• Primary aims were to compare adipose tissue distribution in adult patients with juvenile-onset DM (JDM), with matched controls. (nih.gov)
  • Secondary aims were to explore how adipose tissue distribution is associated with cardio-metabolic status (cardiac dysfunction and metabolic syndrome) in patients. (nih.gov)
  • In all participants, dual-energy X-ray absorptiometry (DXA) and echocardiography were used to measure visceral adipose tissue (VAT)(g) and cardiac function, respectively. (nih.gov)
  • Risk factors for metabolic syndrome were measured and associations with adipose tissue distribution explored. (nih.gov)
  • visceral adipose tissue. (nih.gov)
  • This study revealed in general that the level of pesticides in samples of adipose tissue was higher than that in samples of milk from any source (city or rural). (scialert.net)
  • Indeed, while the average of 2,2-bis(p-chlorophenyl)-1,1,1-trichloroethane (DDT), predominant specie and its isomers in adipose tissue was 10.02 mg kg -1 in countryside and 6.93 mg kg -1 in the city, it was respectively 0.013 and 0.019 mg kg -1 in milk. (scialert.net)
  • Adipose tissue samples revealed the presence of polychlorinated biphenyl (PCB), Hexachlorobiphenyl (HCB) in addition to pesticides which are found in the milk Average concentrations of organochlorine pesticides in milk matrix were above the Maximum Residue Limits (MRL) of WHO. (scialert.net)
  • Regarding adipose tissue, this trend was also observed, except for DDT and its metabolites whose values were far below the MRL. (scialert.net)
  • PPARα and LXRα were mainly expressed in liver, while PPARγ1 predominated in adipose tissue and large intestine. (diabetesjournals.org)
  • We found that PPARγ2 mRNA was a minor isoform, even in adipose tissue, thus causing question of its role in humans. (diabetesjournals.org)
  • Time courses and dose responses were determined for serum thyroxine (T4) and triiodothyronine (T3) levels, for 5'-DI activity in thyroid gland, liver and kidney, and for 5'-DII activity in brown adipose tissue (BAT). (nih.gov)
  • Brown adipose tissue (BAT) or brown fat makes up the adipose organ together with white adipose tissue (or white fat). (wikipedia.org)
  • Brown adipose tissue is found in almost all mammals. (wikipedia.org)
  • Brown adipose tissue is especially abundant in newborns and in hibernating mammals. (wikipedia.org)
  • In addition to heat produced by shivering muscle, brown adipose tissue produces heat by non-shivering thermogenesis. (wikipedia.org)
  • The presence of brown adipose tissue in adult humans was discovered in 2003 during FDG-PET scans to detect metastatic cancers. (wikipedia.org)
  • Using these scans and data from human autopsies, several brown adipose tissue deposits have been identified. (wikipedia.org)
  • It remains to be determined whether these deposits are 'classical' brown adipose tissue or beige/brite fat. (wikipedia.org)
  • Beige fat is the adrenergically inducible cell type that is dispersed throughout adipose tissue. (wikipedia.org)
  • Adipose tissue inflammation appears to be a risk factor for the progression of chronic kidney disease (CKD), but the effect of CKD on adipose tissue inflammation is poorly understood. (mdpi.com)
  • The purpose of this study was to clarify the involvement of uremic toxins (indoxyl sulfate (IS), 3-indoleacetic acid, p-cresyl sulfate and kynurenic acid) on CKD-induced adipose tissue inflammation. (mdpi.com)
  • 1990. Organochlorine compounds in human adipose tissue from north Texas. (cdc.gov)
  • 1975. The effect of atmospheric levels of pesticides on pesticide residues in rabbit adipose tissue and blood sera. (cdc.gov)
  • 1981. Determination of organochlorine pesticides and metabolites in drinking water, human blood serum, and adipose tissue. (cdc.gov)
  • In an attempt to find the likely source of IFN-alpha in physiological conditions, an initial study was carried out in which the cellular distribution of immunoreactive IFN-alpha was studied in formalin fixed paraffin embedded normal adult human tissues from 38 different organs using various immunocytochemical techniques. (gla.ac.uk)
  • Tissue histiocytes from all organs in the body, with the exception of cerebral and cerebellar cortex in brain and renal cortex and medulla, stained positively for IFN-alpha. (gla.ac.uk)
  • Formalin fixed paraffin embedded tissues from these organs did show immunoreactive IFN-alpha in cells using the immunocytochemical techniques. (gla.ac.uk)
  • 39 An establishment that stores cells, tissues or organs must ensure that any of them that are untested or for which the results of tests on donor blood samples are positive or reactive for transmissible disease agents or markers or are unavailable are segregated from all other cells, tissues and organs. (gc.ca)
  • 41 (1) A source establishment that distributes cells, tissues or organs under section 40 must keep a copy of the notice of exceptional distribution in its records. (gc.ca)
  • ii) if the cells, tissues or organs were imported, the establishment that imported them. (gc.ca)
  • 2) If the establishment that receives a notice under subsection (1) is the establishment that imported the implicated cells, tissues or organs, it only has to notify the source establishment. (gc.ca)
  • Open to individuals involved or interested in the banking of cells, organs, eyes, or tissues who support our objectives, policies, and ethical standards. (aatb.org)
  • Here we describe the use of CODEX to visualize the phenotypic and spatial heterogeneity of murine tissue -resident macrophages in several organs, and a pipeline to characterize their cellular microenvironments and interactions. (bvsalud.org)
  • Pneumatic micro-extrusion (PME) is a high-resolution direct-write additive manufacturing method, which has been widely utilized for the fabrication of biological tissues, structures, and organs. (asme.org)
  • Moreover, because co-registration of MRI and CT images is not performed in the MR-only workflow, clinicians can avoid registration errors that force margin increases, while exploiting MRI's exceptional soft tissue visualization to delineate the prostate and organs-at-risk. (philips.com)
  • Although previous recommendations for preventing transmission of human immunodeficiency virus (HIV) through transplantation of human tissue and organs have markedly reduced the risk for this type of transmission, a case of HIV transmission from a screened, antibody-negative donor to several recipients raised questions about the need for additional federal oversight of transplantation of organs and tissues. (cdc.gov)
  • A working group formed by the Public Health Service (PHS) in 1991 to address these issues concluded that further recommendations should be made to reduce the already low risk of HIV transmission by transplantation of organs and tissues. (cdc.gov)
  • In 1985, when tests for HIV antibody became available, screening prospective donors of blood, organs, and other tissues also began (2,3). (cdc.gov)
  • This occurrence raised questions about the need for additional federal oversight of transplantation of organs and tissues. (cdc.gov)
  • The working group concluded that, although existing recommendations are largely sufficient, revisions should be made to reduce the already low risk of HIV transmission via transplantation of organs and tissues. (cdc.gov)
  • The transplantation of human tissues, organs or cells is an established form of treatment that has been acknowledged as the best and very often only life-saving therapy for several serious and life-threatening congenital, inherited and acquired diseases and injuries. (who.int)
  • In June 2018, the Secretariat established the WHO Task Force on Donation and Transplantation of Human Organs and Tissues as an advisory group composed of experts from all WHO regions. (who.int)
  • Transplantation of tectal tissue in rats. (edu.au)
  • Dive into the research topics of 'Transplantation of tectal tissue in rats. (edu.au)
  • http://www.researchandmarkets.com/research/f7thqr/organ_and_tissue ) has announced the addition of the "Organ and Tissue Transplantation - Global Strategic Business Report" report to their offering. (prnewswire.com)
  • This report analyzes the worldwide markets for Organ and Tissue Transplantation in Number of Procedures. (prnewswire.com)
  • The global and regional markets (except the US) for 'Organ and Tissue Transplantation' in this report are analyzed by the following Product Segments - Organ Tranplantation (Heart, Kidneys, Liver, Pancreas, and Lungs). (prnewswire.com)
  • She has dedicated her decades-long career to developing an ex vivo tissue engineering technique which offers a safer, more precise way of cultivating skeletal, heart, lung, and vascular tissue for either transplantation, disease modelling, or drug testing. (prweb.com)
  • Online learning and education surrounding all aspects of tissue donation, tissue banking, research, and transplantation. (aatb.org)
  • In May 2010, the Sixty-third World Health Assembly adopted resolution WHA63.22,1 in which it endorsed the updated WHO Guiding Principles on Human Cell, Tissue and Organ Transplantation and provided strategic directions to support progress in human organ, tissue and cell donation with the aim of maximizing the benefits of transplantation, meeting the needs of recipients, protecting donors and ensuring the dignity of all involved. (who.int)
  • The benefits of human tissue transplantation can be seen in both children and adults, including in survival rates following severe burn trauma, recovery of movement, closure of chronic wounds, rehabilitation of heart function and restoration of sight. (who.int)
  • Corneal disease (scarring or perforation) can be successfully addressed through transplantation in 80% of affected individuals.3 Tissue transplantation allows many recipients to return to economically productive lives and promotes their independence. (who.int)
  • Thus, the availability of and access to human tissues for transplantation remains essential. (who.int)
  • The concentrations of metals in the tissues were measured using an Inductively Coupled Plasma-Atomic Emission Spectrophotometer (ICP-AES) and an ICP-Mass Spectrometer (ICP-MS). Metallothionein levels were determined using Differential pulse polarography. (unboundmedicine.com)
  • Comparison between the mean concentrations of the elements in muscle tissue and existing guidelines indicate that in nearly all cases, the concentrations were well below permissible levels for human consumption. (unboundmedicine.com)
  • The tissue concentrations were quantified using a HPLC method, with a quantification limit of 25 mg.kg-1 for muscle, fat and lung and of 50 mg.kg-1 for liver and kidney. (upv.es)
  • The experimental results show that in rabbits flumequine reaches effective tissue concentrations rapidly after oral treatment. (upv.es)
  • Considering the tissue concentrations observed after the repeated administration it can be concluded that at the dose employed (15 mg.kg-1) potentially effective drug concentrations are recorded only in the liver and the kidney. (upv.es)
  • Cerebellin was concentrated in synaptosomal preparations of rat brain, and its subcellular distribution pattern in rat brain was identical to that of two other known synaptosomal peptides, vasoactive intestinal polypeptide and substance P. Studies with superfused cerebellar synaptosomes and slices of rat cerebellum and hypothalamus demonstrated calcium-dependent cerebellin release when stimulated by high potassium concentrations as well as the addition of the calcium ionophore A23187. (ox.ac.uk)
  • After equilibrium, drug concentrations in tissues and in extracellular fluids are reflected by the plasma concentration. (msdmanuals.com)
  • Concentrations of Immunoglobulins in Granulation Tissue from Pockets of Periodontosis and Periodontitis Patients. (dtic.mil)
  • It was felt that research should be continued in this area, and a study was initiated to determine the IgA, IgG, and IgM concentrations in the granulation tissue removed from deep infrabony pockets of patients with periodontosis and advanced periodontitis. (dtic.mil)
  • It was concluded that there were increases in both whole blood and tissue total Se concentrations as a result of dietary supplementation with high dose of SY. (reading.ac.uk)
  • The Gini index (coefficient) characterises inequalities of distributions, and is used in a novel way to describe the distribution of the expression of each transporter among the different tissues and cell lines. (biorxiv.org)
  • These observations are important as they illustrate the incredible self-organizing ability of biological tissues, a property that enables them to withstand stressful conditions. (pasteur.fr)
  • 42 A source establishment that distributes a cell, tissue or organ under section 40 before the donor suitability assessment is complete must, after the distribution, complete the assessment, carry out any other appropriate follow-up testing and notify the relevant transplant establishment of the results. (gc.ca)
  • A 1991 investigation determined that several recipients had been infected with HIV by an organ/tissue donor who had tested negative for HIV antibody at the time of donation (4). (cdc.gov)
  • The demonstration of immunoreactive IFN-alpha in formalin fixed paraffin embedded normal adult human tissues prompted other studies. (gla.ac.uk)
  • These findings were almost identical to those seen in adult tissues. (gla.ac.uk)
  • In adult humans, muscle mass may change due to exercise, and fat distribution may change due to hormone fluctuations. (wikipedia.org)
  • The mechanisms that regulate the ability of epithelia to maintain their integrity in contexts involving large numbers of eliminated cells remain poorly understood, despite the fact that this situation occurs regularly during embryogenesis or the maintenance of adult tissues. (pasteur.fr)
  • In visceral muscles of the larval midgut and adult testis, lipins present a sarcomeric distribution. (unesp.br)
  • Immunoreactive IFN-alpha was also demonstrated in parenchymal cells of thyroid gland, choroid plexus in brain, anterior pituitary gland and adrenal gland in the fetal and infant tissues. (gla.ac.uk)
  • STC2-A was detected in a variety of tissues, including pituitary, with most abundant immunoreaction in kidney cells and gill rakers and the CS was negative. (ualg.pt)
  • Vunjak-Novakovic's pioneering technique involves creating living biological grafts by growing a new piece of tissue ex vivo from a patient's own cells, entirely eliminating these problems. (prweb.com)
  • In the 1980s, when Vunjak-Novakovic began her career, the mainstream approach was to combine cells and biomaterials, and insert them into the body, with the intention of this transplant finding a way to regenerate tissues. (prweb.com)
  • The researcher, herself inspired as a child by the scientific excellence of fellow Serbian Nikola Tesla, pioneered an alternative: growing cells in a laboratory by carefully controlling the external environments - the temperature, pH, nutrients, oxygen, growth factors and physical forces - to influence the type of tissue they develop into, and then implanting this tissue into the body. (prweb.com)
  • Co- Detection by Indexing (CODEX), a multiplexed imaging technique , allows the simultaneous detection of multiple membrane and cellular markers that enable the accurate identification of tissue -resident hematopoietic and non-hematopoietic cells , while conferring spatial information at a single- cell level. (bvsalud.org)
  • Both adipocytes and brown adipocyte may be derived from pericytes, the cells which surround the blood vessels that run through white fat tissue. (wikipedia.org)
  • To enable tissue renewal, human tissues constantly eliminate millions of cells, without jeopardizing tissue integrity, form and connectivity. (pasteur.fr)
  • Scientists from the Institut Pasteur and the CNRS today revealed a new process which allows eliminated cells to temporarily protect their neighbors from cell death, thereby maintaining tissue integrity. (pasteur.fr)
  • The scientists observed that when the mechanism is deactivated, the simultaneous elimination of several neighboring cells compromises tissue integrity. (pasteur.fr)
  • Tissue renewal involves the formation of new cells by cell division and the elimination of dead cells. (pasteur.fr)
  • We already knew that this pathway plays a key role in regulating cell survival in epithelial tissue, but we were surprised to observe such protective dynamics between cells, " comments Romain Levayer, Head of the Cell Death and Epithelial Homeostasis Unit at the Institut Pasteur and last author of the study. (pasteur.fr)
  • The scientists' research also shows that inhibiting this protective mechanism has a drastic effect on epithelial tissue: cell elimination becomes random and neighboring cells can be eliminated simultaneously, leading to repeated losses of connectivity. (pasteur.fr)
  • The elimination of groups of neighboring cells is never observed in epithelial tissue in normal conditions, when the EGFR-ERK pathway is not deliberately inhibited, even if a large number of cells are eliminated. (pasteur.fr)
  • Surprisingly, epithelial tissue is highly sensitive to the spatial distribution of eliminated cells. (pasteur.fr)
  • The scientists' observations confirm that tissues need to develop mechanisms preventing the elimination of neighboring groups of cells. (pasteur.fr)
  • Release of damaged cells and tissue debris occurs upon injury. (medscape.com)
  • Tissues and Cells. (lu.se)
  • Connective Tissue is a mature, polished collection that evolves from its predecessor in pleasing and sometimes surprising ways. (saltpublishing.com)
  • Using a quantitative and sensitive reverse transcription (RT)-competitive polymerase chain reaction (PCR) assay, we determined the distribution and relative mRNA expression of the four PPARs (α, β, γ1, and γ2) and liver X receptor-α (LXRα) in the main tissues implicated in lipid metabolism. (diabetesjournals.org)
  • Distribution is generally uneven because of differences in blood perfusion, tissue binding (eg, because of lipid content), regional pH, and permeability of cell membranes. (msdmanuals.com)
  • In contrast to white adipocytes, which contain a single lipid droplet, brown adipocytes contain numerous smaller droplets and a much higher number of (iron-containing) mitochondria, which gives the tissue its color. (wikipedia.org)
  • Perland and Fredriksson, 2017 ) or the pharmaceutical drug substrates of these transporters, and one clue to this may be to understand their differential tissue distribution. (biorxiv.org)
  • Conversely selenomethionine was the predominat selenized amino acid in cardiac and skeletal muscle (Longissimus Dorsi, and Psoas Major) tissues in HSY animals, although the same trend was not apparent for control lambs in which SeCys was the predominant selenized amino acid. (reading.ac.uk)
  • In the first of these studies the cellular distribution of immunoreactive IFN-alpha was studied in formalin fixed paraffin embedded normal human autopsy tissues from 32 fetuses (7-42 weeks gestation) and 20 infants (aged from a few hours to 24 months). (gla.ac.uk)
  • Updates to acceptable fixed autopsy tissue specimens for submission to CDC's Infectious Diseases Pathology Branch. (cdc.gov)
  • Unfortunately, even clinically approved focal DDSs lead to limited intratumoral distribution of the drug (therapeutic penetration depth of only 1-2 mm) that compromises their clinical effectiveness. (cityofhope.org)
  • values were 26, 16, 8 and 3 times higher in skeletal muscle, liver, heart and kidney tissue of HSY lambs when compared to controls. (reading.ac.uk)
  • Selenocysteine was the predominant selenized amino acid in glandular tissues, such the liver and kidney. (reading.ac.uk)
  • The presence of interferon-alpha (IFN-alpha) in human tissues has been described extensively in viral infections. (gla.ac.uk)
  • Some drugs distribute mostly into fat, others remain in extracellular fluid, and others are bound extensively to specific tissues. (msdmanuals.com)
  • Many basic drugs (eg, amphetamine , meperidine ) are extensively taken up by tissues and thus have an apparent volume of distribution larger than the volume of the entire body. (msdmanuals.com)
  • In a separate study an attempt was made to extract, detect and quantify IFN-alpha in human tissues using protein extraction and an immunoradiometric assay kit for the detection of IFN-alpha. (gla.ac.uk)
  • In biological studies it is often important to detect and quantify certain trace elements and to visualize their distribution within the tissue. (tofwerk.com)
  • The area at half maximum (FAHM) was calculated from angle histograms to quantify orientation distribution. (lu.se)
  • In this study, we investigated the metabolic stability, metabolite production, metabolic pathways and plasma protein binding (PPB) of FHND6081 along with its absorption, tissue distribution, excretion (ADME) and pharmacokinetics (PK) in animals. (scienceopen.com)
  • Overview of Pharmacokinetics Pharmacokinetics, sometimes described as what the body does to a drug, refers to the movement of drug into, through, and out of the body-the time course of its absorption, bioavailability, distribution. (msdmanuals.com)
  • We analyse two comprehensive transcriptome datasets from human tissues and human-derived cell lines in terms of the expression profiles of the SLC and ABC families of membrane transporters. (biorxiv.org)
  • The levels of organochlorine residues in 40 samples of milk and 20 human adipose tissues from two locations in the northern of Côte d Ivoire were determined. (scialert.net)
  • Human breast milk samples (40 samples) and adipose tissues (20 samples) were collected from mothers (17 to 56 years old, average age 30) living in two different locations in the north of Côte d Ivoire (Korhogo and Sinématiali) from 2004 to 2007. (scialert.net)
  • Over her lifetime, Gordana Vunjak-Novakovic has made a major contribution to tissue engineering, one of the most promising ways to prolong the human lifespan and improve quality of life," said EPO president António Campinos, announcing the 2021 EPO Award finalists. (prweb.com)
  • The only accreditation program for tissue establishments, recognizing the highest commitment to the quality and safety of donated human tissue. (aatb.org)
  • Human epithelia are tissues found in several parts of the body (such as the epidermis and internal mucosa). (pasteur.fr)
  • While the development of xenografts (products of animal origin) and bioengineered alternatives is advancing, to date they cannot fully mimic or replace all human-sourced tissues on an equivalent basis. (who.int)
  • Metabolism and excretion occur simultaneously with distribution, making the process dynamic and complex. (msdmanuals.com)
  • The global hemostasis & tissue sealing agents market size was valued at USD 6.13 billion in 2021 and is anticipated to expand at a compound annual growth rate (CAGR) of 8.8% during the forecast period. (express-press-release.net)
  • The general shape or figure of a person is defined mainly by the molding of skeletal structures, as well as the distribution of muscles and fat . (wikipedia.org)
  • For poorly perfused tissues (eg, muscle, fat), distribution is very slow, especially if the tissue has a high affinity for the drug. (msdmanuals.com)
  • The resulting infiltration of tissues by the leukocytes, plasma proteins, and fluid causes the redness, swelling, and pain that are characteristic of inflammation. (medscape.com)
  • The widespread distribution of stcs in fish tissues supports pleiotropic roles. (ualg.pt)
  • Cerebellin has therefore a widespread distribution and fulfils two criteria for a neurotransmitter, in that it is found in brain synaptosomes and shows calcium dependent, depolarization-induced release from nervous tissues and isolated nerve endings. (ox.ac.uk)
  • The developed method will allow for detection of scaffold pores, thus quantification of pore size distribution, and ultimately assessment of the dimensional accuracy of bone tissue scaffolds. (asme.org)
  • Fetal tissues are "germ free" while the infants had been exposed to a normal microbial flora. (gla.ac.uk)
  • We have examined the maturation of tectal tissue transplanted from fetal rats to the midbrain of newborns and have characterized the distribution of host retinal and cortical afferents within the transplants. (edu.au)
  • Subsequently, comprehensive records of the natural or pathologic distribution of the pancreatic β-cell mass (here β-cell volume (BCV) will be used since it better adheres to the principle of detection), taking the entire pancreatic volume into account, are essentially lacking. (nature.com)
  • Many acidic drugs (eg, warfarin , aspirin ) are highly protein-bound and thus have a small apparent volume of distribution. (msdmanuals.com)
  • The extent of drug distribution into tissues depends on the degree of plasma protein and tissue binding. (msdmanuals.com)
  • Notably, this is not the same as the presence of Myf5 protein, which is involved in the development of many tissues. (wikipedia.org)
  • They are characterized by their bioaccumulation properties in the fatty parts of biological beings, such as blood, breast milk and fatty tissues via the food chain ( Smith and Gangolli, 2002 ). (scialert.net)
  • Guidelines for AATB accredited establishments to use in conjunction with the Standards for Tissue Banking and the Standards for Non-Anatomical Donation. (aatb.org)
  • and recall of stored tissues from donors found after donation to have been infected. (cdc.gov)
  • Because bone tissue is constantly renewing itself, the animal scaffold will eventually be replaced with the patient's own bone. (prweb.com)
  • Highly significant size-related differences were found in the levels of Cd, Cu and metallothionein in the selected tissues of the shrimp species. (unboundmedicine.com)
  • This is then fed into a microfabrication device to carve a piece of pig or cattle bone matrix into the same shape, creating a scaffold for the new bone tissue to grow in. (prweb.com)
  • In pursuit of this goal, the objective of the work is to forward an image-based method for the characterization of the pore size distribution as well as the dimensional properties of bone tissue scaffolds, fabricated using the PME process. (asme.org)
  • This study investigates the distribution of three trace elements (Cd, Cu and Zn) in tissues (exoskeleton, abdominal muscle and hepatopancreas) of two shrimp species (Penaeus merguiensis and Penaeus semisulcatus). (unboundmedicine.com)
  • At Búzios Island, on the northern coast of São Paulo State, where the abundance of T. tagusensis is particularly high, some colonies are displaying tissue necrosis, a phenomenon never reported for this invasive nor any other azooxanthellate coral species. (nature.com)
  • Furthermore, distribution of total Se and Se species differed between both treatment designation and tissue type. (reading.ac.uk)
  • f) the time and date of the written authorization of the distribution and a copy of the authorization signed by the transplant physician or dentist. (gc.ca)
  • 2) The transplant establishment must keep a copy of the notice of exceptional distribution in its records. (gc.ca)
  • However, even in a small animal like the mouse, the predominant model system for studies of diabetes and metabolic stress, the ability to obtain a detailed spatial and quantitative view of the pancreatic β-cell mass distribution has been limited. (nature.com)
  • In regards to Zn and Cu accumulation in edible (muscle) tissues of P. merguiensis, optimum conditions for frozen storage is -30 degrees C as ice-frozen, and in terms of short-term storage, 1-day refrigeration is recommended. (unboundmedicine.com)
  • The variations in pH values measured in the muscle of P. merguiensis in different storage conditions showed a similar trend with metallothionein, Zn and Cu. In contrast, it appears that cadmium is transported from muscle to the other tissues. (unboundmedicine.com)
  • The needle itself may provide drainage and a release of pressure, and it may also mechanically disrupt the scar tissue in the muscle. (medscape.com)
  • We present ex vivo optical tomographic data sets of the full β-cell mass distribution in cohorts of obese ob/ob mice and their lean controls, together with information about individual islet β-cell volumes, their three-dimensional coordinates and shape throughout the volume of the pancreas between 4 and 52 weeks of age. (nature.com)
  • To address the current lack of combined topological and quantitative information of the BCV distribution in obese ( ob/ob ) mice and their healthy lean controls, we recently assessed the full BCV distribution at 4, 8, 17, 26 and 52 weeks of age by OPT imaging analyses 12 (for schematic overview of the assay design see Fig. 1 ). (nature.com)
  • By contrast, the Gini coefficients for ABC transporters tend to be larger in cell lines than in tissues, implying that some kind of a selection process has taken place. (biorxiv.org)
  • In its traditional CT-MRI simulation and planning workflow, Ingenia has been invaluable for its superb, tunable soft-tissue contrast, particularly for planning prostate cancer cases, according to Prof. Heikki Minn, MD, Radiation Oncologist at TYKS. (philips.com)
  • Cerebellin-like peptide: tissue distribution in rat and guinea-pig and its release from rat cerebellum, hypothalamus and cerebellar synaptosomes in vitro. (ox.ac.uk)
  • Relating in vitro to in vivo exposures with physiologically based tissue dosimetry and tissue response models. (cdc.gov)
  • Quantitative parameters related to fiber orientation and crimping were evaluated as potential markers of tissue degeneration. (lu.se)
  • Further work is needed to establish quantitative parameters that relate to tissue degeneration, but this imaging technique is promising for future studies of meniscus structure and biomechanical response. (lu.se)
  • Four stanniocalcin genes in teleost fish: structure, phylogenetic analysis, tissue distribution and expression during hypercalcemic challenge. (ualg.pt)
  • Special emphasis in this study was placed on evaluating the effects of storage conditions on redistribution of the elements and moreover the potential roles of metallothionein in tissue redistribution. (unboundmedicine.com)
  • Results indicate a wide variety of bacteria associated with healthy colonies and an even higher diversity associated with those corals presenting tissue necrosis, which displayed nearly 25% more microorganisms. (nature.com)
  • Comparing the microbiome from healthy corals to those in early tissue necrosis suggests 21 potential pathogens, which might act as the promoters of such disease. (nature.com)
  • Importantly, the impact to coral microbiomes by fish feces under higher temperatures appeared to inhibit wound healing in corals, as percentages of tissue recovery at the site of feces deposition were lower at 30°C compared to 26°C. Lower percentages of tissue recovery were associated with greater relative abundance of several bacterial lineages, with some of them found in surgeonfish feces (i.e. (frontiersin.org)