InsulinInsulin ResistanceGlucose Clamp TechniqueAdipose TissueReceptor, InsulinGlucoseBlood GlucoseGlucose Tolerance TestLiverObesityMuscle, SkeletalInsulin Receptor Substrate ProteinsInsulin, Long-ActingInsulin AntibodiesHypoglycemic AgentsInsulin AntagonistsIslets of LangerhansInsulin LisproDiabetes Mellitus, Type 2Insulin Infusion SystemsInsulin AspartInsulin, IsophaneInsulin, Regular, PorkHyperinsulinismInsulin-Secreting CellsInsulinsGlucagonInsulin, Regular, HumanC-PeptideProinsulinFastingHyperglycemiaDiabetes Mellitus, Type 1Signal TransductionFatty Acids, NonesterifiedGlucose Transporter Type 4AdipocytesInsulin, Short-ActingHypoglycemiaPhosphorylationDiabetes Mellitus, ExperimentalDiabetes MellitusGlucose IntoleranceInsulin-Like Growth Factor ILeptinDeoxyglucoseBody WeightTriglyceridesPhosphoproteinsMonosaccharide Transport ProteinsPhosphatidylinositol 3-KinasesInsulinomaCells, CulturedBiphasic InsulinsKineticsProto-Oncogene Proteins c-aktHemoglobin A, GlycosylatedGlycogenHomeostasisAdiponectinPostprandial PeriodRats, WistarLipidsTime FactorsPancreasGlucagon-Like Peptide 1Cell LineBody Mass IndexMetforminDietary FatsDose-Response Relationship, DrugMice, ObeseLipid MetabolismRNA, MessengerRats, Inbred StrainsThiazolidinediones3T3-L1 CellsLipolysisMuscle ProteinsRats, Sprague-DawleyReceptor, IGF Type 1Rats, ZuckerMice, Inbred C57BLMetabolic Syndrome XTolbutamideInfusions, SubcutaneousEatingDietary CarbohydratesGene Expression RegulationBody CompositionBiological TransportDiet, High-FatReference ValuesStreptozocinMice, KnockoutEnergy MetabolismGlycogen SynthaseSomatostatinAdiposityGluconeogenesis