• Although previous recommendations for preventing transmission of human immunodeficiency virus (HIV) through transplantation of human tissue and organs have markedly reduced the risk for this type of transmission, a case of HIV transmission from a screened, antibody-negative donor to several recipients raised questions about the need for additional federal oversight of transplantation of organs and tissues. (cdc.gov)
  • A working group formed by the Public Health Service (PHS) in 1991 to address these issues concluded that further recommendations should be made to reduce the already low risk of HIV transmission by transplantation of organs and tissues. (cdc.gov)
  • This occurrence raised questions about the need for additional federal oversight of transplantation of organs and tissues. (cdc.gov)
  • The working group concluded that, although existing recommendations are largely sufficient, revisions should be made to reduce the already low risk of HIV transmission via transplantation of organs and tissues. (cdc.gov)
  • However, Kenya has already drafted new legislation which covers the donation of organs and tissues from both living and deceased donors, and eight Member States8 intend to adopt new legal requirements. (who.int)
  • Through biofabrication, we are advancing scaffold technologies in both cardiac tissue engineering and organs-on-a-chip using these new materials. (utoronto.ca)
  • Cardiac tissue bioengineering represents an important research direction for the patient-specific myocardial reconstruction therapies. (romanianjournalcardiology.ro)
  • Tridimensional cardiac tissues generation requires a structural matrix, specialized cardiac cells and an optimal medium in which cells can multiply and form a mature tissue, capable of sustaining the complex cardiac functions. (romanianjournalcardiology.ro)
  • To obtain functional cardiac tissue on a rat animal model, starting with a decellularized heart used as a matrix for grafting the human cells- adult mesenchymal stem cells (MSC) and induced pluripotent stem cells (iPSC) obtained through peripheral blood lymphocytes T transduction. (romanianjournalcardiology.ro)
  • Recellularization was performed on decellularized cardiac tissue fragments and in 3 D models, throu-gh intraventricular injection or aortic perfusion with myocardial cells. (romanianjournalcardiology.ro)
  • Fatty acids are taken up by muscle and cardiac tissue as a fuel source, and glycerol is taken up by the liver for gluconeogenesis. (wikipedia.org)
  • Taken together, CITED4 expression is necessary for exercise-induced regional remodeling of the heart's microstructural helicity revealing how a key molecular regulator of cardiac remodeling manifests into downstream local tissue-level changes. (researchgate.net)
  • Expression of transcription factor CITED4 is necessary for exercise-induced regional remodeling of the heart's microstructural helicity, revealing how a key molecular regulator of cardiac remodeling mediates local tissue-level changes. (researchgate.net)
  • Due to their large surface area and ability to interact with proteins and peptides, graphene oxides offer valuable physiochemical and biological features for biomedical applications and have been successfully employed for optimizing scaffold architectures for a wide range of organs, from the skin to cardiac tissue. (mdpi.com)
  • Thymus tissue is obtained from donors less than or equal to 9 months of age undergoing cardiac surgery. (rxlist.com)
  • Magnetic resonance imaging (MRI) is a powerful noninvasive imaging modality that produces images with excellent soft tissue signal and tunable contrast. (purdue.edu)
  • Most groups 3D print structures from hydrogels, which deform as a result of cell tractional forces, or rigid polymers, which are too stiff for soft tissue applications. (utoronto.ca)
  • We are pioneering 3D printing of designer elastic biopolymers to create versatile granular and metamaterial structures for applications in soft tissue engineering. (utoronto.ca)
  • December 21, 2015 - NIH findings with potential for enhancing human health include advances in Ebola research, progress in fighting HIV, and the development of custom 3-D printed nerve scaffolds to aid tissue regeneration. (nih.gov)
  • The transplant, a donor tissue from the network of the German Society for Tissue Transplantation ( DGFG ), had to be delivered quickly: Within 24 hours, the heart valve from the tissue bank in Kiel had to reach the hospital in Brasov for implantation. (gewebenetzwerk.de)
  • The Polisano Fundatia Foundation from Sibiu, founded by Prof. Costache, also provided support in organising the transplantation in Brasov: "There is no infrastructure for tissue donation and transplantation in Romania. (gewebenetzwerk.de)
  • Organ and tissue donation and transplantation is a medical procedure in which an organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ or tissue. (who.int)
  • There is no information about reproductive tissue transplantation as a method of treating infertility in the African Region. (who.int)
  • https://en.wikipedia.org/wiki/Organ_transplantation. (who.int)
  • 4 World Health Assembly - Resolution WHA63.22 on Human organ and tissue transplantation, May 2010. (who.int)
  • This confocal microscopic image shows tissue-engineered human stomach tissues from the corpus/fundus region, which produce acid and digestive enzymes. (sciencebulletin.org)
  • Scientists report in Nature using pluripotent stem cells to generate human stomach tissues in a petri dish that produce acid and digestive enzymes. (sciencebulletin.org)
  • Reprogramming of antral stomach cells assembled into bioengineered mini-organs in vitro yielded transplantable units that also suppressed hyperglycemia in diabetic mice, highlighting the potential for development of engineered stomach tissues as a renewable source of functional β cells for glycemic control. (diabetesresearchconnection.org)
  • Injectable Peptide Decorated Functional Nanofibrous Hollow Microspheres to Direct Stem Cell Differentiation and Tissue Regeneration. (stembook.org)
  • We are advancing our peptide based biomimetic and immunomodulatory materials for regeneration of tissues such as skin and immune system. (utoronto.ca)
  • However, to fulfill this promise, a remaining challenge is to induce human iPSC to recreate in vitro key structural and functional features of the native retina, in particular the presence of photoreceptors with outer-segment discs and light sensitivity. (nature.com)
  • Altogether, this approach can enable a functional and structural investigation of subcellular features in the context of cells and tissues. (ucl.ac.uk)
  • Extracellular matrix is a fibrillar network composed of structural (collagens) and adhesion (fibronectin) proteins crucial for tissue architecture and biological pathway Histol Histopathol 27:1515-1528, 2012 . (springer.com)
  • Twelve weeks later, the tissue had successfully grown to reveal nephrons, the structural elements found inside a working human kidney. (newatlas.com)
  • This review critically focuses on opportunities to employ protein-graphene oxide structures either as nanocomposites or as biocomplexes and highlights the effects of carbonaceous nanostructures on protein conformation and structural stability for applications in tissue engineering and regenerative medicine. (mdpi.com)
  • With such issues in mind, recent research has focused on possible solutions for the lack of access to donor organs and rejections, with the possibility of using the patient's own cells and tissues for treatment showing enormous potential. (psu.edu)
  • The manufacturing process preserves the thymic epithelial cells and tissue structure and depletes most of the donor thymocytes from the tissue. (rxlist.com)
  • The family could not have afforded the surgery - and the local doctors lack clinical know-how and donor tissue. (gewebenetzwerk.de)
  • We put him on our waiting list and were quickly able to find a suitable donor tissue for him," says Martin Börgel, managing director of DGFG. (gewebenetzwerk.de)
  • A 1991 investigation determined that several recipients had been infected with HIV by an organ/tissue donor who had tested negative for HIV antibody at the time of donation (4). (cdc.gov)
  • Using these approaches we developed technologies such as Injectable Tissue, that enable non-invasive delivery of fully functional tissues into the body through a keyhole and Hook-in-Tissues which enable stacking and instantaneous assembly of fully functional tissues. (utoronto.ca)
  • Hidden fields are included for Core name, College and functionality state (fully functional, partially functional, non functional, on repair). (sc.edu)
  • The idea to use transplants of dopa- ment of protocols that allow generation of fully functional mine-producing cells to substitute for the lost midbrain and safe midbrain dopamine neurons from stem cells. (lu.se)
  • Objective: β-adrenoceptor mediated activation of brown adipose tissue (BAT) has been associated with improvements in metabolic health in models of type 2 diabetes and obesity due to its unique ability to increase whole body energy expenditure, and rate of glucose and free fatty acid disposal. (monash.edu)
  • Previously, we showed that exosomes derived from human adipose tissue-derived mesenchymal stem cells (ASC-exosomes) attenuate AD-like symptoms by reducing multiple inflammatory cytokine levels. (mdpi.com)
  • Obesity is defined as an excess accumulation of white adipose tissue associated with a low grade inflammation which is one contributor to obesity complications such as diabetes. (springer.com)
  • Recently, we and others have demonstrated fibrotic depots in white adipose tissue of obese subjects. (springer.com)
  • In the first one, local adipose tissue hypoxia could induce fibrosis accumulation which in turn through adipocyte dysfunctions might provoke adipose tissue inflammation. (springer.com)
  • In the second one, fibrosis could be a result of local adipose tissue inflammation induced by tissue expansion. (springer.com)
  • However many more pro and anti-inflammatory mediators produced by the adipose tissue have been described since then. (springer.com)
  • An increase in adipogenic differentiation levels was accompanied by an upregulation of the expression levels of several adipogenic genes including peroxisome proliferator-activated receptor gamma ( PPAR γ ), adipocyte protein 2 ( AP2 ), adipose tissue-specific secretory factor ( ADSF ), sterol regulatory element-binding protein 1C ( SREBP1C ), lipoprotein lipase ( LPL ), adiponectin ( ADIPOQ ), and glucose transporter type 4 ( GLUT4 ) [ 8 , 9 , 11 ]. (hindawi.com)
  • White adipose tissue or white fat is one of the two types of adipose tissue found in mammals. (wikipedia.org)
  • The other kind is brown adipose tissue. (wikipedia.org)
  • White adipose tissue is composed of monolocular adipocytes. (wikipedia.org)
  • In humans, the healthy amount of white adipose tissue varies with age, but composes between 6-25% of body weight in adult men and 14-35% in adult women. (wikipedia.org)
  • White adipose tissue is used for energy storage. (wikipedia.org)
  • There is actually no evidence at present that glucagon has any effect on lipolysis in white adipose tissue. (wikipedia.org)
  • The trigger for this process in white adipose tissue is instead now thought to be adrenocorticotropic hormone, adrenaline and noradrenaline[citation needed]. (wikipedia.org)
  • White adipose tissue also acts as a thermal insulator, helping to maintain body temperature. (wikipedia.org)
  • The hormone leptin is primarily manufactured in the adipocytes of white adipose tissue which also produces another hormone, asprosin. (wikipedia.org)
  • White adipose tissue is most abundant in mammals and its distribution greatly varies among different species. (wikipedia.org)
  • Usually white adipose tissue can be found in two different locations of the body where it is stored: subcutaneous adipose tissue and intra-abdominal adipose tissue. (wikipedia.org)
  • Subcutaneous adipose tissue is directly underneath the skin, while the intra-abdominal adipose tissue surrounds the organs inside the abdomen such as intestine and kidneys. (wikipedia.org)
  • The visceral adipose tissue is part of the intra-abdominal adipose tissue that surrounds the intestine for the most part. (wikipedia.org)
  • White adipose tissue exists mostly as a single adipocytes in the subcutaneous tissue. (wikipedia.org)
  • In humans, white adipose tissue starts to develop during early to mid-gestation period. (wikipedia.org)
  • White adipose tissue consists of white adipocytes, which are the lipid storage cells. (wikipedia.org)
  • White adipose tissue exists in various depots that may have different types of adipocytes. (wikipedia.org)
  • This led to various theories to find the adipogenic lineage of the white adipose tissue depots. (wikipedia.org)
  • To begin, place the desired segments of intestinal tissue collected from claudin-15 knockout mice into ice cold bubbled Ringer's solution and trim away the fat and connective tissue. (jove.com)
  • After trimming away the fat and connective tissue, cut along the mesenteric attachments to open each segment longitudinally, then return the segments to the ice cold Ringer's solution and wash the pieces thoroughly. (jove.com)
  • We examined the pattern and extent of connective tissue distribution in the extraocular muscles (EOMs) and determined the ability of the interconnected connective tissues to disseminate force laterally. (umn.edu)
  • Connective tissue distribution was examined with scanning electron microscopy. (umn.edu)
  • A striking connective tissue matrix interconnects all the myofibers and extends, via perimysial connections, to the epimysium. (umn.edu)
  • We then sought to address specificity of MIG expression, minor intron retention, and alternative splicing (AS) across mouse and human tissues. (biomedcentral.com)
  • We then analyzed the RNAseq data from eleven different mouse tissues, which revealed tissue-specific MIG expression and minor intron retention. (biomedcentral.com)
  • Functional studies revealed increased expression of ICAM-1 on induced patient-derived endothelial cells (iECs) and of β2-integrins on patient neutrophils that increase neutrophil adhesion and vascular transendothelial migration (TEM). (nature.com)
  • De- cidual cells promote hemostasis through enhanced expression of tissue factor (TF), the primary initiator of hemostasis via thrombin generation, and plasminogen activator inhibitor-1, which inactivates tissue type plasminogen activator, the primary fibrinolytic agent. (scirp.org)
  • 2009) Progestin and thrombin regulate tissue factor expression in human term decidual cells. (scirp.org)
  • Quantification of CITED4 expression and microstructural tissue helicity reveals a significant correlation across both sedentary and exercise mouse cohorts. (researchgate.net)
  • Native antral endocrine cells share a surprising degree of transcriptional similarity with pancreatic β cells, and expression of β cell reprogramming factors in vivo converts antral cells efficiently into insulin+ cells with close molecular and functional similarity to β cells. (diabetesresearchconnection.org)
  • The Multiple Species Tissue Array (MSTA) slides were designed to study protein expression patterns in different cells and tissues from multiple species. (prosci-inc.com)
  • Most tumor -infiltrating CD8+CD103+ TRMs are CD45RA-CCR7- effector- memory cells with higher PD-1 and 4-1BB expression than those from non- tumor tissues . (bvsalud.org)
  • Genetic and functional expression, respectively. (cdc.gov)
  • The advent of new methods to obtain large-scale surveys of various mathematical structures, such as systems of differen- gene expression in which transcript levels can be determined tial equations, graphical networks, stochastic functional re- for thousands of genes simultaneously has facilitated the ex- lations, and simulation models. (lu.se)
  • Central to this movement is an ap- damental issues of expression-based functional genomics. (lu.se)
  • to confirm tissue viability is also an important step. (jove.com)
  • The Tissue Viability Service is a nurse led support and advisory service providing specialist advice and care to patients with, or at risk of developing wounds. (nhsforthvalley.com)
  • Not all patients who have a wound will require specialist advice from the Tissue Viability Service. (nhsforthvalley.com)
  • The Tissue Viability Service can be accessed via patients GP, District Nurse, Practice Nurse, Podiatrist, Acute and Community Hospital Staff, Medical Staff and Care Home Trained staff. (nhsforthvalley.com)
  • With the patients consent then the above professionals will refer to the Tissue Viability service completing appropriate referral, to obtain specialist advice and support. (nhsforthvalley.com)
  • Patients may be seen in the Tissue Viability Clinic, their own home (if housebound)/care home, hospital ward or their local GP practice Treatment Room. (nhsforthvalley.com)
  • Specialist wound care/Tissue Viability advice is also given to healthcare staff via telephone and email. (nhsforthvalley.com)
  • NB The Tissue Viability Service does not operate a self referral service for members of the public. (nhsforthvalley.com)
  • Major progress has been made in recent years to produce functional insulin+ cells for cell replacement therapies to treat diabetes. (diabetesresearchconnection.org)
  • Current treatments for acute ischemic stroke include IV thrombolytic therapy with tissue-type plasminogen activator ( t-PA ) and endovascular therapies using stent retriever devices. (medscape.com)
  • Understanding the function of biological tissues requires a coordinated study of physiology and structure, exploring volumes that contain complete functional units at a detail that resolves the relevant features. (ucl.ac.uk)
  • Functional networks, where the interactions are quantified by their probability of being involved in the same biological process are typically generated at the gene level. (figshare.com)
  • The extracellular matrix is essential for the architecture of the tissue and a myriad of associated biological functions. (springer.com)
  • Although the effects of high glucose on the proliferation and differentiation of rat and mouse BM-MSCs have been previously reported, the effects of high glucose on biological properties of human MSCs derived from gestational tissues which, due to their ease of isolation by noninvasive procedure, are considered more suitable sources of MSCs for clinical applications have yet to be determined. (hindawi.com)
  • Biological and functional effects of repeated vibration exposures in muscle tissue. (cdc.gov)
  • The twin aims of tissue classification and pathway mod- in the context of larger molecular networks. (lu.se)
  • However, many problems must be overcome before the generation of functional tissues with biologically-relevant scale is possible. (psu.edu)
  • Here, we introduce an approach to address this challenge: Mouse brain tissue sections containing a region where function was recorded using in vivo 2-photon calcium imaging were stained, dehydrated, resin-embedded and imaged with synchrotron X-ray computed tomography with propagation-based phase contrast (SXRT). (ucl.ac.uk)
  • A research team at Tianjin University (TJU) has achieved the first "True Perspective" imaging of the optical function of in vivo deep tissue using a quantitative optoacoustic method based on deep learning. (tju.edu.cn)
  • rECM has rheological and gelation properties beneficial for 3D bioprinting while retaining biologically inductive properties supporting tissue maturation ex vivo and in vivo. (lu.se)
  • Here we have succeeded in inducing human iPSC to recapitulate the main steps of retinal development and to form fully laminated 3D retinal tissue by exploiting the intrinsic cues of the system to guide differentiation ( Supplementary Fig. 1 ). (nature.com)
  • Human proximal tubule cells adhere to the hollow channel, forming a functional, 3D renal architecture. (harvard.edu)
  • Now, in close collaboration with Roche scientist Annie Moisan, they have leveraged their bioprinting and materials expertise to construct a functional 3D renal architecture containing living human epithelial cells, which line the surface of tubules in the kidney. (harvard.edu)
  • The current work further expands our bioprinting platform to create functional human tissue architectures with both technological and clinical relevance," said Lewis. (harvard.edu)
  • BOSTON) - Toward the ultimate goal of engineering human tissues and organs that can mimic native function for use in drug screening, disease modeling, and regenerative medicine, a Wyss Institute team led by Core Faculty member Jennifer Lewis, Sc.D., has made another foundational advance using three-dimensional (3D) bioprinting. (harvard.edu)
  • The current work further expands our bioprinting platform to create functional human tissue architectures with both technological and clinical relevance," said Lewis, who is also the Hansjörg Wyss Professor of Biologically Inspired Engineering at the Harvard John A. Paulson School of Engineering and Applied Sciences. (harvard.edu)
  • The use of functional tissue-like models during pre-clinical studies will provide unprecedented insights into human-relevant drug response prior to clinical development," said Moisan, a Laboratory Head in Mechanistic Safety at Roche and author of this study. (harvard.edu)
  • As a fabrication platform, the approach is flexible, scalable, and adaptable, meaning that in addition to working towards larger, scaled-up kidney constructs, the team also plans to explore development of other types of complex functional human tissues and organs. (harvard.edu)
  • Finally, we identified several novel AS events across minor introns in both mouse and human, which were also tissue-dependent. (biomedcentral.com)
  • December 7, 2015 - Researchers grew human cells into functional vocal cord tissue in the laboratory-an important preliminary step toward restoring voice function to people with injured vocal cords. (nih.gov)
  • Federal regulations specify there can be "reasonable payments associated with the transportation, implantation, processing, preservation, quality control, or storage of human fetal tissue. (religionnews.com)
  • For the first time, scientists have successfully grown functioning human kidney tissue in the lab that is able to produce urine. (newatlas.com)
  • The kidney tissue, generated from human stem cells, was implanted under the skin of mice and went on to develop into working kidney cells. (newatlas.com)
  • This remarkable advance brings medicine one step closer to being able to either repair or replace damaged kidney tissue in human beings by growing a functioning organ from stem cells. (newatlas.com)
  • However, the effect of high glucose on adipogenic differentiation of human bone marrow and gestational tissue-derived MSCs is still poorly characterized. (hindawi.com)
  • This study aims to investigate the effects of high glucose on proliferation as well as adipogenic and osteogenic differentiation of human MSCs derived from bone marrow and several gestational tissues including chorion, placenta, and umbilical cord. (hindawi.com)
  • tissue-resident memory T cells in human gastric cancer. (bvsalud.org)
  • Distribution, phenotype, functional and clinical relevance of CD8 + CD103 + tissue-resident memory T cells in human gastric cancer. (bvsalud.org)
  • CD8+CD103+ tissue -resident memory T cells (TRMs) are involved in tumor immune response and linked to favorable clinical outcome in human cancer . (bvsalud.org)
  • Recent advances in 3D bioprinting allow for generating intricate structures with dimensions relevant for human tissue, but suitable bioinks for producing translationally relevant tissue with complex geometries remain unidentified. (lu.se)
  • Their proof-of-principle for generating human tissue is demonstrated by 3D bioprinting human airways composed of regionally specified primary human airway epithelial progenitor and smooth muscle cells. (lu.se)
  • rECM bioinks are a promising new approach for generating functional human tissue using 3D bioprinting. (lu.se)
  • This work builds upon their demonstrated ability to bioprint tissue constructs composed of multiple types of living cells patterned alongside a vascular network in an extracellular matrix. (harvard.edu)
  • The Harvard team has also previously shown that these constructs could be scaled up to create thick, vascularized tissue constructs, sustained viable for more than a month in vitro . (harvard.edu)
  • Bioprinting offers the means of utilizing a patient's cells to design and fabricate constructs for replacement of diseased tissues and organs. (psu.edu)
  • Obesity is defined as an expansion of white adipose (WAT) tissue that is associated with low grade inflammation which possibly contributes to the development of health complications such as diabetes, liver pathologies, dyslipidemia, cardiovascular diseases as well as some cancers [ 2 - 4 ]. (springer.com)
  • Can 3D imaging modeling recognize functional tissue and predict liver failure? (biomedcentral.com)
  • However, it is still unclear to what extent hiPSC may be capable of recapitulating in vitro the cellular and molecular features of the native retina, especially regarding photoreceptor differentiation and functional maturation. (nature.com)
  • However, the regional microstructural tissue effects of these molecular mechanisms in the heart have yet to be spatially linked and further elucidated. (researchgate.net)
  • Adipocytes in the accumulated fat tissues, especially around waist area and visceral organs, release several cytokines which reduce the sensitivity of several cell types to insulin leading to insulin resistant and type 2 diabetes [ 4 , 5 ]. (hindawi.com)
  • Moreover, the photoreceptors in our hiPSC-derived retinal tissue achieve advanced maturation, showing the beginning of outer-segment disc formation and photosensitivity. (nature.com)
  • In this perspective, this paper discusses the challenges of functionalization of bioprinted tissue under eight dimensions: biomimicry, cell density, vascularization, innervation, heterogeneity, engraftment, mechanics, and tissue-specific function, and strives to inform the reader with directions in bioprinting complex and volumetric tissues. (psu.edu)
  • For this purpose, this paper discusses several factors that are critical for printing functional tissues including cell density, vascularization, innervation, heterogeneity, engraftment, mechanics, and tissue-specific function, and inform the reader with future directions in bioprinting complex and volumetric tissues. (psu.edu)
  • Mononuclear phagocytes: tissue distribution and functional heterogeneity. (ox.ac.uk)
  • Lewis' team achieved this advance by adapting their earlier approach for bioprinting living cells to form thick tissues. (harvard.edu)
  • Nutrients, which perfuse the tubule through the inlet and outlet, nourish the living cells and a keep them alive and functional for more than two months. (harvard.edu)
  • pathomechanisms that regulate extravasation of damaging immune cells into surrounding tissues are poorly understood. (nature.com)
  • Tissue infiltration by activated innate immune cells, including monocytes, macrophages, and neutrophils, if untreated, leads to rapidly progressive organ injury, that can involve many organ systems. (nature.com)
  • The gastrointestinal (GI) epithelium is a highly regenerative tissue with the potential to provide a renewable source of insulin+ cells after undergoing cellular reprogramming. (diabetesresearchconnection.org)
  • Here, we show that cells of the antral stomach have a previously unappreciated propensity for conversion into functional insulin-secreting cells. (diabetesresearchconnection.org)
  • The gastrointestinal (GI) tissues are potential sources for such continued generation of β cells. (diabetesresearchconnection.org)
  • We sought to devise improved strategies to derive functional insulin-secreting (insulin+) cells from GI tissues and to harness the regenerative capacity of these tissues as a renewable source of β cells. (diabetesresearchconnection.org)
  • However, the distribution, phenotype , functional properties and clinical relevance of these cells in gastric cancer (GC) remain elusive. (bvsalud.org)
  • The result is functional mosaicism of cells. (medscape.com)
  • Tissues in which cells select for the defective PORCN gene show anomalies. (medscape.com)
  • As a consequence, certain tissues might be more susceptible to loss of minor spliceosome function. (biomedcentral.com)
  • Tissue slices from three different species are mounted on each MSTA slide which can then be treated as a single histological slide for H&E staining, immunohistochemistry, or in situ hybridization. (prosci-inc.com)
  • RETHYMIC consists of yellow to brown slices of allogeneic processed thymus tissue for administration by surgical implantation. (rxlist.com)
  • This thymus tissue is aseptically processed and cultured for 12 to 21 days to produce RETHYMIC slices. (rxlist.com)
  • Specific focus on the functionality of bioprinted tissues is required prior to clinical translation. (psu.edu)
  • Sandrine is still offering deep tissue massage but her emphasis is more and more on the abdominal, the seat of the body, for women, the womb being the inner compass. (thelifecentre.com)
  • The intra-abdominal adipose tissues covers the thoracic and abdominal cavity. (wikipedia.org)
  • Combined with contrast agents and image processing, spectral CT images can provide quantitative mappings of materials of interest inside a tissue. (purdue.edu)
  • This method will provide a high spatial resolution quantitative imaging strategy for obtaining images of blood oxygen characteristics related to the physiology and pathology of living tissues. (tju.edu.cn)
  • After getting her first qualification in Swedish massage she went on learning more skills fromThai Massage, Tui Na, Deep tissue, Pregnancy, Thai Foot Massage, Indian Head Massage and more than 12 years ago Chi Nei Tsang learned both in Thailand and Guatemala. (thelifecentre.com)
  • Deep tissue massage helps you to get to the root of intense or long standing pain and bring health and healing. (thelifecentre.com)
  • QOAT can directly obtain the optical absorption coefficient images of deep tissue and has drawn attention from research institutions and medical enterprises both in China and worldwide. (tju.edu.cn)
  • Optoacoustic imaging cannot truly reflect the optical absorption coefficient of tissue due to the light intensity attenuation in deep tissue, negatively affecting the accuracy and reliability of deep tissue imaging. (tju.edu.cn)
  • However, in many biomedical imaging methods, it is difficult to obtain the true values of deep tissue, especially those of living tissue. (tju.edu.cn)
  • Current state-of-the-art experimental and computational proteomic approaches were integrated to obtain a comprehensive protein profile of Populus vascular tissue. (doe.gov)
  • Bioinformatics analysis revealed that several of the AS events could result in the production of novel tissue-specific proteins. (biomedcentral.com)
  • Fibrosis is characterized by an excessive accumulation of extracellular matrix components which could result in tissue dysfunction. (springer.com)
  • Here, a tissue-specific hybrid bioink is described, composed of a natural polymer, alginate, reinforced with extracellular matrix derived from decellularized tissue (rECM). (lu.se)
  • 2) to investigate the role of HO-1 and its products, CO and bilirubin, in protecting renal tissues during hypothermic storage and subsequent reperfusion. (ucl.ac.uk)
  • 3) to search for novel "pharmacological preconditioning agents" that are capable of selectively activating the HO-1 gene in renal tissues. (ucl.ac.uk)
  • The results show that, following induction of HO-1 in renal tissue, the enzymatic activity was maintained during hypothermia, and some beneficial effects on renal function could be observed after storage and reperfusion. (ucl.ac.uk)
  • To organise this urgently needed transplant, kinderherzen approached the non-profit DGFG, which is the largest tissue donation network in Germany. (gewebenetzwerk.de)
  • Without tissue donation, we would not be able to perform procedures such as the Ross operation, which is a great source of hope for young patients in particular - neither in Germany nor in Romania. (gewebenetzwerk.de)
  • The transplanted heart valve comes from post-mortem tissue donation . (gewebenetzwerk.de)
  • and recall of stored tissues from donors found after donation to have been infected. (cdc.gov)
  • Final Round of 2022 CSP Functional Genomics Awardees Meet the final six researchers whose proposals were selected for the 2022 Community Science Program Functional Genomics call. (doe.gov)
  • Tests also showed scarring and stiffness of the lung tissue. (cdc.gov)
  • These findings may shed light on the mechanism underlying tissue-specific phenotypes in diseases associated with minor spliceosome inactivation. (biomedcentral.com)
  • In 1985, when tests for HIV antibody became available, screening prospective donors of blood, organs, and other tissues also began (2,3). (cdc.gov)
  • We identified a unique peptide from angiopoitin-1 that enables collective cell migration and decreases inflammation in 6 different tissue models. (utoronto.ca)
  • Interstitial lung disease involves inflammation of the lung's air sacs and airways and scarring of tissue that causes the lungs to become stiff, small, and less effective at transferring oxygen into the blood and carbon dioxide out from the blood. (cdc.gov)
  • We conducted genetic and functional analyses of persons ( 3 ), reminiscent of a disease course more common- isolates from a patient with group B streptococcal (GBS) ly associated with group A streptococci or Staphylococcus necrotizing fasciitis and toxic shock syndrome. (cdc.gov)
  • Focal dermal hypoplasia (FDH) is an uncommon genetic disorder affecting tissues of ectodermal and mesodermal origin. (medscape.com)
  • Among these techniques, we utilize displacement- and strain-sensitive MRI imaging techniques and image processing to measure tissue deformations under applied loading. (purdue.edu)
  • Tissue oximetry studies using magnetic resonance imaging are increasingly contributing to advances in the imaging and treatment of cancer. (spie.org)
  • Statement of Significance: With thousands of patients dying each year waiting for an organ transplant, bioprinted tissues and organs show the potential to eliminate this ever-increasing organ shortage crisis. (psu.edu)
  • The common ground, however, may come if significant treatment or cures are found with fetal tissue research by scientists anywhere in the world. (religionnews.com)
  • Thanks to the introduction of radiomics, 3d reconstruction can be able to analyse tissues and recognise true hypertrophy from non-functioning tissue in patients treated with major hepatectomies with hepatic mo. (biomedcentral.com)
  • Using cutting edge detectors or even varying x-ray energy levels, spectral, or multi-energy, CT provides information-rich images that scale with the unique patterns of x-ray attenuation of different elements within a tissue. (purdue.edu)
  • Co-first authors of the study Kimberly Homan, a Wyss Research Associate, and David Kolesky, a Wyss Postdoctoral Fellow, stress that the most exciting aspect of the work is that - far beyond mimicking the form of the kidney's proximal tubule -it is a credible in vitro model that functions like living kidney tissue, representing a significant advance from traditional 2D cell culture. (harvard.edu)
  • The field of tissue engineering is constantly evolving as it aims to develop bioengineered and functional tissues and organs for repair or replacement. (mdpi.com)
  • Beyond simply images of tissue morphology, MRI can therefore be used to probe the mechanical behavior, material properties, and the biochemical content of tissues and other biomaterials. (purdue.edu)
  • Conventional computed tomography (CT) and microCT provides high-resolution 'grayscale' images, especially when paired with contrast agents designed to target tissues of interest or biochemical content by capturing the degree to which a tissue blocks, or attenuates, x-rays. (purdue.edu)
  • Concordantly in this same region, the heart's local microstructural tissue helicity is also selectively increased in exercised mice. (researchgate.net)
  • To generate the non-functional pairs (negative pair), we use the Gene Ontology annotations tagged with "NOT" qualifier. (figshare.com)