Tin protoporphyrin. Medical search. Frequent questions

An alternative name for heme is iron protoporphyrin IX (iron PPIX). (wikipedia.org)
Protoporphyrin IX reacts with iron salts in air to give the complex FeCl(PPIX). (wikipedia.org)
The time dependent inhomogeneous distribution of the photoactive compound protoporphyrin IX (PpIX) is calculated after obtaining its precursor distribution (Methyl aminolevulinate, MAL) which depends on the drug permeability, diffusion properties of the skin, incubation time and conversion efficiency of MAL to PpIX. (unican.es)

Other metals - nickel, tin, chromium - have been investigated for their therapeutic value. (wikipedia.org)
The in vitro antimalarial activity against Plasmodium falciparum and heine polymerization were evaluated for ten metalloporphyrins: gallium protoporphyrin IX (GaPPIX), sodium salt of gallium protoporphyrin IX, silver protoporphyrin IX, palladium protoporphyrin IX, cobalt protoporphyrin IX, manganese protoporphyrin IX, tin protoporphyrin IX (SnPPIX), chromium protoporphyrin IX, gallium deuteroporphyrin IX (GaDPIX) and gallium hematoporphyrin IX. (elsevierpure.com)

Protoporphyrin IX is an organic compound, classified as a porphyrin, that plays an important role in living organisms as a precursor to other critical compounds like heme (hemoglobin) and chlorophyll. (wikipedia.org)
Protoporphyrin IX is an important precursor to biologically essential prosthetic groups such as heme, cytochrome c, and chlorophylls. (wikipedia.org)
In the human body, lead inhibits porphobilinogen synthase and ferrochelatase, preventing both porphobilinogen formation and the incorporation of iron into protoporphyrin IX, the final step in heme synthesis. (cargohandbook.com)

This precursor is converted to protoporphyrinogen IX, which is oxidized to protoporphyrin IX. (wikipedia.org)

Erythrocyte total protoporphyrin is the initial screening exam to diagnose EPP and XLP, if the total is elevated with metal-free protoporphyrin it is suggestive of EPP or XLP. (medscape.com)
A total of 95 workers were screened using a zinc-protoporphyrin (ZPP) test. (cdc.gov)
The combined first and second ionization energies -the total energy required to remove the two 6p electrons-is close to that of tin , lead's upper neighbor in the carbon group . (wikiversity.org)

In vitro: cultured cardiomyocytes were treated with cobalt-protoporphyrin (CoPP) and tin protoporphyrin (SnPP) prior to hypoxic stress. (nih.gov)
In the RAW264.7 cells that were vitalized by Escherichia coli ( E. coli ) LPS, the β-glucan inhibited both the combatant and rendering phases of the inducible NO synthase (iNOS)-derived NO. β-Glucan increased the expression of the heme oxygenase-1 (HO-1) in the cells that were stimulated by E. coli LPS, and the HO-1 activation was inhibited by the tin protoporphyrin IX (SnPP). (animbiosci.org)

Such impairment of the NO-elicited cGMP increase was restored significantly by tin protoporphyrin IX, an HO inhibitor. (elsevierpure.com)

A total of 95 workers were screened using a zinc-protoporphyrin (ZPP) test. (cdc.gov)
19. Iron protoporphyrin IX (hemin) but not tin or zinc protoporphyrin IX can stimulate gene expression in K562 cells from enhancer elements containing binding sites for NF-E2. (nih.gov)
An occupational physician 1) distributed a symptom questionnaire, 2) interviewed employees, and 3) collected blood specimens to determine lead and zinc protoporphyrin (ZPP) levels. (cdc.gov)

Tin-protoporphyrin-mediated disruption in vivo of heme oxygenase-2 protein integrity and activity in rat brain. (nih.gov)
The present investigation compares the biochemical effects of Sn- and Zn-protoporphyrins on the predominant heme oxygenase isozyme present in the brain (HO-2) at activity, protein, and transcript levels and describes the ability of Sn-protoporphyrin to adversely affect this isozyme. (nih.gov)
Specifically, 6 h after a modest dose (50 mumol/kg, i.v.) of Sn-protoporphyrin, heme oxygenase activity in rat brain was nearly undetectable. (nih.gov)
The inducible form of heme oxygenase, HO-1, was not detectable by immunoblotting in brain microsomes of either control or Sn-protoporphyrin-treated animals. (nih.gov)
Northern blot analyses did not reveal decreases in the levels of the single HO-1 mRNA (1.8 kb) or the two HO-2 transcripts (1.3 and 1.9 kb), suggesting that Sn-protoporphyrin mediates its effects on heme oxygenase isozymes at the protein level. (nih.gov)

Tin(IV) protoporphyrin IX (Sn-protoporphyrin) potently inhibits heme degradation to bilirubin in vitro and in vivo, and it completely suppresses neonatal hyperbilirubinemia in experimental animals, including primates. (utmb.edu)

Protoporphyrin IX is an important precursor to biologically essential prosthetic groups such as heme, cytochrome c, and chlorophylls. (wikipedia.org)
The enhanced biliary excretion of unmetabolized heme following administration of Sn-protoporphyrin is a newly defined and biologically important response associated with use of this synthetic heme analogue. (utmb.edu)

An alternative name for heme is iron protoporphyrin IX (iron PPIX). (wikipedia.org)
Protoporphyrin IX reacts with iron salts in air to give the complex FeCl(PPIX). (wikipedia.org)

Protoporphyrin IX is an organic compound, classified as a porphyrin, that plays an important role in living organisms as a precursor to other critical compounds like heme (hemoglobin) and chlorophyll. (wikipedia.org)

The short-term lead concentrations for the three major jobs ranged from 215 to 307 ug/M3 during lead burning, 280 to 390 ug/M3 during tinning, and from 27 to 42 ug/M3 for grinding. (cdc.gov)