• America's all-time-leading heartless anti-science zealot EPA Administrator Scott "Mr. Toxicity" Pruitt, as of March 2017, nixed his own agency's proposal of 2015 to ban the toxic chemical chlorpyrifos, an insecticide that attacks the nervous system of pesky insects, as well as pesky and non-pesky people (the Nazis invented it for germ warfare). (counterpunch.org)
  • 2. As M. Lee mentioned in a related posting, once you have this Registry number, you can use it to search in other abstract-containing files, like CAplus, in combination with search terms like toxicity, plants, etc. to find the kind of information you're interested in. (bio.net)
  • These images are a random sampling from a Bing search on the term "Anticholinergic Toxicity. (fpnotebook.com)
  • I search information about human toxicity of aldicarb=Temik,carbamate pesticide,and especially about toxic doses and lethal doses for human. (bio.net)
  • Most patients with MDMA overdose improve with supportive care, but life-threatening complications may result from severe toxicity (see Treatment ). (medscape.com)
  • This article focuses on lithium overdose, or toxicity. (medlineplus.gov)
  • Ivermectin toxicity is seen when an overdose of the drug ivermectin is administered or consumed or in pets with increased sensitivity to the drug. (petplace.com)
  • If there is a high probability of colchicine toxicity, for example because of intentional overdose or dose in excess of 6mg in high risk patients, prompt admission to a facility with access to intensive supportive treatment is essential. (medsafe.govt.nz)
  • Because individuals typically have different levels of response to the same dose of a toxic substance, a population-level measure of toxicity is often used which relates the probabilities of an outcome for a given individual in a population. (wikipedia.org)
  • We identified RNA sequence determinants of toxicity and evolved suppressor strains that can tolerate the expression of toxic GFP variants. (pnas.org)
  • The first signs of toxicity generally occurs within six hours of eating a toxic amount of iron. (petplace.com)
  • The Human Stress & Toxicity RT² Profiler PCR Array profiles the expression of 84 key genes regulated during cellular responses to stress and toxic compounds. (qiagen.com)
  • Others have also written to ask why they can't read the abstract of the vitamin A toxicity paper. (vitamindcouncil.org)
  • Here is a link to the publisher where you will find the full citation of our paper: Cod Liver Oil, Vitamin A Toxicity, Frequent Respiratory Infections, and the Vitamin D Deficiency Epidemic-unfortunately, the publisher will charge you $20.00 to view the full paper. (vitamindcouncil.org)
  • Vitamin A toxicity in dogs most often occurs accidentally or inadvertently. (vetinfo.com)
  • Let's find out how vitamin A helps your dog, what a case of vitamin A toxicity looks like and what steps should be taken to resolve the problem in your dog. (vetinfo.com)
  • Vitamin A toxicity can occur when a dog ingests too much vitamin A. Sometimes this occurs accidentally, as when a puppy consumes a bottle of vitamin A supplements, but in other cases, it occurs inadvertently when an owner gives a dog too much vitamin A. These cases include overuse of fish liver oil supplements or overfeeding of liver. (vetinfo.com)
  • Your veterinarian will diagnose vitamin A toxicity in your pet using diagnostic tests, x-rays and an evaluation of your dog's medical history. (vetinfo.com)
  • Your dog's diet may also need to be changed if he has been regularly consuming large amounts of liver to prevent further occurrences of vitamin A toxicity. (vetinfo.com)
  • Toxicity can refer to the effect on a whole organism, such as an animal , bacterium , or plant , as well as the effect on a substructure of the organism, such as a cell ( cytotoxicity ) or an organ such as the liver ( hepatotoxicity ). (wikipedia.org)
  • A major reason is that it's difficult to predict the response of the liver, where drug toxicity often shows up. (technologyreview.com)
  • Liver toxicity issues are the primary reason for drug recall and withdrawal," according to Yvonne Dragan, director of systems toxicology at the FDA's National Center for Toxicological Research. (technologyreview.com)
  • So it's not surprising that mimicking liver toxicity in the lab would be the centerpiece of efforts to predict a drug's toxicity early in the development process. (technologyreview.com)
  • Bhatia is not the only researcher working on using liver cells to better predict toxicity. (technologyreview.com)
  • Although the danger of this is much less than problems with the liver, it usually becomes evident after liver toxicity, and can complicate severe hepatic failure. (selfgrowth.com)
  • Unexpected liver toxicity derailed a phase I melanoma trial of concurrent treatment with the first two targeted agents approved for the disease, according to a brief communication from investigators. (medpagetoday.com)
  • Additionally, overlapping skin and liver toxicity rarely limit use of either drug, the authors noted. (medpagetoday.com)
  • After surviving iron toxicity, your dog may not have full function of the liver or gastrointestinal tract and specific lifetime medications and special diets may be necessary. (petplace.com)
  • Toxicity in mammals includes a wide range of animals and effects such as liver cirrhosis, necrosis in kidneys and the brain, gastrointestinal distress, lesions, low blood pressure, and fetal mortality. (wikipedia.org)
  • Please join this discussion about Ranking Orals - Liver Toxicity within the Anabolic Steroids category. (elitefitness.com)
  • Some believe that all C17AA's are about the same in regard to liver toxicity, but others disagree and believe that they rank somewhere in this order. (elitefitness.com)
  • Acute toxicity occurs when you swallow too much of a lithium prescription at one time. (medlineplus.gov)
  • Evidence also has accumulated to implicate glucose toxicity in the functional impairment in insulin secretion that occurs during the initial presentation of patients with type I diabetes, and this may explain the honeymoon period so commonly observed after the institution of insulin therapy. (diabetesjournals.org)
  • Iron toxicity most commonly occurs in dogs after accidental ingestion of the supplements or from overdoses of supplements. (petplace.com)
  • One good online source of plant toxicity information is STN, the Science and Technical Information Network, produced by the organization I work at, Chemical Abstracts Service. (bio.net)
  • A lot of people think that Chemical Abstracts and STN have only purely chemical information, but, a third of all the abstracts (journals, patents, conference proceedings, etc.) we put out every year come from our bio-related areas and include plant toxicity abstracts like the above ones. (bio.net)
  • Boron is an interesting element since it is essential to crop growth in small soil concentrations (0.2-1.5 ppm) yet may produce plant toxicity in plants as the soil concentration increases over 2.5 ppm (Reisenauer et al. (redorbit.com)
  • and (3) to identify aldehyde-induced cardiovascular toxicity in humans. (fda.gov)
  • To address Aim 3, researchers will use banked blood and urine samples from 350 high-risk cardiovascular disease patients (adult smokers and nonsmokers over age 21 already enrolled in the Louisville Healthy Heart Study) to evaluate whether the cardiovascular toxicity profiles in human smokers are comparable to patterns of aldehyde-induced toxicity in mice. (fda.gov)
  • Study findings will provide information about how major aldehydes present in cigarette smoke and e-cigarette aerosols contribute to cardiovascular toxicity. (fda.gov)
  • The possible neurological and cardiovascular toxicity could make such an intervention potentially dangerous. (health.gov.au)
  • In 2005, researchers at UT El Paso, showed that the cell toxicity effect of carbon-nanotubes was essential identical to that of chrysotile asbestos. (dailytech.com)
  • Faculty members on the Health Science Campus of the University of Toledo propose to address four key issues in the areas of hepatic toxicity of microcyctin, measurement of microcystin levels in biological samples, microbiological approaches to solve the crisis, and treatment of hospital water system. (utoledo.edu)
  • Toxicity issues and adverse events associated with ARVs are currently identified only intermittently and not being widely reported. (who.int)
  • The development of local anesthetics to provide prolonged analgesia from a single injection has encountered 3 principal challenges: inadequate duration of action, systemic toxicity, and adverse local tissue reaction. (pnas.org)
  • Serious toxicity with colchicine is an adverse reaction of current concern. (medsafe.govt.nz)
  • Limitations of toxicity characterization in life cycle assessment - can adverse outcome pathways provide a new foundation? (environmental-expert.com)
  • The predicted no effects concentration (PNEC) is calculated from toxicity tests to determine the concentration that is not thought to cause adverse effects to aquatic organisms. (wikipedia.org)
  • Certain life stages are more susceptible to adverse effects, which is why early life stage (ELS) toxicity tests are performed for certain aquatic species. (wikipedia.org)
  • However, there is a harsh penalty for the dentist who recommends removing fillings because of mercury toxicity. (healthy.net)
  • The EPA has launched a multi-year process to revise its assessment of mercury toxicity. (ewg.org)
  • and it may help to explain why some people ae predisposed to mercury toxicity due to differences in genetics, metabolism, and gut bacteria, said Matthew Rand, Ph.D. , assistant professor of Environmental Medicine, who led the proof-of-concept study. (rochester.edu)
  • Toxicity results in any number or combination of clinical signs ranging from mild to extremely severe, including death. (petplace.com)
  • The consequences of toxicity are staggering - we are feeling sick and tired, and we are developing severe debilitating degenerative diseases, on top of ever increasing risks for birth defects. (life-enthusiast.com)
  • A selective inhibitor of T-cell activation, belatacept "allows effective immunosuppression, better preservation of renal function, and improved cardiovascular/metabolic risk profile and less toxicity compared with calcineurin inhibitors," Flavio Vincenti, MD, of the University of California San Francisco, and colleagues concluded in reporting the first trial. (medpagetoday.com)
  • The drug's specificity for inhibiting T-cell activation is thought to allow effective immunosuppression without the renal and nonrenal toxicities associated with calcineurin inhibitors, Vincenti and co-authors wrote. (medpagetoday.com)
  • Increased colchicine toxicity, due to delayed renal excretion, is the end result of these pharmacodynamic effects. (medsafe.govt.nz)
  • Corrosive chemicals possess physical toxicity because they destroy tissues, but they're not directly poisonous unless they interfere directly with biological activity. (wikipedia.org)
  • Cardiac toxicity is damage to the heart by harmful chemicals. (nccn.org)
  • 1994), 13(3), 509-15 CC 4-3 (Toxicology) My Note: Studies toxicity of anthracene and other chemicals by using peroxidase assay. (bio.net)
  • The Microtox CTM is a site-based, broad range monitor that continuously measures the chemical toxicity of several thousand chemicals in any water source and is able to give an instant indication of the water quality. (environmentalleader.com)
  • Researchers of the Environmental Microbiology Group of the UAB Department of Genetics and Microbiology have developed a paper-based biosensor covered with bacteria to detect water toxicity. (eurekalert.org)
  • Using a material such as paper and without the need of complex tools makes this biosensor a simple and inexpensive technique which can be used to detect toxicity in contexts of economic restrictions or in developing countries, researchers indicate. (eurekalert.org)
  • Some researchers believe that mitochondrial toxicity contributes to the fat redistribution (lipodystrophy) associated with anti-HIV therapy. (thebody.com)
  • Ammonia toxicity as a criterion for the evaluation of larval quality in the prawn Macrobrachium rosenbergii. (thefreedictionary.com)
  • Similar pH levels with different stocking density helped in keeping the ammonia toxicity at low levels. (thefreedictionary.com)
  • These results indicate that the apparent threshold concentration of ammonia toxicity for oocytes from porcine under in vitro conditions (200 to 300 [micro]M) is greater than the levels oocytes are exposed to as a large follicle during nuclear maturation (170 [micro]M). (thefreedictionary.com)
  • With rapid scale up of antiretroviral therapy (ART) and the increasing use of antiretrovirals (ARVs) to prevent HIV, the need to monitor toxicity of these drugs has increased substantially. (who.int)
  • Every year unforeseen toxicity scuttles new drugs, sometimes even after they've received FDA approval. (technologyreview.com)
  • To allow increased loading without systemic toxicity, we used liposomes, which are biocompatible microscopic lipid vesicles with a bilayer membrane structure that have been used to deliver hydrophilic, amphiphilic, and hydrophobic drugs. (pnas.org)
  • Quality control of each batch of drugs produced and regular monitoring for toxicity is required when antimonials are used therapeutically. (mdpi.com)
  • The increasing use of a variety of postindustrial wastes believed to be benign in the compost process raises the concern of presence and toxicity of xenobiotics, defined as compounds that have been introduced into the environment by artificial means at any point in their useful cycle, and which may or may not later exert harmful influences if present in composts. (redorbit.com)
  • The objective of the 14-day studies is to determine the starting dosages for the 28-day studies based on clinical signs, whereas the objective of the sub-acute studies is to observe and quantify toxicity in all organs, especially the nasopharyngeal tissue, respiratory tract and lungs. (fda.gov)
  • Overall, treatment of psychostimulant toxicity should involve prompt supportive care and judicious use of specific agents. (health.gov.au)
  • The paper changes colours according to the intensity of the cell metabolism of the bacteria, inversely proportional to the toxicity of the sample: the more the colour changes, the less contamination detected. (eurekalert.org)
  • Note: If subject received major surgery, they must have recovered adequately from the toxicity and/or complications from the intervention prior to starting therapy. (tripdatabase.com)
  • Some of these important developments have been the delineation of mechanisms of NSAID-induced GI toxicity, identification of groups at highest risk for development of NSAID-induced gastrointestinal complications, recognition of co-therapies that could reduce NSAID toxicity, and, most recently, development of classes of NSAIDs that have an improved gastrointestinal safety profile. (nih.gov)
  • Toxicity can be measured by its effects on the target (organism, organ, tissue or cell). (wikipedia.org)
  • Formulations have often been limited in duration of action, or by systemic toxicity, local tissue toxicity from local anesthetics, and inflammation. (pnas.org)
  • At the root of MDMA's widespread popularity is the mistaken belief that it is a safe drug with little toxicity and a long duration of action. (medscape.com)
  • Physiological action and toxicity of the drug. (medindia.net)
  • Explain to patients that a new drug for kidney transplantation led to outcomes at least as good as those observed with an older drug but with less toxicity. (medpagetoday.com)
  • Diffuse Large B-Cell Lymphoma Refractory Follicular Lymphoma Refractory Mediastinal (Thymic) Large B-Cell Cell Lymphoma Other: Laboratory Biomarker Analysis Biological: Pembrolizumab Drug: Vorinostat Phase 1 Detailed Description: PRIMARY OBJECTIVES: I. To assess the safety and tolerability of vorinostat plus pembrolizumab therapy by evaluation of toxicities including: type, frequency, severity, attribution, time course and duration. (tripdatabase.com)
  • In addition, minimizing toxicity remains one of the major barriers to bringing a drug to market. (qiagen.com)
  • LTG toxicity should be considered in patients taking this drug who have depressed mental status. (wiley.com)
  • goot shit.Anadrol- Good shit but effective dosing begins around 50mgs ED MINIMUM so not the most reasonable drug in terms of gains versus toxicity. (elitefitness.com)
  • A mg of 17-alpha-alkylated drug is a mg of 17-alpha-alkylated drug in terms of toxicity. (elitefitness.com)
  • This book provides with a comprehensive overview of the role of drug transporters in drug disposition and efficacy/toxicity, as well as drug-drug interactions and recent advances in the field. (springer.com)
  • Anti-HIV drug side effects linked to mitochondrial toxicity have been around for years. (thebody.com)
  • Ideal ENM libraries should also include positive and negative control ENMs to provide a reference point for the evaluation of material toxicity. (sigmaaldrich.com)
  • Other more common conditions related to mitochondrial toxicity include myopathy (muscle cell destruction and weakness), peripheral neuropathy (numbness and tingling in fingers and toes) and pancreatitis (inflammation of the pancreas). (thebody.com)
  • Cobalt toxicity - an emerging clinical problem in patients with metal-on-metal hip prostheses? (mja.com.au)