the radiological and chemical toxicity standpoints and future research needs. (who.int)

In Ontario, detailed data on fatal substance-related toxicities have largely been restricted to opioid toxicity deaths, with limited data available on the relative frequency of toxicity deaths attributable to alcohol, benzodiazepines, and stimulants, and the frequency of polysubstance use among these deaths. (nss-aps.ca)
The combination drug diphenoxylate/atropine (Lomotil) can produce signs of anticholinergic toxicity in addition to opioid toxicity. (medscape.com)

In addition to renal disease, cardiovascular effects, and reproductive toxicity, lead may cause irreversible neurologic damage. (cdc.gov)
Studies in animals have shown reproductive toxicity (see section 5.3). (who.int)
Animal studies are insufficient with respect to reproductive toxicity (see section 5.3). (who.int)
Animal studies do not indicate reproductive toxicity (see section 5.3). (who.int)

The Environmental Protection Agency (EPA) and the Agency for Toxic Substances and Disease Registry (ATSDR) prepare the National Priority List (NPL) which is a "list of national priorities among the known releases or threatened releases of hazardous substances, pollutants, or contaminants throughout the United States and its territories. (cdc.gov)
The Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), commonly known as the Superfund Act , requires the Agency for Toxic Substances and Disease Registry (ATSDR) to prepare toxicological profiles that examine hazardous substances on the NPL. (cdc.gov)
Initially, toxic substance information was organized by publication, so only those with prior knowledge of ATSDR publications could locate substance information easily. (cdc.gov)

Radioactive metals have both radiological toxicity and chemical toxicity. (wikipedia.org)
This is insignificant with respect to both chemical and radiological toxicity. (who.int)

Case Studies in Environmental Medicine (CSEM): self-instructional courses designed to teach primary care providers about hazardous substances and how to evaluate patients potentially exposed to them. (cdc.gov)

The key step within assignment of the hazard-specific SK is the determination of the hazard potential of the substance, or its potential for causing adverse health effects as a result of skin exposure. (cdc.gov)
Anyone can develop mercury toxicity as a result of mercury exposure. (epnet.com)
Learn how toxic substances can affect health and how to prevent exposure. (cdc.gov)
You can go to the Toxic Substance Portal to learn about the health hazards of these substances and the dangers of exposure. (cdc.gov)
Health care professionals can search the Toxic Substances Portal for specific information about health effects caused by exposure to toxic substances. (cdc.gov)
Exposure should be minimized even for substances of no known significant hazard, and special precautions should be taken for work with substances that present special hazards. (lu.se)
This is a priority list of 275 substances based on a combination of their frequency, toxicity, and potential for human exposure at National Priorities List - NPL - sites, with 1995 and 1997 ranks, nam. (bvsalud.org)

There were 1884 presentations with recreational drug toxicity, 447 (23.7%) involved NPS. (austin.org.au)
We know how to stop people dying from drug toxicity, can you please listen? (ccsa.ca)

2016. Prevention of Childhood Lead Toxicity. (cdc.gov)
In May 2016, the Psychoactive Substances Act (PSA) came into effect in UK making it an offence to produce or supply new psychoactive substances (NPS). (austin.org.au)

1993). "Mechanisms of chromium carcinogenicity and toxicity. (cdc.gov)
Mechanisms of chromium toxicity, carcinogenicity and allergenicity: review of the literature from 1985 to 2000. (cdc.gov)

Identifying the intrinsic hazards of substances that may have endocrine properties is a key step in risk management. (lifescientis.com)

Many metals, particularly heavy metals are toxic, but some heavy metals are essential, and some, such as bismuth, have a low toxicity. (wikipedia.org)

Patients with cocaine toxicity may be combative, aggressive, and disoriented, and have delusions of persecution or hallucinations. (medscape.com)
Patients with cocaine toxicity should receive initial evaluation and stabilization, including attention to ABCs, oxygen, intravenous access, and cardiac and pulse oximetry monitoring. (medscape.com)
Perform routine pregnancy testing for appropriate patients as physiologic changes in pregnancy may increase cocaine toxicity. (medscape.com)
[ 45 ] The American College of Cardiology Foundation/American Heart Association (ACCF/AHA) 2014 recommendations for treatment of patients with cocaine toxicity are based on class C evidence (ie, consensus opinion of experts, case studies, or standard of care). (medscape.com)
Vasopressin offers considerable theoretical advantage over epinephrine in cardiac arrest due to cocaine toxicity. (medscape.com)

The exceptional thermal and chemical stability and the amphiphilicity of per- and polyfluoroalkyl substances (PFAS) have resulted in widespread use and subsequent contamination in environmental media and biota. (pfascentral.org)

Projects to enhance the utility of bacteria to remediate or reduce the toxicity of environmental toxicity are proposed. (azregents.edu)
Risk of environmental impact of triamcinolone acetonide cannot be excluded, due to the lack of environmental toxicity data. (janusinfo.se)
In accordance with the Environmental Code´s substitution principle (SFS 1998:808 Chapter 2, Section 4) chemical products that are hazardous to health and the environment are to be substituted, by substances that are less hazardous, through active product selection and substitution. (lu.se)

A new group of novel psychoactive substance, the N-methoxybenzyl (NBOMe) derivatives of substituted phenethylamine, has recently emerged on the drug market, among which 25I-NBOMe and 25B-NBOMe have previously been implicated in clinical intoxications and fatalities. (erowid.org)

By contrast, substances found to cause reversible irritation to rabbits' eyes have nearly a 60% chance of being found harmless in a later test. (scientificamerican.com)

It will be a new instrument to evaluate unpredictable toxicity due to synergistic effects of different chemicals, additionally worsened by the human ageing process. (europa.eu)
For this reason, the skin is often exposed to potentially hazardous agents, including chemicals, which may contribute to the onset of a spectrum of adverse health effects ranging from localized damage (e.g., irritant contact dermatitis and corrosion) to induction of immune-mediated responses (e.g., allergic contact dermatitis and pulmonary responses), or systemic toxicity (e.g., neurotoxicity and hepatoxicity). (cdc.gov)
The EC Inventory is a combination of three independent European lists of substances from the previous EU chemicals regulatory frameworks (EINECS, ELINCS and the NLP-list). (europa.eu)
Health risks of nearly 10,000 chemicals charted to help predict toxicity of untested substances. (scientificamerican.com)
A giant database on the health risks of nearly 10,000 chemicals will make it easier to predict the toxicity of tens of thousands of consumer products for which no data exist, say researchers. (scientificamerican.com)
With the database, Hartung hopes that companies and regulators will find it easier to infer the toxic effects of untested substances by comparing them with structurally or biologically similar chemicals with known effects-a method called read-across. (scientificamerican.com)
ATSDR's Toxic Substances Web Portal makes it easy for researchers and citizens to find information about toxic chemicals and related health effects. (cdc.gov)

This joint report by the ODPRN and Public Health Ontario provides an overview on the trends and patterns of single and polysubstance (more than one substance) deaths from alcohol, benzodiazepines, opioids, and stimulants in Ontario (January 2018 to December 2021). (nss-aps.ca)
However, transdermal patches can contribute to the toxicity of orally or parentally administered opioids. (medscape.com)

As such once the IUCLID format change begins on 19th May 2023 we will no longer update REACH registered substance factsheets. (europa.eu)

Polysubstance use complicates substance toxicity responses, resulting in higher fatality rates compared to when substances are used alone. (nss-aps.ca)

This risk analysis makes it possible to evaluate products and substances in their context of use by combining different scientific approaches (identification of the danger, risk, weight of proof, PDO, mode of action). (lifescientis.com)
The focus f this proposal is to develop methods to detect, evaluate and understand the toxicity of hazardous substances tin the environment of dump sites and to enhance the utility of bacterial degradation as a procedure to reduce the amount and toxicity of hazardous substances. (azregents.edu)

Treatment of thallium toxicity consists of initial stabilization, prevention of absorption, enhanced elimination, and antidotal therapy. (medscape.com)

Computational Tools and Techniques to Predict Aquatic Toxicity of Some Halogenated Pollutants. (igi-global.com)

1992). Mercury toxicity. (bvsalud.org)

This article focuses on lithium overdose, or toxicity. (medlineplus.gov)

Agency for Toxic Substances and Disease Registry (2000). (cdc.gov)

The identification of genetic factors associated with either responsiveness or resistance to 5-fluorouracil (5-FU) chemotherapy, as well as genetic factors predisposing patients to the development of severe 5-FU-associated toxicity, is increasingly being recognised as an important field of study. (nih.gov)
The 'Substance identity' section is calculated from substance identification information from all ECHA databases. (europa.eu)

5 Things to Know About CDC Yellow Book 2024 The updated book provides key information to discuss with your traveling patients, from vaccine recommendations to the policies and risks associated with substance use in other countries. (medscape.com)

Which of these groups is usually designated as one of the most sensitive sub-populations for exposures to toxic substances? (cdc.gov)

We hypothesized that digoxin toxicity has declined in recent years, and that the decline is accompanied by reductions in overall utilization and dose. (nih.gov)
To analyze trends in digoxin toxicity and utilization from 1991 to 2004, we used surveys from the National Center for Health Statistics and Medicaid data in the United States and The Health Improvement Network (THIN) database in the United Kingdom. (nih.gov)
AFB 1 has the strong liver toxicity and can reduce production performance, feed utilization [ 3 ], egg production, and immunosuppression in poultry [ 5 ]. (hindawi.com)

By introducing an in vitro cardiac system and ML models, ALTERNATIVE will provide a platform able to refine, reduce and replace the need for animal testing, providing close-to-real scenario information on toxicity and achieving a significant reduction of the associated direct and indirect costs. (europa.eu)
The reduction in toxicity was directly correlated to a decrease in the concentration of 2,4-DCP in the treated solutions, as measured by high-performance liquid chromatography. (njit.edu)

Indeed, according to the definition of the European Union, "an endocrine disruptor is a substance or an exogenous mixture which alters the function (s) of the endocrine system and, consequently, causes harmful effects on health. (lifescientis.com)
This review also summarized some exogenous regulatory substances that can alleviate AFB 1 -induced oxidative stress. (hindawi.com)
This review summarizes and discusses the possible mechanisms of ducks' high sensitivity to AFB 1 and the feasibility of regulating ducks' AFB 1 metabolism through exogenous substances, thereby enhancing ducks' tolerance to AFB 1 . (hindawi.com)
This article is aimed at providing a theoretical basis for the research of exogenous substances to prevent and regulate duck aflatoxin poisoning. (hindawi.com)

Insoluble compounds as well as the metallic forms often exhibit negligible toxicity. (wikipedia.org)
It also provides an overview of the occurrence, source, and fate of metallic substances in the environment, as well as their control by regulations and standards. (routledge.com)

"Research Findings on Smoking of Abused Substances" NIDA Research Monographs . (erowid.org)
To understand the particular toxicity associated with smoking, it is necessary to integrate research findings in several areas. (erowid.org)

Bioaccumulation: Log K ow = 1.16 (PubChem Hazardous Substances Data Bank). (janusinfo.se)

The portal provides comprehensive access to the best science and the latest research for approximately 300 chemical substances. (cdc.gov)

Although the role of tumoral levels as a prognostic factor for clinical responsiviness has not been firmly established, there is ample evidence that a deficiency of DPD is associated with severe toxicity after the administration of 5-FU. (nih.gov)
Healthcare providers who can use free evidence-based medical education courses addressing the clinical health effects of hazardous substances. (cdc.gov)
Suspicion of co-ingestants should be nurtured when the patient's clinical course does not conform closely to known opiate effect profiles, especially given the cardiac toxicity of the tricyclics. (medscape.com)

There is a search engine that facilitates finding substances by substance name, CAS number (Chemical Abstract Service registry number), synonym, or trade name. (cdc.gov)

The results, published alongside the description of the database, suggest that substances found to cause serious irreversible eye damage in one test have a 10% chance of being found harmless in a subsequent test. (scientificamerican.com)

Protective role of l-threonine against cadmium toxicity in Saccharomyces cerevisiae. (greenmedinfo.com)
What about the toxic substances we hear about in the news-mercury in canned tuna, BPA in plastic, cadmium in jewelry? (cdc.gov)

Asbestos Toxicity: What Is the Biological Fate of Asbestos? (cdc.gov)

In comparative 13-week studies conducted to determine the structure-toxicity relationships of o-, m-, and p-chloroaniline, groups of 10 male and 10 female F344/N rats and B6C3F1 mice were administered 0, 10, 20, 40, 80, or 160 mg o- or m-chloroaniline per kilogram body weight in dilute hydrochloric acid by gavage. (nih.gov)
In conclusion, chloroaniline isomers are hematotoxic and have the same pattern of toxicity in rats and mice. (nih.gov)

Asbestos, formaldehyde, arsenic, lead-many of us know that these substances are potentially dangerous. (cdc.gov)

A) In the wastewater: oxygen-consuming substances (lignin and cellulose decomposition), dyes B) In treated sludge: organic and inorganic solids (incl. (nzdl.org)

Chronic toxicity occurs when you slowly take a little too much of a lithium prescription every day for a while. (medlineplus.gov)
Mercury toxicity occurs when a person is exposed to mercury. (epnet.com)

Before beginning an experiment, know what specific action to take in the event of accidental release of any hazardous substance. (lu.se)

Although the o-, m-, and p- isomers of chloroaniline all exhibit genetic toxicity, the profiles of activity among the three isomers are not identical. (nih.gov)

At the end of the 10 day window covering the period from day 2 to 12, the BOD was 85%+/-2% of the ThOD for complete oxidation of the test substance. (europa.eu)

Facilitates conversations and increases awareness of the stigma that surrounds people who use substances, their support networks and service providers in the community. (ccsa.ca)

Genetic toxicity studies of o- and m-chloroaniline in vivo and in vitro were also conducted. (nih.gov)

The nanoforms of some substances may differ from their conventional forms in terms of physicochemical properties, biokinetic behavior and / or biological effects. (lifescientis.com)
So, in the fall of 2010, the Toxic Substances Portal was launched to provide an easy, user-friendly "one-stop shop" for anyone seeking information on the health effects of toxic substances. (cdc.gov)
The Toxic Substances Portal features clean lines, text matched to graphics, and three featured sections with easy click access to a large amount of health effects information. (cdc.gov)
ToxFAQs: fact sheets written in plain language that answer the most frequently asked questions about a toxic substance and its health effects. (cdc.gov)
Cardiac effects also may be observed with propoxyphene toxicity because of its quinidinelike effects. (medscape.com)

In addition, the onset of toxicity occurred twice as fast compared with patients with a normal DPD activity. (nih.gov)

The effect of a synthetic iron(III)-porphyrin meso-tetra(2,6-dichloro-3-sulfonatophenyl)porphyrinate as a biomimetic catalyst in the oxidative treatment of 2,4-dichlorophenol (2,4-DCP) with humic substances and H 2 O 2 was evaluated in factorial design experiments conducted at different concentrations of 2,4-DCP (0-25 ppm) and different incubation treatment times (0, 24, 96, or 120 h). (njit.edu)
In the absence of this treatment, bioassays with the bacterium Pseudomonas putida (ATCC11250) showed decreasing specific growth rates μ (used here to quantify 2,4-DCP toxicity) with increasing concentrations of 2,4-DCP. (njit.edu)

Therefore, a common characteristic of toxic metals is the chronic nature of their toxicity. (wikipedia.org)

Anatomy9

Organisms10

Diseases34

Chemicals and Drugs89

Analytical, Diagnostic and Therapeutic Techniques and Equipment59

Psychiatry and Psychology17

Phenomena and Processes27

Disciplines and Occupations2

Anthropology, Education, Sociology and Social Phenomena6

Technology, Industry, Agriculture3

Information Science7

Named Groups2

Health Care30

Geographicals1

Acute20

Opioid toxicity2

Reproductive4

ATSDR3

Radiological toxicity2

Case Studies in Environmental Medicine1

Exposure7

Drug toxicity2

20162

Carcinogenicity2

Hazards1

Heavy metals1

Cocaine5

Polyfluoroalkyl1

Environmental3

Psychoactive1

Irritation1

Chemicals7

Opioids2

20231

Responses1

Evaluate2

Prevention1

Pollutants1

19921

Overdose1

Disease Registry1

IDENTIFICATION2

Risks1

Exposures1

Utilization3

Reduction2

Exogenous4

Metallic2

Findings2

Bioaccumulation1

Chemical substances1

Clinical3

Abstract1

Irreversible1

Cadmium2

Fate1

Mice2

Asbestos1

Wastewater1

Occurs2

Hazardous substance1

Profiles1

Oxidation1

Stigma1

Genetic1

Effects5

Onset1

Concentrations2

Chronic1