Topical atropine. Medical search. Frequent questions

Topical therapy is an alternative noninvasive treatment for DME that has become a more desirable option for patients in recent years, though the efficacy of these ophthalmic solutions is still under investigation. (reviewofoptometry.com)
The data from this trial shows that, compared with topical steroids, treatment with ophthalmic NSAIDs may offer more stable IOP levels and potentially reduce CST in DME patients with good glycemic control. (reviewofoptometry.com)
Atropine Sulfate is a sterile topical anticholinergic for ophthalmic use. (dkshdiscover.com)

All had documented uveitis, and all improved with topical application of 1% atropine and steroids. (medscape.com)
Topical steroids increased IOP in DME patients after eight and 12 weeks of treatment, while those treated with an NSAID demonstrated stable levels. (reviewofoptometry.com)
Topical steroids may be used, but they may be less effective. (health-care-clinic.org)
Frequent topical steroids (eg. (iritis.co.uk)
Treatment - depends on cause: topical steroids or NSAIDs, topical atropine, fenbendazole. (vetacademy.org)
For skin lesions, soothing lotions such as calamine lotion, topical steroids and/oral antihistamines may relive itching. (who.int)

Evaluation of the Levels of Low-dose Topical Atropine (0.01%) in Aqueous and Vitreous Humor in Human Eyes. (bvsalud.org)
This is the first human study that confirmed penetration of 0.01% topical atropine in aqueous and vitreous humor in live human eyes . (bvsalud.org)
The purpose of this study was to evaluate penetration of low- dose atropine 0.01% in aqueous and vitreous humor . (bvsalud.org)
One drop of 0.01% atropine was put in the eye to be operated. (bvsalud.org)
Measurable concentration of low- dose topical atropine (0.01%) was noted in aqueous and vitreous humor after instillation of a single drop of low- dose atropine . (bvsalud.org)
Children who took short-term topical atropine eye drops, 0.01% to 1.0%, had no difference in final refractive errors 10 to 20 years after treatment. (ajmc.com)
Among all the strategies assessed to date, atropine was considered the most effective, and presently, low dose atropine (0.01 percent) is widely used to slow myopia. (reviewofmm.com)
14 In more recent studies, administration of 1 percent and even 0.01 percent atropine resulted in an increased sub and para-foveal choroidal thickness. (reviewofmm.com)

However, a recent study suggests that dogs and even cats with large corneal lacerations and concurrent lens capsule ruptures can be successfully managed with medical therapy that includes topical and systemic broad-spectrum antibiotics, a topical mydriatic (eg, atropine), and systemic corticosteroid or NSAID. (merckvetmanual.com)
Besides local effects on the eye, atropine has systemic effects on multiple organs in the body. (slu.se)
Treatment is with topical or systemic antiviral drugs. (msdmanuals.com)

Atropine is a nonselective muscarinic antagonist, i.e., it competes for binding sites on all muscarinic receptors, thus blocking the action of acetylcholine. (reviewofmm.com)
By blocking the action of acetylcholine at muscarinic receptors, atropine also serves as an antidote for poisoning by organophosphate insecticides and nerve gases. (the-medical-dictionary.com)

This indicates that the effect of atropine on bowel motility is low at this dose (0,009 mg/kg). (slu.se)

The patient was admitted to the hospital and was administered hourly topical treatments of polyhexamethylene biguanide eye drops, hexamidine, and 1% atropine. (cdc.gov)
Prescribe atropine eye drops. (crstodayeurope.com)
Once irrigated, eye lesions should be treated by applying petroleum jelly on follicular margins to prevent sticking, and the use of cyclopegic eye drops, such as atropine or homatropine to prevent adhesion of the iris to the cornea. (who.int)
INTRODUCTION: Topical atropine eye drops at low concentrations have been shown to slow myopia progression in East Asian studies. (omeka.net)

Atropine works by competitively occupying muscarinic receptor sites, thus reducing the effects of excessive acetylcholine on these sites brought about by cholinesterase inhibition. (cdc.gov)
The main action of the parasympathetic nervous system is to stimulate the M2 muscarinic receptor in the heart, but atropine inhibits this action. (the-medical-dictionary.com)

A subtherapeutic dose of anticholinergic atropine sulfate is added to discourage overdosage, in which case diphenoxylate may clinically mimic the effects of codeine. (medscape.com)
Each tab of Lomotil (or 5 cc of elixir) contains 2.5 mg diphenoxylate hydrochloride and 0.025 mg atropine sulfate. (medscape.com)

Because ciliary muscles of reptiles are composed of striated muscle rather than smooth muscle fibers, conventional mydriatic agents (parasympatholytics) such as tropicamide and atropine are ineffective in producing pupillary dilation. (vin.com)
Topical atropine is used as a cycloplegic, to temporarily paralyze accommodation, and as a mydriatic, to dilate the pupils. (the-medical-dictionary.com)
Atropine degrades slowly, typically wearing off in 2 to 3 days, so tropicamide is generally preferred as a mydriatic. (the-medical-dictionary.com)

Muscarinic receptors located in the posterior segment such as the choroid and retina could be the possible site of action of low- dose atropine in myopia . (bvsalud.org)
It has been suggested that when these physiological changes do not occur with this dose (sometimes referred to as an atropine challenge ), this is indicative of cholinesterase inhibitor toxicity. (cdc.gov)
The effects of an intravenous infusion of atropine at the dose of 0,009 mg/kg have been evaluated by monitoring the intestinal motility of the horses, by means of auscultation and transcutaneous ultrasound. (slu.se)

This structure appears impervious to topical medications, thus making treatment of the globe difficult. (vin.com)
Some topical medications may be suggested to help treat the condition. (wikipedia.org)
The immunosuppressant cyclosporine (ciclosporin) may be recommended to increase tear production and, for short term use, topical corticosteroid medications are also sometimes helpful to reduce inflammation. (wikipedia.org)
Treatments to slow or stop the progression of nearsightedness include topical medications called atropine. (autonomous.ai)
Continued research is being done on atropine and other topical medications to determine if this is a worthwhile treatment option. (brighteyesfamilyvision.com)

There have been recent studies showing that using diluted atropine can slow the progression of myopia. (brighteyesfamilyvision.com)

Atropine is an important part of the treatment of uveitis in horses. (slu.se)

In addition , the ophthalmologist may ind uce mydriasis , using topical atropine in order to examine inner eye. (blogspot.com)
In atropine-induced mydriasis, the mechanism of action involves blocking the contraction of the circular pupillary sphincter muscle (which is normally stimulated by acetylcholine release), thereby allowing the radial pupillary dilator muscle to contract and dilate the pupil. (the-medical-dictionary.com)

Antidiarrheal agents (loperamide, atropine [Lomotil], and tincture of opium) should be used only in patients with mild symptoms, not in those with the acute phase of this illness. (health-care-clinic.org)

4. Pretreatment (30 min) with the non-selective muscarinic antagonists scopolamine (0.1, 0.3 or 1 mg kg(-1), i.p.) and atropine (0.3, 1 or 3 mg kg(-1), s.c.) but not methylatropine (1, 3 or 10 mg kg(-1), s.c) significantly inhibited stretching induced by Ro 04-6790 (30 mg kg(-1), i.p.). 5. (lookformedical.com)

Automatic injectors: the U.S. Armed Forces uses autoinjectors, containing 2 mg of atropine. (cdc.gov)
These atropine autoinjectors are packaged with a 2-PAM autoinjector, called Mark I kits. (cdc.gov)
Troops who are likely to be attacked with chemical weapons often carry autoinjectors with atropine and obidoxime which can be quickly injected into the thigh. (the-medical-dictionary.com)

Mechanism by which atropine counters the effects of the cholinergic toxidrome. (cdc.gov)
Despite common use, 3 the mechanism underlying the efficacy of atropine in slowing eye growth remains unclear. (reviewofmm.com)
The aim of this review is to discuss the various hypotheses for the proposed mechanism of action for atropine and present a summary of some of the studies that have been considered so far. (reviewofmm.com)
Two experiments investigated the mechanism for changes in measures of behavioral arousal inhibition in rats following administration of atropine. (the-medical-dictionary.com)

If miosis (pupillary constriction) is due to direct conjunctival vapor exposure, it is relatively unresponsive to parenteral atropine. (cdc.gov)
Interestingly, pollen shell-stimulated GAP formation was not suppressed by topical atropine, suggesting that the conjunctival GAPs and intestinal GAPs are differentially regulated. (jci.org)

These latter effects are due to the fact that atropine is able to cross the blood-brain barrier. (the-medical-dictionary.com)

benzoyl peroxide, dapsone topical. (medscape.com)
Monitor Closely (1) benzoyl peroxide, dapsone topical. (medscape.com)

Patients who fail to respond adequately to topical anti-inflammatory drugs may benefit from a course of corticosteroid therapy. (medscape.com)

Type of cholinesterase inhibitor toxicity that may require extremely high doses of atropine. (cdc.gov)
It is well known that atropine at frequent topical administrations and high doses intravenously may be a contributing factor to ileus and colic, a potentially life-threatening condition in horses. (slu.se)

Atropine is a tropane alkaloid extracted from the deadly nightshade ( Atropa belladonna ) and other plants of the family Solanaceae. (the-medical-dictionary.com)

8 Although atropine was toxic to the scleral chondrocytes at high concentrations, the finding of a reduction of synthesis of glycosaminoglycans opens up another pathway via which atropine may be exerting its effects. (reviewofmm.com)

Blepharospasm may complicate the examination procedure but a topical analgesic agent usually allows adequate examination of the cornea. (vin.com)
If necessary a topical analgesic can be used to aid decontamination. (who.int)

Although atropine is no longer in common use in ophthalmology because of its long duration of action, some surgeons prescribe topical use of this cycloplegic agent for 2 to 3 days prior to surgery for patients with known intake of alpha-blockers. (crstodayeurope.com)

There is also a view that sclera is the target site for myopia inhibition with atropine. (reviewofmm.com)

In addition to topical or infiltrative anesthesia, intravenous sedation may be required for children or any patient who is unable to cooperate. (medscape.com)

For anterior chamber taps, a 30-gauge needle on a tuberculin syringe is used to obtain a 0.1-mL sample under topical anesthesia through the limbus. (medscape.com)
Depending on the indication, satisfactory nasal anesthesia may be obtained by the use of topical sprays and pledgets, local injections, regional nerve blocks, or a combination of these. (medscape.com)

Parenteral atropine is not generally recommended for those whose sole manifestation of toxicity is miosis (pupillary constriction). (cdc.gov)

Injections of atropine are used in the treatment of bradycardia (an extremely low heart rate) and asystole, which is a condition of pulseless electrical activity (PEA) in cardiac arrest. (the-medical-dictionary.com)

A number of authors have recommended the "atropine challenge" as an aid to diagnosis. (cdc.gov)

This inducible, rapid GAP formation and antigen acquisition were suppressed by topical lidocaine or trigeminal nerve ablation, indicating that the sensory nervous system plays an essential role. (jci.org)
however, contrary to expectations, ablation of the amacrine cells did not prevent atropine from inhibiting axial elongation. (reviewofmm.com)

Instead, all three cases had bradycardia that failed to respond to atropine or (in one case) pacing before arrest. (medscape.com)

The data showed that DME patients treated with the NSAID experienced no increase in IOP over 12 weeks, while those who received the topical steroid showed a significant increase at eight and 12 weeks of treatment. (reviewofoptometry.com)
Each patient received topical atropine (1%) and timolol (0.5%), and immediate ALPI as initial treatment. (qxmd.com)
Although atropine is a dilating drop, the diluted version has minimal side effects, but the long term efficacy of this treatment is unknown. (brighteyesfamilyvision.com)

This occurs because atropine is a competitive inhibitor of the muscarinic acetylcholine receptors. (the-medical-dictionary.com)

Both the loss of balance and dry mouth that you describe are potential side effects of atropine administration. (vetinfo.com)

Medical therapies include topical atropine, topical retinoids, and oral tranilast. (wikipedia.org)

Preferred routes of administration of atropine. (cdc.gov)
2001) (Although, it does respond to topical administration). (cdc.gov)

Patients with disease primarily affecting the rectum or rectosigmoid should be managed with topical agents such as mesalamine. (health-care-clinic.org)
Atropine is contraindicated in patients predisposed to narrow angle glaucoma. (the-medical-dictionary.com)

He also reported that not using of any topical application of medication or exposure to dyes. (madridge.org)

Clinical findings against which to titrate atropine dosage. (cdc.gov)

Science Of Him Keep Going Lidocaine Topical Spray is a local anesthetic used to temporarily numb certain areas of the body. (galliumpharma.com)

8,9 Atropine was found to increase the release of dopamine but reduced the electroretinogram (ERG) b and d waves and dampened oscillations of retinal pigment epithelium (RPE) potentials. (reviewofmm.com)
15,16 Furthermore, atropine was found to inhibit choroidal thinning induced by hyperopic defocus. (reviewofmm.com)

Anatomy14

Organisms3

Diseases2

Chemicals and Drugs64

Analytical, Diagnostic and Therapeutic Techniques and Equipment6

Psychiatry and Psychology1

Phenomena and Processes10

Ophthalmic3

Steroids6

0.018

Systemic3

Blocking the action of acetylcholine2

Effect of atropine1

Drops4

Muscarinic receptor2

Sulfate2

Mydriatic3

Dose3

Medications5

Progression1

Uveitis1

Mydriasis2

Lomotil1

Scopolamine1

Autoinjectors3

Mechanism4

Conjunctival2

Cross the blood-brain b1

Dapsone topical2

Drugs1

High doses2

SOLANACEAE1

Concentrations1

Analgesic2

Cycloplegic1

Inhibition1

Intravenous1

Anesthesia2

Pupillary1

Injections1

Diagnosis1

Ablation2

Bradycardia1

Treatment3

Occurs1

Effects1

Medical1

Administration2

Patients2

Exposure1

Clinical1

Temporarily1

Found2