DNA Topoisomerase IVDNA Topoisomerases, Type IITopoisomerase II InhibitorsDNA GyraseDNA Topoisomerases, Type ITopoisomerase I InhibitorsAnti-Infective AgentsFluoroquinolonesCiprofloxacinTeniposideAmsacrineDNA, SuperhelicalMacromolecular SubstancesTopoisomerase InhibitorsMolecular Sequence DataDrug Resistance, MicrobialNovobiocinElectrophoresis, Polyacrylamide GelMolecular WeightQuinolonesAmino Acid SequenceEtoposideDNA, CatenatedCamptothecinPhotosynthetic Reaction Center Complex ProteinsDNARazoxaneEllipticinesNorfloxacinPeptidesBase SequenceEscherichia coli4-QuinolonesMutationIntercalating AgentsNaphthyridinesPodophyllotoxinAntigens, NeoplasmAminocoumarinsDNA DamageDNA-Binding ProteinsPlasmidsDNA CleavageEnzyme InhibitorsDNA TopoisomerasesProtein SubunitsNucleic Acid ConformationCloning, MolecularAminoacridinesThiobarbituratesAntineoplastic Agents, PhytogenicStreptococcus pneumoniaeDrug Resistance, BacterialKineticsAntineoplastic AgentsCatalysisDrug ResistanceMicrobial Sensitivity TestsDNA, KinetoplastDNA ReplicationSaccharomyces cerevisiaeDNA, BacterialCoumarinsOfloxacinMycoplasma hominisTumor Cells, CulturedIsoenzymesTopotecanSubstrate SpecificityBinding SitesCrithidia fasciculataStaphylococcus aureusRecombinant ProteinsGenes, BacterialCell LineStructure-Activity RelationshipMitoxantroneHeLa CellsSequence Homology, Amino AcidModels, MolecularCell NucleusLeukemia P388Adenosine TriphosphateLevofloxacinAdenosine TriphosphatasesCell CycleAnti-Bacterial AgentsDoxorubicinProtein ConformationBacterial ProteinsDNA, NeoplasmProtein BindingAclarubicinMitosisDrug Screening Assays, AntitumorChromosome SegregationDNA, CircularAdenylyl ImidodiphosphateCricetinaeLeukemia L1210