In fact, and differently from mammalian species, mitochondria from Drosophila melanogaster tissues are characterized by low amounts of SCs, despite the high metabolic demands and MRC activity shown by these mitochondria. (bvsalud.org)
In brain tissue, myelin (white matter) has the highest amounts. (gerli.com)
Human1
This is the first report of these phospholipids in human tissue. (gerli.com)
Cardiolipin4
Biochemical abnormalities include decreased levels of the mitochondrial phospholipid cardiolipin, increased levels of monolysocardiolipin, and a lower degree of unsaturation of the (monolyso)cardiolipin acyl chains. (nih.gov)
Because a validated confirmatory method is not yet available, we set up and validated a high-performance liquid chromatography-mass spectrometry (HPLC-MS) method for BTHS in cultured fibroblasts, lymphocytes, and skeletal muscle based on cardiolipin, monolysocardiolipin, and the monolysocardiolipin/cardiolipin ratio. (nih.gov)
In addition, for unknown reasons, a variant of cardiolipin called monolysocardiolipin (MLCL) is formed. (medlineplus.gov)
The diagnosis of Barth syndrome is established in a male proband with either an increased monolysocardiolipin:cardiolipin ratio (if available) or a hemizygous pathogenic variant in TAFAZZIN (formerly TAZ ) identified by molecular genetic testing . (nih.gov)
Found2
Most isoforms are found in all tissues, but some are found only in certain types of cells. (wikipedia.org)
We found that TBI results in significantly decreased content of CL in small intestine, bone marrow (5.3- and 2.4-times, respectively) compared to lung and brain tissues. (cdc.gov)