The PBAC recommended listing in the General and Optometrical Schedules on a cost-minimisation basis against the individual components given concurrently and against the combination product dorzolamide 2 % (base) with timolol 0.5 % (base) eye drops (Cosopt). (pbs.gov.au)
He thus laid the groundwork for the development of topical glaucoma medications including Trusopt® (dorzolamide), and Cosopt ® (dorzolamide hydrochloride-timolol maleate). (ufl.edu)
The combination of dorzolamide and timolol is used to treat eye conditions, including glaucoma and ocular hypertension, in which increased pressure can lead to a gradual loss of vision. (optionrx.com)
Dorzolamide and timolol is used for patients whose eye condition has not responded to another medication. (optionrx.com)
Dorzolamide is in a class of medications called topical carbonic anhydrase inhibitors. (optionrx.com)
Dorzolamide and timolol lowers pressure in the eye by decreasing the production of natural fluids in the eye. (optionrx.com)
Dorzolamide/timolol maleate is a medication used to reduce high pressure in the eye due to glaucoma or ocular hypertension. (optionrx.com)
This drug contains a beta blocker (timolol) and a carbonic anhydrase inhibitor (dorzolamide). (optionrx.com)
Dorzolamide/timolol maleate works by reducing the fluid in your eye. (optionrx.com)
Dorzolamide/timolol maleate is a generic medication also sold under the brand name Cosopt. (optionrx.com)
For the treatment of high eye pressure, dorzolamide/timolol maleate use is common. (optionrx.com)
What Form(s) Does Dorzolamide Hcl-Timolol Mal Come In? (optionrx.com)
40509154 bids are invited for echs re 102 dorzolamide 2 percent plus timolol 0 point 5 percent eye drops, 5ml , eye drops bimatoprost 0 point 03 percent plus timolol 0.5 percent 2.5 ml , moxifloxacin 0.5percent eye oint 5 gm , eye pad sterile , vicryl 6per 0 sutures pkt of 12 foil , brimonidine 0.1 plus timolol 0.5 percent eye drops, bak free , preservative free or purite oxychlorocomplex based preservative. (punjabtenders.net)
Thus, she started dorzolamide 2%/timolol maleate 0.5% fixed combination (Cosopt, Merck & Co Inc). No other abnormal findings were observed on slit-lamp examination. (ekjo.org)
Administration of timolol maleate1
the IOP-lowering of brimonidine tartrate and timolol maleate ophthalmic solution dosed twice a day was slightly less than that seen with the concomitant administration of timolol maleate ophthalmic solution, 0.5% dosed twice a day and brimonidine tartrate ophthalmic solution, 0.2% dosed three times per day. (nih.gov)
Combigan1
It is also the active ingredient of Combigan along with timolol maleate . (irosacea.org)
Ophthalmic solution2
These highlights do not include all the information needed to use BRIMONIDINE TARTRATE and TIMOLOL MALEATE OPHTHALMIC SOLUTION safely and effectively. (nih.gov)
The recommended dose is one drop of brimonidine tartrate and timolol maleate ophthalmic solution in the affected eye(s) twice daily approximately 12 hours apart. (nih.gov)
0.251
Prior to the onset of symptoms, the patient hadexperienced right-sided epistaxis that was treated in an emergency departmentwith intranasal 0.25% phenylephrine hydrochloride, topical tetracaine, silvernitrate cautery, and nasal packing. (jamanetwork.com)
Dynamic Gd-MRI was applied to examine the signal enhancement in AC and vitreous body upon microbead-induced ocular hypertension and unilateral topical applications of latanoprost, timolol maleate, and brimonidine tartrate to healthy eyes. (nyu.edu)
When IOP cannot be controlled with topical drops and IOP is high enough to cause optic nerve damage in a short period of time, osmotic diuretics are indicated. (medscape.com)
The PBAC recommended a restriction wording of "elevated intra-ocular pressure in a patient with open angle glaucoma/ocular hypertension not adequately controlled with monotherapy" be applied to all restricted benefit listings of combination eye drops containing an alpha-agonist with timolol, a carbonic anhydrase inhibitor with timolol or a prostaglandin/prostamide analogue with timolol. (pbs.gov.au)
Restricted benefit listing in the General and Optometrical Schedules for reduction of elevated intra-ocular pressure in patients with either open-angle glaucoma or ocular hypertension who are not adequately controlled with timolol 5 mg/mL eye drops. (pbs.gov.au)
Flarex is a glucocorticosteroid for topical application in the form of eye drops. (healthylifemeds.com)
Latanoprost2
Opposite trends were observed in latanoprost- and timolol-treated eyes, indicative of their respective drug actions on increased uveoscleral outflow and reduced AH production. (nyu.edu)
[ 18 , 19 ] A systematic review and meta-analysis of 15 randomized clinical trials studying IOP-lowering agents for treatment of normal-tension glaucoma determined that latanoprost, bimatoprost, and timolol were most effective. (medscape.com)
Systemic5
Timolol can be recommended as an alternative to systemic β-blockers and watchful waiting for many patients. (johnshopkins.edu)
These findings drew attention to the systemic effects of topical hypotensive drug treatment. (nyu.edu)
Even smaller hemangiomas can cause refractive errors or amblyopia, and oftentimes need to be treated with either systemic or topical therapy depending on the size and extent," she said. (medscape.com)
Timolol (systemic): Bradycardia, hypotension, bronchospasm and cardiac arrest. (azurewebsites.net)
Timolol, a non-selective adrenergic receptor antagonist, reduces IOP by decreasing the production of aqueous humour in the ciliary epithelium. (azurewebsites.net)
Levobunolol1
Nonselective beta-blockers (eg, timolol maleate, levobunolol) are controversial because as visual-field progression is possibly due to secondary aggravated nocturnal arterial hypotension. (medscape.com)
Prostaglandin1
In patients who do not adequately respond to topical β-blockers or prostaglandin analogues: Instil 1 drop into the affected eye(s) once daily. (azurewebsites.net)
Glaucoma2
He is perhaps best known for this groundbreaking research on topical glaucoma medications, which preserve the sight of millions. (ufl.edu)
Under the impression of secondary glaucoma associated with uveitis, she was treated with additional oral acetazolamide, topical prednisolone acetate 1% (Prednilone, Daewoo Pharm), brimonidine 0.15% (Alphagan-P, Allergan Inc) and intravenous mannitol injection. (ekjo.org)
Beta blocker1
Timolol is a beta-blocker that also reduces pressure inside the eye. (healthylifemeds.com)
Concomitantly1
Used concomitantly with other topical ophthalmic drug products to lower IOP. (medscape.com)
Medications1
Timolol is in a class of medications called topical beta blockers. (optionrx.com)
Lidocaine2
lignocaine or lidocaine hcl 0.02 (2%) 30 ml 30 ml 2 topical lignocaine 30 gm jelly anaesthetics oint lignocaine or lidocaine hcl ointment / jelly 30 gm 30 gm 3 topical lignocaine 10 gm jelly anaesthetics oint lignocaine or lidocaine hcl 10 gm 10 gm 4 topical lignocaine solution 4% anaesthetics lignocaine 4% topical solution 30 ml 30 ml 5 lignocaine with adrenaline inj. (tendersinmaharashtra.com)
A topical local anesthetic preparation that is composed of a mixture of lidocaine and prilocaine. (bvsalud.org)
Oral2
BACKGROUND: There has been a dramatic increase in the off-label use of ophthalmic timolol maleate, a β-blocker used for infantile hemangioma (IH) treatment as a topical counterpart to oral propranolol. (johnshopkins.edu)
Timolol: May have additive effects resulting in hypotension and/or notable bradycardia with oral Ca channel blockers, guanethidine, antiarrhythmics (e.g. amiodarone), digitalis glycosides, parasympathomimetics, narcotics and MAOIs. (azurewebsites.net)
Solution1
A simple, rapid, precise, and reproducible RP-HPLC method development and validation for estimation of Diclofenac Diethylamine in Topical Solution. (ijpsnonline.com)
CONCLUSIONS: Timolol seems to be a well-tolerated, safe treatment option with moderate to good effectiveness, demonstrating best response in thin, superficial IHs regardless of pretreatment size. (johnshopkins.edu)
Patients3
METHODS: A multicenter retrospective cohort study of 731 patients treated with topical timolol was completed at 9 centers. (johnshopkins.edu)
72 patients were included in this randomized control trial and were either treated with PRP or topical minoxidil. (bvsalud.org)
These results have the opportunity to improve patient compliance and overall satisfaction while offering an improved option in patients unsatisfied with topical minoxidil. (bvsalud.org)
Treatment1
Philip J. Jun X. Systematic review of topical diclofenac for the treatment of acute and chronic musculoskeletal pain. (ijpsnonline.com)
Pressure1
It contains two different medicines (brimonidine and timolol) that both reduce high pressure in the eye. (assetpharmacy.com)
Application1
In 2013, the FDA approved topical application of brimonidine 0.33% ( Mirvaso - requires subscription to view post) for facial erythema or rosacea. (irosacea.org)
Treat1
Bactroban topical (for use on the skin) is used to treat skin infections such as impetigo or a "Staph" infection of the skin. (freerxacc.com)