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  • LD50
  • Assignment to a toxicity class is based typically on results of acute toxicity studies such as the determination of LD50 values in animal experiments, notably rodents, via oral, inhaled, or external application. (wikipedia.org)
  • toxin
  • Annual ryegrass toxicity (ARGT) is the poisoning of livestock from toxin contained in bacterially infected annual ryegrass (Lolium rigidum). (wikipedia.org)
  • causes
  • While the exact causes of mitochondrial toxicity are unknown, research has shown that a certain group of anti-viral drugs used to treat HIV, specifically nucleoside analog reverse transcriptase inhibitors (NRTIs), interfere with an enzyme needed in the production of mitochondria. (wikipedia.org)
  • Acute toxicity of pesticides causes a range of effects on bees, which can include agitation, vomiting, wing paralysis, arching of the abdomen similar to sting reflex, and uncoordinated movement. (wikipedia.org)
  • refers
  • Copper toxicity, also called copperiedus, refers to the consequences of an excess of copper in the body. (wikipedia.org)
  • Toluene toxicity refers to the harmful effects caused by toluene on the body While a significant amount of toluene, 25%-40%, is exhaled unchanged via the lungs, a greater proportion is metabolised and excreted via other pathways. (wikipedia.org)
  • occurs
  • Evidence also has accumulated to implicate glucose toxicity in the functional impairment in insulin secretion that occurs during the initial presentation of patients with type I diabetes, and this may explain the honeymoon period so commonly observed after the institution of insulin therapy. (diabetesjournals.org)
  • Protein toxicity occurs when the body is unable to get rid of the potentially toxic wastes that are generated as a result of protein metabolism, it may be also caused by kidney failure. (wikipedia.org)
  • Protein toxicity occurs when an individual with impaired kidney function consumes protein rich diet. (wikipedia.org)
  • Digoxin toxicity, also known as digoxin poisoning, is a type of poisoning that occurs in people who take too much of the medication digoxin or eat plants such as foxglove that contain a similar substance. (wikipedia.org)
  • seizures
  • Central nervous system oxygen toxicity can cause seizures, brief periods of rigidity followed by convulsions and unconsciousness, and is of concern to divers who encounter greater than atmospheric pressures. (wikipedia.org)
  • effects
  • Toxicity can be measured by its effects on the target (organism, organ, tissue or cell). (wikipedia.org)
  • Toxicity in mammals includes a wide range of animals and effects such as liver cirrhosis, necrosis in kidneys and the brain, gastrointestinal distress, lesions, low blood pressure, and fetal mortality. (wikipedia.org)
  • The toxicity class generally does not address issues of other potential harm of the agent, such as bioaccumulation, issues of carcinogenicity, teratogenicity, mutagenic effects, or the impact on reproduction. (wikipedia.org)
  • The predicted no effects concentration (PNEC) is calculated from toxicity tests to determine the concentration that is not thought to cause adverse effects to aquatic organisms. (wikipedia.org)
  • Certain life stages are more susceptible to adverse effects, which is why early life stage (ELS) toxicity tests are performed for certain aquatic species. (wikipedia.org)
  • It is important to note that not all fish have the same types or number of receptor proteins making olfactory toxicity and the subsequent effects species specific. (wikipedia.org)
  • The acute toxicity, although more lethal, is less common than sub-lethal toxicity or cumulative effects. (wikipedia.org)
  • copper
  • This includes pH, salinity, water hardness, conductivity, temperature, and amounts of dissolved organic carbon (DOC) For instance, the toxicity of copper is decreased with increasing amounts of DOC, as described by the biotic ligand model (BLM). (wikipedia.org)
  • Many studies have indicated copper as a source of olfactory toxicity in fishes, among other common substances. (wikipedia.org)
  • The investigation of the toxicity of mercury and copper to the olfactory systems in fish began in the early 1970s. (wikipedia.org)
  • Copper, cadmium, lead, and zinc are common metals that cause olfactory toxicity in fish. (wikipedia.org)
  • arrhythmias
  • This antidote has been shown to be highly effective in treating life-threatening signs of digoxin toxicity such as hyperkalemia, hemodynamic instability, and arrhythmias. (wikipedia.org)
  • cause
  • When methanol is broken down by the body it results in formaldehyde, formic acid, and formate which cause much of the toxicity. (wikipedia.org)
  • This strain can lead to proteins being inadequately metabolized and subsequently cause toxicity. (wikipedia.org)
  • CCB toxicity can cause a number of electrocardiogram abnormalities with a low sinus rhythm being the most common. (wikipedia.org)
  • Their toxicity to dogs can cause the animal to develop acute kidney injury (the sudden development of kidney failure) with anuria (a lack of urine production). (wikipedia.org)
  • pesticides
  • The Indian standardized system of toxicity labels for pesticides uses a 4-color system (red, yellow, blue, green) to plainly label containers with the toxicity class of the contents. (wikipedia.org)
  • Agencies such as the EPA and EFSA are making action plans to protect bee health in response to calls from scientists and the public to ban or limit the use of the pesticides with confirmed toxicity. (wikipedia.org)
  • mammals
  • Oil toxicity generally affects terrestrial mammals that feed on other affected animals that are directly exposed to oil. (wikipedia.org)
  • Oil toxicity affects a variety of marine mammals, including sea otters (Enhydra lutris), whales (Order: Cetacea), dolphins (Suborder: Odontoceti), seals (Clade: Pinnipedia), and manatees (Trichechus spp. (wikipedia.org)
  • metabolism
  • In people with healthy kidney function, the kidneys work continuously to excrete the by-products of protein metabolism which prevents protein toxicity from occurring. (wikipedia.org)
  • syndrome
  • It is also known as oxygen toxicity syndrome, oxygen intoxication, and oxygen poisoning. (wikipedia.org)
  • By definition, modes of action are characterized by FATS because the combination of common responses that represent each fish acute toxicity syndrome characterize an adverse biological effect. (wikipedia.org)
  • include
  • A lot of people think that Chemical Abstracts and STN have only purely chemical information, but, a third of all the abstracts (journals, patents, conference proceedings, etc.) we put out every year come from our bio-related areas and include plant toxicity abstracts like the above ones. (bio.net)
  • Other ECG changes that suggest digoxin toxicity include bigeminal and trigeminal rhythms, venticular bigeminy, and bidirectional ventricular tachycardia. (wikipedia.org)
  • kidney
  • Protein toxicity is the effect of the buildup of protein metabolic waste compounds due to insufficient kidney function. (wikipedia.org)
  • Several studies, however, have found no evidence of protein toxicity due to high protein intakes on kidney function in healthy people. (wikipedia.org)
  • substances
  • Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism . (wikipedia.org)
  • Research on the study of membrane toxicity has advanced a great deal in a relatively short period of time, prompting scientists to re-examine the problems associated with carriers, receptors and reactors to toxic substances. (springer.com)
  • mainly
  • ARV toxicity monitoring not only addresses toxicity associated to the long-term use of ARVs, but also the use of ARVs during pregnancy and breastfeeding, in infants and children, and by people who use them mainly to prevent HIV infection, such as in serodiscordant couples. (who.int)
  • Toxicity received mainly positive ratings and reviews from critics, getting a 5 out of 5 star rating from AllMusic, a 5/5 rating from Kerrang! (wikipedia.org)