Primary tumor tissues of lung adenocarcinoma (ADC) ( n = 26) and squamous cell carcinoma (SQCC) ( n = 18) obtained from surgery were assigned to subgroups according to the patient's smoking status. (biomedcentral.com)
Extracted lipids from the tumor tissues were subjected to liquid chromatography-tandem mass spectrometry analysis. (biomedcentral.com)
Most of them generally follow the same pathway to make immune-activated cytotoxic T lymphocytes (CTLs) abundantly infiltrate into tumor tissues and destroy tumor cells [ 6 ]. (thno.org)
Uracil2
Maintenance treatment of Uracil and Tegafur (UFT) in responders following first-line fluorouracil-based chemotherapy in metastatic gastric cancer: a. (oncotarget.com)
The purpose of this phase II study was to evaluate the efficacy and safety of Uracil and Tegafur (UFT) maintenance in metastatic gastric cancer patients following the first-line fluorouracil-based chemotherapy. (oncotarget.com)
Capecitabine1
gene, is the initial and rate-limiting enzyme of the metabolic pathway of fluoropyrimidines, such as 5-Fu, capecitabine and tegafur [6C8]. (insulin-receptor.info)
Bone tissue marrow3
Furthermore, in lethally-irradiated Compact disc45.1+ B6.SJL mice reconstituted using a 1:1 Tegafur combination of bone Tegafur tissue marrow cells from B6.SJL and mice the amounts of follicular B cells due to the cKO bone tissue marrow weren't reduced in Tegafur comparison to those due to B6.SJL bone tissue marrow (Data not proven). (tech-strategy.org)
Thymus function is usually considered to depend in a steady way to obtain T cell progenitors in the bone tissue marrow. (biongenex.com)
Nevertheless we discovered no proof for export of donor HSCs from thymus to bone tissue marrow. (biongenex.com)
Biomarkers1
Specific lipids in cancer tissues have been reported as potential biomarkers reflecting patient prognosis and the risk of postoperative recurrence. (biomedcentral.com)
Mice4
PTBP2 partially compensates for the loss of PTBP1 in GC B cells The manifestation of PTBP2 in solitary and double conditional knockout (dcKO) Tegafur mice. (tech-strategy.org)
double bad [DN]) 3 (CD4?CD8?CD25and (component of the IL-7 receptor) double-deficient mice are completely devoid of Tegafur T cell progenitors including the earliest phases (Rodewald et al. (biongenex.com)
2009 These mice have no endogenous T cell development because Tegafur of the lack of Kit and IL-7R function in their bone marrow progenitors. (biongenex.com)
In contrast even at later times in mice Tegafur a large proportion of cells were of donor thymus origin and overall donor cell numbers although heterogeneous between grafts were on average several orders of magnitude higher in compared with hosts (Fig. 1 B). Figure 1. (biongenex.com)
Injection1
The authors developed a high-performance liquid chromatography (HPLC) assay for the determination of tissue or plasma tegafur and 5-FU concentration in a single step extraction and a single HPLC injection. (cun.es)
Differentiation1
The PSK-reactive group demonstrated no relation to the age and sex of the patients, tissue differentiation type or tumor advancement. (unboundmedicine.com)
Organs1
Carcinomas tend to invade nearby tissue and spread (metastasize) to distant organs such as the liver, lungs, bone, and brain. (bioresonancetherapy.com.sg)
Lung1
Because cigarette smoking and oncogenesis alter lipid metabolism in lung tissue, we hypothesized that the lipid profiles in lung cancer tissues are influenced by cigarette smoking and can reflect the postoperative recurrence risk in smoking lung cancer patients. (biomedcentral.com)
Times1
The retention times of 5-FU and tegafur were 5 and 16.5 minutes, respectively, and the internal standard retention times were 11.5 and 17.5 minutes for 5-bromouracil (5-BU) and beta-hydroxyethyltheophylline, respectively. (cun.es)
Patients1
Inside our present research, 5 SNPs position (c.74A G, c.85T C, c.1627A G, c.1896T C, c.2194G A) were detected in tumor tissue from 331 intrusive breast cancer patients. (insulin-receptor.info)
Findings1
These findings on isotopic 13C discrimination during microbial degradation both of simple biochemical compounds and of complex vegetal tissue confirmed not only the existence of significant 13C isotopic fractionation during plant residue decomposition, but also the existence of non-random isotopic distribution within substrates. (mushroomstudies.co)
Cancer1
The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. (oncotarget.com)
Spread1
Abiraterone Acetate works by blocking the production of Testosterone and results in slowing down the spread and growth of cancerous tissue. (theindianpharma.com)
Doxorubicin3
It has been shown that the breast cancer is sensitive to the most anti-tumour medicines, especially to doxorubicin and epirubicin (efficacy in 40-50% of patients with the metastatic breast cancer), methotrexate (efficacy in 35% of patients), fluorouracil and tegafur (efficacy in 25-34% of patients). (crimsonpublishers.com)
C167080 SEER Rx Interactive Antineoplastic Drugs Database-Regimen C161966 ACFTOR-BCG Regimen FAC-BCG A chemotherapy regimen consisting of tegafur, doxorubicin, cyclophosphamide, and Bacillus Calmette-Guerin (BCG) that may be used in the treatment of breast cancer. (nih.gov)
C167080 SEER Rx Interactive Antineoplastic Drugs Database-Regimen C63516 AD Regimen AD A regimen consisting of doxorubicin and dacarbazine used for the treatment of unresectable soft tissue sarcoma. (nih.gov)
Tumor tissue1
11. Predictive value of dihydropyrimidine dehydrogenase expression in tumor tissue, regarding the efficacy of postoperatively administered UFT (Tegafur + Uracil) in patients with p-stage I nonsmall-cell lung cancer. (nih.gov)
Fluorouracil2
In addition to 5-fluorouracil, oral fluoropyrimidines such as capecitabine (Xeloda) and, outside the United States, tegafur are used as monotherapy or in combination with oxaliplatin (Eloxatin). (medscape.com)
Undergoes hydrolysis in liver and tissues to form the active moiety (fluorouracil), inhibiting thymidylate synthetase, which in turn blocks methylation of deoxyuridylic acid to thymidylic acid. (medscape.com)
Thymidylate1
8. [Drug concentration in cancerous large bowel tissue and thymidylate synthase inhibition rate after administration of tegafur and UFT]. (nih.gov)
Liver1
15. Oral administration of uracil-tegafur (UFT) inhibits liver micrometastasis of human colon cancer in an orthotopic nude mouse model and its early detection system. (nih.gov)
Oral2
Forty-five patients received no treatment and 22 patients received oral administration of UFT, a combination of Uridine and Tegafur, before surgery. (nih.gov)
9. [Level of 5-FU in tumor tissues of the patients with head and neck malignant tumors after oral administration of UFT]. (nih.gov)
Administration1
For Teysuno (tegafur/gimeracil/oteracil) capsules Indications And Usage, Dosage And Administration, Dosage Forms And Strengths and Drug Interactions. (alleviareindia.com)
Modified HPV particles may be used for the treatment of diseases or conditions of mucosal tissue, including HPV (human papilloma virus) infection and HPV-related tumors. (justia.com)
2. Antitumor activity of 1 M tegafur-0.4 M 5-chloro-2,4-dihydroxypyridine-1 M potassium oxonate (S-1) against human colon carcinoma orthotopically implanted into nude rats. (nih.gov)
10. L.C.Tsai, Jen-Kou Lin, S.H.Han, H.M.Chen:Suppression of the growth of human colorectal carcinoma cells (LS174T) by radiolabeled monoclonal antibody(131I-MAbC27) in tissue culture and nude mice. (joshua-healthcare.com)
Medicine1
This medicine is an anticonvulsant that works in the brain tissue to stop seizures. (drugs.com)