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  • donors
  • A French multicenter survey of end-of-life practices in ICU may help to identify potential appropriate organ donors and to interpret nation-specific considerations of the related professional, legal, and ethical frameworks. (springeropen.com)
  • The probe was first reported by the New York Daily News in October 2005, and led to a number of exhumations, including one of a Queens, New York, woman who had had many of her bones removed and replaced with PVC piping, which is a typical industry practice for cosmetic reconstruction of tissue donors. (wikipedia.org)
  • Under federal regulatory guidelines for the proper care and management of donated human tissue, firms are required to "screen and test donors for relevant communicable disease agents and diseases and to ensure that HCT/Ps are processed in a way that prevents communicable disease contamination and cross-contamination. (wikipedia.org)
  • In the United States, there are a total of 58 Organ Procurement Organizations (OPOs) that are responsible for evaluating the candidacy of deceased donors for organ donation as well as coordinating the procurement of the organs. (wikipedia.org)
  • DCD had been the norm for organ donors until 'brain death' became a legal definition in the United States in 1981. (wikipedia.org)
  • In the United States, the match between human donors and recipients is coordinated by groups like United Network for Organ Sharing. (wikipedia.org)
  • after this and several subsequent unsuccessful attempts to use primates as organ donors and the development of a working cadaver organ procuring program, interest in xenotransplantation for kidney failure dissipated. (wikipedia.org)
  • These coordinators can act as link between hospitals, citizens, donors and patients requiring organ donation. (wikipedia.org)
  • fetal
  • Where is the psychological reaction to Planned Parenthood's dispersal of fetal tissue for scientific research coming from? (decodedscience.org)
  • You may have seen a video, released online, that showed a doctor from Planned Parenthood talking with actors, posing as buyers from a fetal tissue procurement company, about the pricing and use of fetal organs for scientific research. (decodedscience.org)
  • This video has sparked a huge uproar and debate between the pro-choice and pro-life communities, and has generated many questions about the legality and appropriateness of the use of fetal tissues. (decodedscience.org)
  • This fear and disgust can then affect support for any research that deals with the use of aborted fetal tissue. (decodedscience.org)
  • WASHINGTON - A special House committee empaneled to investigate fetal tissue research is preparing to issue 17 subpoenas to medical supply companies and laboratories, seeking the names of researchers, graduate students, laboratory technicians and administrative personnel. (allgov.com)
  • The House investigation into how some of the nation's most prestigious universities acquire fetal tissue has prompted charges of intimidation and coercion, escalating a battle that some researchers fear could shut down studies seeking cures for Parkinson's disease, the Zika virus and a host of other conditions. (allgov.com)
  • who opposes most fetal tissue research because of its association with abortion, intends to issue the subpoenas on behalf of the Republicans on the House Select Investigative Panel on Infant Lives. (allgov.com)
  • The panel was created to investigate fetal tissue research after the release of surreptitiously recorded videos purporting to show Planned Parenthood officials trying to profit illegally from the sale of such tissue. (allgov.com)
  • University officials fear that the release of the names sought by lawmakers could endanger lives if anti-abortion activists decide to target those involved in fetal tissue research. (allgov.com)
  • Some medical studies have been delayed or canceled because researchers can no longer acquire fetal tissue samples from their usual suppliers, who have grown concerned about the investigation, researchers said. (allgov.com)
  • Colorado State University suspended its acquisition of fetal tissue from "vendors implicated in the Planned Parenthood investigation pending the outcome of the congressional inquiry," the university said in a letter to Congress in July. (allgov.com)
  • Brigham and Women's Hospital in Boston, a teaching hospital for Harvard Medical School, no longer accepts applications from researchers seeking fetal tissue from abortions performed there. (allgov.com)
  • This act is a response to the idea that, at some point in the future, a technology might be developed that involved cells or tissues being removed from fetuses and used for fetal tissue implants or stem cell therapy. (wikipedia.org)
  • In the Act, this procedure was defined as the intentional creation and use of human fetal tissues or organs for scientific or medical purposes. (wikipedia.org)
  • October 10, 1998 Robert P. George, "Stem Cells Without Moral Corruption", Washington Post, July 6, 2006 Wesley J. Smith, Fetal Farming Pushed at Huffington Post Jacob M. Appel, Are We Ready for a Market in Fetal Organs, Huffington Post. (wikipedia.org)
  • graft
  • OBJECTIVES: Our objective was to evaluate the impact of vein graft harvesting technique on structure and function of vasa vasorum. (biomedsearch.com)
  • Video footage of superficial vasa vasorum in an implanted saphenous vein graft harvested with the no-touch technique was captured during a coronary bypass operation and is presented for online viewing. (biomedsearch.com)
  • Video footage showed retrograde flow in the vasa vasorum in vein graft harvested with the no-touch technique. (biomedsearch.com)
  • CONCLUSIONS: These findings show that the no-touch technique for saphenous vein graft harvesting for coronary bypass grafting preserves an intact vasa vasorum. (biomedsearch.com)
  • While Endoscopic Vein Harvest (EVH) has been demonstrated to improve early morbidity compared to Open Vein Harvest (OVH), recent literature suggests that this may be at the expense of graft patency at one year and survival at three years. (biomedsearch.com)
  • The theoretical organ donor eligibility (for kidney, liver, or lung retrieval) of deceased patients was determined a posteriori 1) according to routine medical criteria for graft selection and 2) according to the WoWt measures implemented and their impact on organ viability. (springeropen.com)
  • On September 4, 2008, defense attorneys for human graft tissue distributors asked U.S. District Judge William J. Martini to dismiss hundreds of charges, asserting that the companies "never knew the body parts were illegally obtained, and they say there is no evidence the transplanted tissue made anyone ill. (wikipedia.org)
  • According to the FDA, all tissue products collected and distributed by BTS were recalled and will be monitored for a complete accounting of all graft material. (wikipedia.org)
  • Overall, about 10,000 patients in the United States and Canada received graft tissue from BTS. (wikipedia.org)
  • transplants
  • In the United States, prisoners are not discriminated against as organ recipients and are equally eligible for organ transplants along with the general population. (wikipedia.org)
  • If a prisoner qualifies, a state may allow compassionate early release to avoid high costs associated with organ transplants. (wikipedia.org)
  • Advocates support development of therapeutic cloning in order to generate tissues and whole organs to treat patients who otherwise cannot obtain transplants, to avoid the need for immunosuppressive drugs, and to stave off the effects of aging. (wikipedia.org)
  • In December 2005, China's Deputy Health Minister acknowledged that the practice of removing organs from executed prisoners for transplants was widespread. (wikipedia.org)
  • The condemned prisoners have been described as "not a proper source for organ transplants" by Vice-Health Minister Huang Jiefu, and in March 2010 he announced the trial of China's first organ donation program starting after death, jointly run by the Red Cross Society and the Ministry of Health, in 10 pilot regions. (wikipedia.org)
  • plant tissues
  • The pathogen can survive as mycelium for a few days in dead and dying plant tissues as well as in infected corms. (wikipedia.org)
  • As they gorge on intracellular fluid, the bacteria continue to multiply and move into the intercellular spaces, with their cell-wall-degrading enzymes ahead of them preparing the plant tissues for digestion. (wikipedia.org)
  • The bacteria then overwinters within the plant tissues, insect hosts, or in the soil and lay dormant until the conditions are right again to reproduce. (wikipedia.org)
  • grafts
  • The 'no-touch' harvesting technique for vein grafts in coronary artery bypass surgery preserves an intact vasa vasorum. (biomedsearch.com)
  • RESULTS: The total area of vasa vasorum in vein grafts harvested with the conventional technique was significantly reduced both in the media (P = .007) and in the adventitia (P = .014) compared with vein grafts harvested with the no-touch technique. (biomedsearch.com)
  • Cardiopulmonary support was withdrawn in only five of these patients, and three died within 120 minutes after withdrawal (the maximum delay compatible with organ viability for donor grafts). (springeropen.com)
  • Humans
  • Opponents of cloning have concerns that technology is not yet developed enough to be safe, that it could be prone to abuse (leading to the generation of humans from whom organs and tissues would be harvested), and have concerns about how cloned individuals could integrate with families and with society at large. (wikipedia.org)
  • A continuing concern is that many animals, such as pigs, have a shorter lifespan than humans, meaning that their tissues age at a quicker rate. (wikipedia.org)
  • human
  • The US tissue industry generates total revenues of about $1 billion a year, says journalist Martina Keller, a co-author of this article and the author of the German book, "Cannibalized: The Human Corpse as a Resource. (blogspot.com)
  • She is a co-founder of Organs Watch, an independent, medical human rights, research and documentation center at UC Berkeley. (thetruthseeker.co.uk)
  • Federal law forbids profiting from the sale of human organs or tissue. (allgov.com)
  • In nearly every case, BTS employees obtained human allograft tissue, bones, ligaments and other cadaver material by forging family consent and other donor forms without actual authorized consent, and often against the written wishes of families. (wikipedia.org)
  • Human xenotransplantation offers a potential treatment for end-stage organ failure, a significant health problem in parts of the industrialized world. (wikipedia.org)
  • Human organs have been transplanted into animals as a powerful research technique for studying human biology without harming human patients. (wikipedia.org)
  • The animal organ, probably from a pig or baboon could be genetically altered with human genes to trick a patient's immune system into accepting it as a part of its own body. (wikipedia.org)
  • The term is generally used to refer to artificial human cloning, which is the reproduction of human cells and tissue. (wikipedia.org)
  • Reproductive cloning would involve making an entire cloned human, instead of just specific cells or tissues. (wikipedia.org)
  • In 2004 and 2005, Hwang Woo-suk, a professor at Seoul National University, published two separate articles in the journal Science claiming to have successfully harvested pluripotent, embryonic stem cells from a cloned human blastocyst using somatic-cell nuclear transfer techniques. (wikipedia.org)
  • There are 23 organs in the human body and one can donate kidney, heart, liver, lungs, pancreas and the small bowel as well as tissues like cornea, skin, bone, tendons, cartilage and heart valves. (wikipedia.org)
  • recipients
  • A limited number of opinion polls have indicated broad favor for the practice within both the general public and organ recipients. (wikipedia.org)
  • allegations
  • Long before Donald Boström leveled allegations of organ-harvesting from Palestinians in the Swedish tabloid, Aftonbladet, in August 2009, causing furious accusations of "blood libel," Dr. Scheper-Hughes had already interviewed Dr. Hiss and had on tape the interview that forms part of her report here. (thetruthseeker.co.uk)
  • kidney
  • Organ donation, however, has met resistance, and involuntary organ donation is illegal under Chinese law, as it is against Chinese tradition and culture, which attach symbolic life affirming importance to the kidney and heart. (wikipedia.org)
  • allocation
  • In 2013, Huang Jiefu altered his position on utilizing prisoners' organs, stating that death row prisoners should be allowed to donate organs and should be integrated into the new computer-based organ allocation system. (wikipedia.org)
  • stem
  • Bioethics Organ trade Unborn Victims of Violence Act Washington Post: Stem Cell Bill Gets Bush's First Veto. (wikipedia.org)
  • In Aubrey de Grey's proposed SENS (Strategies for Engineered Negligible Senescence), one of the considered options to repair the cell depletion related to cellular senescence is to grow replacement tissues from stem cells harvested from a cloned embryo. (wikipedia.org)
  • cells
  • During the immune response to influenza infection, activated T cells are distributed to both lymphoid and extralymphoid tissues, including the infected airways where direct recognition of viral Ag-bearing cells takes place. (jimmunol.org)
  • The proportion of CD4 + cells expressing CD49a (α 1 integrin) was low in all tissues sampled during primary infection but increased in the airways after viral clearance. (jimmunol.org)
  • Airway CD49a + CD4 + cells also expressed reduced markers of apoptosis compared with CD49a − cells, and fewer memory or effector CD4 + cells could be recovered from airways of α 1 −/− mice, although lymphoid tissues appeared unaffected. (jimmunol.org)
  • These data suggest VLA-1 expression defines a population of tissue memory CD4 + T cells that act as rapid effectors upon reinfection, and VLA-1 expression is integral to their accumulation in the airways. (jimmunol.org)
  • More recent data suggest that memory T cells residing in extralymphoid tissues such as the lung seem especially capable of aiding in protection against serologically distinct flu variants in mice ( 4 - 7 ). (jimmunol.org)
  • Although there is obvious benefit to the host in retaining populations of memory CD4 + cells in both the lymphoid tissues and extralymphoid tissues such as the lung, little is known about the signals that select or retain memory cells in the extralymphoid compartment. (jimmunol.org)
  • Previous work has shown that the α 1 β 1 integrin VLA-1 (detected by staining with Ab to the α 1 integrin chain/CD49a) is expressed on primed CD8 + T cells in the lung and other extralymphoid tissues, and its interaction with type IV collagen may be important for CD8 + cell residence in the airways ( 18 ). (jimmunol.org)
  • Such cells, tissues, and organs would neither trigger an immune response nor require the use of immunosuppressive drugs. (wikipedia.org)
  • Such cells, tissues or organs are called xenografts or xenotransplants. (wikipedia.org)
  • Certain procedures, some of which are being investigated in early clinical trials, aim to use cells or tissues from other species to treat life-threatening and debilitating illnesses such as cancer, diabetes, liver failure and Parkinson's disease. (wikipedia.org)
  • forbids
  • Although no law specifically forbids death row inmates from donating organs postmortem, as of 2013 all requests by death row inmates to donate their organs after execution have been denied by states. (wikipedia.org)
  • 1984
  • though, under a 1984 regulation, it became legal to remove organs from executed criminals with the prior consent of the criminal or permission of relatives. (wikipedia.org)
  • Reports of organs being removed from executed prisoners in China for sale internationally had been circulating since the mid-1980s, when a 1984 regulation made it legal to harvest organs from convicted criminals with the consent of the family or if the body goes unclaimed. (wikipedia.org)
  • pigs
  • Multiple-organ procurement models are also developed from slaughtered pigs to reduce the use of laboratory animals. (wikipedia.org)
  • In the first two decades of the 20th century, several subsequent efforts attempts to use organs from lambs, pigs and primates were published. (wikipedia.org)
  • illegally
  • Of the numerous companies who purchased the illegally obtained body parts, or tissue, none had ever contacted the family member listed on the deceased consent forms to verify the consent, or even that the consenting person listed actually existed. (wikipedia.org)
  • practitioners
  • Persisting shortfall in available organs prompted French authorities and practitioners to focus on organ retrieval in patients withdrawn from life-sustaining treatment and awaiting cardiac arrest (Maastricht classification category III). (springeropen.com)
  • METHODS
  • METHODS: We conducted a review of our initial 42 (19 with 6-month follow up) consecutive DSAEK surgeries using ASF tissue compared with 357 (199 with 6-month follow up) time-matched controls using standard tissue. (biomedsearch.com)
  • METHODS: Paired segments of great saphenous veins harvested either with conventional harvesting technique or no-touch technique were obtained from 9 consecutive patients undergoing coronary artery bypass grafting. (biomedsearch.com)
  • patients
  • CONCLUSIONS: While aware of the limitations of this small retrospective study, we are heartened by the preliminary results and consider our data to be justification for continuing to provide patients the opportunity to have minimally invasive conduit harvest in our centre. (biomedsearch.com)
  • Forty-four patients presented a contraindication ruling out organ retrieval either preexisting admission (n = 20) or emerged during hospitalization (n = 24). (springeropen.com)
  • citation needed] Although a recent judicial ruling has increased the difficulty of patients in proving pain and suffering from receiving bad donor tissue in cases like these, Pfaff's lawsuit is still pending. (wikipedia.org)
  • citation needed] Other patients who received BTS-derived tissue and body parts include a Colorado woman who had to repeat her ACL replacement surgery after her first BTS tendon failed, an Ohio woman who developed syphilis after receiving a bone from BTS, and an Ohio man who developed both HIV and hepatitis C after receiving BTS bone implants in surgery. (wikipedia.org)
  • Due to the lack of organ availability, about 20 patients die each day on the waiting list for organs. (wikipedia.org)
  • Donation after cardiac death (DCD) involves surgeons taking organs within minutes of the cessation of respirators and other forms of life support for patients who still have at least some brain activity. (wikipedia.org)
  • Organ donation has the potential to greatly improve quality of life as well as prevent death in patients with end-stage organ failure. (wikipedia.org)
  • Xenotransplants could save thousands of patients waiting for donated organs. (wikipedia.org)
  • The structured training ensures that they are able to approach and counsel the families of brain dead patients for organ donation. (wikipedia.org)
  • surgery
  • PURPOSE: The purpose of this study was to evaluate outcomes of Descemet's stripping automated endothelial keratoplasty (DSAEK) using anterior stromal flawed (ASF) donor corneas that were unsuitable for use in full-thickness penetrating keratoplasty as a result of stromal scars, pterygia, or previous corneal refractive surgery and to compare results with DSAEK using standard tissue. (biomedsearch.com)
  • RESULTS: One surgeon-cut ASF tissue was perforated before surgery and was discarded. (biomedsearch.com)
  • rejection
  • If consent is obtained from the potential donor or the potential donor's survivors, the next step is to perform a match between the source (donor) and the target (recipient) to reduce rejection of the organ by the recipient's immune system. (wikipedia.org)
  • Scientific interest in xenotransplantation declined when the immunological basis of the organ rejection process was described. (wikipedia.org)
  • prisoners
  • However, with modern testing advances to more safely rule out infectious disease and by ensuring that there are no incentives offered to participate, some have argued that prisoners can now voluntarily consent to organ donation just as they can now consent to medical procedures in general. (wikipedia.org)
  • With careful safeguards, and with over 2 million prisoners in the U.S., they reason that prisoners can provide a solution for reducing organ shortages in the U.S. While some have argued that prisoner participation would likely be too low to make a difference, one Arizona program started by Maricopa County Sheriff Joe Arpaio encourages inmates to voluntarily sign up to donate their heart and other organs. (wikipedia.org)
  • Despite these initiatives, China Daily reported in August 2009 that approximately 65% of transplanted organs still came from death row prisoners. (wikipedia.org)
  • Medical
  • But now Krat, a mother of two young girls, has learned from SPIEGEL that the Ukrainian company in question sends the body parts to a German company, Tutogen Medical GmbH, which in turn apparently supplies large numbers of such parts to the American tissue market. (blogspot.com)
  • A society with highly developed medical technology, the Vidiians harvest organs from corpses and living beings to stall the progression of the Phage, and experiment on other alien species in an attempt to develop a cure. (wikipedia.org)
  • They have developed advanced medical technology to remotely harvest organs directly from living humanoids in order to stop the progression of the Phage, which causes tissue to disintegrate on a cellular level. (wikipedia.org)
  • However, due to the lack of awareness level among the public and medical professionals, this concept of organ donation in India needed a shift in attitudes. (wikipedia.org)
  • species
  • They are represented as a nomadic species suffering from a pandemic known as the Phage, which destroys their tissue. (wikipedia.org)
  • After Captain Kathryn Janeway (Kate Mulgrew) pursues the Vidiians to recover Neelix's organs, the Vidiians explain that their entire species has been infected by a pandemic known as the Phage. (wikipedia.org)
  • immune
  • They have re-emerged because of the lack of organs available and the constant battle to keep immune systems from rejecting allotransplants. (wikipedia.org)
  • available
  • Shimazono, Y. "The State of the International Organ Trade: A Provisional Picture Based on Integration of Available Information. (wikipedia.org)
  • When a prisoner receives an organ, there is a high probability that someone else will die waiting for the next available organ. (wikipedia.org)
  • programmes
  • The foundation organises awareness talks among public through meetings, holds rallies, organises programmes in colleges and offices with organ donation as a theme, sensitises police and hospital staff on issues related to donation and from time to time honours organ donor families. (wikipedia.org)
  • infection
  • Decayed corm tissue appears brown and turns purplish in advanced stages of infection. (wikipedia.org)
  • Upon infection, oospores that overwinter on leaf tissue and petioles give rise to sporangiophores which have lemon-shaped sporangia at their tips. (wikipedia.org)