ThrombocytopeniaHigh platelet countIncreased platelet countDisordersThrombosisCountsHigher plateletThrombocythemiaCountAbnormalWillebrand DiseaseThrombocytesSecondaryImpaired platelet functionExtreme thrombocytosisOverproduction of plateletsRole of plateletsReactiveBoneAnemiaInflammationColorlessAspirinInfectionAggregationLeukocyteMegakaryocytesSymptomsDisorderTransfusionsDiagnosisHydroxyureaSpleenMechanismsInflammatoryDiseasesPretreatmentDefectsImmatureBleedingRatioCirculateMalignantBlood cellsPatientsNormalCytoplasmGeneticPrimaryFibrin
Thrombocytopenia10
- If your blood has a low number of platelets , it is called thrombocytopenia. (medlineplus.gov)
- Immune thrombocytopenia (ITP) is a type of platelet disorder . (nih.gov)
- This study is investigating the safety and efficacy of platelet transfusion as a treatment for infants with thrombocytopenia. (nih.gov)
- This study investigates immature platelet counts as a marker for bleeding risk in newborns with thrombocytopenia, compared with platelet counts alone. (nih.gov)
- 6. Kuter D.J., Rosenberg R.D. The reciprocal relationship of thrombopoietin (c-Mpl ligand) to changes in the platelet mass during busulfan-induced thrombocytopenia in the rabbit // Blood. (medline.ru)
- We can have too many blood platelets (as in thrombocytosis) or too little blood platelets (as in thrombocytopenia) or the wrong type of blood platelets (as in some rare disorders). (positivehealth.com)
- The platelet count is normally 140,000 to 440,000/mcL (140 to 440 × 10 9 /L). However, the count can vary slightly according to menstrual cycle phase, decrease during near-term pregnancy (gestational thrombocytopenia), and increase in response to inflammatory cytokines (secondary, or reactive, thrombocytosis). (msdmanuals.com)
- For individuals with known medical conditions that affect blood cell counts, such as anemias, leukemias, or thrombocytopenia (low platelet count), regular CBC tests are performed to monitor the progression of the condition and evaluate the effectiveness of treatment. (dailyexcelsior.com)
- Overview Thrombocytopenia is the medical term for low platelet count. (entirelyhealth.com)
- However, this mechanism may not be efficient enough to produce sufficient platelet numbers under conditions of increased platelet consumption, such as inflammation/infection, immune thrombocytopenia, or traumatic blood loss. (rupress.org)
High platelet count8
- If another disease or condition is causing the high platelet count, it is thrombocytosis. (medlineplus.gov)
- Generally, high platelet count usually makes your blood clot unnecessarily throughout the body, which may prove lethal in some cases. (medguidance.com)
- In order to apply a right treatment plan for high platelet count, it is important to identify the underlying cause first. (medguidance.com)
- In some situations, it is important to use medicines that would help lower high platelet count. (medguidance.com)
- Your doctor may suggest plateletpheresis if you're having stroke due to your high platelet count. (medguidance.com)
- However, an abnormally high platelet count means that clotting could happen spontaneously. (drinksavvyinc.com)
- Once-daily low-dose aspirin (80 mg/day) is often recommended as a means of reducing thrombosis risk and reduce high platelet count. (mrlabtest.com)
- Which values are considered a high platelet count in the blood? (mrlabtest.com)
Increased platelet count3
- Thrombocytosis, an increased platelet count above the upper limit of normal (ULN) range, is common in infants and children. (medscape.com)
- In reactive thrombocytosis, no specific physical findings are related to the increased platelet count. (medscape.com)
- Essential Thrombocythemia Essential thrombocythemia (ET) is a myeloproliferative neoplasm characterized by an increased platelet count, megakaryocytic hyperplasia, and a hemorrhagic or microvascular vasospastic tendency. (msdmanuals.com)
Disorders6
- What Are Platelet Disorders? (medlineplus.gov)
- This study is looking at people who have platelet or other blood disorders. (nih.gov)
- Our laboratory is interested in genetic disorders of bleeding and thrombosis, focusing on blood platelets as the tools to understand the molecular basis of these disorders in humans. (ny.gov)
- Blood platelets are generated from bone marrow stem cells, serving not only to control normal bleeding, but involved also in excessive clotting that may predispose to pathological disorders such as heart attacks and stroke. (ny.gov)
- Genomic and proteomic applications in diagnosis of platelet disorders and classification. (ny.gov)
- If you have a high number of platelets in the blood you will experience vasomotor symptoms, including headache, visual changes, syncope or chest pain) and cardiovascular disorders. (mrlabtest.com)
Thrombosis8
- Rarely, in patients who have reactive thrombocytosis and a known risk factor for thrombosis, such as factor V Leiden mutation, the thrombotic risk may be increased. (medscape.com)
- Apart from IDA, other hematologic abnormalities seen in patients with CD are thrombocytosis, splenic hypofunction, leukopenia, IgA deficiency, enteropathy-associated T cell lymphoma (EATL), and rarely venous thromboembolism (VTE), including deep venous thrombosis (DVT) and pulmonary embolism (PE). (hindawi.com)
- 13. Vannucchi A., Barbui T. Thrombocytosis and thrombosis // Hematology Am. Soc. (medline.ru)
- and for leukemia‐free survival were prefibrotic PMF morphology, thrombosis and extreme thrombocytosis (platelets >1 million/μl). (senorcafe.com)
- Reactive thrombocytosis is not typically associated with an increased risk of thrombosis or bleeding. (msdmanuals.com)
- BCR-ABL1-negative myeloproliferative neoplasm (MPN) characterized by a sustained elevation of platelet number with a tendency for thrombosis and haemorrhage. (capsulehealth.one)
- Platelets are anucleate blood cells, long known to be critically involved in hemostasis and thrombosis. (comprehensivephysiology.com)
- Frequency and characteristics of the JAK2 V617F mutation in 23 cerebral venous sinus thrombosis patients with thrombocytosis. (cdc.gov)
Counts6
- The physiologic reference range of platelet counts is 150-400 X 10 9 /L. A platelet count exceeding the upper limit is called thrombocytosis or thrombocythemia. (medscape.com)
- Patients with very high platelet counts may be tested for acquired von Willebrand disease, a blood disorder that can impair normal blood clotting and cause major bleeding. (lls.org)
- High platelet counts can limit how well the von Willebrand proteins clot. (lls.org)
- Time course of platelet counts in critically ill patients // Crit. (medline.ru)
- Studies have shown that most people who have platelet counts over 500,000 have secondary thrombocytosis. (hoacny.com)
- There is an inverse relationship between VWF levels and platelet counts. (capsulehealth.one)
Higher platelet2
- http://dx.doi.org/10.1083/jcb.201410052 ) show that platelet release from megakaryocytes can be induced by interleukin-1α (IL-1α) via a new rupture mechanism, which yields higher platelet numbers, occurs independently of the key regulator of megakaryopoiesis thrombopoietin, and may occur during situations of acute platelet need. (rupress.org)
- Reactive thrombocytosis does not usually exceed 800 x 10 3 platelets/µl in adults compared with primary thrombocytosis, which has much higher platelet count. (mrlabtest.com)
Thrombocythemia8
- Primary thrombocytosis (also called essential thrombocytosis, essential thrombocythemia, or primary thrombocythemia) consists of 2 types. (medscape.com)
- 12. Ruggeri M., Tosetto A., Frezzato M., Rodeghiero F. The rate of progression to polycythemia vera or essential thrombocythemia in patients with erythrocytosis or thrombocytosis // Ann. (medline.ru)
- What are the Risk Factors in Thrombocythemia and Thrombocytosis? (hoacny.com)
- Secondary thrombocytosis is more common than primary thrombocythemia. (hoacny.com)
- The experts usually divide it into two different categories - primary thrombocythemia and secondary thrombocytosis. (medguidance.com)
- Your healthcare provider may use different approaches to treat primary thrombocythemia and secondary thrombocytosis. (medguidance.com)
- Essential thrombocythemia (ET) was the most common cause of primary thrombocytosis. (drinksavvyinc.com)
- It may be due to essential thrombocythemia, a rare chronic blood cancer characterized by the overproduction of platelets. (mrlabtest.com)
Count45
- In ITP, your blood does not clot as it should, because you have a low platelet count. (nih.gov)
- When you have a low platelet count, you may have trouble stopping bleeding. (nih.gov)
- This test measures your platelet count and the number of other blood cells in your blood. (nih.gov)
- Most people who have chronic ITP can stop treatment at some point and maintain a safe platelet count. (nih.gov)
- Treatment depends on your platelet count and whether you have any symptoms. (nih.gov)
- In mild cases, you may not need any treatment, and your provider will monitor your condition to make sure that your platelet count does not become too low. (nih.gov)
- If your ITP was caused by an infection, treating the infection may help increase your platelet count and lower your risk of bleeding problems. (nih.gov)
- The aim of the study was to evaluate the effective prognostic impact of inflammatory biomarkers such as platelet count, platelet to lymphocyte ratio (PLR), and IL-6 in cervical cancer patients. (nih.gov)
- Cutoff level of pretreatment platelet count and PLR was identified by using the ROC curve. (nih.gov)
- A higher pretreatment platelet count and PLR value associated with higher IL-6 tumoral expression could be used to predict poor prognosis in cervical cancer patients. (nih.gov)
- Thrombocytosis may require treatment when the platelet count exceeds 1 million/μL. (medscape.com)
- Multiple modalities have been used to reduce the platelet count or inhibit their thrombotic effects, including hydroxyurea, aspirin, or plateletpheresis (collection and removal of platelets from the circulation). (medscape.com)
- Therefore, serum potassium levels and the platelet count should be monitored carefully during therapy. (drugs.com)
- In patients with ET, the platelet count is higher than normal. (lls.org)
- Does your infant have a low platelet count? (nih.gov)
- To participate in this study, your child must be younger than 6 months old and have a low platelet count (less than 100 × 109/L). This study takes place in Boston, Massachusetts. (nih.gov)
- To participate in this study, you must have a newborn who is less than 32 weeks' gestational age, has a birth weight greater than 500 grams, and has a platelet count less than 100 × 109/L. This study takes place in multiple locations in the United States, the Netherlands, and Sweden. (nih.gov)
- Murine thrombopoietin mRNA levels are modulated by platelet count // Blood. (medline.ru)
- Blunted rise in platelet count in critically ill patients is associated with worse outcome // Crit. (medline.ru)
- The optimal screening strategy used a combination of haemoglobin and platelet count and "1 of 2 abnormal" as the criterion for positivity. (bmj.com)
- Haemoglobin and platelet count provide a useful screening test combination for patients with suspected IBD. (bmj.com)
- Various laboratory blood tests including haemoglobin, platelet count, erythrocyte sedimentation rate (ESR), C reactive protein (CRP), and albumin are widely used as preliminary screening tests for IBD. (bmj.com)
- A laboratory test can help you find your platelet count. (medguidance.com)
- If you have more platelets in your blood, it means your platelet count is higher, which may be caused by many conditions and lead to several complications. (medguidance.com)
- When your lab report confirms, "platelet count high", it is important to find the underlying cause. (medguidance.com)
- You may notice your platelet count going up due to some other health conditions. (medguidance.com)
- Your doctor will prescribe these medicines when your platelet count is over 1 million. (medguidance.com)
- Usually used to treat cancers, this medicine can help lower your platelet count. (medguidance.com)
- Some experts may use this medicine to lower your platelet count, but the research has shown that it is not as effective as hydroxyurea is. (medguidance.com)
- It is another available treatment option to lower platelet count, but about 20% of patients fail to handle its side effects. (medguidance.com)
- The procedure helps lower your platelet count at a rapid pace, so it is a suitable choice in emergencies only. (medguidance.com)
- A blood platelet count is a blood test that measures the average number of platelets in the blood. (labtestsguide.com)
- During a CBC test, the platelet count (PC) is a measurement that indicates the total quantity of platelets present in your blood sample. (dailyexcelsior.com)
- What does it mean when your platelet count is high? (drinksavvyinc.com)
- What should I do if my platelet count is high? (drinksavvyinc.com)
- The platelet count of a healthy person is between 150, 000 to 450,000 [1] per microliter of blood. (entirelyhealth.com)
- What is a high count of platelets in the blood called? (mrlabtest.com)
- A platelet count above the normal rate in blood test is called thrombocytosis. (mrlabtest.com)
- It may be due to iron deficiency anemia where platelets count does not usually exceed 500 x 10 3 /µl in adults. (mrlabtest.com)
- The diagnosis is based on a platelet count above 1000 x 10 3 /µl and when a reactive or secondary thrombocytosis is excluded. (mrlabtest.com)
- Which factors can increase the platelet count in the blood? (mrlabtest.com)
- Which diseases can increase your platelet count in the blood? (mrlabtest.com)
- What can I do to lower the platelet count in the blood? (mrlabtest.com)
- Where can I find more information about platelet count in the blood? (mrlabtest.com)
- 0.001).Significant variation by sex was observed for the platelet count. (bvsalud.org)
Abnormal1
- Primary or essential: Abnormal cells in the bone marrow cause an increase in platelets. (mrlabtest.com)
Willebrand Disease2
- For example, in von Willebrand Disease, your platelets cannot stick together or cannot attach to blood vessel walls. (medlineplus.gov)
- Von Willebrand Disease Von Willebrand disease (VWD) is a hereditary quantitative deficiency or functional abnormality of von Willebrand factor (VWF), which causes platelet dysfunction. (msdmanuals.com)
Thrombocytes4
- Platelets, also known as thrombocytes, are blood cells. (medlineplus.gov)
- Platelets, also known as thrombocytes, are small, colorless, irregularly-shaped blood cells that play a crucial role in the process of blood clotting (hemostasis). (labtestsguide.com)
- Platelets, or thrombocytes, are a type of cell present in the blood that help it to clot. (entirelyhealth.com)
- An increased number of thrombocytes (platelets) in the blood, without a known cause. (takesurveys.onl)
Secondary4
- Thrombocytosis is classified as either primary or secondary. (medscape.com)
- Sutor A.H. Primary and secondary thrombocytosis in childhood // Br. (medline.ru)
- You might be at risk for secondary thrombocytosis if you have a disease, condition, or factor that can cause it. (hoacny.com)
- It is usually related to secondary or reactive thrombocytosis due to an infection, an inflammatory disease ( ulcerative colitis , arthritis , celiac disease , etc.) or produced by medication. (mrlabtest.com)
Impaired platelet function2
- Hence, reduced platelet numbers and/or impaired platelet function, as found in the context of numerous pathologies or upon pharmacological intervention, may have a negative impact on a large variety of physiological processes and under certain circumstances can become life threatening ( Sachs and Nieswandt, 2007 ). (rupress.org)
- The bleeding diathesis is not due to impaired platelet function but rather to an acquired Von Willebrand's disease caused by proteolytic reduction of Von Willebrand Factor (VWF) multimers. (capsulehealth.one)
Extreme thrombocytosis2
- 15. Wiwanitkit V. Extreme thrombocytosis: what are the etiologies? (medline.ru)
- 19. Buss D.H., Cashell A.W., O Connor M.L., Richards F. Occurrence, etiology, and clinical significance of extreme thrombocytosis: a study of 280 cases // Am. J. Med. (medline.ru)
Overproduction of platelets1
- previously called a myeloproliferative disorder) involving overproduction of platelets because of a clonal abnormality of a hematopoietic stem cell. (msdmanuals.com)
Role of platelets1
- This article reviews the role of platelets in inflammation and immune responses, and highlights their interactions with other immune cells, including examples of major functional consequences of these interactions. (comprehensivephysiology.com)
Reactive3
- Normally, no treatment is necessary for reactive thrombocytosis. (medscape.com)
- If reactive thrombocytosis is obvious, no further diagnosis or specific treatment is necessary. (medscape.com)
- No extensive diagnostic workup is needed if the primary causes of reactive thrombocytosis are apparent. (medscape.com)
Bone8
- Platelets are tiny blood cells that are made in the bone marrow. (nih.gov)
- For our NYSTEM proposal, we have developed novel means of infecting bone marrow stem cells to specifically target the deficient protein (factor VIII) in bone marrow stem cells that are the precursors for circulating blood platelets. (ny.gov)
- 11. Sungaran R., Chisholm O.T., Markovic B. The role of platelet alpha-granular proteins in the regulation of thrombopoietin messenger RNA expression in human bone marrow stromal cells // Blood. (medline.ru)
- Thrombopoietin helps control the number of circulating platelets by stimulating the bone marrow to produce megakaryocytes, which in turn shed platelets from their cytoplasm. (msdmanuals.com)
- Thrombopoietin is produced in the liver at a constant rate and its circulating level is determined by how much is bound to circulating platelets and possibly to bone marrow megakaryocytes and the extent to which circulating platelets are cleared. (msdmanuals.com)
- Overview of Myeloproliferative Neoplasms Myeloproliferative neoplasms are clonal proliferations of bone marrow stem cells, which can manifest as an increased number of platelets, red blood cells (RBCs), or white blood cells (WBCs). (msdmanuals.com)
- In this disease, your bone marrow starts making too many platelets without any particular reason. (medguidance.com)
- Platelets are continuously produced by fragmentation of the cytoplasm of their giant polyploid precursors in the bone marrow, the megakaryocytes. (rupress.org)
Anemia1
- In addition, primary thrombocytosis due to myeloproliferative disorder is commonly associated with anemia and leukocytosis. (medscape.com)
Inflammation2
- Platelets, small anucleate cells that circulate in the blood stream, are essential for normal hemostasis but also play major roles in inflammation, immunity, wound healing, tumor metastasis, and the development and maintenance of lymph vessels ( Leslie, 2010 ). (rupress.org)
- In addition to their role in blood clots, increasing evidence reveals significant roles for platelets in inflammation and immunity. (comprehensivephysiology.com)
Colorless2
- Platelets are small, colorless blood cells-like structures, which are essential for blood clotting and help plug damaged blood vessels. (medguidance.com)
- Platelets are colorless blood cells that help your blood clot. (entirelyhealth.com)
Aspirin2
- In vasculitis syndrome with thrombocytosis (in particular, in Kawasaki syndrome), treatment with aspirin is recommended. (medscape.com)
- When platelet function is reduced (eg, as a result of uremia, or use of nonsteroidal anti-inflammatory drug [NSAID] or aspirin ), the risk of bleeding increases. (msdmanuals.com)
Infection1
- A moderate thrombocytosis may be due to an infection (respiratory, gastrointestinal or urinary). (mrlabtest.com)
Aggregation2
- Pro-inflammatory upregulation of cytokines such as IL-6 has been implicated in cervical cancer development and progression through several mechanisms, for example, by inducing platelet production, activation, and aggregation. (nih.gov)
- Some products sold at pharmacy, such as Ginkgo or Ginseng may help to reduce platelet aggregation. (mrlabtest.com)
Leukocyte2
- Therapeutic apheresis includes: plasma exchange, red cell exchange, platelet and leukocyte depletion and photopheresis. (rwjbh.org)
- Major cell adhesion molecule interactions include (platelet‐leukocyte) P‐selectin‐PSGL‐1 and GP1bα‐Mac‐1. (comprehensivephysiology.com)
Megakaryocytes2
- If you have ET, your marrow will show a significant increase in platelet-forming cells (megakaryocytes). (lls.org)
- This work provides for the first time an explanation of how megakaryocytes can maintain platelet mass equilibrium and quickly restore platelet numbers under pathological conditions associated with increased platelet turnover. (rupress.org)
Symptoms2
- When you have symptoms that may be due to a platelet disorder. (labtestsguide.com)
- A mild thrombocytosis with no symptoms attached is not a matter for concern. (mrlabtest.com)
Disorder6
- You may need this test to confirm that you have ITP and not another platelet disorder, especially if your treatment is not working. (nih.gov)
- Because of the rarity of this disorder and the largely anecdotal character of many reports, the roles of antibiotics and antiplatelet agents (for the treatment of thrombocytosis) have not been formally addressed. (medscape.com)
- Do you or your child have a platelet, bleeding, or white blood cell disorder? (nih.gov)
- To participate in this study, you must be a child or adult who either is healthy or has a platelet disorder, coagulation disorder, or white blood cell disorder. (nih.gov)
- is platelet overproduction in response to another disorder. (msdmanuals.com)
- Disorder characterized by a decrease or lack of platelet dense bodies in which the releasable pool of adenine nucleotides and 5HT are normally stored. (bvsalud.org)
Transfusions1
- For more serious cases, you may need medicines or blood or platelet transfusions . (medlineplus.gov)
Diagnosis2
- Children suspected of having primary thrombocytosis require a referral to a hematologist to establish diagnosis and for proper management. (medscape.com)
- Splenomegaly and the number of leukocytes and platelets are very useful markers in the initial clinical diagnosis of PV 6) . (ispub.com)
Hydroxyurea1
- Your doctor might prescribe platelet-lowering drugs primarily in the form of hydroxyurea (Droxia, Hydrea) or interferon alfa (Intron A). Platelets can be removed from your blood by a procedure that's similar to dialysis. (drinksavvyinc.com)
Spleen1
- Platelets are eventually destroyed by apoptosis, a process independent of the spleen. (msdmanuals.com)
Mechanisms1
- Platelets interact with leukocytes through both adhesive mechanisms as well as release of cytokines/chemokines. (comprehensivephysiology.com)
Inflammatory2
- Researchers are looking at the positive effects of platelet transfusion against the negative effects, such as the release of inflammatory molecules and the formation of blood clots. (nih.gov)
- Interleukin-6 stimulates thrombopoiesis through thrombopoietin: role in inflammatory thrombocytosis // Blood. (medline.ru)
Diseases1
- We have developed a unique infrastructure for studying the genetics of platelet diseases using RNA profiling techniques. (ny.gov)
Pretreatment1
- Incorporation of pretreatment leukocytosis and thrombocytosis into the FIGO staging system for prognosis in surgically treated endometrial cancer. (cdc.gov)
Defects1
- Qualitative Platelet Defects (incl. (sharecare.com)
Immature1
- Immature platelets are the most recently produced platelets and may be a better marker of platelet production. (nih.gov)
Bleeding5
- Your platelets will clot (clump together) to plug the hole in the blood vessel and stop the bleeding. (medlineplus.gov)
- Any of these conditions, even those in which platelets are markedly increased, may cause defective formation of hemostatic plugs and bleeding. (msdmanuals.com)
- Platelets help blood heal wounds and prevent excessive bleeding. (labtestsguide.com)
- Platelets are cellular components of the blood responsible for forming blood clots to halt bleeding. (dailyexcelsior.com)
- Platelets are important for the body as they clump or stick together in response to injury and prevent excessive bleeding. (drinksavvyinc.com)
Ratio2
- Hypercoagulation detected by fibrinogen/platelet ratio (FPR) ≥ 42 was found in 15/51 (29%) patients, mostly in high thrombotic risk group, 13 (52%) out of 25 had hypercoagulability. (lww.com)
- Conclusion : Certains paramètres tels que la lymphopénie et l'éosinopénie présentent une valeur diagnostique importante, alors que d'autres paramètres tels que le NLR (Neutrophils-to-lymphocytes ratio), le MLR (Monocyte -to-lymphocytes ratio) et le PLR (Platelet-to-lymphocytes ratio) offrent une valeur pronostique très précieuse. (bvsalud.org)
Circulate1
- Platelets circulate for 7 to 10 days. (msdmanuals.com)
Malignant1
- Thrombocytosis is an emerging risk marker of malignant cancer, so it I s very important to study any unexplained thrombocytosis. (mrlabtest.com)
Blood cells3
- This test measures the number red blood cells, white blood cells and platelets in a sample of blood. (lls.org)
- Imbalances can occur in all the different components of the blood, such as in the red blood cells, blood platelets, white blood cells, plasma or other components of the blood. (positivehealth.com)
- This affects your platelets the most, but the condition sometimes involves white and red blood cells as well. (medguidance.com)
Patients5
- In patients with ET, the platelets may appear enlarged and/or clumped together. (lls.org)
- Out of 25 high thrombotic risk patients, 3/25 (12%) had hyperfibrinogenemia and 11/25 (44%) had hyperfibrinogenemia combined with thrombocytosis. (lww.com)
- The incidence of hyperfibrinogenemia/thrombocytosis between patients with recent trauma and other thrombogenic risk factors was similar, 8/15 (53%) vs. 5/9 (55%), respectively. (lww.com)
- L'objectif de notre étude est de décrire les caractéristiques hématologiques des patients atteints de COVID-19 hospitalisés au niveau du CHU d'Oran en Algérie. (bvsalud.org)
- Patients et méthodes : Il s'agit d'une étude prospective menée entre le 1er Juillet et le 15 Octobre 2020 ayant inclus des patients hospitalisés et/ou suivis au niveau des unités COVID-19 du CHU Oran en Algérie. (bvsalud.org)
Normal1
- Hypokalemia and thrombocytosis could occur upon conversion of severe megaloblastic to normal erythropoiesis with B 12 therapy. (drugs.com)
Cytoplasm1
- Circulating platelets were thought to arise solely from the protrusion and fragmentation of megakaryocyte cytoplasm. (rupress.org)
Genetic2
- The researchers will use a blood sample to look for problems with platelets and a possible genetic cause in the participant's DNA or RNA. (nih.gov)
- Multiplexed genetic profiling of human blood platelets using fluorescent microspheres. (ny.gov)
Primary1
- In primary thrombocytosis, prophylactic use of antithrombotic agents has not been well delineated. (medscape.com)
Fibrin2
- On the transaction, they show darker grey lines of aggregated platelets interspersed between paler layers of coagulated fibrin. (senorcafe.com)
- A) Platelets localize to the site of injury, binding to fibrin, and forming a hemostatic plug. (comprehensivephysiology.com)