• BRD4 protein recognizes acetylated lysine residues on proteins and by doing so participates in the regulation of DNA replication, DNA transcription, and thereby key cellular processes involved in the development of neoplasms (i.e. malignant or benign tissue growths). (wikipedia.org)
  • Nonmesotheliomatous cancers of the pleura include an assortment of malignant neoplasms that primarily or secondarily involve pleura. (medscape.com)
  • By definition, pseudomesotheliomatous carcinoma refers to an epithelial neoplasm that secondarily involves the pleura and encases the lung, thereby simulating the radiologic and macroscopic appearance of malignant mesothelioma. (medscape.com)
  • The term fibroma is inappropriate because the neoplasm exhibits defined histologic features that differ from those of fibromas and may express malignant behavior. (medscape.com)
  • Synovial sarcoma is a malignant soft-tissue neoplasm that most commonly affects the extremities near to, but not in continuity with, large joints. (medscape.com)
  • In summary, the present study found that ex situ hepatectomy and liver autotransplantation are suitable surgical techniques for treating a giant SFT, as well as other liver neoplasms that are considered unresectable by conventional surgery. (spandidos-publications.com)
  • BACKGROUND: This study aimed to investigate the value and efficiency of routine brain MRI or CT in the preoperative workup for patients with potentially resectable (cT1-4a N0-3 ) thoracic esophageal squamous cell cancer (ESCC). (bvsalud.org)
  • Background: Research on predicting disease-specific survival (DSS) in patients with esophageal squamous cell carcinoma (ESCC) of the thoracic segment with pT1 to 2 lymph node metastases is insufficient. (researchsquare.com)
  • Therefore, it's time for pathologists to update their knowledge and skills in the diagnosis of thoracic pathology in an intimate mentoring environment that unites experienced experts with pathologists desiring a contemporary review of modern thoracic pathology. (medical-book.net)
  • Squamous cell carcinomas are the most common esophageal neoplasm worldwide and still account for about 70-85% of cases, adenocarcinoma now surpassess SCC as the predominant histologic type in the United States [1,7,30,39]. (auntminnie.com)
  • Participants will receive pembrolizumab 200 mg intravenously (IV) every 3 weeks (Q3W) in combination with 3 cycles of the investigator's choice of platinum doublet chemotherapy and concurrent standard thoracic radiotherapy (60 Gray (Gy) over 6 weeks) followed by pembrolizumab plus olaparib placebo twice a day (BID) for approximately 1 year. (clinicaltrials.gov)
  • The association also publishes the Journal of Thoracic Oncology, the primary educational and informational publication for topics relevant to the prevention, detection, diagnosis, and treatment of all thoracic malignancies. (eurekalert.org)
  • S pinal meningiomas are encountered mostly in the thoracic region in middle-aged women, 1, 11 but occur elsewhere along the spinal canal. (thejns.org)
  • Initially, it was regarded as occurring in the midline areas of the upper respiratory tract, upper digestive tract, and mediastinum (i.e. central compartment of the thoracic cavity) of young adults and to lesser extents children and infants. (wikipedia.org)
  • Historically, 2 chest tubes are used to drain the thoracic cavity postoperatively. (medscape.com)
  • DSRCT was first described by Gerald and Rosai in 1989 as a primitive neoplasm of children and young adults that most frequently occurs in the serosa of the pelvic cavity. (medscape.com)
  • The newly developed nomogram can accurately forecast DSS in patients with thoracic segment ESCC and pT1-2 lymph node metastasis. (researchsquare.com)
  • Dr. Arthur McUnu Jr, MD is a Thoracic Surgery Specialist in Germantown, TN. (sharecare.com)
  • In complex cases, thoracic surgeons perform open surgery. (bookinghealth.com)
  • Changes in surgical practice have resulted innovations in video-assisted thoracic surgery (VATS) and enhanced recovery after surgery (ERAS). (biomedcentral.com)
  • Currently, videoscopic thoracic surgery has introduced a whole new array of minimally invasive options. (medscape.com)
  • The continued evolution of cardiac surgery has made the median sternotomy and its many variations one of the most widely used incisions in for cardiac surgery, which are occasionally used for thoracic surgery. (medscape.com)
  • Previous abdominal/thoracic surgery. (who.int)
  • Founded in 1974, the association's membership includes nearly 7,500 lung cancer specialists across all disciplines in over 100 countries, forming a global network working together to conquer lung and thoracic cancers worldwide. (eurekalert.org)
  • Lung and breast cancers are more likely to affect the thoracic spine. (medscape.com)
  • It is generally accepted that the BRD4-NUT protein promotes these neoplasms by maintaining their neoplastic cells in a perpetually undifferentiated, proliferative state. (wikipedia.org)
  • The panorama includes neoplasms and non-neoplastic entities. (medical-book.net)
  • Anatomically, neoplasms of the spinal cord may be classified according to the compartment of origin, either intramedullary (inside the cord) or extramedullary (outside the cord). (medscape.com)
  • Most frequently, metastatic seeding involves the thoracic spine (accounting for about 70% of cases), with the lumbar spine being the next most involved site (20% of cases). (medscape.com)
  • Surgical stabilization of fracture and fracture dislocations of the thoracic spine. (athletesandinjuries.com)
  • There are seven cervical vertebrae, twelve thoracic vertebrae , and five lumbar vertebrae in the spine. (athletesandinjuries.com)
  • SFTs of the pleura are localized mesenchymal neoplasms composed of fibroblastlike cells believed to arise from the subpleural connective tissue. (medscape.com)
  • Thoracic specimens are commonly encountered in clinical practice derived from biopsy and surgical procedures on pulmonary, cardiovascular and mediastinal tissue. (medical-book.net)
  • The upper trunk of the brachial plexus, the suprascapular nerve, the long thoracic nerve, and the axillary nerves are the most commonly involved. (boneandspine.com)
  • Inclusion criteria: Patients undergoing Abdominal/Thoracic oncosurgeries. (who.int)
  • Strict layered closure is the rule in thoracic surgical incisions. (medscape.com)
  • Acute poliomyelitis, adhesive capsulitis, amyotrophic lateral sclerosis, cervical radiculopathy, HIV Infection, mononeuritis Multiplex, neoplasm, polymyalgia rheumatic, rotator cuff disease and thoracic outlet syndrome need to be considered as differentials when examining a patient with the presentation as above. (boneandspine.com)
  • A chest radiograph or other imaging and pulmonary function tests [American Thoracic Society 2004]. (cdc.gov)
  • There is enough evidence to suggest that depression among patients with thoracic neoplasms is associated with treatment delays and changes in primary treatment, especially delays due to pandemic, were associated with lower survival rates than those without changes," Dr. Arrieta reported. (eurekalert.org)
  • These patients are treated in collaboration with thoracic surgeons. (bookinghealth.com)
  • With appropriate clinical indications, neoplasms can be removed during bronchoscopy - a sparing interventional procedure. (bookinghealth.com)
  • In the early days, prior to the development of general anesthesia and positive pressure ventilation, the incisions were mostly small and were used predominantly to drain localized infectious complications, or they were ingeniously designed to be used via an extra pleural approach especially to lower thoracic structures. (medscape.com)
  • Further studies are needed to confirm and expand these views and to determine if any of the overexpressed gene products of the BRD4-NUT protein contribute to the development and/or progression, or can serve as targets for the treatment, of the neoplasms associated with the BRD4-NUTM1 fusion gene. (wikipedia.org)
  • A group of asteropygine trilobites with 10 thoracic segments from the lower Emsian to lowermost Eifelian of western Europe and northwest Africa is deemed monophyletic. (ac.be)
  • Overexpression of the MYC and SOX2 genes can also act to maintain cells in an undifferentiated stem cell-like state similar to the cells in the neoplasms driven by the BRD4-NUTM1 fusion gene. (wikipedia.org)
  • These questions also apply to a wide range of neoplasms that have more recently been associated with the NUTM1 gene fused to other genes. (wikipedia.org)
  • Special incisions that include partial sternotomies and first rib resections require a thorough knowledge of the anatomy of the base of the thoracic cage. (medscape.com)