• Human CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. (transcriptionfactor.org)
  • CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NF-kappa-B. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. (transcriptionfactor.org)
  • CD30/TNFRSF8 is a type I transmembrane glycoprotein belonging to the TNF receptor superfamily. (bio-techne.com)
  • CD30 is a transmembrane glycoprotein receptor of the tumor necrosis factor receptor super family 8 (TNFRSF8), mediating its effects through a number of signaling pathways that produce a survival advantage to the cells on which the protein is overexpressed. (aad.org)
  • Adcetris is formulated by the conjugation of brentuximab, an anti-CD30 (also known as TNFRSF8) monoclonal antibody with payload monomethyl auristatin E (MMAE) via a cleavable peptide linker. (adcreview.com)
  • Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8) were tested 20 times on one plate, respectively. (biomatik.com)
  • Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8) were tested on 3 different plates, 8 replicates in each plate. (biomatik.com)
  • This assay has high sensitivity and excellent specificity for detection of Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8). (biomatik.com)
  • No significant cross-reactivity or interference between Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8) and analogues was observed. (biomatik.com)
  • TNFRSF8 gene expression in the OLP group (7.46 ± 1.51) was significantly higher than the Normal group (2.90 ± 1.61), but no significant difference was found between the OLP and Non-OLP groups. (nih.gov)
  • 54 disease terms (MeSH) has been reported with TNFRSF8 gene. (cdc.gov)
  • TNFRSF8 is the most frequent gene inclusion criterion for indolent T-cell lymphoproliferative disorder of the gastrointestinal tract clinical trials [ 3 ]. (mycancergenome.org)
  • Human recombinant protein fragment corresponding to amino acids 19-379 of human TNFRSF8 (NP_001234) produced in E.coli. (origene.com)
  • The mRNA expression of IL12RB2 and TNFRSF8 in FFPE OLP samples (OLP group, n = 38) were investigated with quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR) analysis and compared to those of chronic non-specific mucositis (Non-OLP group, n = 25) and normal mucosa (Normal group, n = 18). (nih.gov)
  • Predictive modeling of the expression of IL12RB2 and TNFRSF8 was constructed using support vector machine (SVM), random forest (RF), linear discriminant analysis (LDA), neural network (NN) and naive Bayes (NB) methods. (nih.gov)