• The arbitrary primer polymerase chain reaction (AP-PCR) and Southern blot restriction fragment length polymorphism (RFLP) were used to genotype the periodontal pathogen A. actinomycetemcomitans. (upenn.edu)
  • Southern blot RFLP analysis revealed 12 hybridization patterns consisting of 1 or 2 DNA fragments (2-23 kb). (upenn.edu)
  • There are many advantages to AFLP when compared to other marker technologies including randomly amplified polymorphic DNA (RAPD), restriction fragment length polymorphism (RFLP), and microsatellites. (wikipedia.org)
  • Genotyping of the APOA1 was performed by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) combined with gel electrophoresis, and then confirmed by direct sequencing. (biomedcentral.com)
  • Segregation analysis and exclusion of the mutations T224R and T369S in 100 control subjects (200 chromosomes) was performed by restriction fragment length polymorphism (RFLP) analysis of PCR-amplified fragments, including all available family members. (jneurosci.org)
  • The UTS2 gene polymorphisms were analyzed by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). (bjbms.org)
  • Genotyping of CYP1A1 T3801C polymorphisms and GSTM1/GSTT - null was made, respectively, by PCR-RFLP and multiplex PCR. (springeropen.com)
  • Eleven RFLP clones and 4 restriction enzymes combinations were used to probe the genomic DNA. (cmich.edu)
  • C SNPs were measured by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). (biomedcentral.com)
  • Genetic diversity in nested PCR products was determined by Restriction Fragment Length Polymorphism (RFLP) utilizing Alu1 and PstI restriction enzymes for alpha and beta gene products digestion, respectively. (scielo.br)
  • The aim of this study was to detect carriers of CVM in Holstein population using Polymerase Chain Reaction- Primer-introduced restriction analysis and Restriction Fragment Length Polymorphism (PCR-PIRA and RFLP) methods. (researchgate.net)
  • The polymorphism of the Serine-Rich Entamoeba dispar Protein (SREDP) gene among 8 isolates obtained from Iranian cyst carriers were analyzed by a nested PCR-RFLP followed by sequencing of the PCR products. (scialert.net)
  • A was analyzed by PCR-restriction fragment length polymorphism (PCR-RFLP) for further case-control association analysis. (biomedcentral.com)
  • A series of restriction fragment-length polymorphism (RFLP) and phenotypic markers distributed throughout the sweet corn genome were used to construct a genetic linkage map for each population. (agri.gov.il)
  • In the suI seI population genomic regions significantly influencing emergence across all four environments were found associated with the scI gene on chromosome 2 and the RFLP loci php200020 on chromosome 7 and umc 160 on chromosome 8. (agri.gov.il)
  • PPAR-γ2 was examined by genotyping for Pro12Ala using the Restriction Fragment Length Polymorphism - Polymerase Chain Reaction (PCR - RFLP). (biomedcentral.com)
  • A restriction fragment length polymorphism (RFLP) is a genetic variant that can be observed by cleaving the DNA into restriction fragments using a restriction enzyme. (pharmacy180.com)
  • Polymerase chain reaction-restriction fragment length polymorphism methods were used to genotype DRD2 Taq 1A polymorphism with genomic DNA isolated from whole blood collected at the enrollment. (fluoridealert.org)
  • Several methods have been devised recently for very sensitive detection of variola virus DNA and to distinguish this DNA from that of other orthopoxviruses, the most promising being analysis by polymerase chain reaction (PCR) of restriction fragment length polymorphisms, multiplex PCR and real-time PCR with fluorigenic probes. (who.int)
  • Materials and Methods: Associations of seven XRCC3 genotypes, namely rs1799794, rs45603942, rs861530, rs3212057, rs1799796, rs861539 and rs28903081, with the risk of asthma were investigated among 198 patients with asthma and 453 non-asthma controls by polymerase chain reaction-restriction fragment length polymorphism genotyping methodology. (iiarjournals.org)
  • Genotypes were determined by polymerase chain reaction and restriction enzyme analysis. (molvis.org)
  • Polymerase chain reaction (PCR) was conducted using groEL PCR-restriction fragment length polymorphism and sequence analysis. (who.int)
  • CYP2A13 genetic polymorphisms may be associated with interindividual differences in susceptibility to tobacco-related tumorigenesis, because the resultant variations in CYP2A13 expression and metabolic activity can significantly alter the extent of NNK metabolic activation in human lung. (aspetjournals.org)
  • Several common genetic polymorphisms in the low density lipoprotein receptor (LDL-R) gene have associated with modifications of serum total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C) levels, but the results are not consistent in different populations. (biomedcentral.com)
  • Common single nucleotide polymorphisms (SNPs) in genes involved in lipid metabolism are potentially important genetic markers in affecting normal variation in the plasma or serum lipid profiles and thus determining susceptibility or resistance to CHD in the general population. (biomedcentral.com)
  • A number of studies have investigated the relationships between treatment outcomes and individual genetic polymorphisms which will determine the efficacies and toxicities of chemotherapeutic agents, especially of 5-FU and platinum agents. (biomedcentral.com)
  • Single nucleotide polymorphism (SNP) typing for VDBP polymorphisms (SNP rs4588 and rs7041) was performed on this cohort to determine potential genetic correlations. (diabetesjournals.org)
  • A new high-density genetic linkage map was constructed by using specific locus amplified fragment sequencing technology. (frontiersin.org)
  • Polymorphism at MHC loci facilitates binding of a diversity of pathogens and this evolutionary selection pressure is thought to contribute to the high genetic variation in MHC loci [ 1 ]. (biomedcentral.com)
  • Large-scale, multicentered, controlled prospective studies are needed to further explore the effects of RAAS polymorphisms or other genetic factors on NAION susceptibility. (molvis.org)
  • A polymorphism and the somatic mutation of encoding region of C1GALT1C1 gene were not significantly related to the genetic susceptibility to IgAN in Northern Chinese population. (biomedcentral.com)
  • The genetic and genomic basis of flowering time and biomass yield in alfalfa ( Medicago sativa L.) remains poorly understood mainly due to the autopolyploid nature of the species and the lack of adequate genomic resources. (biomedcentral.com)
  • Knowledge of genetic polymorphisms that allow accurate quantification of T2DM and obesity risk will allow the development of complex models with diagnostic and prognostic. (biomedcentral.com)
  • A polymorphism can serve as a genetic marker that can be followed through families. (pharmacy180.com)
  • Genetic polymorphism. (bvsalud.org)
  • The aim of this study was to identify any impact of CYP2A13 single-nucleotide polymorphisms (SNPs) on CYP2A13 expression in human lung. (aspetjournals.org)
  • To date, more than 20 single-nucleotide polymorphisms (SNPs) have been identified in CYP2A13 (Zhang et al. (aspetjournals.org)
  • Up to now, several single-nucleotide polymorphisms (SNPs) have been identified in the APOA1 gene located on the long arm of chromosome 11 [ 16 ]. (biomedcentral.com)
  • C single nucleotide polymorphisms (SNPs). (biomedcentral.com)
  • 99%), with inter-strain diversity comprising mainly single nucleotide polymorphisms (SNPs) and minor insertions or deletions (indels). (biomedcentral.com)
  • Firstly, single nucleotide polymorphisms (SNPs) in the promoter region of C1GALT1C1 gene were screened. (biomedcentral.com)
  • Two coding single nucleotide polymorphisms (SNPs) supposedly affect their functions: GSTO1*C419A (rs4925) causing alanine to aspartate substitution (*A140D) and GSTO2*A424G (rs156697) causing asparagine to aspartate substitution (*N142D), and have been associated with several neurodegenerative diseases and cancers. (cancerindex.org)
  • The map contains 2,808 single-nucleotide polymorphism markers distributed on 20 linkage groups with a total length of 1,308.20 cM and an average inter-marker distance of 0.47 cM. (frontiersin.org)
  • Molecular data, in particular genome-wide single nucleotide polymorphism (SNP) markers, can complement historic and archaeological records to elucidate these past events. (biomedcentral.com)
  • Developed in the early 1990s by KeyGene, AFLP uses restriction enzymes to digest genomic DNA, followed by ligation of adaptors to the sticky ends of the restriction fragments. (wikipedia.org)
  • AFLP-PCR is a highly sensitive method for detecting polymorphisms in DNA. (wikipedia.org)
  • The AFLP technology has the capability to detect various polymorphisms in different genomic regions simultaneously. (wikipedia.org)
  • AFLP not only has higher reproducibility, resolution, and sensitivity at the whole genome level compared to other techniques, but it also has the capability to amplify between 50 and 100 fragments at one time. (wikipedia.org)
  • As a result, AFLP has become extremely beneficial in the study of taxa including bacteria, fungi, and plants, where much is still unknown about the genomic makeup of various organisms. (wikipedia.org)
  • As amplified fragment length polymorphism (AFLP) markers are discovered and genotyped as the samples are assayed, this type of marker is free of ascertainment bias. (biomedcentral.com)
  • Twenty two random primers with an average of 71.2% polymorphism produced 151 polymorphic bands. (scirp.org)
  • A total of 151 polymorphic loci were obtained from the enzyme-probe combinations. (cmich.edu)
  • In detail, the procedure of this technique is divided into three steps: Digestion of total cellular DNA with one or more restriction enzymes and ligation of restriction half-site specific adaptors to all restriction fragments. (wikipedia.org)
  • Interindividual differences observed in the metabolism of xenobiotics may be due to polymorphisms of genes encoding the detoxification enzymes. (springeropen.com)
  • Restriction endonucleases are bacterial enzymes that cleave double-stranded DNA (dsDNA) into smaller fragments. (pharmacy180.com)
  • Restriction enzymes form either staggered cuts (sticky ends) or blunt-end cuts on the DNA. (pharmacy180.com)
  • The -6 bp/-6 bp deletion polymorphism in the 3'UTR of TS is associated with decreased mRNA stability in vitro and lower intratumoral TS expression in vivo . (biomedcentral.com)
  • Regarding the angiotensin-converting enzyme insertion/deletion polymorphism, our findings suggest that the II genotype could be a risk factor for NAION in younger male patients when compared to all cases and controls (p=0.033, odds ratio=5.71, confidence interval=1.152¨C28.35 and p=0.03, odds ratio=5.33, confidence interval=1.17¨C24.31 respectively). (molvis.org)
  • We examined the association of the insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme gene, of the M235T polymorphism of the angiotensinogen gene, and of the A1166C polymorphism of the angiotensin II type 1 receptor gene with NAION. (molvis.org)
  • NAION occurrence was not associated with the M235T polymorphism of the angiotensinogen gene and the A1166C polymorphism of the angiotensin II, type 1 receptor gene. (molvis.org)
  • The renin-angiotensin system genes exhibit three common polymorphisms: the insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme ( ACE ) gene, the M235T polymorphism of the angiotensinogen gene ( AGT ), and the A1166C polymorphism of the angiotensin II type 1 receptor gene ( AT1-receptor ). (molvis.org)
  • No significantly positive associations were found for the CYP1A1 T3801C [ p = 0.71, OR = 1.23 (0.56-2.72)] and GSTM1 - null [ p = 0.26, OR = 1.37 (0.76-2.4)] polymorphisms and prostate cancer susceptibility. (springeropen.com)
  • The aim of this study was to investigate the association of Pro12Ala polymorphism in the PPAR-γ2 gene with susceptibility to obesity or T2DM in a Cameroonian population. (biomedcentral.com)
  • Fragment Analysis encompasses a wide variety of genotyping, DNA profiling, and mutation detection techniques for medical, environmental, and agricultural research. (macrogen-apac.com)
  • CDC also genotyped the isolates in all veillance Network adopted the standard IS 6110 fingerprinting panels, so a total of eight laboratories participated in the over- method for primary genotyping (5). (cdc.gov)
  • In Clark and Diamond (1993) study, 16 different genotypes were observed among 18 isolates of E. histolytica from diverse geographical locations using the combined results of restriction digestion of SREHP and amplification of the SSG locus. (scialert.net)
  • The human genome contains many thousands of polymorphisms (DNA sequence variations at a given locus). (pharmacy180.com)
  • Coagulase gene PCR-RFLPs exhibited 10 patterns that ranged from 1 to 8 fragments with AluI digestion. (hindawi.com)
  • they used a nested PCR of the SREHP gene coupled with restriction digestion. (scialert.net)
  • A genomic library is a collection of fragments of dsDNA obtained by digestion of the total DNA of the organism with a restriction endonuclease and subsequent ligation to an appropriate vector. (pharmacy180.com)
  • In this study, we analyzed the allele and genotype frequencies of the urotensin-II gene ( UTS2 ) polymorphisms, Thr21Met and Ser89Asn, among Turkish patients with migraine. (bjbms.org)
  • No significant differences were observed in allele and genotype frequencies for Thr21Met and Ser89Asn polymorphisms between the patients with migraine and control group. (bjbms.org)
  • It is noteworthy that no differences in genotype frequencies of the VDBP polymorphisms were associated with serum VDBP levels or between type 1 diabetic patients and control subjects. (diabetesjournals.org)
  • A number of markers are now available to detect nuclear DNA polymorphisms. (intechopen.com)
  • We analyzed the quantitative trait loci (QTL) to identify conserved genomic regions and detected molecular markers and potential candidate genes associated with the traits to improve alfalfa and provide genomic resources for the future studies. (biomedcentral.com)
  • Here we reported QTL, markers, and potential candidate genes associated with spring flowering time and biomass yield of alfalfa, which constitute valuable genomic resources for improving these traits via marker-assisted selection (MAS). (biomedcentral.com)
  • Selective amplification of some of these fragments with two PCR primers that have corresponding adaptor and restriction site specific sequences. (wikipedia.org)
  • The nucleotide sequences of Serine-Rich Entamoeba histolytica Protein (SREHP) gene have already exhibited stable and significant polymorphism in the gene studies. (scialert.net)
  • The first nucleotide sequences have been shown the stable and significant polymorphism in the Strain Specific Gene (SSG) and the Serine-Rich E. histolytica Protein (SREHP) gene. (scialert.net)
  • This selection is achieved by using primers complementary to the adaptor sequence, the restriction site sequence and a few nucleotides inside the restriction site fragments (as described in detail below). (wikipedia.org)
  • These results suggest that the T allele of the C825T polymorphism in the GNB3 gene is associated with MDD. (neurotransmitter.net)
  • The Ala allele of the common Pro12Ala polymorphism in the isoform PPAR-γ2 is at the center of many controversies because in some populations, it has been observed to be associated with T2DM or obesity but, not in others. (biomedcentral.com)
  • Dopamine receptor D2 gene polymorphism, urine fluoride, and intelligence impairment of children in China: A school-based cross-sectional study. (fluoridealert.org)
  • Serum total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C) were measured by the clinical chemistry department using commercial kits following the manufacturer instructions. (biomedcentral.com)
  • The present study was undertaken to detect the association of LDL-R gene Ava ║ polymorphism and serum lipid levels in the Guangxi Bai Ku Yao and Han populations. (biomedcentral.com)
  • The association of LDL-R gene Ava ║ polymorphism and serum lipid levels is different between the Bai Ku Yao and Han populations. (biomedcentral.com)
  • Since NAION may occur when compromised watershed microcirculation is combined with insufficient autoregulation of systematic circulation, polymorphisms of genes involved in systematic circulation, such as the RAAS genes, may be associated with NAION occurrence. (molvis.org)
  • Tick samples (3-5 ticks) were frozen and mashed by liquid nitrogen and then deoxyribonucleic acid (DNA) was extracted using the G-spin genomic DNA extraction kit (iNrRON Biotechnology Inc., Republic of Korea). (who.int)
  • We also analyzed the predictive or prognostic value of germline polymorphisms of candidate genes associated with 5-FU and oxaliplatin. (biomedcentral.com)
  • A base substitution in one or more nucleotides at a restriction site can render the site unrecognizable by a particular restriction endonuclease. (pharmacy180.com)
  • PCR amplification of this region showed DNA bands of different size and number that could be further differentiated by using restriction enzyme AluI [ 10 ]. (hindawi.com)
  • Next, we retrospectively investigated the germline APC variant status of dogs with GI epithelial tumors using genomic DNA samples extracted from archived pathological specimens (28 purebred dogs of 14 breeds and four mixed-breed dog), as well as those stored in a canine genome bank (38 dogs of 18 breeds and a mixed-breed dogs). (biomedcentral.com)
  • Genomic DNA was extracted from buccal epithelial cells. (bvsalud.org)
  • The addition of the Southern blot analysis to the AP-PCR analysis gave rise to a total of 30 DNA profiles among the 73 A. actinomycetemcomitans study strains. (upenn.edu)
  • Macrogen has accumulated experience and significant know-how in genomics, thus enabling us to provide high quality Fragment Analysis services. (macrogen-apac.com)
  • Fragment analysis is provides precise size information of your fragment (PCR product) marked by fluorescent label. (macrogen-apac.com)
  • The DNA is cleaved using a restriction endonuclease, and the pieces are separated by gel electrophoresis and are denatured and transferred (blotted) to a nitrocellulose membrane for analysis. (pharmacy180.com)
  • Total genomic DNA from 73 strains was extracted by conventional methods. (upenn.edu)
  • The current study aimed to use Coagulase gene polymorphism to identify methicillin-resistant Staphylococcus aureus (MRSA) subtypes isolated from nasal carriers in Minia governorate, Egypt, evaluate the efficiency of these methods in discriminating variable strains, and compare these subtypes with antibiotypes. (hindawi.com)
  • The aim of this study was to use coa gene polymorphism to identify MRSA subtypes isolated from nasal carriers in Minia governorate, Upper Egypt, evaluate the efficiency of these typing methods in discriminating variable strains, and compare these subtypes with antibiotypes. (hindawi.com)
  • Length Polymorphism (PCR-PIRA and RF LP) methods. (researchgate.net)
  • Polymorphisms can arise from single-base changes and from tandem repeats. (pharmacy180.com)
  • This study illustrates the importance of coupling genomic and biologic comparisons of viral strains in order to enhance understanding of viral evolution and pathogenesis. (biomedcentral.com)
  • A recently identified polymorphism of a G-protein beta3 subunit (C825T) has been shown to be associated with increased signal transduction and ion transport activity. (neurotransmitter.net)
  • Association between a G-protein beta3 subunit gene polymorphism and the symptomatology and treatment responses of major depressive disorders. (neurotransmitter.net)
  • Several polymorphisms in TS may influence TS mRNA transcription, stability, or protein expression. (biomedcentral.com)
  • This study aimed to examine the contribution of genotypes of DNA double-strand break repair gene X-ray repair cross complementing protein 3 (XRCC3) and its polymorphisms to asthma risk in the Taiwanese. (iiarjournals.org)
  • It can amplify the sequence, even when the targeted sequence makes up less than one part in a million of the total initial sample. (pharmacy180.com)
  • There was no somatic mutation detected in total 202 clones of 22 individuals. (biomedcentral.com)
  • A new mutation has been reported, making a total of 15 different mutations that can cause premature stop codons in the alpha-L-iduronidase gene ( IDUA ), and the biochemistry of these mutations has been investigated. (medscape.com)
  • The objective of the present study was to investigate the effect of two polymorphisms (-75 G/A and +83 C/T) of APOA1 on lipid profiles and the risk of CAD. (biomedcentral.com)
  • Alterations in plasma lipid and lipoprotein composition including a tendency toward an increase in total cholesterol (TC) and triglyceride (TG) and decrease in high-density lipoprotein cholesterol (HDL-C) levels suggest that psoriasis may associate with the disorders of lipid metabolism [ 25 , 26 ]. (hindawi.com)
  • Each enzyme cleaves at a specific four to eight-base pair sequence (a restriction site), producing DNA segments called restriction fragments. (pharmacy180.com)
  • The present invention provides a new enzyme which is structurally different from those previously described and which will cleave APP to generate amyloidogenic fragments the size expected of a Met.sub.596 -Asp.sub.597 cleavage. (everypatent.com)
  • Therefore, we investigated whether this Gbeta3 polymorphism is associated with affective disorders or with the response to antidepressant treatment in 88 depressive patients (10 bipolar disorder, 78 major depression) compared with 68 schizophrenic patients and 111 healthy controls. (neurotransmitter.net)
  • A total of 146 patients with migraine (14 with aura [MA group] and 132 without aura [MO group]) were genotyped for Thr21Met and Ser89Asn polymorphisms and compared with 154 age- and sex-matched healthy controls. (bjbms.org)
  • In summary, Thr21Met and Ser89Asn polymorphisms of the UTS2 gene are not risk factors for migraine in our sample of Turkish migraine patients. (bjbms.org)
  • Patients with APOE ε 4 had significantly higher levels of total cholesterol and LDL cholesterol, whereas those with the ε 2 had higher HDL cholesterol, and triglycerides. (hindawi.com)
  • Genomic DNA from the patients' peripheral blood mononuclear cells was extracted. (biomedcentral.com)
  • Eight patients received conditioning with fludarabine and low-dose total body irradiation followed by hematopoietic cell transplantation from an HLA-matched sibling donor. (aacrjournals.org)
  • Treatment of metastatic renal cell carcinoma with allogeneic hematopoietic cell transplantation after nonmyeloablative conditioning with fludarabine/total body irradiation is feasible and may induce tumor regression or stabilization in some patients. (aacrjournals.org)
  • Furthermore, no statistically significant differences between the studied polymorphisms and tumor parameters (the Gleason score and clinical stages of aggressiveness) at diagnosis of PCa. (springeropen.com)
  • Functional relevance of yet another GSTO2 polymorphism, identified at the 5' untranslated (5'UTR) gene region (GSTO2*A183G, rs2297235), has not been clearly discerned so far. (cancerindex.org)
  • The zebra finch MHC includes multiple Class I and Class II genes, some of which appear to be pseudogenes, and spans a much more extensive genomic region than the chicken MHC, as evidenced by the presence of MHC genes on each of seven BACs spanning 739 kb. (biomedcentral.com)
  • The CYP1A1 3801T/C (also named MspI polymorphism, *2A or m1), results from a replacement of thymine by a cytosine at the 3801st base pair in the 3' flanking region of the gene [ 9 , 10 ]. (springeropen.com)
  • Our results show that one out of 60 bulls tested exhibited polymorphism (G→T) at position 559 in exon 4 of SLC35A3 gene. (researchgate.net)
  • In either case, cleavage with the endonuclease results in fragments of lengths differing from the normal that can be detected by DNA hybridization. (pharmacy180.com)
  • Genomic polymorphism can influence drug transport, metabolism and cellular response, and lead to individual variations in terms of the response and toxicity and even to overall survival [ 8 , 9 ]. (biomedcentral.com)
  • Previous studies have noted a specific association between type 1 diabetes and insufficient levels of vitamin D, as well as polymorphisms within genes related to vitamin D pathways. (diabetesjournals.org)
  • The probe was labeled with digoxigenin, and hybridized fragments were detected with anti-digoxigenin antibody. (upenn.edu)
  • The fragment of interest is detected using a probe. (pharmacy180.com)
  • Unlike some other forages, harvesting before reaching the full seed stage is common in alfalfa for high total digestible nutrients (TDN) which decreases with maturity stage. (biomedcentral.com)
  • In addition, 2 common synonymous coding single-nucleotide polymorphisms are found and genotyped in samples from 4 ethnic groups. (medscape.com)
  • The membrane was probed with a previously characterized 5.2 kilobases (kb) DNA fragment cloned from A. actinomycetemcomitans strain Y4. (upenn.edu)
  • A total of 323 children (2014-2015, 7-12 years old) were enrolled from four schools in both historical endemic and non-endemic areas of fluorosis in Tianjin of China using a cluster sampling method. (fluoridealert.org)
  • A total of 1024 subjects of Bai Ku Yao and 792 participants of Han Chinese were randomly selected from our previous stratified randomized cluster samples. (biomedcentral.com)
  • Concomitance of Polymorphisms in Glutathione Transferase Omega Genes Is Associated with Risk of Clear Cell Renal Cell Carcinoma. (cancerindex.org)
  • DNA was isolated from young leaves using HiPurA™ Plant genomic DNA Miniprep Purification spin kit (Himedia Laroratories Pvt. (scirp.org)
  • A total of 39 QTLs for growth habit-related traits was detected on 10 chromosomes explaining 4.55-27.74% of the phenotypic variance, in which 6 QTLs were for lateral branch angle, 8 QTLs were for extent radius, 7 QTLs were for the index of plant type, 11 QTLs were for main stem height, and 7 QTLs were for lateral branch length. (frontiersin.org)
  • DRD2 Taq 1A polymorphism was not related to IQ in children exposed to high fluoride. (fluoridealert.org)
  • In overall participants, the DRD2 Taq 1A polymorphism itself was not related to IQ scores in children who had a high level of urine fluoride. (fluoridealert.org)
  • Due to its high polymorphism and importance for disease resistance, the major histocompatibility complex (MHC) has been an important focus of many vertebrate genome projects. (biomedcentral.com)
  • The PCR was performed in a reaction volume of 25 µl containing 10 mM Tris-HCl, pH 9.0, 2 mM MgCl 2 , 50 mM KCl, 0.01% gelatin, 200 µM of each dNTP, 4 µM of primer, 1 Units of Taq DNA polymerase (Bangalore Genei, Bangalore, India) and 30 ng of genomic DNA. (scirp.org)
  • health concern in more than 70 coun- David Ltd, India) are the first line of A total of 188 parasitologically new tries across the world. (who.int)
  • The pathophysiology of migraine is complex, and a number of genomic regions have been associated with the development of migraine. (bjbms.org)
  • Three TOF related QTL were stable and four TOF QTL were detected in the corresponding genomic locations of the flowering QTL of M. truncatula , an indication of possible evolutionarily conserved regions. (biomedcentral.com)
  • A total number of 300 subjects with CAD and 300 age and sex matched healthy controls were enrolled for the study. (biomedcentral.com)
  • A total number of 300 subjects with CAD and 300 age and sex matched healthy controls were enrolled for the study between July 2011 and June 2014 in the Second Clinical Medical College of Jinan University, China. (biomedcentral.com)
  • We explored the association of the PPAR-gamma2 (peroxisome proliferator-activated receptor) Pro-12-Ala polymorphism with endometriosis in a case-control study with 51 women with endometriosis stages I-IV and 55 control women without endometriosis. (endometriosi.it)
  • A total of 400 specimens were collected from nasal carriers in Minia governorate, Egypt, between March 2012 and April 2013. (hindawi.com)
  • A total of 400 specimens were collected from anterior nares of Egyptian carriers: two hundred from rural residents who are in contact with animals and 200 specimens from urban residents, between March 2012 and April 2013. (hindawi.com)
  • Normal cleavage of APP occurs within the A4 region, indicating that an alternate cleavage event occurs when the normal full length is generated. (everypatent.com)