2) Cardiac death with symptoms suggestive of myocardial ischemia and presumed new ischemic EKG changes, or new LBBB, but death occurred before cardiac biomarkers were obtained or would be increased (type 3 MI). (aacc.org)
Indeed, serious episodes of cardiac ischemia (referred to herein as acute myocardial ischemia) typically result in either a subsequent AMI or VF, often within one to twenty-four four hours, sometimes within only a half an hour or less. (justia.com)
Accordingly, it would be highly desirable to provide a technique for reliably detecting acute myocardial ischemia so that the victim may be warned and medical attention sought. (justia.com)
Animal models of acute myocardial infarction include embolism of the coronary arteries, slow or rapid constriction of arteries, intimal sclerosis and narrowing by various techniques and, by dietary cholesterol, atherosclerosis leading to acute or subacute myocardial ischemia and infarction. (nih.gov)
Acute2
In this case, the clinical history of the exact time of the initial onset of chest pain is not clear in relation to the most recent acute event which brought the patient to the hospital. (aacc.org)
If sufficiently severe, cardiac ischemia results in an acute myocardial infarction (AMI), also referred to as a heart attack. (justia.com)
Cardiac7
To evaluate the diffusion changes occurring in neonatal brain ischemia, we used a robust quantitative diffusion technique, line-scan diffusion imaging (LSDI), which has been shown previously to yield high-quality images in neonates, children, and adults without the use of head restraints, cardiac gating, or specialized hardware (13-17) . (ajnr.org)
No. 12/360,822, filed Jan. 27, 2009, titled "System and Method for Distinguishing Among Cardiac Ischemia, Hypoglycemia and Hyperglycemia Using an Implantable Medical Device," which is a division of U.S. patent application Ser. (justia.com)
No. 11/043,612, filed Jan. 25, 2005, titled "System and Method for Distinguishing Among Cardiac Ischemia, Hypoglycemia and Hyperglycemia Using an Implantable Medical Device," now U.S. Pat. (justia.com)
The invention generally relates to implantable medical devices such as pacemakers and implantable cardioverter/defibrillators (ICDs) and, in particular, to techniques for detecting cardiac ischemia, hypoglycemia and hyperglycemia using such devices. (justia.com)
Cardiac ischemia is a condition whereby heart tissue does not receive adequate amounts of oxygen and is usually caused by a blockage of an artery leading to heart tissue. (justia.com)
Often AMI is preceded by episodes of cardiac ischemia that are not sufficiently serious to cause actual permanent injury to the heart tissue. (justia.com)
Episodes of cardiac ischemia may also trigger certain types of arrhythmias that may prove fatal, particularly ventricular fibrillation (VF) wherein the ventricles of the heart beat chaotically, resulting in little or no net flow of blood from the heart to the brain and other organs. (justia.com)
Ischemic5
It is unlikely that canine strokes can be diagnosed within the same rapid time frame as human strokes, and therefore the opportunity for thrombolytic intervention in ischemic strokes is unattainable. (frontiersin.org)
Ischemic conditioning has been shown to ameliorate ischemia-reperfusion injury in small animal models. (wjgnet.com)
Ischemic preconditioning refers to that performed before the duration of ischemia of the target organ. (wjgnet.com)
Ischemic perconditioning is performed over the duration of ischemia of the target organ. (wjgnet.com)
Ischemic postconditioning applies brief episodes of ischemia at the onset of reperfusion following a prolonged ischemia. (wjgnet.com)
Infarction2
Recent studies have documented that diffusion-weighted imaging can show areas of infarction in perinatal brain ischemia before abnormalities are apparent on conventional MR images (7, 11, 12) . (ajnr.org)
Ischemia, with or without overt infarction, can disrupt this integration and alter rhythmic stimulation, causing bradycardia or asystole or, more commonly, aberrant foci of electrical activity and fibrillation. (nih.gov)
Reperfusion2
Liver ischemia-reperfusion injury is a major cause of postoperative liver dysfunction, morbidity and mortality following liver resection and transplantation. (wjgnet.com)
It can be applied directly or remotely when cycles of ischemia and reperfusion are applied to a distant site or organ. (wjgnet.com)
Coronary2
Since Ms. Minnesota presented with symptoms suggestive of ischemia, and had no previous medical history of stent placement, percutaneous coronary intervention (PCI), or coronary artery bypass graft (CABG), we'll use the diagnostic criteria for MI following the Universal Definition guideline (See Box, right). (aacc.org)
Since the major risk factors can be shown to enhance atherogenesis, it is usually implied that their association with heart attack is through the ischemia resulting from coronary atherosclerosis. (nih.gov)
Elevation3
In a multivariate logistic regression analysis, the type of AMI was classified based on electrocardiography findings (odds ratio 5.18, 95% confidence interval: 1.69-15.91, P=0.004) and was independently associated with a long prehospital delay time, indicating that patients with ST segment elevation MI would seek early medical care. (who.int)
Ischemia is detected based on a shortening of the interval between the QRS complex and the end of a T-wave (QTmax), alone or in combination with a change in ST segment elevation. (justia.com)
By exploiting QTmax and QTend in combination with ST segment elevation, changes in ST segment elevation caused by hypo/hyperglycemia can be properly distinguished from changes caused by ischemia. (justia.com)
Clinical4
Stroke is the sudden onset of focal neurological deficits resulting from an intracranial vascular event with clinical signs lasting for at least 24 h ( 1 - 3 ). (frontiersin.org)
We reviewed the clinical records, laboratory results, and neuroimaging studies of 19 term neonates (between 38 and 42 weeks postconceptional age) ( Table 1 ) who were referred for MR imaging within the first 8 days of life to evaluate suspected perinatal brain ischemia. (ajnr.org)
To evaluate long-term clinical outcomes and survival in young-onset type 2 diabetes (T2DM) compared with type 1 diabetes (T1DM) with a similar age of onset. (diabetesjournals.org)
Clinical and mortality outcomes in 354 patients with T2DM, age of onset between 15 and 30 years (T2DM 15-30 ), were compared with T1DM in several ways but primarily with 470 patients with T1DM with a similar age of onset (T1DM 15-30 ) to minimize the confounding effect of age on outcome. (diabetesjournals.org)
Symptoms2
Even with the widespread use of cTn assays worldwide, there remains some confusion among clinicians and laboratorians about the timing, frequency, and duration for measuring cTn after patients present with symptoms suggestive of ACS. (aacc.org)
of symptoms, and common compli- the symptom interpretation and care- Fourteen patients were excluded be- cations include recurrent ischaemia, seeking behaviour. (who.int)
Focal1
Differences in LSDI of symmetric/diffuse and focal/multifocal lesions may reflect differences in pathophysiology or timing of the injury. (ajnr.org)
Duration1
Despite equivalent glycemic control and shorter disease duration, the prevalence of albuminuria and less favorable cardiovascular risk factors were greater in the T2DM 15-30 cohort, even soon after diabetes onset. (diabetesjournals.org)
Differences3
This timing varies due to differences in analytical sensitivity of cTn assays, as well as differences in patients' physiology. (aacc.org)
and (3) differential contractility responses occurred preferentially at times when circadian rhythms also showed strain-specific differences. (biomedcentral.com)
These effects were not detected at 10:00 AM, i.e., at another time-point when circadian genes showed no strain-specific differences. (biomedcentral.com)
Circulation2
The process of necrosis is not immediate in response to ischemia, and once necrosis occurs, it usually takes 1-4 hours for cTn to increase in the circulation before becoming detectable in the blood. (aacc.org)
Hypoxia is not identical with ischemia since hypoxia can occur while the circulation maintains the local concentrations of other ions and substrates. (nih.gov)
Include1
The neurologic sequelae of perinatal brain ischemia include seizures, spasticity, behavioral disturbances, and developmental delay. (ajnr.org)
Effects2
Neuroprotective strategies, including the early use of pharmacologic agents and induced cerebral hypothermia, may help to decrease the deleterious effects of brain ischemia (3) . (ajnr.org)
All effects occurred preferentially at the same time of the day, but varied as a function of the genetic origin of MSY. (biomedcentral.com)
Hours4
At this time, the FF voiced no health complaints to his wife and retired for the evening at approximately 2200 hours. (cdc.gov)
As the imaging features of both forms of strokes are highly representative of the underlying pathophysiologic stages in the hours to months following stroke onset, the descriptions of strokes at various stages are also discussed. (frontiersin.org)
Prehospital delay time ranged from 15 minutes to 10 days, with a median of 2 hours (interquartile range: 9.50). (who.int)
One hundred and twenty-six pa- within the first 2 hours after the onset tional variables (14,15,21) influenced tients were approached in the 2 months. (who.int)
Brain2
mean age, 2.6 days) with perinatal brain ischemia were evaluated using LSDI (1520/62.5/1 [TR/TE/excitations]) ( b maximum = 750 s/mm 2 ) and T1- and T2-weighted spin-echo (conventional) MR imaging. (ajnr.org)
This suggests that diffusion imaging may be useful in the early detection of perinatal brain ischemia and likely is to become crucial in the effective and safe use of neuroprotective strategies (7, 11, 12) . (ajnr.org)
Sensitive1
Moreover, the mitochondria are sensitive to ischemia and rapidly lose their ability to synthesize adenosine triphosphate, and are unable to maintain the energy requirements of the cell to live and function. (nih.gov)
Techniques2
Additionally, investigation into new imaging techniques may increase the sensitivity and specificity of stroke diagnosis, as well as provide new ways to monitor strokes over time. (frontiersin.org)
Techniques are described for detecting ischemia, hypoglycemia or hyperglycemia based on intracardiac electrogram (IEGM) signals. (justia.com)
Heart1
Hypertension increases the work and mass of the heart and creates a larger nutritional demand and relative ischemia. (nih.gov)
Change1
You can change these settings at any time, but that may impair functionality on our websites. (aacc.org)