Tissue expansion. Medical search. Frequent questions

The circadian clock component NR1D1 (REVERBα) is considered a dominant regulator of lipid metabolism, with global Nr1d1 deletion driving dysregulation of white adipose tissue (WAT) lipogenesis and obesity. (elifesciences.org)
Adipose tissue (AT) represents a commonly used source of mesenchymal stem/stromal cells (MSCs) whose proregenerative potential has been widely investigated in multiple clinical trials worldwide. (mdpi.com)
In collaboration with our academic and industrial partners, studies are performed to investigate the links and the cross-talk between adipose tissue and the brain, also to understand the links between fat mass expansion and oxidative stress and inflammation in nerve cells, as well as investigating the potential preventive and protective effects of plant-based medicines. (buckingham.ac.uk)
The accumulation of sub-dermal adipose tissue and, consequently, increased pro-inflammatory cytokine release could affect the dermal fibroblast physiology. (buckingham.ac.uk)
Adipocyte glucocorticoid receptor activation with high glucocorticoid doses impairs healthy adipose tissue expansion by repressing angiogenesis. (c3m-nice.fr)
We recently reported that adipocyte glucocorticoid receptor (GR)-deficient (AdipoGR-KO) mice under corticosterone (CORT) treatment exhibited a massive adipose tissue (AT) expansion associated with a paradoxical improvement of metabolic health compared to control mice. (c3m-nice.fr)
Obesity is defined as an excess accumulation of white adipose tissue associated with a low grade inflammation which is one contributor to obesity complications such as diabetes. (springer.com)
Recently, we and others have demonstrated fibrotic depots in white adipose tissue of obese subjects. (springer.com)
In the first one, local adipose tissue hypoxia could induce fibrosis accumulation which in turn through adipocyte dysfunctions might provoke adipose tissue inflammation. (springer.com)
In the second one, fibrosis could be a result of local adipose tissue inflammation induced by tissue expansion. (springer.com)
Obesity is defined as an expansion of white adipose (WAT) tissue that is associated with low grade inflammation which possibly contributes to the development of health complications such as diabetes, liver pathologies, dyslipidemia, cardiovascular diseases as well as some cancers [ 2 - 4 ]. (springer.com)
However many more pro and anti-inflammatory mediators produced by the adipose tissue have been described since then. (springer.com)
Donor age negatively impacts adipose tissue-derived mesenchymal stem cell expansion and differentiation. (bvsalud.org)

multiple changes occur in the tissues overlying the expanders during the process of expansion. (medscape.com)

Staged scalp soft tissue expansion before delayed allograft cranioplasty: a technical report. (prolekare.cz)
Facial soft-tissue changes after rapid maxillary expansion analyzed with 3-dimensional stereophotogrammetry: A randomized, controlled clinical trial. (3dmd.com)
To evaluate three-dimensional (3D) soft tissue facial changes following rapid maxillary expansion (RME) and to compare these changes with an untreated control group. (3dmd.com)
Skeletal and soft tissue changes were evaluated using posteroanterior cephalograms and 3-D facial images from 3dMD. (3dmd.com)
The primary outcome of this study was to assess the soft tissue changes. (3dmd.com)
The secondary outcomes were evaluation hard tissue and soft tissue relations. (3dmd.com)
Pogonion soft tissue point (P=0.022) was located more posteriorly in the expansion group compared with the control group. (3dmd.com)
Soft tissue changes between groups were similar, except for the alar base, which became wider in the treatment group. (3dmd.com)
Weak correlations were found between the skeletal and soft tissue changes. (3dmd.com)
Intraoperative tissue expansion is advocated as a technique to facilitate closure of soft-tissue wounds with less tension than if they were closed primarily without expansion or, presumably, simple undermining. (northwestern.edu)
A procedure whereby the body is stimulated to generate extra soft tissue by the application of stretching forces that stimulate new growth of tissue which, over a period of time, results in a 2-dimensional expansion of the tissue. (bvsalud.org)
The soft tissue within this region is commonly divided into 5 layers: skin, subcutaneous tissue, aponeurosis (galea), loose areolar tissue, and pericranium. (medscape.com)
Pre-operative planning includes soft tissue evaluation, and the type of presenting maxillary transverse deficiency and buccal lingual inclination of the posterior teeth8. (bvsalud.org)

[ 2 ] After gradual expansion over the course of 2 months, sufficient expanded skin was present to cover a cartilaginous reconstruction of a traumatic defect of the external ear. (medscape.com)
Permanent expanders with remote ports that can be removed in the office with the patient under local anesthesia when expansion is complete also have been developed for breast reconstruction . (medscape.com)
Tissue Expansion is most often used for breast reconstruction , a procedured following breast removal, and for repairing damaged or scarring of the skin due to birth defects or trauma. (uofmhealth.org)
Without tissue expansion, other procedures are performed to use existing skin in other parts of the body for reconstruction. (uofmhealth.org)
In a breast reconstruction procedure, a tissue expander (a temporary breast implant device) is sometimes put in place and inflated with saline to prepare (shape and enlarge) the recipient site (implant pocket) to receive and accommodate the breast implant prosthesis. (wikipedia.org)
Bilateral Breast reconstruction using Tissue Expansion. (shoenplasticsurgery.com)
Depending on the patient's needs and goals, reconstruction can be achieved using either the patient's own tissue or implants to create a natural look. (munsonhealthcare.org)
Tissue expansion is a technique used to enlarge an area of skin for use in reconstruction. (munsonhealthcare.org)
Tissue expansion is used for breast reconstruction. (medlineplus.gov)
3. The participant needs tissue expansion as part of breast reconstruction treatment, which may include immediate reconstruction. (who.int)
4. Clinical condition to allow reverse expansion breast reconstruction, at the investigator's discretion. (who.int)

Clonal expansion and activation of tissue-resident memory-like Th17 cells expressing GM-CSF in the lungs of severe COVID-19 patients. (uni-kiel.de)
Multiple copies of identical HIV genomes are found in all tissues, indicating that clonal expansions are not only common in blood but also in anatomical sites. (mendeley.com)

Working independently, Radovan and Austad both developed silicone tissue expanders in 1975. (medscape.com)
At this time, the FDA ruling does not affect tissue expanders because they are filled with salt water, not silicone gel, and not permanent placements. (apunjabi.com)
Traditionally, placement of tissue expanders has been in the subcutaneous and intramuscular planes. (nebraska.edu)
We present a detailed review of the literature regarding the use of tissue expanders in the management of giant omphaloceles with specific emphasis on the intra-abdominal technique of placement. (nebraska.edu)

Until recently, surgeons were limited to skin flaps and skin grafts to reconstruct damaged tissue. (plasticsurgery.org)
Using tissue expansion instead of existing skin, like flaps or skin grafts, usually leads to better outcomes. (uofmhealth.org)

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The growth of tissue is permanent, but will retract to some degree when the expander is removed. (wikipedia.org)
Once the new skin has reached its ideal size the tissue expander is removed and the new skin is redistributed, replacing the damaged area of skin. (uofmhealth.org)

citation needed] Tissue expansion has been used on the scalp for treating scalp scarring and baldness, in lieu of hair transplantation when there is insufficient donor hair to transplant on the scar or the scar tissue is not vascularized to support hair growth. (wikipedia.org)
For instance, in a patient who had melanomas removed from the scalp resulting in alopecia defects (hair loss), tissue expansion can be used to allow for the removal of scars and complete hair coverage. (wikipedia.org)
Areas of significant scarring and/or tissue atrophy, which is likely to make hair grafting unsuccessful, are best excised and replaced by normal expanded scalp skin. (wikipedia.org)
It is also an option for repairing or replacing areas of the scalp, where hair growth makes it difficult to replace lost tissue with skin from other areas of the body. (plasticsurgery.org)
Usefulness of scalp expansion for cranioplasty in a case with postinfection large calvarial defect: a case report. (prolekare.cz)
Tissue expansion is ideal for scalp repair because the stretched skin on the scalp retains normal hair growth. (apunjabi.com)
Following tissue expansion, the repaired scalp looks very natural. (apunjabi.com)

The two main indications for choosing tissue expansion over hair grafting are the size and shape of the defect relative to potential supply of donor hair, and the quality and thickness of the scar tissue. (wikipedia.org)
Often, tissue expansion is done before reconstructive burn surgery , using the new skin to replace scar tissue at the burn injury site. (uofmhealth.org)
Scar tissue forms as skin heals after an injury (such as an accident) or surgery. (medlineplus.gov)
Surgery removes extra scar tissue. (medlineplus.gov)
8. Participants who do not have adequate tissue at the intended site for expansion, at the surgeon's discretion, due to previous radiotherapy, ulceration, vascular involvement, history of impaired wound healing, or mastectomy scar deformity. (who.int)

A new technique has been presented that results in an acceleration of delayed primary healing with full thickness skin and subcutaneous tissue coverage. (who.int)

citation needed] In other applications, excess skin is grown purposely by expansion on the back or the buttocks, so that it can be harvested later for transplantation to another site where skin was lost due to trauma, extensive wounds, surgery, burns, etc. (wikipedia.org)
This study should be viewed as an initial effort to understand the role of intraoperative tissue expansion in reconstructive surgery. (northwestern.edu)
Hochman, M, Branham, G & Regan Thomas, J 1992, ' Relative Effects of Intraoperative Tissue Expansion and Undermining on Wound Closing Tensions ', Archives of Otolaryngology--Head and Neck Surgery , vol. 118, no. 11, pp. 1185-1187. (northwestern.edu)
Adetayo, OA , Aka, AA & Ray, AO 2012, ' The use of intra-abdominal tissue expansion for the management of giant omphaloceles: Review of literature and a case report ', Annals of Plastic Surgery , vol. 69, no. 1, pp. 104-108. (nebraska.edu)
Bebawi removed Rodriguez's left breast in April 2015, but a post-surgery review from the excised tissue discovered that there was no cancer, the lawsuit said. (plasticsurgerypractice.com)

The development of tissue expansion has added another technique to the armamentarium of the head and neck surgeon for management of defects that cannot be closed primarily without undue tension. (medscape.com)
As a result of tissue expansion, the treatment of alopecia has been revolutionized, and the ability to treat other cutaneous defects of the head and neck has been greatly improved. (medscape.com)
the fat-graft transfer approach augments the size and corrects contour defects of the breast hemisphere with grafts of the adipocyte fat tissue , drawn from the person's body. (wikipedia.org)
Tissues that are traumatized, irradiated, or infected surround many of these defects. (medscape.com)

Stretching the skin beyond normal expansion invokes several mechanotransduction pathways which increase mitotic activity and promote collagen synthesis. (wikipedia.org)
Mitotic activity in the epidermis is increased during expansion. (medscape.com)

Shown here is a bilateral breast, staged with tissue expander and implants after a bilateral mastectomy. (drspiro.com)

The pericranium is composed of dense connective tissue tightly affixed to calvarial bone by Sharpey fibers. (medscape.com)

Skin expansion is a common surgical procedure to grow extra skin through controlled mechanical overstretch. (wikipedia.org)
Tissue expansion is a relatively straightforward procedure that enables the body to "grow" extra skin for use in reconstructing almost any part of the body. (plasticsurgery.org)
If your doctor is recommending tissue expansion, this will give you a basic understanding of the procedure-when it can help, how it's performed, and what results you can expect. (plasticsurgery.org)
Tissue Expansion is a procedure performed to promote the growth of healthy supplementary skin used for the replacement of damaged skin. (uofmhealth.org)
BRAVA® Expansion is a non-surgical procedure that uses negative pressure to gently expand the skin and tissue of the breasts. (advancedreconstruction.com)
One of the key advantages of BRAVA® Expansion is that it is a non-surgical procedure. (advancedreconstruction.com)
In some cases, BRAVA® Expansion may be followed by a fat grafting procedure to enhance and refine the breast shape further. (advancedreconstruction.com)
You may have concerns about the use of a silicone tissue expander in this procedure because of the Food & Drug Administration's (FDA) limitations on silicone breast implants. (apunjabi.com)

9. Inadequate chest wall tissue due to damage caused by radiotherapy, tight skin grafts, or radical resection of the pectoralis major muscle. (who.int)

The device consists of domes that gently create suction and apply tension to the breast tissue, promoting expansion and growth. (advancedreconstruction.com)
Dr. Smith treats excess breast tissue in men using a variety of techniques, including liposuction and tissue removal. (munsonhealthcare.org)

In the context of β cell replacement therapy for diabetes, de Koning and colleagues describe a 3D culture platform that supports ex vivo expansion of human pancreatic tissue as organoids. (prinsesmaximacentrum.nl)

By tracking T cell clones across tissues, we identified clonally expanded tissue-resident memory-like Th17 cells (Trm17 cells) in the lungs even after viral clearance. (uni-kiel.de)
85%) of these expanded clones are shared across multiple tissues. (mendeley.com)

Collectively, these results highlight that adipocyte GR negatively controls AT expansion and metabolic health through the down-regulation of the major angiogenic effector VEGFA and inhibiting vascular network development. (c3m-nice.fr)

However, treatment of solid tumors remains limited due to insufficient NK cell tumor infiltration, and it is unknown whether large expansions of adaptive-like NK cells that are equipped for tissue residency and tumor homing exist in peripheral tissues. (scilifelab.se)
The clinical manifestations of IgG4-RD are usually tumor-like masses or organ enlargement, which result from dense tissue infiltration by immune cells and expansion of the extra-cellular matrix. (msdmanuals.com)
5. Tumor residues in or near the area where tissue expansion is performed. (who.int)

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We specifically questioned the relative effects of intraoperative tissue expansion and undermining on wound closing tensions in an animal model. (northwestern.edu)
Our data showed statistically significant reduction in the force required to close a wound after acute intraoperative tissue expansion when compared with baseline. (northwestern.edu)

Postoperative disrupted abdominal wall management by a new tissue expansion technique. (who.int)

Expansions of adaptive-like NK cells with a tissue-resident phenotype in human lung and blood. (scilifelab.se)
Importantly, in CORT-treated AdipoGR-KO mice, the blockade of VEGFA by a soluble decoy receptor prevented AT expansion and the healthy metabolic phenotype. (c3m-nice.fr)

Almost anyone in need of additional skin can benefit from tissue expansion-from infants to elderly men and women. (plasticsurgery.org)
Almost anyone in need of additional skin can benefit from tissue expansion. (apunjabi.com)
Your age, skin condition, medical history and other factors will help your surgeon determine if you will benefit from tissue expansion. (apunjabi.com)

Tissue expansion has also been used for the technique of foreskin restoration, which is usually non-surgical and applies tension externally using specialized devices to replace circumcised tissues with new cells. (wikipedia.org)
Men who have been circumcised stretch and apply tension to their shaft and foreskin remnants to expand and elongate tissue in efforts to produce a functional foreskin. (wikipedia.org)

We conclude that adult human pancreatic tissue has potential for expansion into 3D structures harboring progenitor cells with endocrine differentiation potential. (prinsesmaximacentrum.nl)

Other biological phenomena such as tissue inflammation can also be considered expansion (see tissue inflammation below). (wikipedia.org)

Continuum mechanics approaches can be used to model skin growth during tissue expansion and non-linear finite element methods can be used to computationally simulate different tissue growth scenarios. (wikipedia.org)

It creates skin that matches the color, texture, and thickness of the surrounding tissue, while minimizing scars and risk of rejection. (wikipedia.org)
Recent studies have demonstrated that using topical tissue expansion can reduce the need for a split thickness skin graft after harvesting a forearm free flap. (wikipedia.org)
This technique has improved the ability of the surgeon to replace lost or surgically excised tissue with neighboring tissue of similar color, texture, sensation, and thickness. (medscape.com)
When skin thickness is greater, like on the back and torso, expansion is more difficult. (uofmhealth.org)

Tissue expansion is a technique used by plastic, maxillofacial and reconstructive surgeons to cause the body to grow additional skin, bone, or other tissues. (wikipedia.org)
Non-surgical tissue expansion techniques can expand one's surviving penile skin, making it a longer tube so it can function like a foreskin. (wikipedia.org)
Expansion may be more difficult on the back, torso, or other areas where skin is thick. (plasticsurgery.org)
If the affected area is severely damaged or scarred, expansion is probably not an option, since healthy skin is the first requirement. (plasticsurgery.org)
On the other hand, skin expansion has one significant drawback - the length of time required to grow additional skin. (plasticsurgery.org)
Skin expansion can produce some remarkable results. (plasticsurgery.org)
New skin is generated during the process so that a net gain of tissue results. (medscape.com)
Tissue expansion is accomplished by placing a balloon like expander underneath the skin near the damaged region. (uofmhealth.org)
Since healthy skin is the primary requirement, expansion is usually not an option for areas where the skin is severely damaged or scarred. (uofmhealth.org)
Tissue expansion allows for the growth of new skin. (uofmhealth.org)
The domes apply gentle suction, which causes the skin and tissue to expand. (advancedreconstruction.com)

Although the number of transplantations each year has grown rapidly over the past two decades, the demand for transplantation using human cells, tissues and organs has also increased significantly, resulting in a continuing shortage of human material, particularly organs. (who.int)
As few countries are near to being self- sufficient in the provision of cells, tissues and organs for transplantation, new ways have been sought to increase the donation of human material. (who.int)
the trafficking of tissues and organs, the Secretariat has collaborated with scientific and professional bodies that are addressing the technical and ethical issues raised by various means to increase transplantation. (who.int)
Likewise, commercial trade in cells, tissues and organs - and even trafficking involving human beings who are kidnapped or lured into other countries where they are forced to be "donors" - continues to be a serious problem, particularly in countries with substantial transplant tourism. (who.int)

Extracellular matrix is a fibrillar network composed of structural (collagens) and adhesion (fibronectin) proteins crucial for tissue architecture and biological pathway Histol Histopathol 27:1515-1528, 2012 . (springer.com)
The extracellular matrix is essential for the architecture of the tissue and a myriad of associated biological functions. (springer.com)

the technique of tissue expansion, based upon the application of this observation, has provided great advantages to the surgeon and patient. (medscape.com)
Throughout the course of BRAVA® Expansion, regular follow-up appointments with your surgeon will be scheduled to monitor your progress. (advancedreconstruction.com)

Rapid maxillary expansion is generally contra-indicated in patients with incomplete bone formation, and is only used as an alternative in those with advanced skeletal age. (bvsalud.org)
Rapid maxillary expansion (RME) is often used to improve orthodontic results by increasing the maxillary transverse dimension in young patients 1-6 . (bvsalud.org)
The patient´s age is considered as the fundamental basis for distinguishing either the use of rapid maxillary expansion or surgically assisted rapid palatal expansion 4,8 . (bvsalud.org)
This study aims to review available literature, and to present a case of rapid maxillary expansion (RME). (bvsalud.org)

Here, we show that human lung and blood contains adaptive-like CD56brightCD16- NK cells with hallmarks of tissue residency, including expression of CD49a. (scilifelab.se)
Expansions of adaptive-like lung tissue-resident NK (trNK) cells were found to be present independently of adaptive-like CD56dimCD16+ NK cells and to be hyperresponsive toward target cells. (scilifelab.se)
Given their tissue-related character and hyperresponsiveness, human lung adaptive-like trNK cells might represent a suitable alternative for therapies targeting solid tumors. (scilifelab.se)
Interestingly, gene expression profiling revealed that ALDH hi cells are closer to human fetal pancreatic tissue compared with adult pancreatic tissue. (prinsesmaximacentrum.nl)

Surgically assisted rapid palatal expansion is an alternative to achieve effective maxillary expansion in skeletally mature patients 1,3-4 . (bvsalud.org)
The patient was taken to the Hospital ater to undergo surgically assisted rapid palatal expansion under general anesthesia using naso-tracheal intubation. (bvsalud.org)

Classically the fat mass expansion results with an increase in the volume (hypertrophy) and the number (hyperplasia) of adipocytes [ 5 , 6 ]. (springer.com)

Fibrosis is characterized by an excessive accumulation of extracellular matrix components which could result in tissue dysfunction. (springer.com)

Early attempts to expand living tissues first were performed by orthopaedic surgeons in the early 1900s, but the first clinical experience with tissue expansion was not described until 1957, when Neumann related the use of a rubber balloon placed subcutaneously in the postauricular region. (medscape.com)
Galen demonstrated outstanding outcomes across multiple clinical studies performed on various tissue types and diagnostic workflows 1,2,3,4,5 . (itbusinessnews.com)

Expansion of the time window for treatment of acute ischemic stroke with intravenous tissue plasminogen activator: a science advisory from the American Heart Association/American Stroke Association. (qxmd.com)

Tissue expansion generally produces excellent results when reconstructing some areas of the face and neck, the hands, arms, and legs. (plasticsurgery.org)
Our team of plastic surgeons and medical specialists guide patients through every step of the tissue expansion process to ensure the best results possible. (uofmhealth.org)
The expansion process helps to create more space for the fat graft, which can lead to better results. (advancedreconstruction.com)
Post-treatment care for BRAVA® Expansion is essential to ensure optimal healing and results. (advancedreconstruction.com)
Despite the drawbacks, tissue expansion can produce very pleasing results, and is a superior technique for its reconstructive purpose. (apunjabi.com)

If you are dissatisfied with the size or shape of your breasts and desire a non-surgical approach to breast augmentation, BRAVA® Expansion may be an ideal option for you. (advancedreconstruction.com)
Surgical removal of this extra tissue can improve your confidence and your figure. (munsonhealthcare.org)

Two--stage cranioplasty: tissue expansion directly over the craniectomy defect prior to cranioplasty. (prolekare.cz)

The core of BRAVA® Expansion involves wearing the specialized BRAVA® device on your breasts. (advancedreconstruction.com)

Anatomy3

Analytical, Diagnostic and Therapeutic Techniques and Equipment2

Psychiatry and Psychology1

Disciplines and Occupations1

Humanities1

Adipose13

Overlying the expanders1

Soft tissue13

Reconstruction11

Clonal2

Expanders4

Flaps2

20212

Expander is removed2

Scalp7

Scar5

Subcutaneous tissue1

Surgery5

Defects4

Mitotic2

Bilateral breast1

Dense connec1

Procedure8

Grafts1

Breast tissue2

Vivo Expansion1

Clones2

Adipocyte1

Tumor3

Wound11

Postoperative1

Phenotype2

Benefit from tissue3

Tension2

Differentiation1

Inflammation1

Finite1

Thickness4

Skin11

Organs4

Biological2

Surgeon2

Rapid maxillary expansion4

Cells4

Surgically2

Adipocytes1

Dysfunction1

Clinical2

Acute1

Results5

Surgical2

Defect1

Device1