Tissue from stromal tissue. Medical search. Frequent questions

Gastrointestinal stromal tumors (GISTs) account for less than 1% of GI tumors, but they are the most common mesenchymal neoplasms of the GI tract. (medscape.com)
These tumors can occur in different parts of the body, including the gastrointestinal tract, reproductive organs, and soft tissues. (gokhanakbulut.com)
The diagnosis of stromal tumors, including GIST, often involves imaging studies such as CT scans or MRI, followed by a biopsy to examine the tissue under a microscope. (gokhanakbulut.com)
Treatment options for stromal tumors depend on various factors, including the tumor size, location, and whether it is benign or malignant. (gokhanakbulut.com)
It's important to consult with a medical professional for an accurate diagnosis, proper management, and individualized treatment plan if you have concerns about stromal tumors or any health condition. (gokhanakbulut.com)
The incidence of stromal tumors, specifically gastrointestinal stromal tumors (GIST), can vary depending on the population and region being studied. (gokhanakbulut.com)
These extragastrointestinal stromal tumors (EGISTs) have been reported in various locations, including the mesentery, omentum, retroperitoneum, and other soft tissues. (gokhanakbulut.com)
It's important to remember that the incidence rates mentioned above are general estimates, and the actual incidence of stromal tumors can vary in different populations and geographical areas. (gokhanakbulut.com)
For more specific and accurate information regarding the incidence of stromal tumors in a particular region, it is advisable to refer to medical literature or consult with healthcare professionals or oncologists familiar with local statistics and data. (gokhanakbulut.com)
Laboratory tests and X-rays are commonly used diagnostic tools to aid in the evaluation of various medical conditions, including stromal tumors or any other health issue. (gokhanakbulut.com)
However, it's important to note that these tests alone may not be sufficient for diagnosing stromal tumors definitively. (gokhanakbulut.com)
How are gastrointestinal stromal tumors diagnosed? (arupconsult.com)
Suspected gastrointestinal (GI) stromal tumors (GISTs) usually present initially with GI bleeding (the most common manifestation), abdominal pain, and obstructive symptoms. (arupconsult.com)
What is the role of mutational analysis in determining therapy for gastrointestinal stromal tumors? (arupconsult.com)
KIT / PDGFRA mutational assessment is important for decision-making and treatment purposes, given that gastrointestinal (GI) stromal tumors (GISTs) have a variety of subtypes with different predictive and prognostic relevance. (arupconsult.com)
These tumors start in the tissues that connect and support the body. (cancercenter.com)
As little is known about epithelial-stromal interactions in vivo, it is necessary to visualize the stroma surrounding normal epithelium and mammary tumors in intact tissues to better understand how matrix organization, density, and composition affect tumor formation and progression. (biomedcentral.com)
Epithelial-stromal interactions in normal mammary glands, mammary tumors, and tumor explants in three-dimensional culture were studied with histology, electron microscopy, and nonlinear optical imaging methodologies. (biomedcentral.com)
The presentation of these tumor-associated collagen signatures allowed us to identify pre-palpable tumors and see cells at the tumor-stromal boundary invading into the stroma along radially aligned collagen fibers. (biomedcentral.com)
As such, TACS should provide indications that a tumor is, or could become, invasive, and may serve as part of a strategy to help identify and characterize breast tumors in animal and human tissues. (biomedcentral.com)
One important step to elucidating these signaling interactions is to determine the organization of the collagenous stroma surrounding both normal mammary glands and tumors within intact tissue so as to better understand the cell-matrix interaction and how matrix organization, density, and composition affect tumor formation and progression. (biomedcentral.com)
Gastrointestinal stromal tumors (GISTs) are a subset of GI mesenchymal tumors of varying differentiation. (medscape.com)
Grossly, gastrointestinal stromal tumors are well-demarcated spherical masses that appear to arise from the muscularis propria layer of the GI wall. (medscape.com)
With the development of tumor molecular heterogeneity theory(12), there are still some patients with GIST who are sensitive to radiotherapy, especially for the patients with advanced stage(13-16).In addition, with the development of imaging technology and modern tissue and organ radiation technology, it has become a reality to concentrate high-dose radiation locally in abdominal cavity tumors(12), which challenges RT's insensitivity to GISTs. (researchsquare.com)
Epithelial tumors form in the tissue around your ovaries. (webmd.com)
There's some evidence that Black women are a little more likely to have germ-cell and stromal tumors, compared to other groups. (webmd.com)
The National Comprehensive Cancer Network (NCCN) Soft Tissue Sarcoma Panel specifically identifies Li-Fraumeni syndrome and familial adenomatous polyposis (FAP) as genetic cancer syndromes with a predisposition for the development of soft tissue sarcoma, along with Carney-Stratakis syndrome, which is associated with gastrointestinal stromal tumors (GISTs). (medscape.com)
In 2013 the World Health Organization released an update of its 2002 classification system for tumors of the soft tissue and bone. (medscape.com)
Gastrointestinal stromal tumors (GIST) are staged separately from other sarcomas, with tumors graded as low or high. (medscape.com)
NEW YORK (Reuters Health) - Young adults with gastrointestinal stromal tumors (GISTs) appear to fare best after undergoing operative treatment, according to a retrospective study. (medscape.com)
There are three types of ovarian cancers: epithelial ovarian carcinomas, germ cell tumors, and stromal cell tumors. (medlineplus.gov)

Shown here is a gastric gastrointestinal stromal tumor (GIST). (medscape.com)
The most well-known and common type of stromal tumor is called gastrointestinal stromal tumor (GIST). (gokhanakbulut.com)
A gastrointestinal stromal tumor (GIST) is a type of cancer that develops in the gastrointestinal (GI) tract. (cancercenter.com)
Non-gastrointestinal stromal tumor (GIST) smooth tissue sarcomas (STSs) certainly are a heterogeneous band of neoplasms whose classification and administration is constantly on the evolve with better knowledge of their biologic behavior. (ap26113.com)
The initial as well as the most effective example was the breakthrough of package mutations in gastrointestinal stromal tumor (GIST), and following advancement of the selective tyrosine kinase inhibitor imatinib, which revolutionized the treating GIST (3). (ap26113.com)
Small-bowel gastrointestinal stromal tumor with a diffusely thickened bowel wall. (medscape.com)
Gastric gastrointestinal stromal tumor (GIST) en face. (medscape.com)

Adipose tissue (AT) represents a commonly used source of mesenchymal stem/stromal cells (MSCs) whose proregenerative potential has been widely investigated in multiple clinical trials worldwide. (mdpi.com)
Mesenchymal stromal cells (MSCs) show great promise for a wide range of applications including treating graft-vs-host disease, rheumatoid arthritis and cardiovascular diseases, as well as in tissue-engineering. (nanomelbourne.com)
This can be attributed to the direct differentiation of MSCs into the cells that form tissues such as bone or cartilage, or the activity of the factors that MSCs secrete which can have powerful regenerative properties. (nanomelbourne.com)
Bioengineered systems therefore gave a huge role to play in building essential understanding of how the cells respond to different physical cues, as well as in developing new technologies that harness these effects to promote tissue repair. (nanomelbourne.com)
Stromal tumor refers to a type of tumor that arises from the connective tissue cells, known as stromal cells, which provide structural support to various organs and tissues in the body. (gokhanakbulut.com)
Scholars@Duke publication: Single-cell RNA-seq of out-of-thaw mesenchymal stromal cells shows tissue-of-origin differences and inter-donor cell-cycle variations. (duke.edu)
BACKGROUND: Human Mesenchymal stromal cells (hMSCs) from various tissue sources are widely investigated in clinical trials. (duke.edu)
These findings contribute to our understanding of tissue origin-based differences in out-of-thaw therapeutic hMSC products and assist in the identification of cells with immune-regulatory or survival potential from a heterogeneous MSC population. (duke.edu)
Culture expansion of adipose derived stromal cells. (nih.gov)
Adipose derived stromal cells (ASCs) are a rich and convenient source of cells for clinical regenerative therapeutic approaches. (nih.gov)
iXCells Biotechnologies provides SVF from human subcutaneous white fat tissue by enzymatic isolation and cryopreserved at P0, with ≥ 1.0 million cells/vial (Normal) or 0.5 million cells/vial (Diseased). (ixcellsbiotech.com)
Stromal vascular fraction (SVF), containing large amount of stem cells and other regenerative cells, can be easily obtained from loose connective tissue that is associated with adipose tissue. (naturopathicstandards.org)
Stromal cells originate from multipotent mesenchymal stem cells. (wikipedia.org)
In the medulla are hematopoietic cells (which contribute to the formation of the blood) and stromal cells. (wikipedia.org)
The lymph tissue in the lymph nodes consists of immune cells (95%), for example lymphocytes, and stromal cells (1% to 5%) The genesis of lymph nodes begins within the blood and the lymphatic system. (wikipedia.org)
Interactions between stromal and hematopoietic cells are important for the development of lymph nodes. (wikipedia.org)
Crosstalk LEC, lymphoid tissue inducer cells and mesenchymal stromal organizer cells initiate the formation of lymph nodes. (wikipedia.org)
The primary role of lymph node stromal cells is structural. (wikipedia.org)
The molecular signaling systems (chemokines) that distribute lymphocytes to appropriate localities within the lymph node (T and B cell segregation) are also created by lymph node stromal cells. (wikipedia.org)
Lymph node stromal cells express peripheral tissue-restricted antigens (PTAs) on their surface. (wikipedia.org)
The Transcription factor Aire (autoimmune regulator) that controls the expression of PTAs on mTEC cells in the thymus is only expressed at low levels by uncharacterized double negative stromal cells. (wikipedia.org)
Most lymph node stromal cells preferentially express DF1, an Aire-like transcription modulator. (wikipedia.org)
Organoids are derived from three major cell types: tissue-restricted adult stem cells, pluripotent stem cells and, in the case of tumour organoids, tumour cells (reviewed in 3,4 ). (researchsquare.com)
In this study, we report the 3D reconstitution of normal bladder and patient-specific bladder tumour "assembloids" - organoids derived from tissue stem/tumour cells reconstituted with other components of the tissue stroma/microenvironment such as stromal fibroblasts, endothelial cells, and muscle cells. (researchsquare.com)
Previously, we showed that exosomes derived from human adipose tissue-derived mesenchymal stem cells (ASC-exosomes) attenuate AD-like symptoms by reducing multiple inflammatory cytokine levels. (mdpi.com)
However, transplanting other than hematopoietic stem and progenitor cells is still limited to a few applications, and it mainly applies to mesenchymal stromal cells (MSCs) isolated from bone marrow. (hindawi.com)
Recently, MSCs isolated from bone marrow (bmMSCs) were shown to be a blend of distinct cells and MSCs isolated from different tissues show besides some common features also some significant differences. (hindawi.com)
Nowadays, experts agree that MSCs may generate upon appropriate stimulation quite different mature cells including osteoblasts, chondrocytes, tenocytes, adipocytes, smooth muscle cells, and stromal cells of the bone marrow [ 9 ]. (hindawi.com)
Mesenchchymal stromal cells (MSCs) have been extensively used as second-line treatment for acute GvHD. (alchimiasrl.com)
Expanded cells expressed MSC markers and were able to differentiate into mesodermal tissues and to exert immunomodulatory activity on activated lymphocytes. (alchimiasrl.com)
In our center we have both the availability of tissues and cells thanks to donors and to the connection to the hospital and the knowledge of aseptic tissue manipulation, thus filling the gap from bench to bedside. (alchimiasrl.com)
The certified line completely dedicated to the processing of human tissues and cells intended for transplanation. (alchimiasrl.com)
Adaptive redox response of mesenchymal stromal cells to stimulation with lipopolysaccharide inflammagen: mechanisms of remodeling of tissue barriers in sepsis. (biomedfrontiers.org)
These microenvironments are classically defined as distinct cortex and medulla regions that each contain specialized subsets of stromal cells. (frontiersin.org)
Significantly, there are additional non-epithelial stromal cells (NES) that exist alongside TEC within thymic microenvironments, including multiple subsets of mesenchymal and endothelial cells. (frontiersin.org)
While adult lymphoid progenitor cells are produced by the bone marrow, their lineage commitment and development into mature T-cells is dependent on their migration into the thymus, where essential interactions with heterogeneous thymic stromal cells take place ( 1 ). (frontiersin.org)
Arguably, the most recognized and well-studied stromal populations in thymus biology are thymic epithelial cells (TEC) within the cortical and medullary areas, which are defined by their anatomical separation and function. (frontiersin.org)
We show that depletion of CAVIN1 in prostate stromal cells markedly reduces their lipid droplet accumulation and increases inflammation. (aacrjournals.org)
Stromal cells lacking CAVIN1 enhance prostate cancer cell migration and invasion. (aacrjournals.org)
Our data support the concept that stromal cells contribute to prostate cancer aggressiveness by modulating lipid content and inflammation in the tumor microenvironment. (aacrjournals.org)
Bone marrow stromal cells (BMSC) are multipotent stem cells and are considered good candidates for cell restoration in injured brain tissue. (sld.cu)
Bone marrow stromal cells (BMSC) are adult stem cells with characteristics that make them an attractive candidate in cellular therapy for neurological diseases (1). (sld.cu)
These effects were partially mediated through enhanced TGF-β signaling, which contributes to tissue fibrosis and epithelial-mesenchymal transition (EMT) of tumor cells. (jci.org)
Our results highlight the crucial role of ETP as an obesity-associated factor that promotes tumor growth in the context of adipocyte interactions with tumor and stromal cells. (jci.org)
Ovaries are mostly made of three kinds of cells: epithelial, germ, and stromal. (webmd.com)
Mesenchymal stromal cells (MSCs) are widely spread in adult organisms. (weizmann.ac.il)
Primary cultured cells of endometrial tissues were analysed using RT-PCR and western blotting (WB) to determine expression of H19 and ACTA2. (iasp-pain.org)
De- cidual cells promote hemostasis through enhanced expression of tissue factor (TF), the primary initiator of hemostasis via thrombin generation, and plasminogen activator inhibitor-1, which inactivates tissue type plasminogen activator, the primary fibrinolytic agent. (scirp.org)
2009) Progestin and thrombin regulate tissue factor expression in human term decidual cells. (scirp.org)
Immunohistochemistry using a monoclonal antibody against Cx43 confirmed the distribution of gap junctions between stromal fibroblastic cells, which was compatible with the ultrastructural findings. (nih.gov)
The main constituent of the human thyroid stromal tissue was a CD34 positive reticular network involving fibroblasts, mononuclear cells and nerve terminals. (nih.gov)
Mesenchymal stem/stromal cells (MSCs) regulate wound repair processes in the lung, and may contribute to either proresolution or -fibrotic lung responses. (cdc.gov)
The migrated cells reduce the corneal stromal edema and vision improves. (msdmanuals.com)
Given this, the ALINE MANICA2 cryopreservation of adipose tissue-derived mesenchymal stem cells (ADMSCs) could be a JULIANA CRISTINA SCHMIDT2 way to collect them in one surgical procedure and after performing fractional fat grafting. (bvsalud.org)
Methods: Pulp tissue was collected from permanent third molars and digested and then the cells were seeded onto plates containing HDMEM medium. (bvsalud.org)
Conclusions: The cells isolated from dental pulp exhibited characteristics compatible with those expected for mesenchymal stem cells (MSCs) and are good candidates for cell therapy applications and tissue bioengineering. (bvsalud.org)
Stem cells are cells with a low degree of differentiation that have the capacity to reproduce and can generate differentiated cells of several different types of tissues 1 . (bvsalud.org)
Pulp stem cells (PSCs) are able to form ectopic dentin in vitro and in vivo and also to generate a dentine-pulp complex composed of a mineralized matrix, with dentinal tubules that are aligned and filled with odontoblastic prolongations, containing vascularized pulp tissue, in a similar arrangement to that observed in natural dental structures 3,6 . (bvsalud.org)

Review the newer molecular genetic testing techniques used for the diagnosis of GIST and other soft tissue sarcomas (STS). (nccn.org)

GISTs belong to a different family of cancers called soft tissue sarcomas . (cancercenter.com)

We then apply this knowledge to improve the design of systems for MSC differentiation and tissue formation, for example, by delivering microRNA:nanoparticle complexes to modulate mechanosensitive signalling pathways in MSCs encapsulated in hydrogels and promote osteogenesis for bone tissue engineering. (nanomelbourne.com)
These MSCs are often administered to patients immediately after thawing the cryopreserved product (out-of-thaw), yet little is known about the single-cell transcriptomic landscape and tissue-specific differences of out-of-thaw human MSCs. (duke.edu)
But research progressed and different trials explore the clinical potential of human MSCs isolated from bone marrow but also from other tissues including adipose tissue. (hindawi.com)
Overview of studies published regarding MSCs using the term "stem cell" or "stromal cell" in the last 20 years accessed by a web search in July 2015 (Google Scholar). (hindawi.com)
Furthermore, MSCs may assist the recovery of injury sites and are thought to contribute to tissue maintenance. (weizmann.ac.il)

Adipose tissue-derived stromal vascular fraction in regenerative medicine: a brief review on biology and translation. (ixcellsbiotech.com)

We previously demonstrated the critical involvement of SRC-2 in murine embryo implantation as well as in human endometrial stromal cell (HESC) decidualization, a cellular transformation process required for trophoblast invasion and ultimately placentation. (frontiersin.org)
Alterations in the H19/miR-216a-5p/ACTA2 pathway may mediate the regulation of eutopic endometrial stromal cell (euESC) invasion and migration and may represent a potential mechanism underlying fibrous tissue formation or fibrosis in women with endometriosis. (iasp-pain.org)

Experiments are conducted on a breast tissue microarray having benign tissues (BT), malignant invasive lobular carcinoma (ILC), and benign stroma adjacent to the malignant tissues (called the benign adjacent tissue, or BAT). (illinois.edu)
Our work provides a resource characterizing the role of tissue stroma in regulating mucosal tissue homeostasis and disease pathogenesis . (bvsalud.org)
Tumor stroma promotes tumor proliferation, invasion, and metastasis, but how stromal lipids influence these processes remain to be defined. (aacrjournals.org)
in a corneal transplant technique known as deep anterior lamellar keratoplasty (DALK) the donated corneal tissue replaces the corneal stroma and epithelium only. (msdmanuals.com)
Only the corneal endothelium needs to be transplanted in diseases where the corneal stroma is clear, has a smooth stromal surface with a regular curvature, and only the corneal endothelium is not functioning well (eg, Fuchs dystrophy, bullous keratopathy resulting from cataract surgery). (msdmanuals.com)

These molecular findings are supported at the cellular level by the inability of HESCs to morphologically transform from a stromal fibroblastoid cell to an epithelioid decidual cell when endogenous SRC-3 levels are markedly reduced. (frontiersin.org)
It is anticipated that a concerted multidiscipline approach is required to facilitate the reality and great potential benefits of cell-based tissue engineering applications. (sahmri.org.au)
METHODS: 13 hMSC samples derived from 10 'healthy' donors were used to assess donor variability and tissue-of-origin differences in single-cell gene expression profiles. (duke.edu)
However, differences between donors, tissue-of-origin, and cell cycle are evident in both TNF suppression and cytokine secretion. (duke.edu)
In this study, cultivation of ASCs from stromal vascular fraction (SVF) over two passages in the automated and functionally closed Quantum Cell Expansion System (Quantum system) is compared with traditional manual cultivation. (nih.gov)
Please see the Nature Portfolio Collection on Stromal-Immune Cell Interactions. (nature.com)
You will find recent research articles and reviews that discuss the players and factors involved in stromal-immune cell interactions in both health and disease. (nature.com)
Feline adult adipose tissue-derived multipotent stromal cell isolation" by C. Fargason, N. Zhang et al. (lsu.edu)
Human oral mucosa cell atlas reveals a stromal-neutrophil axis regulating tissue immunity. (bvsalud.org)
To aid in understanding tissue -specific pathophysiology, we compile a single- cell transcriptome atlas of human oral mucosa in healthy individuals and patients with periodontitis . (bvsalud.org)
We uncover the complex cellular landscape of oral mucosal tissues and identify epithelial and stromal cell populations with inflammatory signatures that promote antimicrobial defenses and neutrophil recruitment . (bvsalud.org)
Our findings link exaggerated stromal cell responsiveness with enhanced neutrophil and leukocyte infiltration in periodontitis . (bvsalud.org)
Here, we create multi-layered normal bladder assembloids and tumour assembloids by reconstituting tissue stem cell/tumour cell-derived organoids with multiple stromal components to represent an organized tissue architecture and functionality of adult bladder, and to mimic in vivo pathophysiological features of patient-derived urothelial carcinoma, respectively. (researchsquare.com)
Harvest tissue source does not alter the protective power of stromal cell therapy following intestinal ischemia and reperfusion injury. (logosbio.com)
Advancements in cellular and molecular biology led to the development of the so-called Advanced Therapy Medicinal Products (ATMP) namely gene therapy, somatic cell therapy and tissue engineering products. (alchimiasrl.com)
While many studies have demonstrated the importance of cTEC and mTEC during T-cell development, thymic stromal microenvironments also contain heterogenous non-epithelial stromal (NES) populations in a similar manner to that seen in peripheral lymphoid tissues. (frontiersin.org)
The estrogen-regulated lncRNA H19/miR-216a-5p axis alters stromal cell invasion and migration via ACTA2 in endometriosis. (iasp-pain.org)
Effects of agricultur al organic dusts on human lung-resident mesenchymal stem (stromal) cell function. (cdc.gov)
These findings warrant future investigations to assess how organic dusts affect lung-resident mesenchymal stem/stromal cell function and impact airway inflammation, injury, and repair during agricultur al aerosol exposures. (cdc.gov)
However, most GEP studies have typically been performed on whole tissue samples, containing varying degrees of tumor cell content, which results in uncertainties in data analysis. (lu.se)
Stem cell-based therapies offer a potential therapeutic approach to repair, restore, or regenerate injured brain tissue. (lu.se)

Interfollicular stromal fibroblasts also stained with CD34. (nih.gov)

abstract = "Although preliminary results have been achieved on many different fronts in applying BMSSC technology to tissue engineering, a tremendous amount of work still confronts researchers in this area. (sahmri.org.au)

Stromal vascular fraction was isolated from abdominal fat, suspended in α-MEM supplemented with 10% Fetal Bovine Serum and seeded into either T75 flasks or a Quantum system that had been coated with cryoprecipitate. (nih.gov)
Stromal vascular progenitors in adult human adipose tissue. (ixcellsbiotech.com)
Stromal Vascular Fraction and its Role in the Management of Alopecia: A Review. (ixcellsbiotech.com)

We present the results of polarimetric analysis of collagen on varying pathologies of breast tissues using second-harmonic patterned polarization-analyzed reflection confocal (SPPARC) microscopy. (illinois.edu)
We observe that stromal collagen readings in ILC show lower depolarization, lower diattenuation and higher linear degree-of-polarization values than stromal collagen in BAT. (illinois.edu)
Moreover, collagen-dense breast tissue increases the risk of breast carcinoma, although the relationship between collagen density and tumorigenesis is not well understood. (biomedcentral.com)
Imaging of the tumor-stromal interface in live tumor tissue ex vivo was performed with multiphoton laser-scanning microscopy (MPLSM) to generate multiphoton excitation (MPE) of endogenous fluorophores and second harmonic generation (SHG) to image stromal collagen. (biomedcentral.com)
Collagen VI (COL6) is highly expressed in adipose tissue, upregulated in the obese state, and enriched in breast cancer lesions and is a stimulator of mammary tumor growth. (jci.org)

Stromal-epithelial interactions are of particular significance in breast tissue as misregulation of these interactions can promote tumorigenesis and invasion. (biomedcentral.com)

hMSCs derived and expanded from the bone marrow (BM) or cord tissue (CT) underwent controlled-rate freezing for 24 h. (duke.edu)

Athelia (ie, absence of nipples) and amastia (ie, absence of breast tissue) may occur bilaterally or unilaterally. (medscape.com)
Accessory or ectopic breast tissue responds to hormonal stimulation and may cause discomfort during menstrual cycles. (medscape.com)
Mastitis neonatorum or infections of the breast tissue may also occur during the newborn period. (medscape.com)
In some cases however breast cancer could also develop in the stromal tissues. (home-remedies-for-you.com)
The breast comprises of a lot of fatty and fibrous tissue, which is referred to as the stromal tissues. (home-remedies-for-you.com)

Current organoid models are limited by their inability to mimic mature organ architecture and associated tissue microenvironments 1,2 . (researchsquare.com)

Our assembloid model will facilitate development of an innovative model system for studying tissue regeneration and tumourigenesis at molecular and cellular levels, and also provide a unique experimental tool for establishing novel personalized therapeutic options, such as new drug screening strategies that are customized for different stages and types of cancer in individual patients. (researchsquare.com)
Tissue bioengineering has the capacity to accelerate regeneration and repair of damaged tissues using patients' natural curative potential and it is facilitated by several types of biomaterials 2 . (bvsalud.org)

Congenital stromal corneal dystrophy is an inherited eye disorder. (medlineplus.gov)
Congenital stromal corneal dystrophy is caused by mutations in the DCN gene. (medlineplus.gov)

In the cortex, lymphoid tissue is organized into nodules. (wikipedia.org)

Soon after birth, the nipples are raised from the shallow mammary pits by proliferation of the surrounding connective tissue. (medscape.com)

Some blood-vessel sarcomas can affect the lymphatic system (which carries fluid from soft tissue to lymph nodes). (sarctrials.org)

Bredrup C, Knappskog PM, Majewski J, Rodahl E, Boman H. Congenital stromal dystrophy of the cornea caused by a mutation in the decorin gene. (medlineplus.gov)
Van Ginderdeuren R, De Vos R, Casteels I, Foets B. Report of a new family with dominant congenital heredity stromal dystrophy of the cornea. (medlineplus.gov)

Afferent lymphatic vessels bring lymph fluid from the peripheral tissues to the lymph nodes. (wikipedia.org)

Conversely, brown adipose tissue (BAT) and browning of WAT represent potential therapeutic approaches, since dysfunctional white adipocyte-induced lipid overspill can be halted by BAT/browning-mediated oxidative anti-lipotoxic effects. (springer.com)

This study showed that stromal CAVIN1 suppresses prostate cancer metastasis by modulating tumor microenvironment, lipid content, and inflammatory response. (aacrjournals.org)
Stromal function in the evolving tumor microenvironment: a role in immune modulation? (ehaweb.org)

The 'adipose tissue expandability model' identifies the limited capacity and dysfunctionality of WAT, preventing its expansion and accommodation of surplus of energy, as key determinants for the onset and progression of obesity-associated metabolopathologies as a result of ectopic deposition of toxic lipid species in metabolic organs (i.e. muscle or liver [also known as lipotoxic insult]) [ 7 ]. (springer.com)
These organoids are widely used for modelling key characteristics of organs and tissues to better understand various aspects of human disease such as cancer. (researchsquare.com)
The peritoneum is a tissue that lines the abdomen and most of the organs in the abdomen. (cancer.net)
A fold of this tissue called the omentum covers and connects the organs in the abdomen. (cancer.net)
All ovarian cancers involve one or both ovaries, or in the nearby tissue that covers organs in the abdomen (belly area). (medlineplus.gov)

In this study, we aimed to determine the expression of H19 and ACTA2 in endometrial tissues of women with endometriosis. (iasp-pain.org)

The diagnosis and treatment of soft tissue sarcomas (STS) has been updated within recent years. (nccn.org)
Soft-tissue sarcomas are more common than bone sarcomas. (sarctrials.org)
The 50 different types of soft-tissue sarcomas differ in terms of their tissue of origin, clinical behavior, age of occurrence, aggressiveness, the way they spread, genetic alterations, and their sensitivity to certain therapies. (sarctrials.org)
Some sarcomas that arise in soft tissue mimic those that typically arise in cartilage or bone. (sarctrials.org)
[ 5 ] and the National Cancer Institute system are most commonly used for grading soft tissue sarcomas. (medscape.com)
The National Comprehensive Cancer Network (NCCN) workup for soft tissue sarcomas of the extremities, superficial trunk, or head and neck includes evaluation and management prior to initiation of therapy by a multidisciplinary team with expertise and experience in sarcoma. (medscape.com)

These accessory tissues have been reported to undergo malignant transformation and should be removed. (medscape.com)

We show here that, like SRC-2, SRC-3 is expressed in the epithelial and stromal cellular compartments of the human endometrium during the proliferative and secretory phase of the menstrual cycle as well as in cultured HESCs. (frontiersin.org)
This is a site of rich exposure to antigens and commensals, and a tissue susceptible to one of the most prevalent human inflammatory diseases , periodontitis . (bvsalud.org)
In order to characterize more fully and assess its possible functions, 15 samples of surgical and autopsy human thyroid tissue were studied by classical histology, immunohistochemistry, transmission electron microscopy, electron microscopic immunohistochemistry, and scanning electron microscopy. (nih.gov)
To address this gap in knowledge, we isolated human lung-resident MSC from lung tissue. (cdc.gov)

Here, we summarise the mechanisms contributing to adipose tissue (AT) plasticity and function including characteristics and cellular complexity of the various adipose depots and we discuss recent insights into AT origins, identification of adipose precursors, pathophysiological regulation of adipogenesis and its relation to WAT/BAT expandability in obesity and its associated comorbidities. (springer.com)

Many studies have demonstrated tissue bioengineering's potential and its applications for dentistry and regenerative medicine 3-5 . (bvsalud.org)

Le pourcentage de CD44 dans les lymphocytes T périphériques était significativement plus élevé chez les patients que chez les témoins, comme détecté par la cytométrie en flux. (who.int)

I want to calculate immune scores and stromal scores by employing the ESTIMATE algorithm, then analyze the relationship of immune/stromal scores with subtype classification and cytogenetic risk by one-way analysis of variance, but I don't know how to do this! (biostars.org)

They form in the tissues that support the ovaries. (medlineplus.gov)

The lymph from the peripheral tissues contains soluble antigens and arrives at the lymph node via afferent lymphatic vessels. (wikipedia.org)
White adipose tissue (WAT) plays a key homeostatic role, not only by ensuring efficient energy storage but also by its quick mobilisation (lipids) to ensure peripheral demands. (springer.com)

Anatomy16

Organisms1

Diseases8

Chemicals and Drugs11

Analytical, Diagnostic and Therapeutic Techniques and Equipment8

Phenomena and Processes8

Disciplines and Occupations1

Tumors31

Gastrointestinal strom7

Cells58

GIST1

GISTs1

MSCs5

Adipose tissue-derived stromal1

Endometrial stromal2

Stroma5

Cell21

Fibroblasts1

Abstract1

Vascular3

Collagen5

Interactions1

Bone marrow1

Breast5

Microenvironments1

Regeneration2

Corneal2

Lymphoid1

Connective tissue1

Lymphatic system1

Dystrophy2

Lymph nodes1

Therapeutic1

Tumor microenvironment2

Organs5

Expression1

Sarcomas6

Malignant1

Human4

Cellular1

Regenerative1

Lymphocytes1

Immune1

Ovaries1

Peripheral2