• But it is perhaps not auspicious to quote him for purposes of the scientific debates on human cloning, because Ramsey agreed with and supported the scientific myth of the "pre-embryo" 47 made famous by Jesuit Richard McCormick and frog embryologist Clifford Grobstein. (lifeissues.net)
  • Perhaps Ramsey would give other extraordinarily powerful arguments as to why human cloning is unethical, but he obviously would not be able to base it on his unscientific "pre-embryo" position. (lifeissues.net)
  • Otherwise, such a treaty would not recognize the inherent human nature of the early human embryo or fetus until after birth , and thus cloning them and using them for research - both "therapeutic" and "reproductive" -- would not be banned, and women undergoing "infertility treatments" could surely be put in danger. (lifeissues.net)
  • Again, Saunders is referring to SCNT as "THE" cloning procedure, when there are many other ways to clone a human being as well, and he is scientifically mis-defining the product of SCNT (i.e., the cloned human embryo). (lifeissues.net)
  • … "embryo" means a human organism during the first 56 days of its development following fertilization or creation, excluding any time during which its development has been suspended, and includes any cell derived from such an organism that is used for the purpose of creating a human being. (hinxtongroup.org)
  • … "human clone" means an embryo that, as a result of the manipulation of human reproductive material or an in vitro embryo, contains a diploid set of chromosomes obtained from a single - living or deceased - human being, fetus, or embryo. (hinxtongroup.org)
  • The resulting embryo was then used to create embryonic stem cells, capable of generating every cell type in the body, and the nuclei of these cells were injected into other eggs to produce clones. (newscientist.com)
  • In fact to get a embryonic stem cell a human embryo has to be disassembled. (ipl.org)
  • People who believe that an embryo should not be destroyed tend to say that embryonic stem cell research should not be conducted. (ipl.org)
  • Dr. Shinya Yamanaka of Japan and others have turned adult skin cells into human embryonic stem cells, without using an embryo. (nationalrighttolifenews.org)
  • ESCs are immortal, but develop into normal tissues, including germ cells, after injection into an early embryo. (jax.org)
  • It is also our view that there are no sound reasons for treating the early-stage human embryo or cloned human embryo as anything special, or as having moral status greater than human somatic cells in tissue culture. (wikiquote.org)
  • A view of how an animal embryo is specified to develop and differentiate into a wide spectrum of cell types, and how the spatial patterns and axes of embyros are determined. (upenn.edu)
  • They instead refer to the embryo as a "clump of cells" or as "potential human life," Somerville says, "despite the fact that they are, given the right conditions, human life with the potential to go on living for years and years, just like all of us. (catholicnewsagency.com)
  • Some people are very uneasy about creating a human embryo and then dismembering it, however early the stage, to obtain embryonic stem cells from which useful tissues might be grown. (globalchange.com)
  • The resulting embryo is then implanted into a surrogate mother, resulting in the birth of an animal genetically identical to the body cell donor. (geminigenetics.com)
  • Therapeutic cloning involves the creation of an early-stage embryo (blastocyst) and the removal of stem cells from the developing embryo. (geminigenetics.com)
  • An electrical impulse is then applied to the egg cell to stimulate it to become an embryo. (geminigenetics.com)
  • Though pet cloning may be considered a relatively new technology, the process of cloning as defined above is first documented in 1885, where Hans Adolf Eduard Driesch demonstrated artificial embryo twinning on a sea-urchin. (geminigenetics.com)
  • creates a cloned embryo. (nationalrighttolifenews.org)
  • A cloned embryo-like a natural embryo-is an individual organism, a member of its (in this case, human) species. (nationalrighttolifenews.org)
  • After that, the question becomes not whether to clone, but what to do with the embryo that was created through the cloning process. (nationalrighttolifenews.org)
  • The Los Angeles Times has waded in to the junk biology game, assuring us that no embryos are threatened in human cloning-WHEN THE WHOLE POINT OF HUMAN CLONING IS TO CREATE AN EMBRYO! (nationalrighttolifenews.org)
  • They isolate skin cells, then using the same procedure that created Dolly, they create an embryo from them. (biologywriter.com)
  • The egg with its skin cell nucleus is allowed to form a 120-cell embryo. (biologywriter.com)
  • The embryo is then destroyed, its cells used as embryonic stem cells for transfer to injured tissue. (biologywriter.com)
  • The mouse experiment carried out by the Rockefeller researchers would have been far more controversial if it had been carried out in humans, because the 120-cell embryo could in principle be brought to term by inserting it into a human uterus. (biologywriter.com)
  • increased public sensitivity and awareness together with the development of national regulations of governance of human cloning and embryo research in general. (lifeissues.net)
  • 3. National regulations of governance of human cloning and embryo research in general adopted so far confirm the convergence of views of the refusal to adopt legislation or guidelines permitting reproductive cloning , while they still show variations on the legitimacy of human cloning carried out as part of research agendas. (lifeissues.net)
  • Researchers create embryonic stem cells without embryo. (curtisrobertmacdonald.com)
  • Embryonic stem cell research, however, poses serious ethical concerns because it requires destroying an embryo in order to obtain the cells. (catholicphilly.com)
  • 2. Nuclear transfer is a technique used to duplicate genetic material by creating an embryo through the transfer and fusion of a diploid cell in an enucleated female oocyte.2 Cloning has a broader meaning than nuclear transfer as it also involves gene replication and natural or induced embryo splitting (see Annex 1). (who.int)
  • Under three Presidential Administrations, Dr. Skirboll was the agency's lead on policy issues related to fetal tissue, cloning, and stem cell research. (wikipedia.org)
  • In this article R. Alta Charo states that we have a right to use fetal tissue for research and therapy (Fetal Tissue, 1) The article goes into how a lot of people find this to be a moral issue and a matter of the conscience and explains how the antiabortion activist that don't agree with the research are actually benefitting from the fetal tissue. (ipl.org)
  • Depending on the source, stem cells can be classified into two broad categories i.e. embryonic stem cells that are derived from embryos and non-embryonic stem cells that are derived from adult and fetal tissues. (benthamscience.com)
  • How can technologies like cloning, embryonic stem cells, fetal-tissue vaccines, and designer genetic screening be wrong if they help people? (olcworcester.com)
  • They can be used to study cellular and metabolic biology without the use of an animal model or fetal tissue. (nature.com)
  • 1983) and the multipotent progenitor cells from fetal disease (Bjorklund and Lindvall, 2000). (lu.se)
  • The stem cells suits human needs, does not cause harm and can be obtained from both adult and fetal does not conflict with religious beliefs, it has tissues, umbilical cord and early embryos. (who.int)
  • This Study presents the first use in somatic cell nuclear transfer (SCNT) of tooth Pulp cells containing progenitor cells that resemble the nonaging embryonic connective tissue in adults. (yildiz.edu.tr)
  • The Notch signaling pathway provides important intercellular signaling mechanisms essential for cell fate specification and it regulates differentiation and proliferation of stem or progenitor cells by para-inducing effects 3-4 . (bvsalud.org)
  • Recent studies have isolated distinct cell populations from infantile hemangiomas that display properties equivalent to aberrant progenitor cells, suggesting that, in addition to malignant tumors, benign tumors may also contain a stem cell-like component. (medscape.com)
  • To varying degrees, these fates also extend to the Such state stability is required in stem and progenitor cells to immediate progeny of stem cells, known as progenitor or support self-renewal and maintenance of the uncommitted transit-amplifying cells. (lu.se)
  • Using tooth Pulp Cells ill SCNT increased the first cleavage rates compared with adult somatic Cells, leading to a higher rate of DNA reprogramming and increased production of an identical embryonic stem cells (ESCs) line. (yildiz.edu.tr)
  • These cells were named Osmangazi Turk Identical ESCs since this was the first use in SCNT of tooth pulp cells to demonstrate a decrease in glucose levels following administration of these cells. (yildiz.edu.tr)
  • Under such circumstances, the idea of "therapeutic cloning" was proposed, indicating the generation of ESCs from SCNT embryos for therapeutic purpose. (benthamscience.com)
  • Successful somatic-cell nuclear transfer (SCNT) depends on the quality, availability and maturation of the animal's unfertilized oocytes. (nature.com)
  • For SCNT, the chromosomes of the unfertilized canine oocytes were removed by micromanipulation, and a single donor cell was transferred into each enucleated oocyte. (nature.com)
  • Once the SCNT is done, the cloning is over. (nationalrighttolifenews.org)
  • Most embryos…formed one or two pronuclei at the time of removal from TSA, whereas a slightly higher portion of embryos cleaved…suggesting that some SCNT embryos did not exhibit visible pronuclei at the time of examination… Most cleaved embryos developed to the eight-cell stage…but few progressed to compact morula…and blastocyst. (nationalrighttolifenews.org)
  • Activation of embryonic genes and transcription from the transplanted somatic cell nucleus are required for development of SCNT embryos beyond the eight-cell stage…Therefore, these results are consistent with the premise that our modified SCNT protocol supports reprogramming of human somatic cells to the embryonic state. (nationalrighttolifenews.org)
  • The cloning is completed when the SCNT is accomplished. (nationalrighttolifenews.org)
  • Little noted in all of the caterwauling, was that ESCR and human-cloning research (SCNT) have been funded bounteously-to the tune of nearly $2 billion. (lifelegaldefensefoundation.org)
  • Not only has the National Institutes of Health put more than $150 million in recent years into human ESCR (about $40 annually), but according to a recent report put out by the Rockefeller Institute, to date about $1.7 billion has poured into ESCR and SCNT from philanthropic sources-and this doesn't include the hundreds of millions granted annually by the states for cloning and ESCR experiments. (lifelegaldefensefoundation.org)
  • Human cloning via SCNT was redefined from "therapeutic cloning" in the advocates' lexicon to merely "stem-cell research. (lifelegaldefensefoundation.org)
  • Amendment 2 in Missouri-which established a constitutional right in Missouri to conduct human cloning research-was expected to cruise to an easy victory, proving that even in the Bible Belt, people wanted scientists to pursue ESCR/SCNT. (lifelegaldefensefoundation.org)
  • 1] Therapeutic cloning, on the other hand, creates human embryos merely as a source of embryonic stem cells. (reasons.org)
  • Hwang was the first scientist to publish a paper showing, in 2004, that his team had actually cloned a human cell to provide a source of embryonic stem cells -- master cells that can provide a source of any type of tissue or cell in the body. (blogspot.com)
  • The exact process of differentiation is not yet understood and although embryonic stem cells can, in principle, provide for all human tissue, scientists are some way from controlling the process. (spiked-online.com)
  • This study describes for the first time, a differentiation system that does not require co-culture with animal cells or products, thus allowing the production of pathogen-free RPE cells suitable for transplantation into patients. (news-medical.net)
  • There are important problems in the therapeutic use of cloning which increase with the more advanced differentiation of somatic cells. (yildiz.edu.tr)
  • Stem cells are not specialized and the process of their specialization is called differentiation. (benthamscience.com)
  • The learning resource provides an overview of stem cells, explains differentiation, embryonic, adult and induced pluripotent stem cells, theraputic stem cell cloning and stem cells as potential treatment for heart disease and nerve damage. (schoolscience.co.uk)
  • Our scientists have developed a wide array of stem cell-focused reagents and resources for many applications including flow cytometry , western blotting , ELISAs , and recombinant proteins for cell differentiation. (biolegend.com)
  • RUNX1 is also required for the differentiation of CD8+, Th17, and regulatory T cells. (biolegend.com)
  • These findings revealed that RUNX1 acts as a tumor suppressor for myeloid leukemia and is crucial for the development and terminal differentiation of several blood cell lineages 2,3 . (biolegend.com)
  • Here we show the differentiation of patient specific iPSCs derived from a patient with SFTPB deficiency into lung organoids with mesenchymal and epithelial cell populations from both the proximal and distal portions of the human lung. (nature.com)
  • After differentiating the mutant and corrected cells into lung organoids, we show expression of SFTPB mRNA during endodermal and organoid differentiation but the protein product only after organoid differentiation. (nature.com)
  • Although many differentiation protocols in the literature have been successful in mimicking lung development from stem cells, there has not been an examination of how a specific mutation impacts the differentiation process including its effects on the early endoderm, as well as the proximal and distal lung epithelial cell populations in the lung organoids. (nature.com)
  • Aim: To detect the expression of molecules associated with Notch signaling pathway in stem cells from human exfoliated deciduous teeth (SHED) cultured in specific differentiation medium, namely, keratinocyte growth medium (KGM). (bvsalud.org)
  • Notch-1, Jagged-1, Jagged-2, and stem cell marker Nanog are expressed in SHED cultured in KGM which may be involved in the differentiation into epithelial-like cells in human dental pulp tissues. (bvsalud.org)
  • Since the Notch signaling pathway molecules play an important role in differentiation of epithelial cells, it is important to identify the presence of notch signaling molecules in SHED during the process of cell differentiation. (bvsalud.org)
  • Notch signaling pathway is also involved in the regulation of epithelial cell differentiation in various tissues 5-6 . (bvsalud.org)
  • Stem and progenitor cell populations are often heterogeneous, which may reflect stem cell subsets that express subtly different properties, including different propensities for lineage selection upon differentiation, yet remain able to interconvert. (lu.se)
  • A key challenge is to understand how state, but must also afford flexibility in cell-fate choice to permit the different cell-fate options confronting stem and progenitor cell-type diversification and differentiation in response to cells are selected and coordinated such that adoption of a given intrinsic cues or extrinsic signals. (lu.se)
  • Evidence the fate of stem cells has broad ramifications for biomedical suggests that during development or differentiation, cells make science from elucidating the causes of cancer to the use of very precise transitions between apparently stable ``network stem cells in regenerative medicine. (lu.se)
  • Scientists were initially interested in somatic-cell nuclear transfer as a means of determining whether genes remain functional even after most of them have been switched off as the cells in a developing organism assume their specialized functions as blood cells, muscle cells, and so forth. (who.int)
  • The fact that the DNA of a fully differentiated (adult) cell could be stimulated to revert to a condition comparable to that of a newly fertilized egg and to repeat the process of embryonic development demonstrates that all the genes in differentiated cells retain their functional capacity, although only a few are active. (who.int)
  • Alternatively, transgenesis and gene targeting techniques can be used to introduce the patient's genes into the stem cell line. (spiked-online.com)
  • Safeguards, such as suicide genes to destroy implanted tissue, will have to be considered. (spiked-online.com)
  • But previous approaches required the use of viruses to deliver the four genes needed to activate the cell and accomplish that task. (cbc.ca)
  • Then we will select clones that are resistant to damage from mutagens and oxidants, and thus may have incorporated the new genes in patterns useful for generalized cellular protection. (jax.org)
  • They took a cell from Dr Jose Cibelli, a research scientist and combined it with a cows egg from which the genes had already been removed. (globalchange.com)
  • The genes activated and the egg began to divide in the normal way up to the 32 cell stage at which it was destroyed. (globalchange.com)
  • Technically 1% of the human clone genes would have belonged to the cow - the mitochondria genes. (globalchange.com)
  • Numerous biological components, including genes, cells, tissues, and even complete creatures like sheep, have been cloned by researchers, and now cat, dog and equine cloning is widely and reliably available via international companies such as our partner, ViaGen Pets & Equine. (geminigenetics.com)
  • The underphosphorylated, active form of Rb interacts directly with E2F1 , leading to cell cycle arrest, while the hyperphosphorylated form decouples from E2F1, thus promoting the transcription of genes promoting entry into the S phase. (biolegend.com)
  • Below is a non-exhaustive list of in-house infrastructures that are categorized into three overarching themes: bio-imaging, proteins, genes & cells and other resources. (lu.se)
  • Below you can see some examples of the infrastructure for research on genes and cells, available for researchers at Lund University. (lu.se)
  • In addition to infrastructures for bioimaging, protein and genes & cells, we also provide other resources e.g., databases, networks and specialized labs. (lu.se)
  • explosion further, consider that a fictitious small genome with 2002) More recently and more dramatically, the potential for 260 genes would host the same number of combinations as cell state conversions is exemplified by the reprogramming of the number of atoms in the visible universe! (lu.se)
  • Meanwhile, on the IPSC [induced pluripotent stem cells] front, [Dr. Shinya] Yamanaka-who refused to use embryonic stem cells because he saw his own children in them-has increased the efficiency of a method of creating pluripotent stem cells that don't appear to cause tumors. (nationalrighttolifenews.org)
  • He and his fellow researchers then used the snow leopard cells to create induced pluripotent stem (iPS) cells, also known as embryonic stem-like cells. (scientificamerican.com)
  • Embryonic stem cells are pluripotent - they have the ability to become virtually any type of cell within the body. (cbc.ca)
  • Kuldip S. Sidhu , " Frontiers in Pluripotent Stem Cells Research and Therapeutic Potentials Bench-to-Bedside ", Bentham Science Publishers (2012). (benthamscience.com)
  • Induced pluripotent stem cells, another types of pluripotent stem cells derived from any tissue by reprogramming and are the homologous source of stem cells. (benthamscience.com)
  • As if it were induced pluripotent stem cells, which really do turn skin into stem cells. (nationalrighttolifenews.org)
  • But what is not getting such wide reporting is the use of pluripotent stem cells (as well as many other types of cells and genetic engineering techniques) for reproductive purposes . (lifeissues.net)
  • Researchers have developed new, non-destructive methods to produce cells with all the properties of embryonic stem cells (called "induced Pluripotent Stem Cells" or iPSC) by "reprogramming" adult cells. (catholicphilly.com)
  • even though it was politically unpopular, the President believed wholeheartedly that the raw talent, intelligence, and creativity of the science sector would find a way to obtain pluripotent stem cells (the ability to become any cell type) through ethical means. (lifelegaldefensefoundation.org)
  • Surfactant is produced by alveolar type II cells which can be differentiated in vitro from patient specific induced pluripotent stem cell (iPSC)-derived lung organoids. (nature.com)
  • They are 3-dimensional, complex, multicellular structures that can be derived from patient specific human induced pluripotent stem cells (hiPSCs). (nature.com)
  • Human heart tissues grown as three-dimensional spheroids and consisting of different cardiac cell types derived from pluripotent stem cells (hiPSCs) recapitulate aspects of human physiology better than standard two-dimensional models in vitro. (bvsalud.org)
  • An induced pluripotent stem cell (iPSC) line, in which a H2B-fluorescent protein fusion is temporally expressed, is a valuable tool to track cells and study cell divisions and apoptosis. (bvsalud.org)
  • Recently, in combination with cardiomyocytes derived from human (induced) pluripotent stem cells they have started to become a preferred tool to examine newly developed drugs for potential cardiac toxicity in pre-clinical safety pharmacology. (bvsalud.org)
  • We then validated the model in both primary mouse- and human pluripotent (embryonic) stem cell-derived cardiomyocytes showing that field potentials measured in MEAs could be converted to action potentials that were essentially identical to those determined directly by electrophysiological patch clamp. (bvsalud.org)
  • In reality, gene somatic cells to a pluripotent cell state by a handful of transcrip- expression is graded, making the potential gene expression tion factors (Takahashi and Yamanaka, 2006). (lu.se)
  • Researchers hope to use these cells to grow healthy tissue to replace injured or diseased tissues in the human body. (medlineplus.gov)
  • The researchers then used these cells as the source of genetic material to clone pigs with organs that lacked the sugar groups responsible for HAR. (reasons.org)
  • And the researchers have already accomplished the first step, creating embryonic stem-like cells from the tissue of an endangered adult snow leopard ( Panthera uncia ). (scientificamerican.com)
  • Recently, researchers from the Sanger Institute (UK) have isolated stable and germline competent embryonic stem (ES) cells from C57BL/6N mice (1). (umassmed.edu)
  • Researchers there are working on technology that induces human skin cells to change into the kind of stem cells that have been created by embryos. (cbc.ca)
  • However, researchers at the Harvard Stem Cell Institute say reprogrammed cells won't eliminate the need or value of studying embryonic stem cells. (cbc.ca)
  • The researchers of the paper from Advanced Cell Technology, collaborated with scientists from the Institute of Regenerative Medicine at Wake Forest University School of Medicine, Winston-Salem, North Carolina, and the University of Chicago, Chicago, Illinios. (news-medical.net)
  • But their chief objection - that obtaining stem cells requires killing a human being - is about to become moot, as researchers have discovered that human adult stem cells can be differentiated into neural tissue in chicken eggs . (blogspot.com)
  • The researchers stopped well short of creating a human clone. (nationalrighttolifenews.org)
  • US researchers have reported a breakthrough in stem cell research, describing how they have turned human skin cells into embryonic stem cells for the first time. (nationalrighttolifenews.org)
  • Using this procedure, called therapeutic cloning, the researchers succeeded in making cells from the tail of a mouse convert into the dopamine-producing cells of the brain that are lost in Parkinsons disease (figure 48.7). (biologywriter.com)
  • Researchers create embryonic stem cells mature cells turn off some of the epigenetic controls that Stem Cell Science Frequently Asked Questions. (curtisrobertmacdonald.com)
  • After more than 25 years of experiments with embryonic stem cells in animal models, researchers have yet to develop one successful treatment in mice for any disease that could be used as a model to undertake the first steps for a clinical trial with human patients. (freerepublic.com)
  • If this mysterious creature could be captured and grown in the lab, it might change the face of medicine, promising, among other remarkable options, the ability to grow replacement human tissue at will … [but] these cells are found only in embryos or very immature fetuses, and pro-life forces have targeted the researchers who are hunting for ES cells, hoping to stop their science cold. (technologyreview.com)
  • Human cloning is intrinsically illicit in that, by taking the ethical negativity of techniques of artificial fertilization to their extreme, it seeks to give rise to a new human being without a connection to the act of reciprocal self-giving between the spouses and, more radically, without any link to sexuality. (archdiocese-no.org)
  • From the ethical point of view, so-called therapeutic cloning is even more serious. (archdiocese-no.org)
  • Clonaid's claim to have produced the first human clones propelled the ethical debate about human cloning to the headlines last December. (reasons.org)
  • Embryonic stem cell transplants have been an ethical, social, and legal controversy since the first successful transplant of human stem cells in 1998. (ipl.org)
  • The recent desperation to clone human embryos may be seriously undermining accepted ethical principles of medical research, with potentially profound wider consequences. (lifeissues.net)
  • However, the derivation of human NT-ESCs goes with the destruction of clone embryos, leading to fierce ethical disputes. (benthamscience.com)
  • Scientists, many of whom are sold on utilitarian-based ethical analysis, try to downplay the issue of human life in stem-cell research. (catholicnewsagency.com)
  • In particular, scientific developments in areas such as iPS cells open new possibilities of research and, at mid term, of therapeutic applications, but they also bring new ethical challenges and problems requiring further reflection and debate. (lifeissues.net)
  • Stem cell research and ethical dilemmas How far have we. (curtisrobertmacdonald.com)
  • Stem cell research and ethical dilemmas: How far have The two possible suggestions to counteract this slope is to either Stem cell uses have advanced, Some unipotent stem cells, such as mesenchymal stem cells. (curtisrobertmacdonald.com)
  • The mass production of human embryos also poses important ethical challenges, including the cloning of human embryos in laboratories for research purposes and the probable exploitation of women to obtain the eggs needed for such production. (catholicphilly.com)
  • We now have the right mechanism for sourcing cells without ethical quibbles,' said Peter Mountford, head of the Melbourne- and London-based Stem Cell Sciences. (freerepublic.com)
  • New discoveries pave the way for ethical stem-cell research, thanks to the president's policies. (lifelegaldefensefoundation.org)
  • A moody 1998 cover of MIT Technology Review predicted the arrival of embryonic stem cells-and of an ethical controversy. (technologyreview.com)
  • To make matters worse, human ES cells could conceivably provide a vehicle for the genetic engineering of people, and the ethical dilemmas surrounding human cloning threaten to spill over onto this field. (technologyreview.com)
  • Cloning technology, however, is perceived as having the potential for reproductive cloning, which raises serious ethical and moral concerns. (who.int)
  • Therapeutic cloning, which creates embryonic stem cells . (medlineplus.gov)
  • One of the most promising techniques is what is known as therapeutic cloning. (spiked-online.com)
  • What deserves greater attention, however, is therapeutic cloning, a (potential) cloning application considered far more important to the biomedical and scientific communities and one far more ethically challenging. (reasons.org)
  • Crudely put, therapeutic cloning looks to generate human embryos solely for the body parts they can provide. (reasons.org)
  • He followed this up with what appeared to be the first proof of the promise of so-called therapeutic cloning -- the creation of 11 separate batches or lines of stem cells taken from actual patients. (blogspot.com)
  • With therapeutic cloning, or the creation of banks of stem cells generated using parthenogenesis (perhaps as few as 40-400 lines), a limitless supply of immune-matched cells could be generated for most of the population. (news-medical.net)
  • The reader benefits from the scholar's clear explanation about embryonic stem-cell research and therapeutic cloning. (catholicnewsagency.com)
  • What's the difference between therapeutic cloning and reproductive cloning? (wisdomanswer.com)
  • Gene cloning, also known as DNA cloning, is a very different process from reproductive and therapeutic cloning. (wisdomanswer.com)
  • Therapeutic cloning refers to the production of embryonic stem cells for medicinal reasons, for example regenerative medicine and tissue replacement. (geminigenetics.com)
  • Therapeutic cloning successfully addresses the key problem that must be solved before stem cells can be used to repair human tissues damaged by heart attack, nerve injury, diabetes, or Parkinsons, which is immune acceptance. (biologywriter.com)
  • Therapeutic cloning uses has some deficiency regarding the use of stem cells? (curtisrobertmacdonald.com)
  • 5. In 2001, France and Germany requested the United Nations General Assembly to develop international conventions on human reproductive cloning, therapeutic cloning and research on stem cells. (who.int)
  • Therapeutic cloning possesses enormous potential for revolutionizing medical and thera- peutic techniques. (who.int)
  • This is therapeutic cloning. (who.int)
  • This cell then has therapeutic cloning: the global the capacity to divide and grow into an exact replica of the original from whom the debate somatic cell was taken. (who.int)
  • Your gene sequences and cells may be patented and sold on the open market without your ever knowing about it. (i-sis.org.uk)
  • 3] An international research team genetically engineered pig cells that lacked a functional form of the gene that codes for a key enzyme involved in the production of the cell surface sugars that cause HAR. (reasons.org)
  • The UMass Chan TAMC has routinely utilized a subclone (MK6) of 129 SVevBrd derived ES cells in gene-targeting experiments. (umassmed.edu)
  • These ES cells allow for the generation of gene‐targeted mice on a C57BL/6 genetic background without the need for multiple backcrossing of mice. (umassmed.edu)
  • To generate suitable C57BL/6 embryonic stem cells for gene targeting experiments, the Sanger team established a male cell line (JM8) from the N-substrain of C57BL/6 mice. (umassmed.edu)
  • The Sanger group performed gene targeting in the JM8 ES cells to delete the retrotransposon from the agouti locus and restore agouti gene function, permitting the visualization of ES cell-derived mice on an inbred C57BL/6 background by agouti coat color. (umassmed.edu)
  • On e of the wardens protecting these animals in Chillingham Cattle Park, Denene Crossley, states how "being isolated, they've managed to essentially purify their gene pool, to the point where they're natural clones of each other. (geminigenetics.com)
  • Molecular cloning refers to the production of multiple copies of a DNA fragment or gene. (geminigenetics.com)
  • Gene cloning refers to the identification and duplication of a single gene or a DNA segment, for the intention of investigating its function or creating a particular protein. (geminigenetics.com)
  • The capability of these cells to differentiate depends on the stem cell type, the regulation of gene expression by various transcription factors and interaction with the stem cell niche 1,4 . (biolegend.com)
  • RUNX1 regulates CD4 gene transcription during multiple stages of T cell development and represses the CD4 gene in CD4-CD8- (double negative) T cells. (biolegend.com)
  • Pax-6 acts as a critical gene for the development of eyes and other sensory organs, certain neural and epidermal tissues as well as other homologous structures, usually derived from ectodermal tissues. (biolegend.com)
  • Gene therapy has been utilized successfully to repair or inactivate mutations in animal models of monogenic human diseases 19 as well as human in vitro cells 12 . (nature.com)
  • Similarly, GATA-1 has been shown to induce lineage switching expression values even if, for simplicity, we assume only ``on'' of committed cells in hematopoiesis, first in cell lines (Kulessa and ``off'' states for each gene. (lu.se)
  • The resulting tissue will be an almost exact genetic match to the patient and will therefore not face rejection and transplantation can be made much safer without the need for immune suppression. (spiked-online.com)
  • One such approach, called "xenotransplantation" (the transplantation of living cells, tissues, and organs from one species to another species), turns to pigs as a source of organs for human transplants. (reasons.org)
  • However, tissue rejection following ESCs derivatives transplantation greatly hinders its application. (benthamscience.com)
  • The Law on Transplantation of Organs, Tissues, and Cells (promulgated SG No. 83/19 September 2003, into force 1 January 2004) regulates the use, collection and storage (including biobanks) of all cells, organs and human tissue in Bulgaria. (eurostemcell.org)
  • Law on the Transplantation of Organs, Tissues and Cells (Promulgated in the State Gazette, issue No. 83/19 September 2003, entered into force on 1 January 2004), at http://bgtransplant.bg/iat/docs/Law%20on%20transplantation.doc (Word download), accessed 10 October 2011. (eurostemcell.org)
  • as well as diagnostic techniques, drug development and tissue transplantation. (who.int)
  • Xenotransplantation involves the transplantation of nonhuman tissues or organs into human recipients. (medscape.com)
  • The motivation for using animal sources for organ or tissue transplantation is driven by supply and demand. (medscape.com)
  • In biology , cloning is the process of producing similar populations of genetically identical individuals that occurs in nature when organisms such as bacteria , insects or plants reproduce asexually . (wikiquote.org)
  • The study of biology of stem cells is the hallmark of the recent emerging field of regenerative medicine and medical biotechnology. (benthamscience.com)
  • The first half of the course will cover cell fate restrictions, cloning animals using nuclear transfer, stem cell biology, formation of the embryonic axes in vertebrates and Drosophila, and patterning of the neural tube and mesodermal tissues. (upenn.edu)
  • The junk biology is flying in the media's descriptions of the now accomplished human cloning. (nationalrighttolifenews.org)
  • Based on the physical characteristics of the sample, biobanks can be classified into several categories, such as tissue biobanks, cell biology banks, and blood biobanks. (technavio.com)
  • One of the greatest controversies triggered tissue, a stem cell encoding for heart tissue by the rapid pace of evolution in biology, will eventually develop into heart tissue particularly in genomics and biotechnology, and so on. (who.int)
  • Our facilities provide the opportunity to study protein structure, molecular probes and drug design, system biology and molecular interactions in cells and tissues. (lu.se)
  • Understanding cell-fate decisions in stem cell populations is a major goal of modern biology. (lu.se)
  • Scientists anticipate that in the future stem cell lines will provide a virtually unending supply of pancreatic cells for diabetic patients, neuronal cells for patients with neural disorders such as Parkinson's or Alzheimer's disease, and a host of heart cells that may treat a variety of cardiac problems. (spiked-online.com)
  • It might be expected that the richest nation on Earth would encourage its top scientists to pursue this work with vigor rather than limiting funding opportunities, creating legal barriers and fencing off any newly developed cell lines. (spiked-online.com)
  • A number of scientists are trying to create life in the lab, specifically artificial cells. (reasons.org)
  • Example: In Japan, scientists have discovered the chemical that induces bone marrow to produce healing cells. (nationalrighttolifenews.org)
  • The chemical which summons stem cells from bone marrow to the site of a wound has been discovered by scientists in the UK and Japan. (nationalrighttolifenews.org)
  • Scientists at Osaka University and King's College London gave mice bone marrow cells that glow green - which can be tracked while moving round the body. (nationalrighttolifenews.org)
  • Scientists have been all abuzz in the last few years over stem cells - cellular magicians that promise to dazzle and amaze. (cbc.ca)
  • Scientists say embryonic stem cells are the most useful type because they have the potential to become any type of cell within the body. (cbc.ca)
  • Scientists are fascinated by the ability of stem cells to become any type of cell. (cbc.ca)
  • Let's wind back the clock: these scientists had already carried out successful human nuclear transfer into an unfertilised egg before Dolly the sheep clone had been made. (globalchange.com)
  • Scientists have already made geep (combined sheep and goat), and camas (combined camels and lamas) simply by rolling two balls of cells together after fertilisation. (globalchange.com)
  • Scientists have used cloning technology to transform human skin cells into embryonic stem cells, an experiment that may revive the controversy over human cloning. (nationalrighttolifenews.org)
  • These scientists destroyed the embryos and derived stem cell lines. (nationalrighttolifenews.org)
  • The method described on Wednesday by Oregon State University scientists in the journal Cell, would not likely be able to create human clones, said Shoukhrat Mitalipov, senior scientist at the Oregon National Primate Research Center. (nationalrighttolifenews.org)
  • By surgically transplanting embryonic stem cells, scientists have performed the remarkable feat of repairing disabled body tissues in mice. (biologywriter.com)
  • Some of the most serious A significant hurdle to this use and most uses of stem cells is that scientists do not yet it may become possible to generate healthy What specific types of conditions can stem cell therapy help treat? (curtisrobertmacdonald.com)
  • Professor Alan Mackay Sim's Queensland team of scientists working on nasal stem cell research for spinal cord injuries and Professor Pritinder Kaur's team at Peter MacCallum Cancer Centre working on using adult stem cells for burns victims are both supported by grants from the Sydney archdiocese. (freerepublic.com)
  • Umbilical Cord Blood Storage Company Sees Growth Umbilical Cord Stem Cell Storage Resources Arkansas House Votes to Create Umbilical Cord Stem Cell Bank Scientists Claim They Discovered Molecule That Might Help Embryonic Stem Cells Grow US Senate Vote for. (physiciansforlife.org)
  • 1. Cloning is an umbrella term traditionally used by scientists to describe different processes for duplicating biological material. (who.int)
  • The con- is removed and replaced by a nucleus of cept of human cloning has long been in the another cell type, the stem cell will then imagination of many scientists, scholars and be reprogrammed to produce the product fiction writers [ 1 ]. (who.int)
  • In English, this means no need for abortions or embryonic cloning, as the cells can be sourced from the patient's own bone marrow (eliminating rejection problems into the bargain). (blogspot.com)
  • Bone-marrow stem cells appeared to prevent the worsening of progressive MS. People with Type-1 diabetes were cured with their own adult stem cells. (lifelegaldefensefoundation.org)
  • A renewable, tissue culture source of human cells capable of differentiating into a wide variety of cell types would have broad applications in basic research and therapeutic techniques. (spiked-online.com)
  • Healthy mice have been cloned from cells from dead mice that had been frozen for 16 years, raising the possibility that endangered species could be cloned from old carcasses that have been tossed in freezers, rather than from living cells frozen using elaborate techniques. (newscientist.com)
  • Other teams have already cloned mice from previously frozen dead cells . (newscientist.com)
  • In mice without grafts, very few stem cells travelled to the wound. (nationalrighttolifenews.org)
  • Furthermore, 129-strain ES cells often contribute to the germline of the chimeras, and when breeding chimeras with C57BL/6 test mice, the dominant agouti color in offspring signifying germline transmission is also easily detected in the G1 generation litters. (umassmed.edu)
  • When these C57BL/6N-based JM8 cells were injected into blastocysts from albino mice, a high proportion of chimeras displayed ES cell contribution to both germline and somatic tissues. (umassmed.edu)
  • Since these JM8A3 cells are heterozygous for the corrected agouti allele [A tm1brd ], crossing the resulting brown-on-white chimeras with C57BL/6N test mice yield embryonic stem cell-derived offspring with either agouti or black coats. (umassmed.edu)
  • However, one still has to genotype all of the G1 generation mice from germline transmitting chimeras or risk losing some black colored mice that are ES cells derived. (umassmed.edu)
  • RUNX1-deficient mice fail to generate hematopoietic stem cells. (biolegend.com)
  • Embryonic stem cells of mice have been induced to become insulin-secreting pancreas cells. (biologywriter.com)
  • While exciting, these advances in stem cell research were all done in strains of mice without functioning immune systems. (biologywriter.com)
  • This prevents the mice from rejecting transplanted stem cells as foreign. (biologywriter.com)
  • The stage-specific embryonic antigen 4 (SSEA4) is com- isolate the NSCs from neonatal mice and rats (Campos monly used as a cell surface marker to identify the pluri- et al. (lu.se)
  • Immunohisto- have been used for positive selection of NSCs from em- chemistry on human embryonic central nervous system bryonic mice (Nagato et al. (lu.se)
  • Somatic-cell nuclear transfer, the technique by which Dolly was created, was first used 40 years ago in research with tadpoles and frogs. (who.int)
  • The nucleus of an adult somatic cell (such as a skin cell) is removed and transferred to an enucleated egg, which is then stimulated with electric current or chemicals to activate cell division. (who.int)
  • if it implants and the pregnancy goes to term, the resulting individual will carry the same nuclear genetic material as the donor of the adult somatic cell. (who.int)
  • Here, the stem cell line is created using the genetic properties of the prospective recipient via somatic cell nuclear transfer. (spiked-online.com)
  • Figure 1: Dog cloned by somatic-cell nuclear transfer. (nature.com)
  • Cloning describes the processes used to create an exact genetic replica of another cell, tissue or organism. (medlineplus.gov)
  • XI - embryonic stem cells: embryonic cells that are capable of modifying the cells of any organism tissue. (hinxtongroup.org)
  • Organism cloning (also called reproductive cloning) refers to the procedure of creating a new multicellular organism, genetically identical to another. (wisdomanswer.com)
  • Cloning or clone reproduction is an in vitro process of obtaining multiple copies of the same organism using molecular biological and genetic engineering techniques. (wisdomanswer.com)
  • A new organism is created by asexual reproduction using a duplicate of a single cell from the parent organism. (geminigenetics.com)
  • This is the most known form of cloning and involves creating a genetically identical replica of a whole organism. (geminigenetics.com)
  • The process of reproductive cloning involves the nucleus of a somatic (body) cell from a donor organism to be cloned being transferred into an egg cell whose nucleus (genetic material) has been removed. (geminigenetics.com)
  • A clone is an organism that is a genetic copy of an existing one. (who.int)
  • Blastocytes obtained through nuclear transfers would be used to generate the embryonic stem cells that could be differentiated to specific tissues or organs for transfer to the nuclear donor. (spiked-online.com)
  • Implanting replacement tissue into damaged and diseased organs would provide the opportunity to treat and possibly cure many dreaded diseases and debilitating injuries. (reasons.org)
  • They are in an early stage of development and have the ability to become any type of cell to form skin, bones, organs or other body parts. (cbc.ca)
  • The reproductive cloning of people is prohibited, including that for the purposes of donating organs, tissues and cells. (eurostemcell.org)
  • And yet, all of us would be appalled at the idea of terminating their lives so we could harvest their tissues or organs in order to save others," she says, in reference to the common utilitarian argument that embryonic stem-cell research is valid in an effort to find cures that could save people's lives. (catholicnewsagency.com)
  • Our facilities provide the opportunity to study molecules, cells, organs and entire organisms. (lu.se)
  • However, an animal created through this technique would not be a precise genetic copy of the source of its nuclear DNA because each clone derives a small amount of its DNA from the mitochondria of the egg (which lie outside the nucleus) rather than from the donor of cell nucleus. (who.int)
  • Human nuclear cell transfer is legal in the UK, but is liable to become a criminal act in the USA pending an upcoming vote in the Senate. (spiked-online.com)
  • More than 100 nuclear transfer procedures could be required to produce one viable clone. (wikiquote.org)
  • Mouse nuclear transfer embryonic stem cells (NT-ESCs) were first established in 2000, and then proved to be able to differentiate either in vivo or in vitro, and give rise to individual tissues through germ line transmission or tetraploid complementation. (benthamscience.com)
  • Here we describe the cloning of two Afghan hounds by nuclear transfer from adult skin cells into oocytes that had matured in vivo . (nature.com)
  • 3. Media reports on nuclear transfer are usually about one form, reproductive nuclear transfer, also known as reproductive cloning of human beings . (who.int)
  • In neu- fatal neurologic disease of horses and sheep, owes rons, sometimes in glia cells, acidophilic intra- its name to the town Borna in Saxony, Germany, nuclear inclusion bodies, called Joest-Degen inclu- where a large number of horses died during an sion bodies, are occasionally found. (cdc.gov)
  • Help us to be faithful to this sacred trust so that we may protect and promote the dignity of every human life from the very moment of conception, particularly the tiniest humans in the embryonic stage of human development who are so often forgotten by society & used by modern science. (archdiocese-no.org)
  • Those two factors make attempts to clone humans for reproductive purposes ethically troubling. (reasons.org)
  • Potentially easier would be cloning cryogenically frozen humans, though the consensus among cloning experts is that it would be unethical and dangerous to clone a human. (newscientist.com)
  • An important next step will be to test the ability of these cells to restore visual function in both humans and animal models. (news-medical.net)
  • Review of Critical Article: Cobbe, 'Why the apparent haste to clone humans? (lifeissues.net)
  • See Neville Cobbe, "Why the apparent haste to clone humans? (lifeissues.net)
  • Humans and other mammals may produce natural clones, commonly referred to as identical twins. (geminigenetics.com)
  • 2002). In humans, SSEA4 is expressed by building the nervous system but also for their prospec- nonneural cells such as the erythrocytes (Kannagi et al. (lu.se)
  • While at the hospital she was unaware that the doctors there were experimenting on her taking cell samples from her body, to help find a resolution to multiple diseases. (ipl.org)
  • All of this debate raises an important question, Should embryonic stem cell research be conducted for treatment of present and future diseases? (ipl.org)
  • On the other hand, people who believe that embryonic stem cell research creates means of curing diseases reply that the research should be conducted. (ipl.org)
  • Since then, there has been a flurry of announcements about developments in stem cell research and hints of promising treatments for diseases such as Alzheimer's, Parkinson's and cancer. (cbc.ca)
  • In May 2007, Ontario and California announced a $30-million stem cell research deal aimed at finding new therapies for those diseases. (cbc.ca)
  • This makes them perfect for a wide range of medical uses, from repairing tissue to treating diseases such as Parkinson's and Alzheimer's. (cbc.ca)
  • Some of these retinal tissues such as Retinal Pigment Epithelium (RPE) may provide a novel therapeutic strategy for such devastating diseases as macular degeneration, retinitis pigmentosa, and other retinal degenerative diseases. (news-medical.net)
  • Besides use in the aging retina, human embryonic stem cells have now demonstrated the potential to change the face of several age-related degenerative diseases, perhaps one day allowing physicians to prescribe young cells they way they dispense pills today. (news-medical.net)
  • Claims that you could clone individual treatments of human beings to treat common diseases like diabetes, suggests you need a huge supply of human eggs. (wikiquote.org)
  • Stem cells are emerging as an important source of material for diseases in regenerative medicine. (benthamscience.com)
  • Embryonic stem cells (ESCs) can grow infinitely and give rise to all types of cells in human body, thus of tremendous therapeutic potentials for a variety of diseases, such as Parkinson's disease, spinal cord injury, and diabetes. (benthamscience.com)
  • The recovered stem cells can then be used in the treatment of diseases and to aid the recovery of injuries. (geminigenetics.com)
  • The use of various types of stem cells for research purposes to make disease "models" in the lab for regenerative medicine and for "therapies" to cure sick patients for diseases is constantly in the news. (lifeissues.net)
  • information on stem cells, cloning and What diseases and conditions can be treated with stem cells? (curtisrobertmacdonald.com)
  • Potential benefits of stem of stem cells and the realization of these uses, Some of the potential uses of stem cells are to study the way cells function and hopefully that will lead to cures for various diseases like cancer. (curtisrobertmacdonald.com)
  • A virtual cell modeling system, powered by AI, will lead to breakthroughs in our understanding of diseases, argue the cofounders of the Chan Zuckerberg Initiative. (technologyreview.com)
  • Alveolar type II (ATII) epithelial cells synthesize, secrete and recycle all components of surfactant and dysfunction in surfactant metabolism can result in a variety of pediatric lung diseases including respiratory distress syndrome and interstitial lung disease 3 . (nature.com)
  • Egg harvesting and Embryonic Stem-cell Research Pose Serious Threat to Women's Health A congressional hearing last Thursday raised awareness on the risks to women's health and fertility by in vitro fertilization (IVF), human cloning, embryonic stem-cell. (physiciansforlife.org)
  • Additionally, the so touted "potential benefits" are in this case more than questionable, given the great unresolved medical problems - including their propensity to create tumors - that embryonic stem cells pose. (catholicphilly.com)
  • The "stem cell theory of cancer" states that a subpopulation of cells with stem cell-like properties plays a central role in the formation, sustainment, spread, and drug resistant characteristics of malignant tumors. (medscape.com)
  • With the exception of Myc (which was only present in a subset of benign, borderline, and malignant tumors), Oct4, Nanog, Sox2, and Klf4 were detectable at variable levels across both normal and diseased tissues. (medscape.com)
  • Semi-quantitative evaluation of our immunohistochemical staining revealed that protein expression of Oct4, Nanog, Myc, and Sox2, but not Klf4, was significantly increased in benign, borderline, and malignant vascular tumors relative to non-diseased vascular tissue controls. (medscape.com)
  • These findings provide supporting evidence that enrichment for proteins involved in pluripotency is not restricted solely to malignant tumors as is suggested by the "stem cell theory of cancer", but additionally extends to common benign vascular tumors such as hemangiomas. (medscape.com)
  • These cells expressed RPE-specific molecular markers and were capable of phagocytosis, an important RPE function. (news-medical.net)
  • Differentiomics could also be a valuable predictive tool for quality assessment of other ES cell derivatives based on their molecular signature. (news-medical.net)
  • Cloning in biotechnology refers to processes used to create copies of DNA fragments ( molecular cloning ), cells (cell cloning), or organisms . (wikiquote.org)
  • The course will focus on genetic and molecular approaches, but will also cover the comparative anatomy of developing embryos to the extent necessary to understand the conserved aspects of embryonic patterning. (upenn.edu)
  • Some prohibit only cloning for reproductive purposes and allow the creation of cloned human embryos for research, whereas others prohibit the creation of cloned embryos for any purpose. (who.int)
  • The change of term constituted a clever ruse that bundled and confused in people's minds, the morally acceptable advances being made in adult stem-cell research, the morally dubious human cloning project, and the use of "spare" embryos for research that were "going to be discarded anyway. (lifelegaldefensefoundation.org)
  • Advanced Cell Technology is a leading biotechnology company in the emerging field of regenerative medicine. (news-medical.net)
  • Developments in biotechnology have raised new concerns about animal welfare, as farm animals now have their genomes modified (genetically engineered) or copied (cloned) to propagate certain traits useful to agribusiness, such as meat yield or feed conversion. (wikiquote.org)
  • The world's first human clone of an adult has now been made, by an American biotechnology company in Massachusetts, Advanced Cell Technology. (globalchange.com)
  • With an eye on the potential economic benefits of being a biotechnology-friendly state, the same bill authorized the creation of an adult stem cell center. (sagepub.com)
  • Human embryonic stem cell research and the derivation of human embryonic stem cell lines is not directly regulated by Bulgarian legislation, but falls partially within the scope of the Bulgarian Health Act (promulgated SG No. 70/10 August 2004, into force from 1 January 2005). (eurostemcell.org)
  • Given this fanfare, the debate has tended to focus on reproductive cloning-the use of cloning to generate a human being-and its bizarre societal and familial side effects. (reasons.org)
  • Some in the biomedical community hope to develop techniques to generate replacement tissues from these embryonic stem cells. (reasons.org)
  • This new method of generating stem cells does not require embryos as starting points and could be used to generate cells from many adult tissues, such as a patient's own skin cells,' said principal author Andras Nagy, senior investigator at Mount Sinai's Samuel Lunenfeld Research Institute. (cbc.ca)
  • Using the SURVEYOR nuclease assay 13 , we assessed the ability of each Cas9-sgRNA complex to generate indels in human embryonic kidney (HEK) 293FT cells through the induction of DNA doublestranded breaks (DSBs) and subsequent nonhomologous end joining (NHEJ) DNA damage repair (Online Methods). (cdc.gov)
  • Why is tissue culture asexual reproduction? (wisdomanswer.com)
  • Plant cloning, such as the use of plant tissue culture techniques, is an asexual reproduction of plants to produce duplicates from one plant specimen. (wisdomanswer.com)
  • Is cloning asexual reproduction? (wisdomanswer.com)
  • In essence this form of cloning is an asexual method of reproduction, where fertilization or inter-gamete contact does not take place. (wisdomanswer.com)
  • Clones are cells that have come from asexual reproduction or a parent cell. (wisdomanswer.com)
  • What's the difference between Clone reproduction and asexual reproduction? (wisdomanswer.com)
  • The key difference between asexual reproduction and clone reproduction is the setting of the process. (wisdomanswer.com)
  • Asexual reproduction is a natural method used by certain plants, bacteria, and single-celled creatures to create genetically identical offspring, i.e. clones. (geminigenetics.com)
  • We discuss these properties with examples both from the hematopoietic and embryonic stem cell (ESC) systems. (lu.se)
  • This long-sought technique may eventually let doctors create replacement cells for a wide variety of tissues from bits of a patient's own skin. (nationalrighttolifenews.org)
  • CD133+), but are rarely codetected with the neural stem dents, very few human-specific NSC markers have been cell (NSC) marker CD15. (lu.se)
  • Most natural cloning occurs in those species that produce their descendants asexually, that is, without combining the male and female genetic material. (who.int)
  • Although many species produce clonal offspring in this fashion, Dolly, the lamb born in 1996 at a research institute in Scotland, was the first asexually produced mammalian clone. (who.int)
  • Globally, there are several cloning programmes that aim to increase the size of rapidly-dwindling populations of endangered species such as African wildcats, and maintain genetic diversity through one-off clonings of individuals that haven't bred . (newscientist.com)
  • What's more, most conservationists agree that cloning should be considered only as a last resort for species such as the northern white rhino, where all other attempts at conservation have failed, says Paul Bartels, manager of BioBankSA at the National Zoological Gardens of South Africa in Pretoria. (newscientist.com)
  • But as the Web site Wildlife News points out, techniques such as reproduction with iPS cells could be used when a species is down to its last few members and breeding options are few and far between. (scientificamerican.com)
  • Given that we have an efficiency of 1% cloning for livestock species and if only one in a thousand cells are viable then around 100,000 cells would need to be transferred. (wikiquote.org)
  • Recently, research has increased in the area of transplanting embryonic cells across species and growing kidneys and endocrine pancreas cells in situ. (medscape.com)
  • In theraputic cloning, the body readily accepts stem cells because they are cloned from its own tissues, and so pass the immune system s self identity check. (biologywriter.com)
  • Thus, the clone would be genetically identical to the nucleus donor only if the egg came from the same donor or from her maternal line. (who.int)
  • 7. "[footnote 16]: The cloning procedure supplies the oocyte with a complete set of chromosomes, all of which are contained in the nucleus which is transferred into the denucleated oocyte. (lifeissues.net)
  • The Wakayama team used a modified version of a cloning technique in which the nucleus of a mouse cell - in this case a cell from dead tissue that has been frozen and then thawed - is injected into a mouse egg that has had its nucleus removed. (newscientist.com)
  • Wakayama speculates that freezing and thawing the tissue somehow makes it easier to "reprogram" the brain cell nucleus. (newscientist.com)
  • The DNA within the skin sample is cultured and inserted into a donor egg cell whose nucleus (genetic material) has been removed. (geminigenetics.com)
  • The surrogate mum carries the cloned pet for the gestation period and once ready, gives birth to the clone who will be an identical genetic twin to the original pet whose skin sample was used to make the nucleus of the donor egg cell. (geminigenetics.com)
  • The team at OHSU [Oregon Health and Science University], which disclosed its work in a paper published online by Cell, created embryonic stem cells by replacing the nucleus in an unfertilized human egg with the nucleus from a skin cell, then harvesting the resulting stem cells. (nationalrighttolifenews.org)
  • First they remove the nucleus from the skin cell, and then they insert it into an egg whose nucleus has already been removed. (biologywriter.com)
  • When the nucleus of a stem cell has been the technique of cloning. (who.int)
  • The basic techniques of of the implanted nucleus, when it fully cloning have been known for some time, and develops. (who.int)
  • Nowadays we know that stem cells from adult tissues, as well as those associated with a live birth (such as the umbilical cord, placenta, amniotic fluid, etc.) are far more versatile than originally thought. (catholicphilly.com)
  • These procedures are likely to lead to an increase in international trafficking of human cells, eggs and embryos. (i-sis.org.uk)
  • Alternatively, research using eggs may point the way to methods which mimic their properties using other human cells and chemical agents. (spiked-online.com)
  • Verma said these cells can be used either for cloning or to grow eggs or sperm in a lab. (scientificamerican.com)
  • The cells could also be stored in cryopreservation for future use when eggs and sperm are too difficult to collect or freeze. (scientificamerican.com)
  • Three days ago the science journal Nature reported that mouse tissue cells in the US and Japan were turned into embryonic-type stem cells without the use of eggs or embryos. (freerepublic.com)
  • General Assembly the following year,3 and the World Medical Association's Resolution on Cloning, endorsed in 1997, have confronted the issue but lack binding legal force. (who.int)
  • In these experiments the germline transmission rate exceeded 65% for multiple tested clones. (umassmed.edu)
  • One of the 'restored' clones (JM8A3) showed particularly favorable results in blast injection experiments. (umassmed.edu)
  • The term applies not only to entire organisms but also to copies of molecules (such as DNA) and cells. (who.int)
  • Special emphasis will be placed on organisms with particular advantages for the study of embryonic development: e.g., mouse, frog, zebrafish, and Drosophila. (upenn.edu)
  • Unicellular for those cells that are derived from human organisms are primed to replicate (clone) pre-embryos, which seem to have a high themselves by nature. (who.int)
  • Fusion to the N-terminal part of GMNN provided tightly controlled mScarletI expression during the cell cycle. (bvsalud.org)
  • H2B-mTurquoise2 expression is absent but readily induced by doxycycline allowing quantification of cell divisions and imaging of living cells. (bvsalud.org)
  • Knowledge on the expression analysis of Notch signaling pathway molecules in SHED cultured in KGM could highlight its involvement in controlling the biological activity of these stem cells, particularly during odontogenesis and other developmental process. (bvsalud.org)
  • The process, they said, created stem cells that might be grown into healthy tissue to replace those of people with diabetes, Alzheimer's disease and other disorders. (blogspot.com)
  • The problem is that stem cells are currently sourced from human embryos, either from aborted fetuses (as in this case), or from blastocysts created by artificial insemination and grown in vitro specifically for the purpose. (blogspot.com)
  • Donor fibroblasts were obtained from an ear-skin biopsy of a male Afghan hound and cultured for two to five passages (in which fully grown cells are transferred to a new culture dish). (nature.com)
  • In addition to retinal cells, other stem-cell derivatives are likely to play an important role in the future of regenerative medicine. (news-medical.net)
  • These Outcomes are promising for regenerative medicine ill the therapy of diabetes mellitus, and clarification of the importance of selecting appropriate adult somatic cells in deriving identical ESC lines is also a significant step. (yildiz.edu.tr)
  • If it can be produced in sufficient quantity this source of 'normal' human tissue could be of major importance to the pharmaceutical industry for drug screening. (spiked-online.com)
  • Current screening of potential new drugs is done using cell lines derived from animals or 'abnormal' human tissue such as tumor cells. (spiked-online.com)
  • In a study published in the online journal Nature on March 1, 2009, Canadian researches described a new method for generating stem cells from adult human tissue. (cbc.ca)
  • We tested whether the cloned dogs were genetically identical by microsatellite analysis of genomic DNA from the donor Afghan, the cloned dogs and the surrogates (see supplementary information ). (nature.com)
  • Analysis of eight canine-specific microsatellite loci confirmed that the cloned dogs were genetically identical to their donor dog. (nature.com)
  • The term "clone", from the Greek word for twig, denotes a group of identical entities. (who.int)
  • In sexual reproduction, clones are created when a fertilized egg splits to produce identical (monozygous) twins with identical genomes. (who.int)
  • Beyond this scientific interest, the commercial concern in animal cloning focuses on replicating large numbers of genetically identical animals, especially those derived from a progenitor that has been modified genetically. (who.int)
  • If the clone had been allowed to continue beyond implantation it would have developed as Dr Cibelli's identical twin. (globalchange.com)
  • The word "cloning" refers to a variety of procedures that may be used to create biological copies that are genetically identical to the original. (geminigenetics.com)
  • Pet cloning is the process where a genetically identical twin is created of your original animal companion. (geminigenetics.com)
  • But they showed, for the first time, that it is possible to create cloned embryonic stem cells that are genetically identical to the person from whom they are derived. (nationalrighttolifenews.org)
  • Moreover, the field is only inching forward scientifically as it is proving very hard to harness cells meant to create differentiated tissues in gestating embryos and fetuses. (nationalrighttolifenews.org)
  • Finally, and inexorably, a true professional scientist poses clearly challenging questions to his research colleagues, and to the scientific enterprise in general, about the dubious "scientific" justification for the current rush to clone human beings - for both "therapeutic" and for "reproductive" purposes. (lifeissues.net)
  • WHA50.37 of 1997 argues that human cloning is ethically unacceptable and contrary to human integrity and morality. (who.int)
  • fication and isolation via fluorescence-activated cell sort- ing (FACS). (lu.se)