Tissue cells differentiate. Medical search. Frequent questions

In addition to osteocyte-like cells, the spheroids consisted of osteoblasts at various differentiation stages surrounded by a rim of cells resembling lining cells. (ntnu.no)
This resemblance to native bone indicates a model system with potential for studying osteocyte-like cell differentiation, cross-talk between bone cells, and the mineralization process in a bonelike structure in vitro without artificial scaffolds. (ntnu.no)
Our results now suggest that 4-MU treatment of MSC not only affects the formation of SG via increased levels of O-linked glycosylation of cellular proteins but also that MSC cultivated under osteogenic stimulation develop SG, which in turn support MSC differentiation into osteogenic precursor cells. (europa.eu)
Coexisting foamy and nonfoamy adenocarcinoma with glandular differentiation devoid of basal cell lining is helpful in clarifying their malignant nature. (medscape.com)
MSCs have multilineage differentiation potential, allowing them to differentiate, for example, into chondrocytes and osteoblasts, the key cells from the two tissues that constitute the osteochondral unit. (hindawi.com)
Stem cells are defined by their capacity for self-renewal and multilineage differentiation, making them uniquely situated to treat a broad spectrum of human diseases. (articlecity.com)
And TGF-β, just going back to that, is specific to cellular function in terms of cell growth, proliferation, differentiation. (chiroeco.com)
BioTek's Cytation™ 5 Cell Imaging Multi-Mode Reader was used to monitor spheroids in the inserts during the differentiation process using the brightfield channel, as well as to capture fluorescent images to verify protein marker expression and chondrocyte differentiation. (selectscience.net)
This differentiation of stem cells to a cell type that performs a specific function is thought to be irreversible. (medicalnewstoday.com)
I was experimenting with different molecules that would stick cells together and stimulate stem cell differentiation and cartilage formation. (tecan.com)
They proved to be very useful at triggering stem cell differentiation into cartilage, and that was the first idea Kramer and I intended to pursue. (tecan.com)
Despite increasing refinement of differentiation protocols and standardization of the transplanted neural precursors, the transcriptomic analysis of cells in the transplant after its full maturation in vivo has not been thoroughly investigated. (lu.se)
Recent advances in live imaging and genetics of mammalian division, movement and cell differentiation leading to development which integrate observations of biochemical tissue formation [14 ]. (lu.se)
At these sites, which are a compound of stromal cells, extracellular matrix and soluble factors, complex molecular interactions that maintain the essential properties of stem cells occur, such as self-renewal and differentiation into multiple lineages, according to the organism's needs. (bvsalud.org)
Firstly, we present a robust 2-week protocol for the differentiation of human pluripotent stem cells (PSCs) into forebrain neural progenitor cells. (lu.se)

If the cancerous tissue looks very different from healthy tissue, it is called "poorly differentiated" or a "high-grade tumor. (cancer.net)
In contrast, poorly differentiated or undifferentiated tumors look abnormal, unlike typical body tissues. (medicalnewstoday.com)
the other two had poorly differentiated or clear cell carcinomas. (cdc.gov)

They travel around a person's body in the blood and lymphatic system to other locations, where they may grow and form new tumors in the surrounding tissues. (medicalnewstoday.com)
Doctors may also describe tumors as well-differentiated if they look similar to typical body tissues. (medicalnewstoday.com)
Unfortunately, the squished-nosed dogs of the world are not the only ones who get mast cell tumors. (dogsnaturallymagazine.com)
What Are Mast Cell Tumors? (dogsnaturallymagazine.com)
Mast cell tumors (MCTs) happen mostly on the skin but sometimes in the internal organs . (dogsnaturallymagazine.com)
We are using human cells to make the tumors, which yields better data and spares lab animals. (tecan.com)
The cancer stem cell theory holds that tumors also contain stem-like cells that drive tumor growth and metastasis formation. (medscape.com)
Tumors, like the tissues from which they originate, contain a unique SC population that is capable of self-renewal and of sustaining tumor growth indefinitely. (medscape.com)

Others are interested in how tissues grow into complex and specific shapes, eventually forming organs. (encyclopedia.com)
These stem cells come from developed organs and tissues in the body. (healthline.com)
However, there is evidence that bone marrow-derived monocytes can help replenish the tissue-resident macrophages of specific organs including the gut, the skin, and the heart ( Ginhoux and Guilliams, 2016 ). (frontiersin.org)
Cells Tissues Organs (2001) 169 (4): 347-354. (karger.com)
Understanding how stem cells behave in the niche is extremely important in order to extract these cells from their natural habitat, expand them in vitro and transplant the stem cells back to the patient, to repair and/or regenerate tissues and organs, with no risks to the individual's integrity. (bvsalud.org)
Therapies based on the application of stem cells have great potential in the prevention and treatment of several diseases, such as cancer, diabetes, cardiovascular disease, spinal cord injuries, neurological diseases such as Parkinson's and Alzheimer's, and in the regeneration of various tissues and organs. (bvsalud.org)
Transformative processes which occur in cells and tissues to produce differentiated plant organs. (bvsalud.org)

Here, we present spatial transcriptomics analysis of fully differentiated grafts in their host tissue. (lu.se)
Neutrophils, mostly in fully differentiated cells. (lu.se)

[ 7 ] Retinal endothelial cells give rise to primitive capillaries that further differentiate into mature vessels. (medscape.com)
Upon entering affected tissues, classical monocytes can further differentiate into macrophages and monocyte-derived dendritic cells (MoDCs). (frontiersin.org)
Classical "inflammatory" monocytes can give rise to non-classical "patrolling" monocytes or further differentiate into macrophages or monocyte-derived dendritic cells (MoDCs). (frontiersin.org)

During embryogenesis endothelial cells exhibit substantial plasticity that contribute to cardiac development by undergoing endothelial-to-mesenchymal transition (EndoMT). (surrey.ac.uk)
We determined the presence of EndoMT in the pulmonary vasculature in vivo and the functional effects on pulmonary artery endothelial cells (PAECs) undergoing EndoMT in vitro. (surrey.ac.uk)
Histologic assessment of patients with systemic sclerosis-associated PAH and the hypoxia/SU5416 mouse model identified the presence von Willebrand factor/α-smooth muscle actin-positive endothelial cells in up to 5% of pulmonary vessels. (surrey.ac.uk)
Our previously-obtained impressive results of highly increased C2C12 mouse myoblast adhesion to amine plasma polymers (PPs) motivated current detailed studies of cell resistance to trypsinization, cell proliferation, motility, and the rate of attachment carried out for fibroblasts (LF), keratinocytes (HaCaT), rat vascular smooth muscle cells (VSMC), and endothelial cells (HUVEC, HSVEC, and CPAE) on three different amine PPs. (nature.com)
We demonstrated the striking difference in the resistance to trypsin treatment between endothelial and non-endothelial cells. (nature.com)
Undifferentiated endothelial cells are critical to the development of retinal vessels. (medscape.com)
5 , - , 9 This loose connective tissue is composed of extracellular matrix and various types of cells: fat cells-named adipocytes, and the non-fat cells of the stromal vascular fraction that contains preadipocytes, capillary endothelial cells, infiltrating leucocytes and multipotent stem cells. (bmj.com)

Embryonic stem cells come from human embryos that are three to five days old. (healthline.com)
Embryonic stem cells are known as pluripotent stem cells. (healthline.com)
Adult stem cells can't differentiate into as many other types of cells as embryonic stem cells can. (healthline.com)
To create iPSCs, scientists genetically reprogram the adult stem cells so they behave like embryonic stem cells. (healthline.com)
However, in recent years, there has been controversy surrounding the way human embryonic stem cells are obtained. (healthline.com)
Embryonic stem cells, which must be extracted from embryos three to five days old (known as blastocysts, which contain only about 150 cells at this point of development). (articlecity.com)
Adult stem cells, which are present in small amounts in adult tissue but less adaptable than embryonic stem cells, making their use in medical treatments more challenging. (articlecity.com)
They have many of the positive characteristics of embryonic stem cells while sourcing material is far less challenging, since postpartum tissue can be used. (articlecity.com)
Highly expressed in embryonic stem cells (ESCs). (joplink.net)
Embryonic stem cells are intriguing because they can differentiate into any of the specialized tissue cells of the body. (latimes.com)
Gene therapy and monoclonal antibodies didn't arrive with even a fraction of the hype surrounding embryonic stem cell research. (latimes.com)
4 5 Adipose tissue is an active endocrine organ, heterogeneous with respect to embryonic origin, body distribution and function. (bmj.com)
In 2009 beginning of 2010 we have focused on investigating what factors human embryonic stem cells (hESCs) may produce that enhance regeneration and if those factors have any effects by themselves on regeneration. (ca.gov)
Our work is at the stage of understanding the molecular mechanisms by which the aging of the regenerative potential of organ stem cells can be reversed by particular human embryonic factors that are capable of neutralizing the affects of aged niches on tissue regenerative capacity. (ca.gov)
Unlike earlier transcriptomics analyses using single-cell technologies, we observe that cells derived from human embryonic stem cells (hESCs) in the grafts adopt mature dopaminergic signatures. (lu.se)

Sites of loosely packed extracellular matrix (ECM) also offer stem and progenitor cell optimal space to proliferate and differentiate. (europa.eu)
Macrophages that differentiate from monocytes in the adult bone marrow are distinguished from tissue resident macrophages (e.g., alveolar macrophages, glial cells) that originally derive from fetal yolk sac progenitor cells or monocytes from the fetal liver ( Hoeffel and Ginhoux, 2018 ). (frontiersin.org)
MoDCs are also distinct in origin from conventional dendritic cells (cDCs) and plasmacytoid dendritic cells (pDCs) that are derived from a common dendritic cell progenitor (CDP). (frontiersin.org)
Monocytes can develop from either a granulocyte-monocyte progenitor (GMP) or a monocyte-dendritic cell progenitor (MDP). (frontiersin.org)
Common myeloid progenitor (CMP), granulocyte progenitor (GP), monocyte-committed progenitor (MP), common monocyte progenitor (cMoP), common dendritic cell progenitor (CDP), conventional dendritic cell (cDC), plasmacytoid dendritic cell (pDC). (frontiersin.org)
this released a flood of progenitor cells, or cells which eventually create new cartilage. (forbes.com)
Likewise, these cells give rise to progenitor cells committed to a particular cell lineage, and play a crucial role in tissue repair and homeostasis. (bvsalud.org)

Normal proliferative tissues contain multipotent stem cells (SCs) that drive tissue turnover. (medscape.com)

A particular stem cell type in the adult human-being is the 'Mesenchymal stem cell' (MSC). (europa.eu)
Mesenchymal stem cells (MSCs) from bone marrow play a critical role in osteochondral repair. (hindawi.com)
Mesenchymal stem cells (MSCs) play a key role in articular cartilage repair. (hindawi.com)
Induced EndoMT cells exhibited up-regulation of mesenchymal markers, including collagen type I and α-smooth muscle actin, and a reduction in endothelial cell and junctional proteins, including von Willebrand factor, CD31, occludin, and vascular endothelial-cadherin. (surrey.ac.uk)
Adipose tissue (AT) represents a commonly used source of mesenchymal stem/stromal cells (MSCs) whose proregenerative potential has been widely investigated in multiple clinical trials worldwide. (mdpi.com)
Human mesenchymal stem cells (hMSCs) have emerged as a leading candidate in cellular therapies due to their unique properties. (selectscience.net)
Seeding of bone implants with mesenchymal stem cells (MSCs) may promote osseointegration and bone regeneration. (nih.gov)
This innovative study by first-author Dr. Ani Grigoryan involved engineering mesenchymal stem cells and guiding them through a process mimicking how bones develop naturally in the human body. (lu.se)

We offer a broad portfolio of solutions for 3D cell culture including products for supporting spheroid growth, scaffolds, hydrogels, organoids, ULA plates, and other cultureware. (sigmaaldrich.com)
Cells grown on structural scaffolds engineered to mimic the ECM can be powerful, predictive models of physiological processes. (sigmaaldrich.com)
Our wide range of advanced 3D cell culture scaffolds includes nanofiber, collagen, polystyrene, and polycaprolactone materials. (sigmaaldrich.com)
Therefore, many laboratories try with great effort to develop resorbable tissue scaffolds that could support the patient´s cells. (nature.com)
Moreover, when exposed to serum-containing osteogenic medium, MSCs survived and differentiated on the peptide-coated scaffolds. (nih.gov)

Organoids are in vitro models that closely replicate the complex physiology of native tissues while also being accessible, reproducible, and scalable like traditional culture methods. (sigmaaldrich.com)
We realized that there was a big market in pharmaceutical companies for in vitro tissue models. (tecan.com)

In addition, natural extracellular matrix may allow for the study of tissue-specific biochemical, biophysical, and mechanical properties. (ntnu.no)
[2] [3] These adherent cells become embedded within a slimy extracellular matrix that is composed of extracellular polymeric substances (EPSs). (wikipedia.org)

There, MSC differentiate and regenerate tissue integrity. (europa.eu)
So one is to activate stem cells and the second is to regenerate tissue. (chiroeco.com)

The structure is essential because native ECM creates space where the cells are anchored, communicate, proliferate, differentiate, and die. (nature.com)

Precursor cells migrate to the thymus and differentiate into lymphocytes. (medscape.com)
Mobilized pluripotent MSCs from the subchondral bone migrate into the defect filled with the clot, differentiate into chondrocytes and osteoblasts, and form a repair tissue over time. (hindawi.com)
A new study in mice shows that these melanocyte stem cells migrate between two sites in the hair follicle during each cycle of hair growth and shedding- from a site where they produce the pigment for hair color to another where they produce stem cells. (medicalnewstoday.com)
Instead, a recent study published in Nature suggests that the McSCs can migrate back and forth between the two aforementioned locations, differentiating to produce hair pigment-producing melanocytes in the hair germ area and then translocating to the bulge and dedifferentiating to ensure the maintenance of an adequate supply of stem cells. (medicalnewstoday.com)

This special type of stem cell is present in many tissues and restores bone, connective tissues and fat. (europa.eu)
Prior to joining Surrey, her research centred around pulmonary hypertension and connective tissue diseases. (surrey.ac.uk)
However, persistent inflammation prevents proper tissue regeneration and instead results in fibrosis, the accumulation of connective tissue. (forbes.com)

For example, hematopoietic stem cells are a type of adult stem cell found in bone marrow. (healthline.com)
Doctors have been performing stem cell transplants, also known as bone marrow transplants, for decades using hematopoietic stem cells in order to treat certain types of cancer. (healthline.com)
For example, because hematopoietic stem cells can reconstitute the entire blood system, bone marrow transplantation has long been used in the clinic to treat various diseases. (articlecity.com)
All of these fungi can cause invasive disease in a wide-spectrum of immunocompromised patients, such as those with genetic immunodeficiencies, HIV/AIDS, cancer, solid organ, and hematopoietic stem cell transplantation, autoimmune diseases, immunosuppressive treatments, and other predisposing states like diabetes and pregnancy. (frontiersin.org)
Osteoclasts are bone resorbing, multinucleate cells that differentiate from mononuclear macrophage/monocyte-lineage hematopoietic precursor cells. (jci.org)
Hematopoietic stem cell (HSC) transplantation provides an effective platform for the treatment of hematological disorders. (rsc.org)

In the bone marrow MSC share the niche with haematopoietic stem cells (HSC). (europa.eu)
The additional application of a bone marrow aspirate (BMA) to the procedure of marrow stimulation is thought to enhance cartilage repair as it may provide both an additional cell population capable of chondrogenesis and a source of growth factors stimulating cartilage repair. (hindawi.com)
In the orthopaedic field, additional application of a bone marrow aspirate (BMA) to the procedure of marrow stimulation has been recently studied, since the bone marrow itself is both a source of MSCs, providing a cell population capable of chondrogenesis and of various growth factors stimulating cartilage repair [ 7 - 10 ]. (hindawi.com)
A focus is on the steps of mobilization of cells from the subchondral bone and repair tissue formation, including adherence of the bone marrow clot to the subchondral bone. (hindawi.com)

Our scientists pursue every aspect of cancer research-from exploring the biology of genes and cells, to developing immune-based treatments, uncovering the causes of metastasis, and more. (mskcc.org)
Likewise, the knowledge of stem cell biology is crucial to the development of stem cell therapies, based on tissue engineering applied to dentistry, seeking the regeneration of dental tissues damaged or lost by caries, trauma or genetic diseases. (bvsalud.org)
However, further studies are required to gain complete understanding of stem cell biology, which is fundamental for the development of successful cell-based therapies 1-3 . (bvsalud.org)
Each year, the Lund Stem Cell Center recognizes notable scientific achievements made by our members in the fields of stem cell biology and regenerative medicine through our Article of the Year Award. (lu.se)
This recognition highlights the outstanding contributions made by our members in advancing the fields of stem cell biology and regenerative medicine. (lu.se)

The stages that an organism undergoes from single cell to adult are many, complicated, and in constant danger of failure. (encyclopedia.com)
They are able to differentiate into any cell of an organism and have the ability of self-renewal. (articlecity.com)
Although functional organ stem cells persist in the old, tissue damage invariably overwhelms tissue repair, ultimately causing the demise of an organism. (ca.gov)
The microbial cells growing in a biofilm are physiologically distinct from planktonic cells of the same organism, which, by contrast, are single cells that may float or swim in a liquid medium. (wikipedia.org)

Cell Transplant;29: 963689720954798, 2020. (bvsalud.org)

In this talk Prof. Yeomans will answer this question and discuss the processes involved in wound healing and cell motility. (conference-service.com)
Within this mature population, we observed cells with distinct motility behaviors and function, with the relative proportion of static - bone resorptive (R) to moving - nonresorptive (N) varying in accordance with the pathophysiological conditions of the bone. (jci.org)
Subpopulations of cells within the biofilm differentiate to perform various activities for motility, matrix production, and sporulation, supporting the overall success of the biofilm. (wikipedia.org)

Monocytes and their derivatives, including macrophages and dendritic cells, play diverse roles in the response to fungal pathogens. (frontiersin.org)

The Fragility of Cryopreserved Insulin-producing Cells Differentiated from Adipose-tissue-derived Stem Cells. (bvsalud.org)
The aim of our study is to determine whether insulin -producing cells (IPCs) differentiated from adipose- tissue -derived stem cells (ADSCs) can be cryopreserved. (bvsalud.org)
Objectives (1) To compare spontaneous and stimuli-induced adipocytokine secretion by articular adipose tissue (AAT) and synovial membrane (SM) explants obtained from patients with rheumatoid arthritis (RA). (bmj.com)
Recently, adipose tissue has been shown to synthesise and release highly bioactive substances: classical adipokines (eg, leptin, adiponectin) and various proinflammatory factors such as cytokines, chemokines, growth factors and complement components. (bmj.com)
Here we demonstrate that a branched poly[Lys(Ser(i)-DL-Ala(m))] polymer functionalized with cyclic arginyl-glycyl-aspartate, when immobilized by simple adsorption to tissue culture plastic, surgical titanium alloy (Ti6Al4V), or Bio-Oss(®) bovine bone substitute, significantly accelerates serum-free adhesion and enhances seeding efficiency of human adipose tissue-derived MSCs. (nih.gov)

Similarly, the transplantation of other tissue-specific stem cells, such as stem cells isolated from epithelial and neural tissues, can treat mouse disease models and human patients in which epithelial and neural cells are damaged. (articlecity.com)
One way is to carry out the transplantation, but the success of this strategy is complicated by immune reactions to allogeneic or xenogeneic grafts or deficiency of donor tissue. (nature.com)

Also in contrast to the bifacial cambium, the unifacial cambium is unable to expand its circumference with anticlinal cell division. (wikipedia.org)
In contrast to the cost- and labor-intensive cultivation and propagation of cells such as MSCs or articular chondrocytes, the clinical use of "minimally processed" autologous BMA that can be prepared in the operation room as a single-step procedure appears straightforward. (hindawi.com)
By contrast, transit amplifying cells and differentiated cells are incapable of self-renewal and tissue regeneration. (medscape.com)

With this raw material, biomedical firms can create stem cell lines that, among other things, aid recuperation via the regeneration of tissue that has been lost or damaged. (articlecity.com)
Stem cells in the body are responsible for the regeneration of tissue in the body and can differentiate to form an array of specialized cells. (medicalnewstoday.com)

Thymoma originates within the epithelial cells of the thymus, a lymphoid organ located in the anterior mediastinum. (medscape.com)
In early life, the thymus is responsible for the development and maturation of cell-mediated immunologic functions. (medscape.com)
The thymus is composed predominantly of epithelial cells and lymphocytes. (medscape.com)

Once altered by tafazzin, cardiolipin is key in maintaining mitochondrial shape, energy production, and protein transport within cells. (medlineplus.gov)

When your vet tests the cells within the lump or lesion, she'll be able to tell you whether an MCT is benign or malignant. (dogsnaturallymagazine.com)

1 In RA, numerous cytokines play a fundamental role in inflammation and joint destruction and are thought to originate primarily from synoviocytes and leucocytes that massively infiltrate synovial tissue. (bmj.com)
first collected synovial fluid from osteoarthritis patients, and then separated the cells from the fluid. (forbes.com)
Prominent immunologic abnormalities include immune complexes produced by synovial lining cells and in inflamed blood vessels. (merckmanuals.com)
Lymphocytes that infiltrate the synovial tissue are primarily CD4 + T cells. (merckmanuals.com)

They are very different from high-grade cancers and represent about 10% to 15% of epithelial ovarian/fallopian tube neoplasms, which are abnormal growths of cells. (cancer.net)
Alternately, abnormal growth may continue, leading to fibrovascular tissue in the vitreous cavity. (medscape.com)
Conversely, the cells appear abnormal in cancers that spread more aggressively - higher grade cancers. (medicalnewstoday.com)
Grading defines the type of mass and the characteristics of the abnormal cells. (dogsnaturallymagazine.com)
It tells you whether all abnormal cells were removed, and whether - or how fast - the cancerous mast cells may spread in the body. (dogsnaturallymagazine.com)

This piece will focus on the medical technology being developed using Wharton's jelly as a source material for stem cells, but will also delve into broader aspects of stem cell research, one of the most fascinating current areas of scientific study. (articlecity.com)
So when St. Francis Memorial Hospital in San Francisco announced that the topic of his speech there last week would be "Stem Cell Research: Hope or Hype? (latimes.com)
Skepticism about the potential of stem cell research was wholly absent from the campaign for Proposition 71. (latimes.com)
Among this years winners are studies that represent some of the ways in which we perceive and engage with stem cell research are being reshaped. (lu.se)

Found within Wharton's jelly - which is easily harvested from what would otherwise be post-natal medical waste - are several distinct stem cell genes. (articlecity.com)

ECM provides mechanical support for cells and also determines the shape of tissue 9 . (nature.com)

This failed tissue regeneration is key to osteoarthritis. (forbes.com)

Specifically, the division of a stem cell can result in the formation of identical daughter stem cells and/or cells that can differentiate to assume different fates. (medicalnewstoday.com)
We propose that racial residential segregation and discrimination increases tissue inflammation and cytokine production, resulting in dysregulated immune signaling, which promotes plaque formation and cardiovascular disease. (frontiersin.org)
Two morphological types of cell death were found: apoptosis which was characterized by round or semilunar nuclear chromatin condensations, condensation and shrinkage of the cytoplasm and formation of apoptotic bodies, and cell death without the morphological features of apoptosis which was characterized by pyknotic nuclear chromatin condensations, vacuolated cytoplasm and the formation of numerous intercellular spaces. (karger.com)

There was an excess occurrence of non-Hodgkin lymphoma and soft-tissue sarcoma but of no other specific cancers. (medscape.com)
Prompted by earlier reports indicative of a strong association between the occurrence of soft tissue sarcoma and exposure to dioxins, the death certificates and pathology records of seven chemical workers affected by soft tissue sarcoma were reviewed. (cdc.gov)
The authors conclude that death certificates and pathology records are not reliable sources for the identification of cases of soft tissue sarcoma and recommend large scale studies to determine the validity of the association between exposure to dioxins and the occurrence of the neoplasm. (cdc.gov)
Ultrasonography is non-radiographic and noninvasive, using high-frequency sound waves to view deep soft-tissue structures. (oncolink.org)

Aggregate of microorganisms in which cells that are frequently embedded within a self-produced matrix of extracellular polymeric substances (EPSs) adhere to each other and/or to a surface. (wikipedia.org)
A biofilm comprises any syntrophic consortium of microorganisms in which cells stick to each other and often also to a surface. (wikipedia.org)
a germicide that is used on skin or living tissue for the purpose of inhibiting or destroying microorganisms. (cdc.gov)

A major component outside of the cells, which notably is distinctly involved in controlling and guiding many cellular processes, is the polysaccharide hyaluronan (HA). (europa.eu)
Induced pluripotent stem cells, which harness the power of genetic reprogramming - basically, the altering of a cell's DNA - to change the course of cellular development. (articlecity.com)
The increased resistance observed for the non-endothelial cell types was accompanied by an increased rate of cellular attachment, even though spontaneous migration was comparable to the control, i.e., to the standard cultivation surface. (nature.com)
Microbes form a biofilm in response to a number of different factors, [9] which may include cellular recognition of specific or non-specific attachment sites on a surface, nutritional cues, or in some cases, by exposure of planktonic cells to sub-inhibitory concentrations of antibiotics . (wikipedia.org)
According to the cancer stem cell (CSC) concept, the cellular hierarchy in normal tissues is preserved in a number of hematological and solid malignancies. (medscape.com)

Adult stem cells have a misleading name, because they are also found in infants and children. (healthline.com)
Scientists have recently discovered how to turn adult stem cells into pluripotent stem cells. (healthline.com)
Adult stem cells don't present any ethical problems. (healthline.com)
It will allow us, as researchers, to not live in the lab and control our tissue culture conditions, including the sensitive cultures including those like adult stem cells. (al.com)

Current research is focused on growing a wide range of new tissue from stem cells, including muscle, blood, brain, and cartilage cells. (articlecity.com)

Pathological evidence for residual SARS-CoV-2 in pulmonary tissues of a ready-for-discharge patient. (cdc.gov)
Pulmonary arterial hypertension (PAH) is a progressive disease characterized by lung endothelial cell dysfunction and vascular remodeling. (surrey.ac.uk)

These new types of cells are called induced pluripotent stem cells (iPSCs). (healthline.com)

To circumvent these obstacles, we have developed two methods for the investigation of human neural cells in culture. (lu.se)

surrounding somatic cells flatten the 16-cell differentiating cyst, resulting in an increase of the membrane tension of germ cells inside the cyst. (glasp.co)
Before the announcement in February 1997 of the cloning of a sheep by somatic cell nuclear transfer, existing legislation in a number of countries already precluded human cloning for reproductive purposes, sometimes implicitly. (who.int)

the other as differential, or differentiating division. (dictionary.com)
[ 7 ] Knowledge of preceding treatment and the finding of other therapy-related changes, such as glandular atrophy, as well as basal cell hyperplasia, should alert to this differential. (medscape.com)

increased macrophage-derived lining cells are prominent along with vessel inflammation. (merckmanuals.com)
Here, we review these societal and structural factors and then link them with biological processes such as telomere shortening, allostatic load, oxidative stress, and tissue inflammation. (frontiersin.org)

Ident- cult to deduce interaction rules from observations of the ified transcription factors for specific cell fates are, for entire system. (lu.se)

If prostate biopsies are performed following hormonal therapy for prostatic adenocarcinoma, the appearance of residual tumor cells can mimic xanthoma cells. (medscape.com)

Individuals have been studied from well-defined population groups in which colonic epithelial cells have progressed to increasingly advanced stages of neoplastic transformation. (elsevierpure.com)

For many years there is an urgent need in the field of regenerative medicine to develop replacements of non-functional tissues. (nature.com)

[ 4 ] This is especially the case when they occur in seemingly infiltrating nests, cords, or single cells on small biopsy specimens. (medscape.com)
Plasma cells produce antibodies (eg, rheumatoid factor [RF], anticyclic citrullinated peptide [anti-CCP] antibody) that contribute to these complexes, but destructive arthritis can occur in their absence. (merckmanuals.com)

Plays a key role in increased proteasome activity in bryonic st cells (ESCs): its high expression in ESCs promotes enhanced assbly of the 26S proteasome, followed by higher proteasome activity. (joplink.net)
Expression decreases as ESCs differentiate. (joplink.net)
METHODS: Fifty-three paraffin-embedded tissue blocks of colorectal resections and corresponding patient information were retrieved from the archives of the Anatomic and Molecular Pathology Department of Lagos University Teaching Hospital.A 4-micron slide section was obtained from each specimen and immunohistochemistry for COX-2 and HER-2 expression was performed. (bvsalud.org)

Osteocyte-like cells were identified as entrapped, stellate-shaped cells interconnected through canaliculi embedded in a structured, mineralized, collagen matrix. (ntnu.no)
Organized collagen fibrils, observed associated with the cell hydroxyapatite (HAp) crystals, were found throughout the spheroid and in between the collagen fibrils. (ntnu.no)
Animals are generally considered to be multicellular organisms that are capable of locomotion in response to their environment (motile), are required to ingest or eat and swallow other organisms to gain proper nutrition (heterotropic), contain within each cell genetic material organized as two sets of chromosomes within a membrane-bound nucleus ( eukaryotic ), develop through a blastula (hollow ball) stage, and integrate muscle tissue, nervous tissue, and collagen into their body. (newworldencyclopedia.org)

[ 8 ] and can resemble xanthoma cells in small biopsies. (medscape.com)
Cells embedded in 3D hydrogels can polarize, differentiate and have functional attributes that more closely resemble physiological tissues. (sigmaaldrich.com)

Cell death in the axial structures, i.e. spinal cord, notochord and surrounding mesenchyme and somites, was analyzed using light and electron microscopy. (karger.com)

We have established cell culture conditions that favored the natural 3D orientation of the bone cells and stimulated the cascade of signaling needed for primary human osteoblasts to differentiate into osteocytes with the characteristically phenotypical dendritic network between cells. (ntnu.no)

This type of stem cell is very versatile and has a wide range of uses, though procuring them entails medical and ethical challenges. (articlecity.com)

All humans start out as only one cell. (healthline.com)
Furthermore, we have used this protocol to differentiate PSCs from humans and chimpanzees. (lu.se)

Foamy gland carcinoma of the prostate features cells with abundant finely vacuolated cytoplasm and pyknotic hyperchromatic nuclei. (medscape.com)
Animals are eukaryotic (genetic material is organized in membrane-bound nuclei) and multicellular (comprised of more than one cell), which separates them from bacteria and most protists . (newworldencyclopedia.org)

Cells naturally grow and differentiate in 3D environments. (sigmaaldrich.com)
A light and electron microscopic study of naturally occurring and induced cell loss during development. (karger.com)

Anatomy25

Organisms4

Diseases4

Chemicals and Drugs11

Analytical, Diagnostic and Therapeutic Techniques and Equipment17

Phenomena and Processes17

Disciplines and Occupations2

Information Science3

Differentiation15

Poorly differentiated3

Tumors8

Organs7

Fully differentiated2

Further differentiate3

Endothelial cells7

Embryonic15

Progenitor7

Multipotent stem1

Mesenchymal8

Scaffolds5

Vitro2

Extracellular matrix2

Regenerate tissue2

Proliferate1

Migrate4

Connective3

Hematopoietic6

Bone marrow4

Biology5

Organism4

20201

Motility3

Macrophages1

Adipose tissue5

Transplantation2

Contrast3

Regeneration of tissue2

Thymus3

Mitochondrial1

Malignant1

Synovial4

Abnormal5

Stem Cell Res4

Post-natal1

Mechanical1

Failed tissue regeneration1

Formation3

Soft tissue4

Microorganisms3

Cellular5

Adult stem4

Cartilage cells1

Pulmonary2

Pluripotent stem1

Neural cells1

Somatic2

Differential2

Inflammation2

Fates1

Adenocarcinoma1

Epithelial cells1

Regenerative medicine1

Occur2

Expression3

Collagen3

Resemble2

Electron microscopy1

Dendritic1

Type of stem cell1

Humans2

Nuclei2

Naturally2