• Its deletion from the MCF13 virus dramatically reduced the incidence of thymic lymphoma and increased the latency of disease in comparison with the wild-type virus. (archive.org)
  • In 1977, a transforming retrovirus was isolated from the AKR mouse. (wikipedia.org)
  • AKT8 was isolated from a spontaneous thymoma cell line derived from AKR mice by cocultivation with an indicator mink cell line. (wikipedia.org)
  • The origins of the Akt name date back to 1928, when J. Furth performed experimental studies on mice that developed spontaneous thymic lymphomas. (wikipedia.org)
  • Further inbreeding was undertaken with Ak mice at the Rockefeller Institute in 1936, leading to the designation of the AKR mouse strain. (wikipedia.org)
  • Selection of an immunoresistant Moloney lymphoma cell subline with decreased concentration of tumor specific antigens. (microbiologyresearch.org)
  • And I guess it was a very natural transition from that into the Polyoma virus which was the first real tumor virus that was worked with in this lab. (nih.gov)
  • But I've always felt that one of the key things to sort of opening up tumor virology was the isolation of a virus that you could work with in the lab that produced changes in tissue culture. (nih.gov)
  • 5. Prevention of murine radiogenic thymic lymphomas by tumor necrosis factor or by marrow grafting. (nih.gov)
  • 6. Stages in the development of radiation-induced thymic lymphomas in C57 BL/Ka mice: preleukemic cells become progressively resistant to the tumor preventing effects of a bone marrow graft. (nih.gov)
  • 15. Tumor necrosis factor and interferon gamma inhibit the development of radiation-induced thymic lymphomas in C57BL/Ka mice. (nih.gov)
  • 20. Analysis of tumor-associated alkyldiacylglycerols and other lipids during radiation-induced thymic leukemogenesis. (nih.gov)
  • X-irradiation of C57BL/6 mice induces thymic lymphosarcomas which sometimes contain retroviruses which upon injection into normal mice mimic the effect of the irradiation. (microbiologyresearch.org)
  • 9. Thymic lymphosarcomas obtained by X-rays in association with a weakly leukemogenic virus: cellular studies. (nih.gov)
  • PMID- 214398 TI - Characterization of an adenosine triphosphatase of the avian myeloblastosis virus and the virus-infected myeloblast. (nih.gov)
  • Serological characterization of C-type retroviruses endogenous to the C57BL/6 mouse and isolated in tumours induced by radiation leukaemia virus (RadLV-Rs). (microbiologyresearch.org)
  • Radiation-induced murine leukemias and endogenous retroviruses: the time course of viral expression. (microbiologyresearch.org)
  • 14. Dendritic cells prevent radiation-induced thymic lymphoma. (nih.gov)
  • Antibody-induced modulation of Friend virus cell surface antigens decreases virus production by persistent erythroleukemia cells: influence of the Rfv-3 gene. (microbiologyresearch.org)
  • AB - Peripheral blood mononuclear cells from donors of known serological status with respect to EB virus were exposed to the virus in vitro and then cultured at various cell concentrations. (nih.gov)
  • The results strongly suggest that the regression phenomenon is an in vitro expression of long-term T-cell-mediated immunity to EB virus which the large majority, if not all, infected individuals possess. (nih.gov)
  • I. Complete regression of virus-induced transformation in cultures of seropositive donor leukocytes. (nih.gov)
  • In 1977, a transforming retrovirus was isolated from the AKR mouse. (wikipedia.org)
  • So, we got rather deeply into mouse viruses. (nih.gov)
  • PMID- 214405 TI - Long-term T-cell-mediated immunity to Epstein-Barr virus in man. (nih.gov)
  • PMID- 214407 TI - Antibodies to Herpes simplex virus types 1 and 2 in patients with squamous-cell carcinoma of uterine cervix in India. (nih.gov)
  • AB - Antibody activity to Herpes simplex virus type-1 (HSV-1) and type-2 (HSV-2) was measured by the indirect hemagglutination (IHA) test in sera from 124 women with squamous-cell carcinoma of the uterine cervix, 46 women with non-cervical cancer and 116 matched normal women. (nih.gov)